Clinical trials: Cephalalgia
Chronic Migraine
A Study to Evaluate the Tolerability of Botox and Topiramate or Botox and Placebo and Effect on Cognitive Efficiency
The purpose of this study is to evaluate sustained tolerability, quality of life, and change in cognitive efficiency following treatment with OnabotulinumtoxinA and daily topiramate vs.
- Trial name
- NCT01700387
- Testing
- onabotulinumtoxinA, Topiramate
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cady, Roger, M.D.
Migraine
Trial on Metoclopramide and Ketoprofen in Acute Migraine of Childhood
This is a Randomized double blind trial with the aim to estimate the effectiveness of 3 therapeutic regimes per os on migraine pain: metoclopramide 0,15 mg/kg + placebo metoclopramide 0,15 mg/Kg + ketoprofen 1 mg/kg ketoprofen 1…
- Trial name
- NCT00557544
- Testing
- metoclopramide, ketoprofen
- Where
- Italy
- Sponsor
- IRCCS Burlo Garofolo
Migraine, Migraine Disorder
Tai Chi and Acupuncture on Migraine Attack Prevention and Brain White Matter Changes
The goal of this clinical trial is to determine the effectiveness of Tai Chi training and acupuncture on the migraine attacks and structural brain changes in women with episodic migraine.
- Trial name
- NCT06967909
- Testing
- Tai Chi training, Acupuncture
- Where
- Hong Kong
- Volunteers
- 132 people
- Sponsor
- The Hong Kong Polytechnic University
Migraine
Comparison of Patient-reported Outcomes for Rimegepant and Triptans in the 2023 US National Health and Wellness Survey
This is a cross-sectional study using the cross-sectional 2023 National Health and Wellness Survey (NHWS) data from the US, with a large and nationally representative population (N=75,007).
- Trial name
- NCT06680206
- Testing
- Rimegepant, Triptans
- Where
- United States
- Volunteers
- 1,395 people
- Sponsor
- Pfizer
Migraine
Observational Study on the Efficacy, Safety, and Tolerability of GAlcanezumab in Real Life Migraine Patients in ITaly
Objective: To determine in real life the efficacy, safety and tolerability of galcanezumab in the prevention of high-frequency episodic migraine (HFEM) and chronic (CM) migraine.
- Trial name
- GARLIT (NCT04803513)
- Testing
- Galcanezumab
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Campus Bio-Medico University
Chronic Migraine, Headache
Efficacy of GONB in Patients of Migraine
The study was carried to determine the analgesic efficacy of greater occipital nerve block in patients of migraine. It was a randomised controlled which took place from april 2022 - october 2022.
- Trial name
- NCT05679765
- Testing
- Greater Occipital Nerve Block with dexamethasone and lidocaine, Greater Occipital Nerve Block with 0.9% saline
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Pain Medicine Department
Migraine Headache, Oxygen
Oxygen in Migraine Treatment
IIn this study, the investigators planned to investigate effectiveness of supplemental oxygen in patients (18-65 years) who were diagnosed as headache related to migraine without aura in the emergency department (ED).
- Trial name
- NCT05780671
- Testing
- oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- Ankara Ataturk Sanatorium Training and Research Hospital
Visual Snow Syndrome, Migraine
Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli
The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: Does VSS arise from spontaneous activity in brain pathways?…
- Conditions
- Visual Snow Syndrome, Migraine, Healthy
- Trial name
- VPVSS (NCT06961864)
- Testing
- Visual Adaptation, Assessments and Questionnaires, Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Migraine
Dexamethasone for Migraine - Dose Comparison
Dexamethasone is an evidence-based treatment of acute migraine. This is a randomized comparison of two different doses of dexamethasone for acute migraine. All patients will also be treated with metoclopramide.
- Trial name
- NCT04112823
- Testing
- Dexamethasone 4mg, Dexamethasone 16mg
- Where
- United States
- Volunteers
- 209 people
- Sponsor
- Montefiore Medical Center
Migraine Without Aura, Migraine With Aura
Evaluation of a Novel Device for Treatment of Migraine Headache
Migraine is a common neurologic with attacks of headache and associated symptoms such as nausea, vomiting, phono and photophobia. Migraine can lead to substantial functional impairment.
