Clinical trials: Cerebral Aneurysm Unruptured
Cerebral Aneurysm Unruptured, Cerebral Aneurysm Ruptured
Surgical Theater's Surgery Rehearsal Platform
Objectives: The objective of this clinical study is to determine if the use of the SRP will lead to improved effort and time efficiency in cerebral aneurysm surgery.
- Trial name
- SRP (NCT02099318)
- Testing
- Active SRP cases, Control cases
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Intracranial Aneurysm
Contour Neurovascular System - European Pre-Market Unruptured Aneurysm
Cerus Endovascular is sponsoring a prospective, multi-center trial to document the safety and performance of the Contour Neurovascular System™ ("Contour").
- Trial name
- CERUS (NCT03680742)
- Testing
- Contour Neurovascular System
- Where
- 6 sites in Austria, Denmark and 1 more
- Volunteers
- 34 people
- Sponsor
- Cerus Endovascular, Inc.
Aneurysm Cerebral
Study to Evaluate the TUBE Device Ability to Treat Unruptured, Wide-neck or Fusiform Aneurysms
To assess the safety and performance of the TUBE device in the endovascular treatment of unruptured, wide-neck or fusiform intracranial aneurysms located on the internal carotid artery (ICA) or its branches
- Trial name
- NV01 (NCT07079956)
- Testing
- TUBE Flow Diverter
- Where
- 3 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- NVMedTech
Aneurysm Cerebral (Unruptured)
Multimodal Approach Feasability Study for Untreated and Unruptured Intracranial Aneurysms
This feasibility study aims to evaluate the SYLVER system's ability to visualize intracranial aneurysms in accordance with 3D rotational angiography (3DRA) as the reference technique.
- Trial name
- miniCAN (NCT07864389)
- Testing
- 3D CEUS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Resolve Stroke
Unruptured Intracranial Aneurysm, Cerebral Aneurysm Unruptured
Comparison of Propofol and Propofol-Ketamine Anesthesia on Optic Nerve Sheath Diameter in Endovascular Cerebral Aneurysm Procedures
This study aimed to compare the effects of propofol-based anesthesia and propofol-ketamine anesthesia on optic nerve sheath diameter (ONSD) in patients undergoing elective endovascular treatment of unruptured intracranial…
- Conditions
- Unruptured Intracranial Aneurysm, Cerebral Aneurysm Unruptured, Cerebral Aneurysms
- Trial name
- ONSD-KP (NCT07542015)
- Testing
- Propofol (Astra-Zeneca), Propofol and Ketamine Mixture (Ketofol)
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Ankara City Hospital Bilkent
Cerebral Aneurysm Unruptured
Development Platform Construction and Application Promotion of Drug-Eluting Stents for Intracranial Aneurysm Interventional Therapy
This study is a post-marketing clinical study of the Lattice Flow-Diverting Dense-Mesh Stent. It plans to enroll 280 patients, who will be treated for unruptured intracranial aneurysms using the Lattice Flow-Diverting Dense-Mesh…
- Trial name
- NCT07190781
- Testing
- Flow-Diverting Dense-Mesh Stent
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Xinjian Yang
Aneurysm Cerebral, Bifurcation
LUMENS-1 Canada Early Feasibility Study Clinical Investigation Plan
The primary objective of this clinical investigation is to evaluate the early safety and feasibility of the LuSeed Aneurysm Embolization System for treating unruptured intracranial aneurysms (IA).
- Conditions
- Aneurysm Cerebral, Bifurcation, Unruptured Intracranial Aneurysm, Saccular Aneurysm
- Trial name
- NCT07259018
- Testing
- LuSeed Aneurysm Embolization System
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- LuSeed Vascular LTD.
Unruptured Intracranial Aneurysm
Unruptured Cerebral Aneurysm: Prediction of Evolution
The protocol has many assets. A prospective nationwide recruitment allows for the inclusion of a large cohort of patients with UIA. It will combine accurate clinical phenotyping and comprehensive imaging with CAWE screening.
- Trial name
- U-CAN (NCT04578808)
- Testing
- Unruptured intracranial aneurysms
- Where
- 29 sites in France, Netherlands and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Nantes University Hospital
Brain Aneurysm, Intracranial Hemorrhages
Outcome Study of the Pipeline Embolization Device With Vantage Technology in Unruptured Aneurysms
In this project the investigators study the safety and efficacy of the pipeline embolization device with vantage technology in treatment of unruptured brain aneurysms
- Conditions
- Brain Aneurysm, Intracranial Hemorrhages, Stroke
- Trial name
- PEDVU (NCT05626504)
- Testing
- Pipeline Embolization Device with Vantage Technology
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- King's College Hospital NHS Trust
Unruptured Intracranial Aneurysm, Infarction Cerebral
Chronic Remote Ischemic Conditioning in Small Infarctions Associated with Stent-assisted Coiling of Unruptured Intracranial Aneurysms
1. Disease Description Stent-assisted coiling has become an effective treatment modality for intracranial aneurysms. With continuous advancements in periprocedural antiplatelet regimens, the incidence of symptomatic…
- Trial name
- CRISIS (NCT06826144)
- Testing
- remote ischemic conditioning
- Volunteers
- 84 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cerebral Aneurysm Unruptured, Intracranial Pressure
Remifentanil vs Esmolol During Intubation for Cerebral Aneurysm Coil Embolization
Endotracheal intubation may cause significant increases in blood pressure, heart rate, and intracranial pressure, particularly in patients undergoing cerebral aneurysm coil embolization.
