Clinical trials: Cerebral Circulatory Disorder
Unilateral Spatial Neglect, Stroke
Comparing Prism Adaptation Training With and Without TENS to Minimize Unilateral Spatial Neglect
This study aims to find out if doing two treatments together-Prism Adaptation Therapy (PAT) and Transcutaneous Electrical Nerve Stimulation (TENS)-will help people who have had a stroke pay better attention to one side of their…
- Trial name
- NCT07157865
- Testing
- Prism adaptation training combined with TENS, PAT only
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Kettering Health Network
Stroke
This Study Evaluates the Use of a Data-driven Lower Limb Exoskeleton Controller for Stroke Rehabilitation.
The goal of this clinical trial is to test a new, impairment-aware robotic control software framework to see if its smart adaptation can improve walking recovery in healthy adults and chronic stroke survivors. .
- Trial name
- NCT07616167
- Testing
- Unified Control Framework for Lower-Limb Powered Orthosis, Conventional Robotic Controller
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Infant, Premature, Ductus Arteriosus, Patent
Plasma B-Type Natriuretic Peptide Concentrations in Preterm Infants < 28 Weeks
The aim of the study was to evaluate BNP in preterm infants < 28 weeks on the second day of life, when it is still unknown, if a patent ductus arteriosus is hemodynamic significant or not.
- Conditions
- Infant, Premature, Ductus Arteriosus, Patent, Natriuretic Peptide Brain
- Trial name
- NCT00528736
- Where
- Germany
- Volunteers
- 82 people
- Sponsor
- Charite University, Berlin, Germany
Stroke, Inpatients
A Novel Approach to Enhance True Recovery After Stroke
The purpose of this study is to elucidate pathophysiological mechanisms behind gait disturbances during the early recovery phase after hemiparetic stroke to identify targets for new treatment strategies.
- Conditions
- Stroke, Inpatients, Recovery of Function, Observational Study
- Trial name
- NCT05359367
- Testing
- Observational
- Where
- Sweden
- Volunteers
- 6 people
- Sponsor
- Danderyd Hospital
Stroke, Spinal Cord Injuries and Disorders
Spinal Cord Stimulation Combined With Physical Therapy in Post-Stroke Upper-Limb Motor Hemiparesis
This study plans to use systems that have been developed by Medtronic to investigate the use of cervical spinal cord stimulation to treat adults with upper limb hemiparesis resulting from a stroke.
- Conditions
- Stroke, Spinal Cord Injuries and Disorders, Hemiparesis After Stroke
- Trial name
- NCT07153536
- Testing
- Spinal Cord Stimulator (Medtronic Inceptiv™ System), Physical Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Marco Capogrosso
Stroke
Sour Taste and Cold Temperature in Dysphagia
The objective is to establish the effect of sour taste and cold temperature on the pharyngeal swallowing transit time after ischemic hemisphere stroke.
- Trial name
- NCT00780364
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp
Stroke, Acute
Telerehabilitation-Based Early Upper Extremity Training in Stroke Patients
Telerehabilitation method, which is an alternative to face-to-face rehabilitation practices for stroke patients who need intensive, regular and long-term rehabilitation in the early period, has been popularly used in recent…
- Trial name
- NCT06261099
- Testing
- control + working group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Suleyman Demirel University
Ischemic Stroke
Clopidogrel Response in Acute Ischemic Stroke
The aim of this study was to determine the prevalence rate and risk factors for chemical laboratory clopidogrel low-response (CLR) in the acute phase after an ischemic stroke.
