Clinical trials: Cerebral Circulatory Disorder
Stroke
TENS and Spasticity in Stroke Patients
study aims to evaluate the efficacy of high and low frequency TENS on spasticity, strength and functional status in stroke patients.
- Trial name
- NCT05075109
- Testing
- High Frequency TENS, Low Frequency TENS, Task Related Training
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Phenylketonurias, Nutritional and Metabolic Diseases
Comparison of Atherogenic Risk Factors and Efficacy of Nutritional Treatment Among Adult Phenylketonuria Patients
Phenylketonuria is a rare metabolic disease that results from the absence or near-absence activity of the enzyme phenylalanine hydroxylase, which metabolizes the amino acid phenylalanine to tyrosine in the body.
- Trial name
- NCT04969809
- Testing
- Ultrasound of the jugular veins, addition of phenylalanine-free protein substitutes
- Volunteers
- 50 people
- Sponsor
- University Medical Centre Ljubljana
Dementia, Motor Impairments
PERDOVE ANZIANI: a Prospective Cohort Study on Older Patients
This prospective observational cohort study aims at studying functional and clinical outcomes of patients (N = 329) admitted to 4 geriatric hospital facilities of the St John of God Order in Northern Italy during an index period…
- Conditions
- Dementia, Motor Impairments, Stroke, Thighbone Fractures
- Trial name
- NCT01699984
- Where
- 4 sites in Italy
- Volunteers
- 329 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Intracranial Aneurysm
@neurIST : Intregrated Biomedical Informatics for the Management of Cerebral Aneurysms
The primary aim of the SwissNeuroFoundation AneurysmDataBase Project is to implement information technology based tools to create and use a holistic reference database specific to intracranial aneurysms (IA).
- Trial name
- @neurIST (NCT05526352)
- Where
- 22 sites in United States, Canada and 9 more
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Stroke, Ischemic, Thrombectomy
Prognostic Value of Isolated and Combined Score Aspects in Acute Ischemic Stroke
This study, called TARGET-ASPECT, looks at patients who had a type of stroke called acute ischemic stroke and were treated with clot-busting medicine and a procedure to remove the clot.
- Conditions
- Stroke, Ischemic, Thrombectomy, Thrombolytic Therapy, Brain Ischemia
- Trial name
- NCT07069452
- Where
- France
- Volunteers
- 152 people
- Sponsor
- Centre Hospitalier de Gonesse
Moyamoya Disease
Clinical Evaluation of the Safety and Efficacy of "Buyan Huan Wu Tang" Combined With Atorvastatin in the Treatment of Atypical Pneumonia
Moyamoya disease, also known as "smoky vein disease," is a relatively rare chronic form of cerebral artery occlusion. The exact cause of this condition is currently unknown.
- Trial name
- NCT07906652
- Testing
- Atorvastatin, Replenishing Five Herbs Decoction
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Heart Failure, Arrhythmias
Comparison Study of BNP and Thoracic Impedance Measurements on Arrhythmias
It is hypothesized that elevated BNP level correlate with an elevated thoracic impedance/fluid index as measured separately by CRT-D devices and external impedance cardiography.
- Trial name
- NCT00580255
- Where
- United States
- Sponsor
- University of California, Davis
Stroke Patients With Hemiplegia or Hemiparesis in the Subacute Stage
The Effect of Combined Transcranial Pulse Current Stimulation (tPCS) and Transcutaneous Electrical Nerve Stimulation (TENS) on Lower Limb Motor Function in Subacute to Chronic Stroke Patients With Hemiplegia (COMPENSATOR-Stroke)
The goal of this study is to evaluate the effects of high frequency tPCS + TENS compared to Sham device stimulation + TENS (Control) in lower limb motor function recovery in stroke patients with hemiplegia or hemiparesis in the…
- Trial name
- COMPENSATOR (NCT06999876)
- Testing
- The AscenZ-VIII Stimulator (Investigational Medical Device)
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- National University Health System, Singapore
Stroke, Acute, TBI
Tracheostomy With Bedside Simultaneous Gastrostomy Vs Usual Care Tracheostomy And Delayed Gastrostomy Placement
There is currently no prospective study analyzing the effect of tracheostomy with bedside simultaneous gastrostomy versus tracheostomy with delayed gastrostomy placement (TSG versus TDG) on the outcomes of neurocritically-ill…
- Conditions
- Stroke, Acute, TBI, Neuromuscular Diseases, Status Epilepticus
- Trial name
- BEGASTON (NCT04758052)
- Testing
- Timing of placement
- Where
- United States
- Sponsor
- University of Mississippi Medical Center
Stroke
Potential for Recovery of Voluntary Finger Extension After Stroke
Stroke patients with absent voluntary finger extension (VFE) 6-months after stroke are not expected to recover hand function. However, experience from the Queen Square Upper Limb neurorehabilitation service contradicts this view.