- Trial name
- NCT07660861
- Testing
- Remifentanil, Esmolol
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Intracranial Aneurysm
Low Dose Prasugrel vs Clopidogrel for Stenting or Flow Diverter for Unruptured Aneurysm
Low clopidogrel response has been reported in about 5-44% of the total population, which is associated with an increase in thromboembolism. Recently prasugrel drug widely accepted as a good option for these patients.
- Trial name
- NCT05359224
- Testing
- Prasugrel group, Clopidogrel group
- Where
- South Korea
- Volunteers
- 406 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Intracranial Aneurysm
General Anesthesia vs Local Anesthesia for Endovascular Treatment in Patients With Unruptured Intracranial Aneurysm Using Flow Diverter
The prevalence of unruptured intracranial aneurysm (UIA) in the population is about 2%-7%, and once it ruptures and bleeds, the rate of disability and death is extremely high, with 10%-15% of patients dying suddenly before they…
- Trial name
- GALA-FD (NCT06416657)
- Testing
- Different anesthesia methods, namely local anesthesia and general anesthesia
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Ming Lv
Aneurysm, Aneurysm, Intracranial
Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms With Surpass Elite With GUARDian Flow Diverter (GUARD)
The objective of the Safety and Efficacy of Endovascular Treatment of Intracranial Aneurysms with Surpass Elite with GUARDian Flow Diverter (GUARD) trial is to evaluate the safety and efficacy of the Surpass Elite with Guardian…
- Trial name
- GUARD (NCT06872684)
- Testing
- Surpass Elite with Guardian Flow Diverter System
- Where
- 20 sites in United States
- Volunteers
- 183 people
- Sponsor
- Stryker Neurovascular
Unruptured Intracranial Aneurysms
Brain Lesions Following Endovascular and Surgical Treatment of Unruptured Intracranial Aneurysms
The purpose of this study is to determine the incidence and impact of brain lesions in MRI after coiling and clipping of unruptured intracranial aneurysms on clinical and neurological outcome of patients.
- Trial name
- LESUIA (NCT01490463)
- Where
- Germany
- Sponsor
- Johann Wolfgang Goethe University Hospital
Ruptured Cerebral Aneurysm, Unruptured Cerebral Aneurysm
Microsurgical Clipping and Endovascular Embolization Comparative Prospective Randomized Trial
Despite the active development of surgical methods of treatment (endovascular embolization and microsurgical clipping) of cerebral aneurysms, determining the indications and method of surgical treatment of cerebral aneurysms…
- Trial name
- MONICA (NCT04548856)
- Testing
- Microsurgical clipping, Endovascular embolization
- Volunteers
- 4 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Unruptured Cerebral Aneurysm, Artificial Intelligence (AI)
AI Models for Cerebral Aneurysms Segmentation, Detection and Stability Prediction
Aneurysmal subarachnoid hemorrhage (SAH) is one of the critical diseases that severely threaten human health, with a clinical mortality rate reaching as high as 30%.
- Conditions
- Unruptured Cerebral Aneurysm, Artificial Intelligence (AI), Subarachnoid Hemorrhage, Aneurysmal, Magnetic Resonance Angiography
- Trial name
- AI-CARE (NCT06766422)
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation
Treatment of Brain AVMs (TOBAS) Study
The objectives of this study and registry are to offer the best management possible for patients with brain arteriovenous malformations (AVMs) (ruptured or unruptured) in terms of long-term outcomes, despite the presence of…
- Conditions
- Unruptured Brain Arteriovenous Malformation, Ruptured Brain Arteriovenous Malformation, Arteriovenous Malformations, AVM
- Trial name
- TOBAS (NCT02098252)
- Testing
- Neurosurgery, Radiation therapy, Embolization
- Where
- 30 sites in United States, Brazil and 4 more
- Volunteers
- 1,000 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Unruptured Intracranial Aneurysm
Assessment of the Clinical and Economic Impact of Sim&Size, a Simulation Software for Implantable Devices Used in the Treatment of Intracranial Aneurysms: A Prospective Multicenter Study.
In recent years, endovascular treatment of intracranial aneurysms has seen remarkable growth, now surpassing traditional surgical approaches in terms of frequency of use.
- Trial name
- ESSNAI (NCT07433075)
- Testing
- 3D simulation of placement of neurovascular implantable medical device, Manual planning of endovascular procedure
- Where
- 6 sites in France
- Volunteers
- 576 people
- Sponsor
- Sim&Cure
Intracranial Aneurysm
Screening Intracranial Aneurysms With Magnetic Resonance Angiography (MRA) in China
The Chinese Cerebral Aneurysms Survey is a continuing prospective study among middle-aged and older individuals (35 - 75 years) that aims to determine the prevalence of cerebral intracranial aneurysms in the general population…
- Trial name
- NCT00926172
- Where
- China
- Volunteers
- 4,500 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine