Clinical trials: Cephalalgia
Migraine
ZAP, US. Zomig for Appropriate for Primary Care
The purpose of this study is to determine how useful and effective the use of ZOMIG-ZMT™ (zolmitriptan) 5.0 mg and ZOMIG® Nasal Spray (zolmitriptan) 5.0 mg is for patients, in treating migraine over a period of 6 months
- Trial name
- NCT00637286
- Testing
- Zolmitriptan
- Volunteers
- 120 people
- Sponsor
- AstraZeneca
Migraine
Melatonin for Adolescent Migraine Prevention Study
This will be a randomized, multi-site double-blind placebo-controlled trial of melatonin (2 different dosing arms) vs. placebo for migraine prevention in adolescents.
- Trial name
- MAP (NCT03150797)
- Testing
- Melatonin
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- Amy Gelfand
Gulf War Illness, Headache
Machine Learning in Guiding rTMS Treatment for GWI-Related Headaches and Body Pain
The goal of this clinical trial is to create a machine learning algorithm to improve active repetitive transcranial magnetic stimulation (rTMS) treatments for veterans and/or active military personnel by alleviating Gulf War…
- Conditions
- Gulf War Illness, Headache, Muscle and Joint Pain
- Trial name
- SVM - GWI (NCT07325513)
- Testing
- Active Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Veterans Medical Research Foundation
Migraine Disorders
Efficacy of Pregabalin in Migraine Prevention
The purpose of this study is to evaluate the efficacy and safety of pregabalin in comparison with sodium valproate in migraine prevention with a randomized blinded crossover study.
- Trial name
- NCT00447369
- Testing
- Pregabalin, sodium valproate
- Where
- Chile
- Volunteers
- 70 people
- Sponsor
- Hospital Militar del General Luis Felipe Brieba Aran
Headache, Persistent Idiopathic Facial Pain
Transnasal Versus Suprazygomatic SPG Block in Persistant Idiopathic Facial Pain
The International Headache Society defines persistent idiopathic facial pain (PIFP) as persistent facial pain that does not have the characteristics of cranial neuralgia, is blunt, persistent, persistent, bothersome and not…
- Trial name
- NCT06496841
- Testing
- Transnasal Sphenopalatine ganglion block, Ultrasound-guided suprazygomatic sphenopalatine ganglion block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Diskapi Teaching and Research Hospital
Head Neck Cancer, Radiation Neuropathy
Study of Efficacy and Safety of Gabapentin to Reduce the Need for Strong Opioid Use in Head and Neck Cancer Patients.
A multi-centre, double-blind, randomized-controlled trial to study the efficacy and safety of gabapentin to reduce the need for strong opioid use in the treatment of radiation-induced pain in head and neck cancer (HNCA) patients…
- Conditions
- Head Neck Cancer, Radiation Neuropathy, Pain, Neuropathic
- Trial name
- stREnGTH (NCT03747562)
- Testing
- Gabapentin
- Where
- 2 sites in Belgium
- Sponsor
- University Hospital, Ghent
Cervicogenic Headache
Effects of Garston Tool and Neuromuscular Reeducation in Cervical Headache
Patients suffering from Cervicogenic headache have restricted range of motion and pain which in turn causes functional disability and reduced quality of life.
- Trial name
- NCT05849545
- Testing
- Garston tool, Neuromuscular Re-education
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Health Education Research Foundation (HERF)
Migraine
A Research Study of Greater Occipital Nerve Block as a Treatment for Acute Migraine Attacks
Several observational studies have shown improvement in episodic migraine with the use of greater occipital nerve block as an acute therapy, and a recent placebo controlled trial did not show a decrease in frequency of episodic…
- Trial name
- NCT03159000
- Testing
- Saline, lidocaine/bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Binocular Vision Disorder, Convergence Insufficiency
Neurolens Headache Study
To understand the benefits of the neurolens Measurement Device and neurolens treatment as it pertains to treating symptoms related to Chronic Headaches.
- Conditions
- Binocular Vision Disorder, Convergence Insufficiency, Headache, Computer Vision Syndrome
- Trial name
- NCT05070767
- Testing
- Neurolens spectacle lens
- Where
- 10 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Neurolens Inc.
Migraine
A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Participants 6 to 17 Years of Age
The primary objective of the study is to evaluate the effectiveness of fremanezumab as compared to placebo for the preventive treatment of chronic migraine (CM).
