Clinical trials: Cephalalgia
Migraine
Migraine and High Flow Oxygenotherapy at the Emergency Department (MiOx)
Migraine is a common pathology, affecting around 12% of the general population, up to 25% in some cohorts, as well as a significant part of the reasons for emergency room visits.
- Trial name
- MiOx (NCT04925414)
- Testing
- oxygenotherapy
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Headache, Migraine
Intranasal Ketorolac Trial
The purpose of this study is to determine if intranasal (IN) Ketorolac in combination with oral Prochlorperazine and Diphenhydramine is non-inferior to current migraine management which involves use of intravenous (IV) Ketorolac…
- Trial name
- NCT06083571
- Testing
- Ketorolac, Prochlorperazine, Diphenhydramine
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Cervicogenic Headache
Dry Needle In Management of Cervicogenic Headache
Headache is an important health problem. It is the commonest type of all signs of illness in the people worldwide. Cervicogenic Headache is commonest musculoskeletal condition in physiotherapy practice.
- Trial name
- NCT04625387
- Testing
- Dry Needle and Exercise
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Raj Nursing and Paramedical College
Migraine
Efficacy of Manual Therapy for the Treatment of Migraine.
Introduction According to the World Health Organization (WHO) at least 47% of adults have suffered from headache in the last year.
- Trial name
- MT-Migraine (NCT03555214)
- Testing
- Manual Therapy based on soft tissues, Control group, Manual Therapy based on structural techniques
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- University of Valencia
Migraine
Efficacy and Safety Trial of BHV-2100 for the Acute Treatment of Migraine
This study is designed to identify at least one dose of BHV-2100 that is safe and effective in reducing headache pain and other symptoms in the treatment of migraine.
- Trial name
- NCT06603623
- Testing
- BHV-2100
- Where
- 60 sites in United States
- Volunteers
- 647 people
- Sponsor
- Biohaven Therapeutics Ltd.
Cervicogenic Headache
Associations Between Neck Muscle Fatigue, Joint Position Sense, and Headache in Cervicogenic Headache
This research study aims to better understand the relationships between neck muscle function, neck joint position sense, and headache pain and disability in people with chronic cervicogenic headache.
- Trial name
- NCT05972382
- Testing
- Quantitative Sensory and Neurophysiological Testing
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ahram Canadian University
Migraine, Migraine With Aura
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101 in the Acute Treatment of Migraine
Study STS101-002 is a randomized, double-blind, parallel group, placebo-controlled, multicenter study to evaluate the efficacy, safety, and tolerability of single doses of STS101 (dihydroergotamine nasal powder) in the acute…
- Conditions
- Migraine, Migraine With Aura, Migraine Without Aura
- Trial name
- EMERGE (NCT03901482)
- Testing
- Dihydroergotamine
- Where
- 117 sites in United States
- Volunteers
- 1,201 people
- Sponsor
- Satsuma Pharmaceuticals, Inc.
Migraine
Study to Test Rizatriptan in the Early Treatment of Acute Migraine (0462-081)
The purpose of this study is to test the effectiveness of rizatriptan benzoate in the early treatment of an acute migraine attack.
- Trial name
- NCT00516737
- Testing
- Comparator: rizatriptan benzoate
- Volunteers
- 207 people
- Sponsor
- Organon and Co
Migraine
Healthcare Costs and Resource Utilization in Aimovig Migraine Patients: a Retrospective Study Using United States Claims Data
The proposed study is a retrospective, non-interventional analysis that uses medical and pharmacy claims data in the US from Komodo Health
- Trial name
- NCT05177406
- Testing
- Aimovig
- Where
- United States
- Volunteers
- 1,839 people
- Sponsor
- Novartis Pharmaceuticals
Migraine, Tension-type Headache
Comparing Naproxen to Sumatriptan for Emergency Headache Patients
2/3 of patients discharged from an emergency department after treatment for an acute headache will still be bothered by headache within 24 hours of emergency department (ED) treatment.