- Trial name
- Bo-CRISP (NCT01846572)
- Volunteers
- 159 people
- Sponsor
- Ruhr University of Bochum
Stroke, Gait, Hemiplegic
Effects of an Ankle-Foot Orthosis on Gait While Performing an Attention Demanding Task
We hypothesize that: (1) gait stability will be increased when wearing an ankle-foot orthosis (plastic brace supporting the foot and ankle); (2) an attention demanding task will decrease gait stability and (3) the improvement in…
- Trial name
- NCT01320839
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Nova Scotia Health Authority
Coma, Cardiac Arrest
Combined Whole-brain Structural and Functional MRI for the Prediction of Neurological Recovery After Cardiac Arrest
To assess the performance of a predictive model resulting from the analysis of sMRI/fMRI/contrast-enhanced MRI-derived personalized connectomic data, as compared with standard predictors (clinical examination, electrophysiology…
- Conditions
- Coma, Cardiac Arrest, Disorder of Consciousness, Neurologic Disorder
- Trial name
- ARISE (NCT06617377)
- Testing
- advanced whole-brain sMRI/fMRI/contrast-enhanced MRI scan
- Where
- France
- Volunteers
- 263 people
- Sponsor
- University Hospital, Toulouse
Carotid Artery Stenosis, Strokes
Statin Neuroprotection and Carotid Endarterectomy: Safety, Feasibility and Outcomes
The investigators hypothesize that pre-operative statin use is neuroprotective at maximal doses. The goals are to determine the safety, feasibility, and efficacy of maximizing statin doses for two weeks (12-18 days) prior to CEA…
- Trial name
- STANCE (NCT02850081)
- Testing
- Statin, Atorvastatin
- Where
- 7 sites in United States
- Volunteers
- 31 people
- Sponsor
- Columbia University
Spasticity, Muscle, Stroke
Multimodal Instrumented Assessment of Post-stroke Elbow
The proposed clinical trial will employ the NEUROExos Elbow Module (NEEM), an active robotic exoskeleton, for the passive mobilization and active training of elbow flexion and extension in 60 sub-acute and chronic stroke patients…
- Conditions
- Spasticity, Muscle, Stroke, Upper Limb
- Trial name
- NCT04484571
- Testing
- Neuroexsos elbow module
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Cerebral Hemorrhage, Acute Lobar Haematoma
Descriptive Study on MRI Contrast of Acute Cerebral Hemorrhage in Different Microangiopathies
Cerebral haemorrhage represents a minority of acute vascular syndromes (less frequent than ischemic stroke, at around 20%), but with a therapeutic impasse, having no specific treatment.
- Trial name
- GADO-ICH (NCT06781034)
- Testing
- None, pure observational study
- Where
- France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke, Motor İmagery Ability
Investigation Of The Relationship Between Imagery Ability, Balance And Functionality After Stroke
It was aimed to determine the relationship between post-stroke imagination ability, balance, and functionality, and to compare the motor imagery skills of those who had stroke with compatible healthy individuals.
- Conditions
- Stroke, Motor İmagery Ability, Mental Chronometry, Balance
- Trial name
- NCT04832334
- Testing
- Kinesthetic and Visual Imagery Questionnaire, Box and Block Test, Hand Lateralization Test., Berg Balance Scale, Functional Reach Test, Timed Up and Go Test, Functional Independence Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medipol University
Carotid Atherosclerosis
The Study of Blood Pressure Variability to Impact Arterial Stiffness and Carotid Atherosclerosis
The purpose of this study is to investigate whether and what extent blood pressure variability is associated with arterial stiffness and carotid atherosclerosis, furthermore to compare the difference in the relationship of the…
- Trial name
- NCT01466699
- Volunteers
- 1,235 people
- Sponsor
- Yan Li
Right Ventricular Dysfunction
Right Ventricular Function Changes After CIED Implantation: The RIGHT-CIED Study
This study aims to understand how the right side of the heart changes in people who receive an implantable cardiac electronic device (CIED), such as a pacemaker, ICD, or CRT device.
- Trial name
- RIGHT-CIED (NCT07272395)
- Testing
- Multimodal Right Ventricular Evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
Music Listening for Cardiorespiratory Exercise in Inpatient Stroke Rehabilitation
Stroke survivors struggle to meet clinical recommendations for physical exercise duration and intensity. During the past two decades, music interventions have increasingly shown effectiveness in several motor tasks in stroke…
- Trial name
- NCT05398575
- Testing
- Music
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- University of Aarhus
Depression
Single-Dose Pharmacokinetics (PK) Study of Novel Neurogenic Compound NSI-189
This is a subject single blinded, randomized, placebo-controlled, single dose, first-time-in-human study with three or more ascending cohorts.
- Trial name
- NCT01310881
- Testing
- NSI-189 Phosphate
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Neuralstem Inc.
Acute Ischemic Stroke
Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke
Stroke is a major cause of death and long-term disability in the developed world. While t-PA and mechanical thrombectomy have been shown to decrease disability in properly selected patients, many patients are left with lifelong…
- Trial name
- NCT04918719
- Testing
- Acetylcysteine, Dextrose in Water
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Ataxia Telangiectasia
Body Composition and Hormonal Status in Ataxia Telangiectasia
Ataxia telangiectasia (A-T) is a rare devastating human recessive disorder characterized by progressive cerebellar ataxia, immunodeficiency, chromosomal instability, and cancer susceptibility.
- Trial name
- NCT02345200
- Testing
- bioelectrical impedance analysis, blood draw
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
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