Clinical trials: Cerebral Circulatory Disorder
Fabry Disease
Global Burden and Treatment Trajectiories in Italian Patients With Fabry Disease
GROUND study is an Italian, multicenter retrospective longitudinal cohort study with a cross-sectional phase with the aim to quantify the severe clinical burden in terms of severe and fatal outcomes and extension of clinical…
- Trial name
- GROUND (NCT04916977)
- Testing
- FD patients
- Where
- 7 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Chiesi Italia
Acute Ischemic Stroke
Identification of Stroke Patients ≤ 3 and ≤ 4.5 Hours of Symptom Onset by Fluid Attenuated Inversion Recovery (FLAIR) Imaging and Diffusion Weighted Imaging (DWI)
The aim of the study is to evaluate the use of combined fluid attenuated inversion recovery (FLAIR) imaging and diffusion weighted imaging (DWI) as surrogate marker of lesion age within the first 6 hours of ischemic stroke in…
- Trial name
- PRE-FLAIR (NCT01021319)
- Where
- 2 sites in Germany
- Volunteers
- 643 people
- Sponsor
- Götz Thomalla, MD
Stroke Syndrome
The Effect of Mirror Therapy With Virtual Reality Application on Motor-Sense Acquisition and Quality of Live in Home Care of Stroke Patients
: Aim: Stroke is increasing day by day in our country as in the world. Early rehabilitation after stroke accelerates motor-sensory gains of individuals. This also increases the quality of life.
- Trial name
- NCT05624892
- Testing
- Mirror Therapy with Virtual Reality Application
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Stroke, Acute Traumatic Brain Injury
Clinimetric Application of FOUR Scale as in Treatment and Rehabilitation of Patients With Acute Cerebral Injury
The aim of this study is to increase the effectiveness of clinical monitoring of patients with acute cerebral insufficiency by improving the discriminative ability of the FOUR scale.
- Conditions
- Stroke, Acute Traumatic Brain Injury, Subarachnoid Hemorrhage
- Trial name
- FOURACI (NCT06043167)
- Testing
- The predictive value russian rendition the FOUR score.
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Surgut Clinical Trauma Hospital
Stroke
Telehealth Intervention Involving HEARTS Technical Package and Activity Monitor to Promote Physical Activity Post-stroke
Objectives: The aim of this feasibility randomized controlled trial (RCT) study is to investigate whether the theoretically informed telehealth intervention involving the HEARTS Technical Package and the use of an activity…
- Trial name
- NCT06068036
- Testing
- Telehealth intervention: HEARTS technical package + activity monitor (Smartwatch Mi Band 7®), Telehealth intervention: HEARTS technical package
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Federal University of Minas Gerais
Stroke, Physical Disability
Robotic Versus Conventional Therapy For Post-Stroke Hand Motoric Recovery
This clinical trial aims to compare the effectiveness of Robotic versus conventional mirror therapy among post-stroke patients. The main questions it aims to answer are: Effectiveness of both interventions in hand motoric…
- Conditions
- Stroke, Physical Disability, Upper Extremity Paresis
- Trial name
- NCT06155058
- Testing
- SYREBO, Conventional Mirror Method
- Where
- 3 sites in Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Stroke, Atrial Fibrillation
Differences in ECG- vs. proLonged cardIac MonItor-DeTected Atrial Fibrillation in STROKE Patients (DELIMIT AF-STROKE)
The present study is an investigator-initiated, single-center, retrospective study based on data from the London Ontario Stroke Registry (LOSR), aiming to compare the characteristics and outcomes of ECG-detected and…
- Conditions
- Stroke, Atrial Fibrillation, TIA
- Trial name
- NCT05822791
- Testing
- Prolonged cardiac monitoring, ECG
- Where
- Canada
- Volunteers
- 366 people
- Sponsor
- Luciano A. Sposato
Ischemic Stroke, Covid 19
Endovascular Thrombectomy in COVID-19 Infected Patients
About 5% of COVID-19 patients may present symptoms related to acute ischemic stroke (AIS). Treatment-management and outcomes related to mechanical thrombectomy (MT) for COVID-19 infected patients harboring large vessel occlusion…
- Trial name
- ET-COVID-19 (NCT04406090)
- Testing
- Mechanical Trombectomy
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Montpellier
Stroke
Efficacy and Acceptability of the Luna EMG Rehabilitation Robot on Motor Recovery of the Upper Limb in the Chronic Phase of Stroke
Recent work on large cohorts of chronic stroke (>6 months post-stroke) have shown that intensive training of the upper limb in the chronic stroke patients can lead to substantial motor and functional gains that are maintained at…
- Trial name
- LUNASTROKE (NCT05902910)
- Testing
- LUNA-EMG Robot
- Where
- France
- Volunteers
- 5 people
- Sponsor
- University Hospital, Brest
Carotid Artery Disease, Stroke
Carotid Artery Stenting Outcomes in the Standard Risk Population for Carotid Endarterectomy
The objective of the CANOPY trial is to assess the continued safety and effectiveness of the RX Acculink Carotid Stent System under commercial use in subjects at standard risk for adverse events from Carotid Endarterectomy (CEA)…
- Conditions
- Carotid Artery Disease, Stroke, Amaurosis Fugax, Transient Ischemic Attack (TIA)
- Trial name
- CANOPY (NCT01445613)
- Testing
- RX Acculink Carotid Stent System (RX Acculink)
- Where
- United States
- Volunteers
- 1,203 people
- Sponsor
- Abbott Medical Devices
Stroke
Muscle Tone Changes in Acute Stroke According to Brain Injury
The purpose of the study is to examine connections between muscle tones, strength and function after stroke.