- Trial name
- NCT04464707
- Testing
- Fremanezumab
- Where
- 89 sites in United States, Canada and 7 more
- Volunteers
- 292 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Migraine Disorders
The Association Among Headache Severity, Head Posture, Cervical Muscle Endurance, and Neck Disorders in Individuals With Migraine
To determine the relationship among headache severity, head posture, cervical muscle endurance and neck disorders in individuals with migraine.
- Trial name
- NCT05797012
- Testing
- To assess headache severity, head posture, cervical muscle endurance and neck disorders.
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Tokat Gaziosmanpasa University
Migraine Disorders
Sustained onabotulinumtoxinA Therapeutic Benefits in Patients With Chronic Migraine
To assess whether there is a sustained benefit and good safety with repeated onabotulinumtoxinA sessions in chronic migraine over more than three years of treatment.
- Trial name
- NCT03606356
- Testing
- Onabotulinum toxin A
- Volunteers
- 56 people
- Sponsor
- Corfu Headache Clinic
Episodic Migraine, Prophylaxis
The Role of Left Prefrontal Transcranial Magnetic Stimulation in Episodic Migraine Prophylaxis
The aim of the study was to examine the prophylactic role of repetitive transcranial magnetic stimulation (rTMS) on the frequency, and severity of migraine attacks in episodic migraineurs who failed medical treatment.
- Trial name
- NCT04031781
- Testing
- repetitive transcranial magnetic stimulation (rTMS) 100% motor threshold, repetitive transcranial magnetic stimulation (rTMS) 50% motor threshold
- Volunteers
- 33 people
- Sponsor
- Ain Shams University
Cluster Headache
Data Collection on the ATI Neurostimulation System: SPG Stimulation for Cluster Headache
The primary objectives of the Registry are to: 1. Monitor the transfer of the ATI Neurostimulation System and its safety/clinical performance to a larger number of centers in the post market phase and 2.
- Trial name
- NCT01677026
- Where
- 11 sites in Denmark, Germany
- Volunteers
- 150 people
- Sponsor
- Autonomic Technologies, Inc.
Migraine
Does tDCS is Effective in the Prophylactic Treatment of Migraine
Migraine has been described as one of the most common neurological diseases, with high social and economic impact. Despite the high prevalence, the pathophysiology of migraine is still unknown, several studies have been developed…
- Trial name
- NCT01886274
- Testing
- Transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Headache, Migraine
Study of Intramuscular Ropivacaine Injections for Treatment of Pediatric Headache
Objective: To determine if lower paracervical intramuscular ropivacaine injection is an effective treatment for pediatric headache in an emergency department setting.
- Trial name
- NCT00680823
- Testing
- Ropivacaine, Normal saline
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Robert Hickey
Obesity, Epidural; Anesthesia, Headache
Evaluation of Sagittal Abdominal Diameter as a Predictor of the Skin to Epidural Space Distance in Obese Patients
The aim of this study is to evaluate the use of the sagittal abdominal diameter (SAD) as a potential predictor of the skin to epidural space distance (SESD) and to compare its accuracy versus that of the BMI as a previously…
- Trial name
- NCT04095117
- Testing
- Epidural block
- Where
- 2 sites in Egypt
- Volunteers
- 135 people
- Sponsor
- Ain Shams University
Migraine
Randomized Trial in Adult Participants With Acute Migraines
The purpose of this study is to test the safety and efficacy of BHV-3500 (zavegepant) versus placebo in the acute treatment of moderate or severe migraine.
- Trial name
- NCT04571060
- Testing
- Zavegepant
- Where
- 94 sites in United States
- Volunteers
- 1,978 people
- Sponsor
- Pfizer
Concussion, mTBI
Neurofeedback Impact on Veterans With mTBI
This study will evaluate neurofeedback (NFB) training as a low risk, non-invasive, effective treatment for Veterans diagnosed with mild traumatic brain injury (mTBI) and experiencing chronic post-concussive symptoms (PCSs).
- Conditions
- Concussion, mTBI, Post-Concussive Symptoms, Chronic Headache
- Trial name
- NFBVETmTBI (NCT04195685)
- Testing
- Neurofeedback (NFB)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- VA Office of Research and Development
Migraine
The Combined Effects of omega3 Fatty Acids and Curcumin Supplementation on Inflammatory and Endothelial Factors in Migraine Patients
The aim of this study is to determine the effects of omega 3 fatty acid, curcumin and their combination or placebo for 2 months on the gene expression of COX-2, iNOS, TNF-α, IL-1β, IL-6, VCAM-1 and ICAM-1 in the peripheral blood…
- Trial name
- NCT02532023
- Testing
- omega 3 fatty acid, curcumin
- Volunteers
- 80 people
- Sponsor
- Tehran University of Medical Sciences
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