Clinical trials: Cephalalgia
Cervicogenic Headache
Suboccipital Muscle Inhibition Technique vs Rocabado Exercises on Cervicogenic Headache
The purpose of the study is to explore the effectiveness of Suboccipital muscle inhibition technique vs Rocabado exercises on cervicogenic headache.
- Trial name
- NCT06938256
- Testing
- Suboccipital Muscle Inhibition, Rocabado 6x6 Exercises
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Headache, Migraine
Efficacy of Haloperidol vs. Metoclopramide for Treatment of Acute Headaches and Migraines in the Emergency Department
Metoclopramide (Reglan) is a common agent used for relief of headaches in the emergency department (ED).In this study the investigators seek to explore another option for treatment of headaches in the ED, one that may be more…
- Trial name
- NCT02972502
- Testing
- Metoclopramide, Haloperidol, Normal Saline
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- OhioHealth
Headache
Management of Headache Disorders: A Clinical Trial Screening for Prognostic Patient Characteristics
The management of headache disorders is too often based upon trial and error or on personal beliefs and opinions. Seldom it is based on scientific arguments.
- Trial name
- NCT00298142
- Testing
- Usual Care provided by a medical doctor (GP or Neurologist), Usual care plus Physio-/ Manual Therapy
- Where
- 14 sites in Belgium
- Volunteers
- 120 people
- Sponsor
- Vrije Universiteit Brussel
Reversible Cerebral Vasoconstriction Syndrome
Triggers And Risk Factors to Develop a Reversible Cerebral Vasoconstriction Syndrome
This study will be the first to evaluate the role played by potential precipitating factors and risk factors in Reversible Cerebral Vasoconstriction Syndrome (RCVS) through of prospective selection of carefully characterised…
- Trial name
- TARDIS (NCT04179383)
- Testing
- Constitution of a biobank
- Where
- France
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Migraine Headaches
Theramine® in the Prevention of Migraine Headache
The purpose of this study is to evaluate the efficacy of Theramine® as a preventative for migraine headaches.
- Trial name
- NCT01944059
- Testing
- Theramine (medical food/old drug)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Vincent Martin, MD
Spectrum of Altitude-associated Neurologic Forms of Altitude
NSAID RCT for Prevention of Altitude Sickness
The proposed study is a prospective, randomized, double-blind, placebo-controlled clinical trial evaluating ibuprofen and placebo for the prevention of neurological forms of altitude illness [including high altitude headache…
- Trial name
- NCT01606527
- Testing
- Ibuprofen 600mg orally three times daily
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Naval Health Research Center
Migraine, Brain Diseases
Selective Activation of the Adrenomedullin Receptors in Migraine
Adrenomedullin is a neuropeptide implicated in the pathogenesis of migraine. This study investigates whether its administration, after pre-treatment with erenumab (a CGRP-receptor blocking monoclonal antibody), can trigger…
- Conditions
- Migraine, Brain Diseases, Central Nervous System Diseases, Adrenomedullin
- Trial name
- NCT07451769
- Testing
- Adrenomedullin
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- Danish Headache Center
Migraine, Chronic Migraine
Cervical Repositioning Error in Chronic Migraine
This study examines cervical joint position sense in individuals with chronic migraine vs. healthy controls. The ability to reposition the cervical spine after active movement will be evaluated in different head positions.
- Trial name
- NCT05933590
- Testing
- Cervical Joint Repositioning Error Assessment
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ahram Canadian University
Post-Traumatic Headache, Mild Traumatic Brain Injury
Efficacy and Tolerability of Erenumab in the Prophylactic Treatment of Persistent Post-Traumatic Headache
An exploratory open-label study of PPTH patients to study the efficacy and tolerability of erenumab in the prophylactic treatment of persistent headache attributed to mild traumatic injury to the head.
- Conditions
- Post-Traumatic Headache, Mild Traumatic Brain Injury, Post-Concussion Syndrome
- Trial name
- NCT03974360
- Testing
- AMG 334
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Danish Headache Center
Cervicogenic Headache
Effect of Instrument-Assisted Soft Tissue Mobilization on Proprioception and Disability in Patients With Cervicogenic Headache
This study will be conducted to investigate the effect of instrument assisted soft tissue mobilization technique In pain intensity, frequency of headache, medication Uptake, Suboccipital movement in flexion and extension, rounded…
- Trial name
- IASTM (NCT05545423)
- Testing
- instrumented assisted soft tissue mobilization, traditional therapy
- Volunteers
- 80 people
- Sponsor
- Cairo University
Migraine, Chronic Migraine, Headache
A Study Investigating the Efficacy of GON Blocks.
