Clinical trials: Cerebral Concussion
Post-Traumatic Stress Disorders, Traumatic Brain Injury
Rural Veterans With Post-traumatic Stress Disorder (PTSD) And Comorbid Mild Traumatic Brain Injury (TBI): A Feasibility Study
This study is being conducted to understand whether training in tasks that require perceiving and thinking about things, or cognition, can improve memory in veterans who have been exposed to a blast explosion and have TBI and…
- Trial name
- NCT01278316
- Testing
- Control, Cognitive Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Michael E. DeBakey VA Medical Center
Brain Concussion
Tissue Repository and Master Database for Concussion Biomarker and Risk Calculator Development
The purpose of this study is to prospectively collect a comprehensive, multi-modality set of diagnostics on patients who have had a concussion, repeating some of these tests serially over time, so that the investigators may then…
- Trial name
- NCT02519998
- Testing
- Concussion
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Traumatic Brain Injury, Brain Concussion
Vestibular Rehabilitation and Balance Training After Traumatic Brain Injury
The main aim of this study is to evaluate the effect of vestibular rehabilitation and balance training on patients with dizziness and balance problems after traumatic brain injury.
- Conditions
- Traumatic Brain Injury, Brain Concussion, Head Injury, Dizziness
- Trial name
- VRTBI2012 (NCT01695577)
- Testing
- Multidisciplinary evaluation and VR, Multidisciplinary evaluation
- Where
- Norway
- Volunteers
- 65 people
- Sponsor
- Oslo University Hospital
Sport-related Concussion
Sub-acute Exercise Following Sport-Related Concussion
Determine the safety and efficacy of sub-maximal aerobic exercise during the subacute phase of recovery following sport-related concussion.
- Trial name
- NCT03575455
- Testing
- Exercise
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Mild Brain Traumatic Injury, Compliance, Patient
Interest of the S100B Protein Assay in Mild Traumatic Brain Injuries at the DOUAI Hospital
The main objective is to evaluate the feasibility and interest of setting up a protocol for the systematic measurement of the S100B protein in patients with mild traumatic brain injury admitted to the emergency room of Douai…
- Trial name
- PS100BTCL (NCT05285774)
- Where
- France
- Volunteers
- 258 people
- Sponsor
- Centre Hospitalier de Douai
Traumatic Brain Injury
TBI MR Study 3 Houston Methodist
This hypothesis-generating feasibility study to determine potential associations between a broad range of clinical neurological symptoms and Magnetic Resonance Image (MRI), data, and clinical findings involved in mild traumatic…
- Trial name
- NCT02218216
- Testing
- MRI Diagnostic
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- GE Healthcare
Normative, Concussed
Investigator Initiated Protocol for the: Evaluation of the Effectiveness and Clinical Utility of Brain Network Activation (BNA™) Technology in the Management of Sport Related Concussion and the Establishment of Normative Data in Youth and Adolescents Athletes
This study's objectives are: To prospectively examine changes in brain network activation (BNA™) from baseline to recovery (i.e., return to activity) in youth and adolescent athletes with concussion.
- Trial name
- NCT02105935
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- ElMindA Ltd
Post Traumatic Stress Disorder
Quetiapine Augmentation of PE Therapy for the Treatment of Co-occurring PTSD and Mild Traumatic Brain Injury
A pilot study to evaluate feasibility for a full-scale merit application. Specifically, for veterans considering prolonged exposure (PE) therapy, following the model established by Foa et al, we need to establish safety, and…
- Trial name
- NCT04280965
- Testing
- Quetiapine Fumarate, Standard of care meducations
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Brain Concussion
LED Therapy for the Treatment of Concussive Brain Injury
A double blind randomized trial of light-emitting diode (LED) therapy for patients suffering from mild traumatic brain injury (mTBI).
