Clinical trials: Cerebral Concussion
Fixation, Ocular, Brain Concussion
Concussion Pen Screening Tool
To compare the use of the Concussion Pen to current clinical care practice. This will be a prospective study of a maximum of 24 subjects, with a goal enrollment of 20 subjects (10 in each cohort).
- Trial name
- NCT05432752
- Testing
- Concussion Pen
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Children's Mercy Hospital Kansas City
Post-Concussion Syndrome
Rehabilitation in Post Concussion Syndrome
This project evaluates and quantifies the effects of an individually tailored exercise program applied to patients with long-lasting symptoms after concussion, minor traumatic brain injury, so-called Post-Concussion Syndrome…
- Trial name
- REPCon (NCT05785000)
- Testing
- Physical exercise programme as an add-on, Control patients receiving usual care
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Concussion, Mild, Traumatic Brain Injury, Mild
Mag Con: Efficacy of Oral Mag. in Acute Concussion in Adolescents
This randomized trial will compare the clinical efficacy of adding oral magnesium oxide to acetaminophen and ondansetron in the treatment of adolescents presenting within 48 hours of a mild traumatic brain injury using the…
- Trial name
- NCT05065528
- Testing
- Magnesium
- Where
- United States
- Sponsor
- Corewell Health South
Mild Traumatic Brain Injury
Olfactory Function in Patients With Acute Mild Traumatic Brain Injury
In this project the investigators aim to evaluate olfactory and non-olfactory function in patients within the first 24h following a mild traumatic brain injury (acute mTBI) and compare their results to a group of age and sex…
- Trial name
- NCT02977728
- Testing
- Olfactory Evaluation
- Volunteers
- 42 people
- Sponsor
- Hôpital de Viege
Mild Traumatic Brain Injury (mTBI), Sports-related Concussion
Mobile Dual-Task Brain and Balance Intervention for Concussion Recovery
This research study examines recovery after a sports-related concussion or mild head injury. Many athletes experience lingering problems with thinking, balance, and mood months after a concussion.
- Conditions
- Mild Traumatic Brain Injury (mTBI), Sports-related Concussion, Heart Rate Variability (HRV), Walking
- Trial name
- NCT07599475
- Testing
- Home-Based Mobile Dual-Task Intervention (BraW-Day™)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Hyunhwa Lee
Brain Injuries, Traumatic
Head and Intraocular Trauma Tool for the Identification of Mild Traumatic Brain Injury
Rebion has developed a device, the Rebion trauma tool (referred to as the head and intraocular trauma tool, or "HITT"), that detects ocular fixation and alignment using a binocular retinal scan.
- Trial name
- NCT05092295
- Testing
- Head and Intraocular Trauma Tool, SCAT-5
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rebiscan, Inc.
Brain Concussion, Posttraumatic Stress Disorder
Brain Injury Outcomes (BIO) Study
Many active duty military, national guard, and reserves personnel who served in the recent conflicts in Afghanistan and Iraq were exposed to blasts and other mechanisms of traumatic brain injury (TBI).1,2 Although physical trauma…
- Conditions
- Brain Concussion, Posttraumatic Stress Disorder, Dementia
- Trial name
- BIO (NCT00724607)
- Where
- United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Mild Traumatic Brain Injury, Suicide Prevention
Crisis Response Planning in Military Personnel With Mild Traumatic Brain Injury
The study purpose is to test the effect of Crisis Response Planning (CRP) when used as the second method of suicide prevention in military service members who are at risk for suicide due to mild traumatic brain injury (mTBI).
- Conditions
- Mild Traumatic Brain Injury, Suicide Prevention, Suicide Risk | Patient, Suicide Risk
- Trial name
- NCT07327567
- Testing
- Crisis Response Planning
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Concussion (Diagnosis)
Nature as Medicine for the Healing Brain: Utilization of a Nature-based Exposure Intervention for Decreasing Concussion Recovery Timeline and Symptom Load
The overall goal of this research is to provide pilot data that informs and drives a larger scale research project, incorporating multiple contemporary measurement modalities, to understand the utility and pathological mechanisms…
- Trial name
- NCT07642739
- Testing
- Nature-based Guided Awareness Group, Standard Guided Awareness Group
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Penn State University
Concussion
Telehealth Specialty Concussion Treatment for Youth
Specialty concussion care can help youth recover more quickly but many youth face barriers to accessing concussion specialists. A care delivery model whereby concussion specialists are available to co-manage injuries with primary…
- Trial name
- SPEEDYRecovery (NCT07736534)
- Testing
- Specialist and Pediatrician Co-Management for Early and Effective Concussion Care Delivery to Hasten Your Recovery (SPEEDY Recovery)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rhode Island
Brain Concussion, Mild Traumatic Brain Injury
Concussion Recovery and Support Program
Pilot randomized controlled trial (RCT) comparing a novel intervention Concussion Recovery and Support Program (CRISP) for adolescents and young adults (AYA) 18-29 yo with concussion/ mild TBI.