- Trial name
- NCT01041560
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Jyväskylä Central Hospital
Stroke
Determining the Optimal Dose of Reactive Balance Training After Stroke
Falls in daily life are one of the most significant complications for people with stroke. Fall rates are particularly high soon after discharge from stroke rehabilitation.
- Trial name
- NCT04219696
- Testing
- Reactive balance training
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Toronto Rehabilitation Institute
Chronic SDH and the Efficacy of Embolization
Endovascular Embolization for Chronic Subdural Hematomas Following Surgical Evacuation
This study is designed to evaluate the effectiveness of endovascular embolization of middle meningeal artery following evacuation of subdural hematomas (SDHs) to assess rate of recurrence.
- Trial name
- endovascular (NCT04272996)
- Testing
- Craniotomy only, Craniotomy + Endovascular embolization of the middle meningeal vessels
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Augusta University
Horton Disease
Velocimetric Study of Temporal Arteries in Patients With Horton Disease Using Scan-Doppler
The use of ultrasonography in detecting giant cell arteritis ( GCA) is emerging. Currently, temporal biopsy is the gold standard to diagnose GCA but studies have shown the interest to use B mode ultrasonography.
- Trial name
- VELHOR (NCT03360162)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Brest
Stroke, Cognitive Symptoms
Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS)
Between 1 and 5 percent of patients who have coronary artery bypass surgery suffer a stroke following surgery, and 30 percent have new brain lesions that do not produce symptoms and are seen only on MRI.
- Trial name
- NCT00391378
- Where
- United States
- Volunteers
- 363 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Effects of Robotic Rehabilitation in Post-Stroke Patients
This study aims to evaluate the effect of robotic rehabilitation through training on a robot-assisted orthostatic board and neuromuscular electrical stimulation (NMES) on functionality in post-stroke patients.
- Trial name
- NCT04494685
- Testing
- Intervention group (Robotic rehabilitation), Control group (Conventional physiotherapy)
- Volunteers
- 40 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Stroke
Merging Yoga and Group OT (MY-OT) to Improve Balance and Decrease Fall Risk After Stroke
The long-term goal of this project is to advance best practices in occupational therapy (OT) to manage fall risk factors and reduce fall rates in older adults with stroke.
- Trial name
- MY-OT (NCT02933515)
- Testing
- yoga and occupational therapy
- Volunteers
- 14 people
- Sponsor
- Colorado State University
Stroke, Acute, Ischemic Stroke
Melatonin in Acute Stroke
This study will measure Interleukin 6 (IL-6), a well-documented inflammatory biomarker that is increased in the acute phase of stroke, and to compare its levels after the administration of melatonin - a well-documented…
- Trial name
- NCT03843008
- Testing
- Melatonin
- Where
- United States
- Sponsor
- University of Florida
Stroke
GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy
We aim to determine if targeted high-definition transcranial direct current stimulation (HD-tDCS) can safely correct errors in visual verticality perception in patients after stroke affecting either hemisphere.
- Trial name
- GravNegElect (NCT06747676)
- Testing
- Active: High-Definition transcranial Direct Current Stimulation (HD-tDCS)
- Where
- 2 sites in Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo
Stroke
Evaluation of Improvement in Mobility Skills for Sub-acute Stroke Patients, Using the Selfit System.
Stroke is a leading cause of mobility disability for adults. Selfit is an advanced practice system that enables a wide range of exercises to improve patient mobility in the sub-acute stage after a stroke.
- Trial name
- Selfit (NCT03671876)
- Testing
- Intervention plus therapy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Selfit Medical
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