Greater occipital nerve block ("GON block") is carried out extensively in the treatment of chronic migraine, but more research is required to understand the effectiveness of the procedure.
- Trial name
- NCT04017741
- Testing
- Combined Depo-Medrone and Lidocaine, Sodium Chloride 0.9% Inj
- Where
- United Kingdom
- Volunteers
- 8 people
- Sponsor
- Barts & The London NHS Trust
Migraine Associated Vertigo, Tinnitus
Comparing Migraine Preventive Therapies vs. Anti-CGRP Therapies for Tinnitus in Patients With Migraine (COMPACT-PM)
Many people with migraine also experience tinnitus - a persistent ringing, buzzing, or hissing in the ears - and research suggests these conditions share underlying biological mechanisms, including a protein called calcitonin…
- Conditions
- Migraine Associated Vertigo, Tinnitus, Migraine, Vestibular Migraine
- Trial name
- COMPACT-PM (NCT07655440)
- Testing
- Galcanezumab, Erenumab 70 mg, Eptinezumab
- Volunteers
- 120 people
- Sponsor
- Stanford University
Neurasthenia, Chronic Pain
Effectiveness of Mind-Body Interventions for Frequent Attendees Suffering From Medically Unexplained Symptoms (MUS)
The purpose of this study is to check the medical efficacy and economic benefits of multidisciplinary care in patients with unexplained medical complaints and consume medical services frequently.
- Conditions
- Neurasthenia, Chronic Pain, Chronic Headache
- Trial name
- NCT02141568
- Testing
- Medical and Psychological treatment
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Soroka University Medical Center
Post-Traumatic Headache
Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache
The aim is to investigate whether opening of large conductance calcium-activated potassium (BKCa) channels induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild…
- Trial name
- NCT05378074
- Testing
- Maxipost
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Migraine
Migraine Characteristics and Associated Factors
This cross-sectional study aims to evaluate the clinical characteristics of migraine and factors associated with migraine-related disability and impact in adults diagnosed with primary migraine.
- Trial name
- NCT07822386
- Testing
- Observational assessment
- Volunteers
- 100 people
- Sponsor
- Lokman Hekim University
Tension-Type Headache
Manual Therapy in Tension-type Headache
Tension-type headache (TTH) causes a significant negative impact on working and daily life due to the reduction in work productivity and family and social activities causes.
- Trial name
- NCT04546165
- Testing
- manipulation plus exercise, suboccipital inhibition plus exercise, exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Headache Disorders
Acupuncture for the Treatment of Chronic Daily Headaches
The purpose of this study is to determine whether acupuncture can reduce pain in long-term headache sufferers.
- Trial name
- NCT00086021
- Testing
- Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 74 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Migraine, Caffeine Withdrawal
The Effects of Caffeine Withdrawal on Migraine
Sporadic and chronic dietary consumption of caffeine has substantial biological effects on the nervous system. The effects on migraine are at large not known.
- Trial name
- NCT03022838
- Testing
- Caffeine
- Where
- 3 sites in Norway
- Volunteers
- 10 people
- Sponsor
- Nordlandssykehuset HF
Sport-related Concussion
Effects of Physiotherapy in Individuals With Persistent Symptoms Following Concussion
The purpose of this study is to determine the effects of a combined physiotherapy treatment (including vestibular rehabilitation and treatment for the cervical spine) in youth and young adults with ongoing symptoms of dizziness…
- Trial name
- PTConc (NCT01860755)
- Testing
- Control postural education, general range of motion and strengthening in addition to the standard of care, Physiotherapy
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Sport Injury Prevention Research Centre
Tension Headache
Suboccipital Inhibition in Tension Headache
The researchers will carry out a randomized experimental study. Participants in the experimental group will receive a treatment based on suboccipital inhibition technique in addition to conventional treatment.
- Trial name
- NCT04376125
- Testing
- Suboccipital inhibition in tension headache
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad de León
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