- Conditions
- Brain Concussion, Mild Traumatic Brain Injury, Headache
- Trial name
- CRISP (NCT07097792)
- Testing
- CRISP (Concussion Recovery and Support Program)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Seattle Children's Hospital
Traumatic Brain Injury
Defining Axonal Injury in Children With Mild Traumatic Brain Injury
To measure Axonal Injury in children with mild traumatic brain injury enrolled in an Emergency Department using Diffusion Tensor Imaging, a type of MRI and biomarkers.
- Trial name
- NCT01922531
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Post Concussion Syndrome
Assessing the Effects of a Clinical Exercise Protocol on Children With Post-concussion Syndrome
The general consensus in sports medicine demonstrates a graduated return to activity protocol for individuals with post-concussion syndrome.
- Trial name
- NCT02459145
- Testing
- Graduated exercise protocol
- Where
- United States
- Sponsor
- University of Arizona
Concussion, Brain, Near Point Convergence
Efficacy of Brock String Therapy Post Concussion
The purpose of the proposed study is to evaluate the efficacy of Brock String therapy prescribed in the acute stage of concussion recovery can improve clinical outcomes among patients with receded near point of convergence (NPC).
- Trial name
- NCT04076657
- Testing
- Brock String Therapy, Standard of Care
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Mild Traumatic Brain Injury
Photobiomodulation for Concussions: the Use of the ImPACT® Test as an Assessment Tool
Brain photobiomodulation (PBM) therapy is an innovative modality for the stimulation of neural activity in order to improve brain function and is currently under investigation as a treatment for several diverse neurological…
- Trial name
- NCT04823507
- Testing
- BIOFLEX DUO+
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- Meditech Rehabilitation Centre
Post-Concussion Syndrome
Craniosacral Therapy for Concussion Symptoms
This study investigated the utilization of CranioSacral Therapy (CST) in patients with Post-Concussion Syndrome (PCS) and capture patient-reported perceptions of their lived experiences of treatment effect upon their symptoms.
- Trial name
- NCT04820192
- Testing
- Craniosacral Therapy
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Special Therapies, Inc.
Healthy
Naturally Produced Cannabinoids for Neuroprotection From Concussion
The goal of this double-blind, placebo-controlled, cross over study is to learn about the neuroprotective properties of a broad-spectrum cannabinoid formulation in normal healthy adults engaged in elite contact sport competition.
- Trial name
- NCT07715864
- Testing
- Broad spectrum cannabinoid formulation
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Regina
Mild Traumatic Brain Injury, Concussion, Mild
Exercise as Concussion Therapy Trial- 2
This study is a Phase 2, open-label study of a therapeutic intervention (graded exercise)compared to a reference therapy (passive stretching) in patients who have sustained mTBI.
- Trial name
- ExACTT (NCT04578743)
- Testing
- Graded Exercise Therapy: ClearPlay(TM)
- Where
- 3 sites in Australia
- Volunteers
- healthy volunteers welcome
- Sponsor
- ANSwers Neuroscience, Inc.
Concussion, Mild, Sport Injury
A Comparison Between Cardiovascular Exercise Modes Following Sport Related Concussion
Primary Aim: Compare physiological (e.g., heart rate) and clinical responses (e.g., symptom provocation) of adolescent and adult athletes (14-35 years of age) completing either a structured treadmill running or a dynamic aerobic…
- Trial name
- NCT04586179
- Testing
- Aerobic (treadmill) Exercise, Dynamic (Agility) Exercise
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Pittsburgh
Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic
Effect of Mental Imagery in Patients With Persistent Post-concussion Symptoms
Background: Mild Traumatic Brain Injury (mTBI) often results in persistent emotional, cognitive, and somatic symptoms-such as headaches and dizziness.
- Conditions
- Mild Traumatic Brain Injury, Concussion, Post Concussive Syndrome, Chronic, Post Traumatic Headache
- Trial name
- NCT07166536
- Testing
- Provocation Test for Symptoms Using Mental Imagery
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Reuth Rehabilitation Hospital