- Trial name
- NCT03361423
- Testing
- Nerivio Migra-1 active device
- Where
- 12 sites in United States, Israel
- Volunteers
- 296 people
- Sponsor
- Theranica
CVA
CVA in Patients Suffering From Decreased Consciousness, Confusion or Headaches to an Emergency Room
A CVA occurs when there is a sudden interruption of blood supply to the brain. Fast identification of CVA is crucial in order to refer the patient to an appropriate medical center as well as to direct him/her to a suitable…
- Trial name
- NCT03377062
- Testing
- EEG monitoring
- Where
- Israel
- Volunteers
- 120 people
- Sponsor
- Rambam Health Care Campus
Migraine, Headache
Narrow Band Green Light and Migraine
Study volunteers are asked to use the Allay Lamp routinely during the 6-week study period. A web based survey is provided when the Lamp is purchased for study volunteers to complete.
- Trial name
- NCT04841083
- Testing
- Allay Lamp
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- Vedanta Research
Cervicogenic Headache
Comparative Effects of Dynamic Cupping and Facilitated Positional Release in Cervicogenic Headache
Cervicogenic headache (CGH) is a secondary headache disorder originating from structural and functional impairments of the cervical spine, accounting for approximately 15-20% of all chronic headaches worldwide.
- Trial name
- NCT07911254
- Testing
- Dynamic Cupping, Facilitated Positional Release technique
- Where
- Pakistan
- Volunteers
- 41 people
- Sponsor
- University of Management and Technology Lahore
Migraine
Nutritional Intervention in Migraine
Migraine is a common medical condition. Several studies suggest that obesity and/or weight gain are risk factors for aggravating migraine course, especially increase the frequency of headache episodes.
- Trial name
- NCT02703129
- Testing
- Nutritional intervention
- Where
- Brazil
- Volunteers
- 52 people
- Sponsor
- Federal University of Minas Gerais
Post-Lumbar Puncture Headache
Epidural Blood Patch on the Resolution of Postdural Puncture Headache (PDPH)
The purpose of this study is to address the question, "What is the volume of blood for injection at epidural blood patch that most effectively relieves post-dural puncture headache?"
- Trial name
- NCT00373074
- Testing
- Epidural Blood Patch
- Where
- United States
- Sponsor
- The University of Texas Health Science Center, Houston
Migraine, Headache
RELAXaHEAD for Headache Patients (Phase II)
The goal of this research is to assess the utility of smartphone-based progressive muscle relaxation (PMR) for the treatment of migraine and sleep.
- Conditions
- Migraine, Headache, Multiple Sclerosis, Insomnia
- Trial name
- NCT05466682
- Testing
- Smartphone-Based Progressive Muscle Relaxation Therapy (PMR), Monitored Usual Care (MUC)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Acute Migraine
Safety and Efficacy Trial of BHV3000 (Rimegepant) 75 mg for the Acute Treatment of Migraine
This trial is to determine whether BHV3000 (rimegepant) 75mg is safe and effictive as a treatment for acute migraine in Chinese and Korean patients
- Trial name
- NCT04574362
- Testing
- Rimegepant
- Where
- 90 sites in China, South Korea
- Volunteers
- 1,648 people
- Sponsor
- Pfizer
Idiopathic Intracranial Hypertension
Surgical Idiopathic Intracranial Hypertension Treatment Trial
Randomized trial of adults (≥18 years old) with idiopathic intracranial hypertension and moderate to severe visual loss without substantial recent treatment who are randomly assigned to (1) medical therapy, (2) medical therapy…
- Trial name
- SIGHT (NCT03501966)
- Testing
- Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting
- Where
- 36 sites in United States, Canada and 1 more
- Volunteers
- 7 people
- Sponsor
- Jaeb Center for Health Research
Cluster Headache
Psilocybin for the Treatment of Cluster Headache
The purpose of this study is to investigate the effects of an oral psilocybin pulse regimen in cluster headache. Subjects will be randomized to receive oral placebo, low dose psilocybin, or high dose psilocybin in three…
- Trial name
- NCT02981173
- Testing
- 0.143 mg/kg Psilocybin or 10 mg Psilocybin, 0.0143 mg/kg Psilocybin or 1 mg Psilocybin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Yale University
Migraine
Validity and Reliability of the Greek WPAI:Migraine
Migraine is a common neurological disorder that can substantially impair work productivity and daily functioning through both absenteeism and presenteeism.
- Trial name
- NCT07847554
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- National and Kapodistrian University of Athens
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