- Conditions
- Migraine, Tension-type Headache, Primary Headache Disorder
- Trial name
- HEDNet2 (NCT00449787)
- Testing
- Sumatriptan 100 mg, Naproxen
- Where
- 2 sites in United States
- Volunteers
- 401 people
- Sponsor
- Montefiore Medical Center
Migraine
A Phase III Trial of e-TNS for the Acute Treatment of Migraine
The main objective of this study is to have Phase III evidences of the efficacy of the Cefaly® Abortive Program device used at home for 2 hours to treat a migraine attack.
- Trial name
- TEAM (NCT03465904)
- Testing
- Verum Cefaly® Abortive Program device
- Where
- 10 sites in United States
- Volunteers
- 607 people
- Sponsor
- Cefaly Technology
Migraine, Pain
THE EFFECTS OF KINESIO®TAPING IN PATIENTS WITH MIGRAINE
In patients with migraine, neck pain and trigger points in the neck muscles are common in clinical practice. This study was to investigate whether kinesiotaping applied to the cervical muscles has a clinical effect on pressure…
- Trial name
- NCT04185714
- Testing
- Kinesiotaping
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Migraine
A Study to Learn About PRT-064040 Nasal Spray in Healthy Adult Subjects
This trial is a Phase I, single-center, randomized, double-blind, placebo-controlled study conducted in healthy Chinese adult subjects.
- Trial name
- NCT07016516
- Testing
- PRT-064040 nasal spray
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sichuan Purity Pharmaceutical Technology Co., Ltd.
Migraine Headache
A Study of Galcanezumab (LY2951742) in Participants With Migraine Headache
The main purpose of this study is to evaluate whether the study drug known as galcanezumab is safe and effective in the prevention of migraine headaches.
- Trial name
- NCT02163993
- Testing
- Galcanezumab
- Where
- 40 sites in United States
- Volunteers
- 414 people
- Sponsor
- Eli Lilly and Company
Vomiting, Headache
Low Dose Versus Usual Dose Dexamethasone for Symptom Control in Children Undergoing Cranial or Craniospinal Radiation
The purpose of this study is to evaluate the effectiveness of low dose dexamethasone versus high dose dexamethasone in the treatment of radiation induced vomiting.
- Trial name
- NCT01135550
- Testing
- High dose dexamethasone, Low dose dexamethasone
- Where
- 5 sites in Canada
- Volunteers
- 25 people
- Sponsor
- The Hospital for Sick Children
Cluster Headache
Pathway CH S&E Registry
Monitor the safety and performance of the Pulsante Microstimulator System.
- Trial name
- SER (NCT02440776)
- Where
- 9 sites in Denmark, Germany and 3 more
- Volunteers
- 30 people
- Sponsor
- Autonomic Technologies, Inc.
Post-Traumatic Headache
Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 2
Anesthetic greater occipital nerve (GON) blockade is a simple, inexpensive, and safe procedure that has demonstrable headache pain suppressing effects.
- Trial name
- NCT07796074
- Testing
- Bupivacaine bilateral greater occipital nerve block
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Yale University
Headache, Healthy
Multiomics After Headache Provocation of People Who Are Unable to Have Headache
Headaches are extremely common illnesses with a combined lifetime prevalence of 90-99% in Europe. Despite this high prevalence, there are persons who have never, in their whole life, encountered a headache.
- Trial name
- NCT04218760
- Testing
- Isosorbide Mononitrate 60 MG Extended Release Oral Tablet [Imdur], Blood sample
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Danish Headache Center
Headache, Migraine
Hemodynamic and Headache-Inducing Effect of Intravenous Vasoactive Intestinal Peptide in Migraineurs
We hypothesized that infusion of VIP may induce headache/migraine in migraineurs and that VIP-induced headache may be associated with dilation of intra- and extracranial vessels.
- Conditions
- Headache, Migraine, Vasoactive Intestinal Peptide, Ultrasonography, Doppler, Transcranial
- Trial name
- NCT00272896
- Testing
- Vasoactive intestinal peptide
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Danish Headache Center
Headache, Comorbidities
Headache Registration and Followup Initiated by Tongji Hospital, HUST
Headache is one of the most common chief complaints in clinical practice, with a high global prevalence rate. It may originate from a primary headache disorder or manifest as a clinical symptom of various diseases due to the…
- Trial name
- HEALTH (NCT07269561)
- Where
- China
- Volunteers
- 50,000 people
- Sponsor
- Tongji Hospital
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