Clinical trials: Cephalalgia
Migraine in Adults
EXErcise in MIGraine
The study project aims to implement therapeutic patient education for migraine, promoting improvement in outpatient clinical practice by providing counseling moments specifically dedicated to known health risk factors (sedentary…
- Trial name
- EXEMIG/01 (NCT07508449)
- Testing
- exercise program supervised by specialized kinesiologists, Standard neurological visit at the Headache Centre
- Where
- 2 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Centro Universitario Ricerca Interdipartimentale Attivita' Motoria
Migraine
Safety and Efficacy of Oral Idebenone for Preventive Treatment of Migraine in Adult Migraine Patients
This is a multi-center, prospective, double-blind randomized controlled trial on a sample of patients with migraine. Subjects will only be enrolled when a physician or research assistant who is familiar with the study protocol is…
- Trial name
- NCT05411978
- Testing
- Idebenone
- Where
- China
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Migraine
A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Participants 6 to 17 Years of Age
The primary objective of the study is to evaluate the effectiveness of fremanezumab as compared to placebo for the preventive treatment of chronic migraine (CM).
- Trial name
- NCT04464707
- Testing
- Fremanezumab
- Where
- 89 sites in United States, Canada and 7 more
- Volunteers
- 292 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Migraine With Aura, Migraine Without Aura
Is Chiropractic Spinal Manipulative Therapy an Efficient Treatment Option for Migraine
This study will highlight and validate chiropractic spinal manipulative therapy (CSMT) for migraine. If the method proves to be effective, it will provide a new non-pharmacological treatment option for migraine.
- Trial name
- NCT01741714
- Testing
- Chiropractic spinal manipulative therapy
- Where
- Norway
- Volunteers
- 104 people
- Sponsor
- University Hospital, Akershus
Migraine
Mindfulness and Mechanisms of Pain Processing in Adults With Migraines
Although many adults with migraines use non-pharmacological treatment options, there is a lack of research on the use of many mind/body techniques specifically for headache.
- Trial name
- NCT02695498
- Testing
- Mindfulness Based Stress Reduction, Migraine/stress Education
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Wake Forest University Health Sciences
Headache, Post-Concussion Syndrome
The Effectiveness of Osteopathic Manipulative Medicine in the Management of Headaches Associated With Post Concussion Syndrome
Pilot study looking at the Osteopathic Manipulative Treatment (OMT) for various headache types in patients with post-concussion syndrome (PCS).
- Trial name
- NCT04732338
- Testing
- Osteopathic Manipulative Therapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hackensack Meridian Health
Migraine Without Aura, Acupuncture Therapy
Brain Connectome for Acupuncture-treated Migraine Patients
Acupuncture has been a means of treating headaches and migraine since 2002 and is now a World Health Organisation-recognized prophylactic treatment for migraine.
- Trial name
- ACU-BRAIN (NCT04157192)
- Testing
- Real acupuncture
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Anesthesia, Safety Issues
Sonographic Predictors of Difficult Epidural Placement.
Epidural placement is a commonly used procedure for pain management during labor, delivery, and surgeries. However, epidural placement is often considered a technically challenging and complex procedure that requires a high level…
- Conditions
- Anesthesia, Safety Issues, Epidural; Anesthesia, Headache
- Trial name
- PREC-EPI (NCT05893264)
- Testing
- Data collection
- Where
- Italy
- Sponsor
- University of Padova
Migraine With Aura, Migraine Without Aura
Maxalt 10mg Plus Caffeine 75mg in the Acute Treatment of Migraine Headache
The purpose of this study is to evaluate the effect of rizatriptan, alone or combined with caffeine for treating acute attacks of migraine. Each subject will have 3 months to treat 3 acute migraine headache attacks.
- Trial name
- NCT00471952
- Testing
- Maxalt 10mg MLT plus Caffeine 75mg
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Diamond Headache Clinic
Migraine With Aura
Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura
The following study is being conducted to explore the safety and effectiveness of a new chemical entity called NXN-188 in subjects with a history of migraine with aura.
- Trial name
- NCT00877838
- Testing
- NXN-188
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Danish Headache Center
Stent Stenosis, Intracranial Hypertension
Endovascular Stenting Treatment for Patients With Internal Jugular Vein Stenosis
This is a prospective, randomized, single-center clinical study aiming to explore the safety and efficacy of venous stenting for patients with internal jugular vein stenosis (IJVS).
