Clinical trials: Cerebral Circulatory Disorder
Muscle Spasticity, Spinal Cord Injury
Comparing Upper Limb Surgery and Botulinum Toxin for Spasticity: A Paired Design Study
Spasticity is a common complication following central nervous system injuries. Left untreated, spasticity can lead to various complications, hindering activities of daily living and diminishing independence.
- Conditions
- Muscle Spasticity, Spinal Cord Injury, Stroke, Traumatic Brain Injuries
- Trial name
- NCT06733025
- Testing
- Tendon lengthening surgery, BoNT Injections
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Vastra Gotaland Region
Ischemic Stroke
Study to Test Sensitivity and Specificity of Passive Wave Pressure Device in Determining Ischemic Stroke
That the Jan Medical Nautilus NeuroWaveTM system provides significantly higher sensitivity to hyper acute ischemic stroke than does CT.
- Trial name
- NCT01643525
- Testing
- Nautilus NeuroWaveTM System
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Jan Medical, Inc.
Stroke
REWIRE - Rehabilitative Wayout In Responsive Home Environments, A Pilot Trial
The study examines the possible application of the rehabilitation platform REWIRE.
- Trial name
- REWIRE (NCT02192125)
- Testing
- REWIRE-System
- Where
- Switzerland
- Volunteers
- 17 people
- Sponsor
- University of Zurich
Congestive Heart Failure, Cardiomyopathy
Cardiac Hormone Replacement With Brain Natriuretic Peptide (BNP) in Heart Failure
The purpose of this study is to determine the effects of subcutaneous injection of Human BNP (nesiritide), a hormone produced by the heart, on the pumping ability of the heart, kidney function, and hormonal function in persons…
- Trial name
- SubqBNP (NCT00252187)
- Testing
- B-type Natriuretic Peptide (BNP)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Horng Chen
Ischemic Stroke, Vertebral Artery Stenosis
Efficacy of Drug-Eluting Vertebral Artery Stenting Treatment for Atherosclerotic Vertebral Arteries Stenosis
This is a prospective, multi-center, open-access, single-arm trial to observe the real-world clinical efficacy of drug-eluting vertebral artery stenting system treatment for Atherosclerotic Vertebral Arteries Stenosis.
- Trial name
- NCT05644314
- Testing
- The drug-eluting stent
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Stroke
"Evaluation Of ALBA® Device for Upper Extremity Motor Function In Adults With Subacute And Chronic Acquired Brain Injury"
As part of the rehabilitation techniques, robotic equipment has been introduced for the rehabilitation of the upper extremity with promising results.
- Trial name
- NCT05824416
- Testing
- Experimental: ALBA, Conventional Therapy
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- uMov
Fabry Disease
A Study of the Safety and Efficacy of Fabrazyme in Patients With Fabry Disease
People with Fabry disease have an alteration in their genetic material (DNA) which causes a deficiency of the alpha-galactosidase A enzyme.
- Trial name
- NCT00196716
- Testing
- Fabrazyme (agalsidase beta)
- Where
- 4 sites in Czechia, Estonia and 2 more
- Volunteers
- 21 people
- Sponsor
- Genzyme, a Sanofi Company
Cryptogenic Stroke, Atrial Fibrillation
Incidence and Predictors of Recurrent Stroke in Cryptogenic Stroke Patients With Atrial Fibrillation
Brief Summary: This study aimed to investigate the risk and factors that predict recurrent stroke in patients who initially had a stroke with no clear cause (called cryptogenic stroke) and were later found to have atrial…
- Conditions
- Cryptogenic Stroke, Atrial Fibrillation, Recurrent Ischemic Stroke
- Trial name
- NCT07126184
- Testing
- Extended Cardiac Monitoring
- Where
- Pakistan
- Volunteers
- 109 people
- Sponsor
- Nangarhar University
Retinopathy of Prematurity, Mydriasis
The Effects of Mydriatic Eye Drops in Retinopathy of Prematurity Examinations
Retinopathy of prematurity (ROP) is a retinal disorder of preterm neonates and a potential cause of blindness. As early diagnosis and treatment preserve vision, very low birth weight infants must be screened for ROP.
- Conditions
- Retinopathy of Prematurity, Mydriasis, Neonatal Disease, Analgesic Adverse Reaction
- Trial name
- NCT05880433
- Testing
- NIRS(INVOS 5100; Covidien Somanetics, Troy, MI
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Training and Research Hospital
Acute Stroke, Ischemic Stroke, Acute
Rescue Carotid Stenting in Tandem Occlusions: 4-year Experience From a Comprehensive Stroke Centre
The rescue carotid stenting has recently been an additional treatment followed by mechanical thrombectomy in tandem occlusions of the anterior circulation.