- Trial name
- PROVES (NCT07592247)
- Testing
- Neuromuscular Electrical Stimulation and Home Exercise Programme
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University College, London
Hypoxic Encephalopathy
The Neurological Pupil Index (NPi) on Intensive Care Unit (ICU) Trial
The trial will evaluate the use of the "Neurological Pupil index" NPi, measured with the digital pupillometer (NeurOptics) compared to clinical examination for better reliability.
- Trial name
- NPI-ON-ICU (NCT01920347)
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Arteriovenous Fistula, Arteriovenous Graft
Access Creation for Hemodialysis: Association With Structural Changes of the Heart
The purpose of this study is to determine if the creation of a fistula or a graft plays a role in the development of heart disease for patients undergoing hemodialysis
- Conditions
- Arteriovenous Fistula, Arteriovenous Graft, Left Ventricular Hypertrophy, Brain Natriuretic Peptide
- Trial name
- NCT00368147
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- Ottawa Hospital Research Institute
Healthy, Multiple Sclerosis
Normal Chinese Lifespan Brain Charts Initiative (NCLBCI)
Major brain diseases (including neuroimmune diseases, neurodegenerative diseases, and cerebrovascular diseases) are leading causes of death and disability in humans.
- Conditions
- Healthy, Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Neurodegenerative Diseases
- Trial name
- NCT06643858
- Testing
- No intervention
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke, Intracranial Hemorrhages
Novel Oral Anticoagulants in Stroke Patients
The present study will monitor and explore acute neurovascular emergencies in patients treated with NOACs compared to those under treatment with VKAs.
- Trial name
- NOACISP (NCT02353585)
- Where
- Switzerland
- Volunteers
- 1,050 people
- Sponsor
- University Hospital, Basel, Switzerland
Stroke
Rehabilitation of the Stroke Hand at Home
The purpose of this research is to evaluate a therapy delivery system for stroke patients that provide accessible, affordable stroke care.
- Trial name
- HAAPI (NCT01144715)
- Testing
- Hand Mentor (TM) robotic stroke therapy device, Home Therapy Program
- Where
- 2 sites in United States
- Volunteers
- 99 people
- Sponsor
- Kinetic Muscles
Stroke
The Effect of Hand Massage on Pain, Anxiety, and Comfort Levels of Intensive Care Patients
This study titled "Evaluation of the Effect of Hand Massage on Patients' Pain, Anxiety and Comfort Levels" aims to determine the effect of hand massage on patients in intensive care units.
- Trial name
- NCT06808906
- Testing
- Hand Massage Application
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Sakarya University
Stroke, Ischemic, Intracranial Atherosclerosis
Predictors of Intracranial Atherosclerotic Disease in Posterior Circulation: a Cohort Study
Early identification of intracranial atherosclerotic disease (ICAD) may impact the management of patients undergoing mechanical thrombectomy (MT).
- Conditions
- Stroke, Ischemic, Intracranial Atherosclerosis, Posterior Circulation Brain Infarction
- Trial name
- NCT06453252
- Testing
- we are aiming to develop a Scoring system based on certain variables derived from both groups
- Where
- 2 sites in United States, Egypt
- Volunteers
- 150 people
- Sponsor
- Sohag University
Stroke, Neglect
Comparison of Concentric or Eccentric Virtual Reality Training Program in Subacute-stroke Patients With Hemispatial Neglect
The purpose of this study is to compare and analyze how the visual gaze training in the afferent direction and the visual gaze training in the efferent direction using virtual reality affects the improvement of the neglect…
- Trial name
- NCT04651335
- Testing
- afferent virtual reality program, efferent virtual reality program
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Yonsei University
Septic Shock, Multiple Organ Failure
Severe Sepsis/Septic Shock on Admission to the General Surgical ICU
Severe sepsis/septic shock are serious complications of infection with high morbidity and mortality. Recent information showed that early and aggressive resuscitation may help improving survival and outcome especially the…
- Conditions
- Septic Shock, Multiple Organ Failure, Fatal Outcome
- Trial name
- NCT01363635
- Where
- Thailand
- Volunteers
- 800 people
- Sponsor
- Mahidol University
Subarachnoid Hemorrhage
HyperHAES Versus Placebo - Effect on Intracranial Pressure in SAH Patients
The purpose of this study is to determine whether 7.2% NaCl in 6% hydroxyethyl starch will lower intracranial pressure (ICP) in SAH-patients with normal or moderately elevated ICP in a placebo controlled study, and to describe…
- Trial name
- NCT00199706
- Testing
- 7.2% NaCl in 6% hydroxyethyl starch solution
- Volunteers
- 20 people
- Sponsor
- Oslo University Hospital
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