- Conditions
- Stent Stenosis, Intracranial Hypertension, Headache, Tinnitus
- Trial name
- NCT03373292
- Testing
- Venous stenting for internal jugular vein stenosis, One-month routine medical treatment followed by venous stenting for internal jugular vein stenosis
- Volunteers
- 60 people
- Sponsor
- Capital Medical University
Headache, Cephalgia
Effect of Osteopathic Manipulative Treatment for Patients With Chronic Headache
Participants with chronic or recurrent headache, unrelated to any known pathology or disease, will be randomly assigned to one of four interventions: Osteopathic manipulation of the body other than the head, osteopathic…
- Conditions
- Headache, Cephalgia, Migraine
- Trial name
- OMTHA (NCT01332864)
- Testing
- Osteopathic Manipulative Treatment (OMT), Light touch
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Western University of Health Sciences
Migraine Disorder, Low Back Pain
Sleep Hygiene Education to Improve Sleep in Chronic Migraine and Back Pain
The goal of this clinical trial is to learn whether sleep hygiene education can improve sleep quality and reduce pain in adults with migraine and/or chronic lower back pain.
- Conditions
- Migraine Disorder, Low Back Pain, Chronic Pain, Sleep Disorder (Disorder)
- Trial name
- NCT07425964
- Testing
- Sleep Hygiene Education
- Volunteers
- 100 people
- Sponsor
- Aalborg University
Insomnia, Migraine
Treatment of Insomnia in Migraineurs
It is hypothesized that treating insomnia in migraineurs, many of whom also have tension headaches, prolongs total sleep time to the extent that it decreases overall headache frequency.
- Trial name
- NCT00812214
- Testing
- eszopiclone
- Volunteers
- 113 people
- Sponsor
- MedVadis Research Corporation
Migraine Disorder
An Open Label Trial of ALD403 (Eptinezumab) in Chronic Migraine
An evaluation of long term safety of repeat ALD403 doses in Chronic Migraine
- Trial name
- PREVAIL (NCT02985398)
- Testing
- ALD403 (Eptinezumab)
- Where
- 20 sites in United States
- Volunteers
- 128 people
- Sponsor
- Alder Biopharmaceuticals, Inc.
Headache, Migraine
Study on Indomethacin-responsive Headaches
Description of modalities concerning the patient care of headaches sensible to indometacine.
- Trial name
- NCT03967483
- Testing
- Indometacin
- Volunteers
- 100 people
- Sponsor
- Anne Ducros
Temporomandibular Dysfunction
Temporomandibular Joint Dysfunction in Patients With Traumatic Brain Injury
Trauma, neurological disorders and psychological problems, which are the etiological factors of temporomandibular joint dysfunction, can be seen in patients with traumatic brain injury.
- Trial name
- NCT05572541
- Testing
- Fonseca questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Migraine
Magnetic Therapy in Migraine Prophylaxis
Background: The therapy with pulsed electromagnetic fields (PEFs) has been used as a therapeutic modality for at least 40 years. However, their effect in the migraine prophylaxis is unclear.
- Trial name
- NCT00901862
- Testing
- Pulsed magnetic fields (Quantum MH-2MR bracelet)
- Where
- Mexico
- Volunteers
- 19 people
- Sponsor
- El Instituto Nacional de Neurologia y Neurocirugia Manuel Velasco Suarez
Headache Disorders, Primary, Headache Disorders
Amylin-Induced Migraine Attacks Without Aura
Pramlintide is a peptide analogue of human amylin which is a vasoactive signaling molecule involved in the pathogenesis of migraine.
- Conditions
- Headache Disorders, Primary, Headache Disorders, Brain Diseases, Nervous System Diseases
- Trial name
- NCT07340788
- Testing
- Amylin
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Danish Headache Center
Migraine
Effects of Prayer on Pain Thresholds and Scores of Anxiety and Depression in Participants With and Without Migraine
This study comprised two separate assessor-blinded randomized crossover experiments, one in participants with migraine and one in participants without migraine.
- Trial name
- NCT07143461
- Testing
- Prayer Condition, Reading Condition
- Where
- Brazil
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
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