- Trial name
- NCT06397638
- Testing
- Rescue carotid stenting
- Where
- Vietnam
- Volunteers
- 90 people
- Sponsor
- Can Tho Stroke International Services Hospital
Ischemic Stroke
Ginsenoside-Rd for Acute Ischemic Stroke
The purpose of this study is to evaluate the efficacy and safety of ginsenoside-Rd for acute ischemic stroke.
- Trial name
- NCT00591084
- Testing
- ginsenoside-Rd 10 mg, ginsenoside-Rd 20mg
- Where
- China
- Volunteers
- 199 people
- Sponsor
- Xijing Hospital
Tachycardia, Atrial Fibrillation
Observation of Clinical Routine Care for Patients With BIOTRONIK Implantable Cardiac Monitors (ICMs)
This registry is performed for the long-term assessment of outcome, performance and residual safety aspects of the BIOMONITOR III and possible successors in a real-life clinical set-up.
- Conditions
- Tachycardia, Atrial Fibrillation, Syncope, Bradycardia
- Trial name
- BIOSTREAM-ICM (NCT04075084)
- Where
- 31 sites in Australia, Czechia and 7 more
- Volunteers
- 1,400 people
- Sponsor
- Biotronik SE & Co. KG
Stroke Sequelae
Balance Systems Protocol for Subacute Phase Stroke Patients.
The aim of the study is to evaluate if the application of a protocol focused on the equilibrium systems versus the conventional treatments decreases the time to acquire equilibrium in standing, the risk of falls and favors the…
- Trial name
- BSPStroke (NCT03406026)
- Testing
- Balance System Protocol Stroke, Control Stroke
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Universitat Internacional de Catalunya
Acute Ischemic Stroke, Stroke, Acute
Xingnaojing for Mild-to-severe Acute Ischemic Stroke
The main purpose of this trial is to determine whether Xingnaojing, intravenously administered within 24 hours of symptom onset, improves the daily living ability of acute ischemic stroke at 90 days.
- Conditions
- Acute Ischemic Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- XMAS-2 (NCT04150835)
- Testing
- Xingnaojing injection, Standard care
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Dongzhimen Hospital, Beijing
Non-paroxysmal Atrial Fibrillation
LAA Clipping Versus NOACs to Prevent Stroke in Non-paroxysmal Atrial Fibrillation.
This trial is designed to examine the hypothesis that thoracoscopic LAA clipping is superior to NOACs for stroke, systemic embolism, all-cause mortality, major bleeding events and clinically relevant nonmajor bleeding events in…
- Trial name
- NCT06021808
- Testing
- Thoracoscopic LAA clipping, Novel oral anticoagulant
- Where
- China
- Volunteers
- 290 people
- Sponsor
- China National Center for Cardiovascular Diseases
Stroke
Robot-assisted Hand Rehabilitation for Patients With Stroke
Robotic therapy can deliver larger amounts of upper extremity movement practice for stroke rehabilitation. Although the treatment effects were supported in studies, there are still limitations in clinical intervention.
- Trial name
- NCT03392493
- Testing
- Robot-assisted hand rehabilitation, Standard treatment
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Stroke
Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated with Antithrombotics for an Ischemic Stroke.
Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. There are brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.
- Trial name
- QUATRO (NCT05741593)
- Testing
- Analysis of the verbatim from the transcription of the recorded interviews.
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Carotid Artery Plaque, Aortic Aneurysm
Use of Sublingual Microcirculation and FloTrac Monitoring During Major Vascular Surgery and Its Effect on Hospital LOS
the aim of this study is to determine whether an intraoperative optimization protocol using the enhanced flow-based hemodynamic parameters of the FloTrac/Vigileo device in combination with intraoperative measurement of the…
- Conditions
- Carotid Artery Plaque, Aortic Aneurysm, Aneurysm
- Trial name
- NCT04913493
- Testing
- Cytocam-IDF
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Universitair Ziekenhuis Brussel
Chronic Stroke Patients
Effect of Transcutaneous Auricular Stimulation of the Vagus Nerve on Functional Connectivity in the Brain at Rest
The goal of this clinical trial is to study the effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on resting-state brain functional connectivity.
- Trial name
- COVAGNIRS (NCT07282106)
- Testing
- Active taVNS arm
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Clinique Les Trois Soleils
Subarachnoid Hemorrhage, Severe Traumatic Brain Injury
Outcomes Associated With Application of a Normothermia Protocol in Patients With Severe Neurological Insult and Fever
When fever is present in patients with stroke, traumatic brain injury (TBI), or brain hemorrhage, it has been associated with worse outcomes including larger areas of tissue death, increased length of stay, worse degree of coma…
- Trial name
- SNIF (NCT00890604)
- Testing
- Stepwise normothermia protocol, Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
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