- Trial name
- NCT02383472
- Testing
- MedX Health Console model 1100
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Brain Concussion, Post-Concussion Symptoms
Perceptual-Cognitive Training After a Mild Traumatic Brain Injury: Towards a Sensitive Marker for Recovery
This study is part of a larger, multi-centered project done with the collaboration of University Of Victoria. This study holds three separate studies on the mild traumatic brain injured population and the use of…
- Conditions
- Brain Concussion, Post-Concussion Symptoms, Concussion
- Trial name
- NCT03213730
- Testing
- 3D-MOT Neurotracker, Visual Attention Intervention
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Brain Concussion, Cerebral Concussion
Concussion in French Non-professional Handball League : Efficiency of a Concussion Protocol, the White Card Process
Sport related concussion is a major issue for many contact sports, such as Rugby, Football, Hockey and Handball. As a response, some federations like World Rugby set up a concussion protocol, that starts with the referee having…
- Trial name
- PRECCOCE (NCT06365944)
- Where
- France
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Bordeaux
Concussion, Mild, Mild Traumatic Brain Injury
Post-Concussion Aerobic Exercise
This study is looking at the specific role of an exercise prescription on recovery from concussion symptoms in the general population.
- Trial name
- NCT04539509
- Testing
- Exercise Prescription, Treadmill Test, Monitoring
- Where
- Canada
- Sponsor
- University Health Network, Toronto
Brain Injuries, Traumatic
Testing Mild Traumatic Brain Injury (mTBI) in Diverse Athletic Groups
Study will test the use of a short virtual reality driven goggle test as a means of detecting mTBI in a diverse group of athletes
- Trial name
- NCT03515967
- Testing
- I-PAS Goggles
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Miami
Concussion, Mild
Predicting Concussion Outcomes With Salivary miRNA
The purpose of this study is to identify changes in salivary ribosomal nucleic acid (RNA) expression that are predictive of symptom duration and character following mild traumatic brain injury (mTBI) in children.
- Trial name
- NCT02901821
- Testing
- salivary RNA collection
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Concussion, Mild
Return to Learn Implementation Bundle for Schools (RISE) After Youth Concussion
Using the Consolidated Framework for Implementation Research, as our overarching conceptual framework, this translational 2 ½ year pragmatic RCT uses a clustered, stepped wedge design to test the effectiveness of a school-based…
- Trial name
- NCT04635475
- Testing
- RISE Bundle
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Washington
Traumatic Brain Injury, Concussion, Mild
fMRI-neuronavigated rTMS Treatment for Symptoms of Depression Associated With Concussive TBI in the Military Population
This study aims to investigate the efficacy and tolerability of fMRI-targeted repetitive transcranial magnetic stimulation (rTMS) in the treatment of depressive symptoms in service members with a history of concussive traumatic…
- Conditions
- Traumatic Brain Injury, Concussion, Mild, Depressive Symptoms
- Trial name
- NCT03523507
- Testing
- Active: rTMS
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Brain Concussion
Sleep After Adolescent Concussion
The purpose of this research study is to learn more about how sleep changes as teens recover from concussions. We also want to learn if we can improve sleep in teens who have concussions.
- Trial name
- NCT03781076
- Testing
- Sleep Intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Chronic Traumatic Encephalopathy
Post-Concussion Syndrome in Professional Athletes: A Multidisciplinary Study
to examine the relationship between repeated concussions and late decline of brain function. In addition, all participants agreeing to participate in the study will be asked to will their brains to The Krembil Neuroscience Centre…
- Trial name
- NCT03218332
- Testing
- Biomarkers for detecting possible CTE invivo
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Concussion, Mild
Delivery of Digital Cognitive Behavioural Therapy Following Concussion
Concussion is common and patients can go on to suffer with a constellation of symptoms which impacts their functional outcome and quality of life.
- Trial name
- HEADON (NCT05069948)
- Testing
- HeadOn
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University of Edinburgh
Healthy Athlete
Movement Assessment for Concussion Management
Previous work in the area of concussion management has focused heavily on neuro-cognitive testing. In addition to routine neuro-cognitive testing through Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT),this…
- Trial name
- NCT02776904
- Testing
- Immediate Post-concussion Assessment and Cognitive Testing, Gait with single and dual task, Y-Balance test
- Where
- United States
- Volunteers
- 327 people, healthy volunteers welcome
- Sponsor
- University of Arkansas