Clinical trials: Cerebral Hemiplegia
Perinatal Stroke
Intensive Motor Training After Perinatal Stroke to Enhance Walking
Early childhood injuries such as perinatal (around birth) stroke are devastating because the child lives with the problem for life, typically close to a normal lifespan.
- Trial name
- NCT01773369
- Testing
- Early leg training, Delayed leg training, Parent leg training
- Where
- 2 sites in Canada
- Volunteers
- 33 people
- Sponsor
- University of Alberta
Stroke, Cerebrovascular, Hemiplegia and Hemiparesis
BCI Driving FES and Hand Orthosis for Upper Limb Rehabilitation in Chronic Stroke
Multi-center, randomized, sham-controlled, double-blind, longitudinal, experimental clinical study to investigate functional recovery effects on the upper limb in chronic stroke patients and the accompanying neural plasticity…
- Conditions
- Stroke, Cerebrovascular, Hemiplegia and Hemiparesis, Stroke/Brain Attack
- Trial name
- NCT06179745
- Testing
- EEG-based brain-computer interface, Functional Electrical Stimulation, Active hand orthosis
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- University of Essex
Stroke, Hemiplegia
Virtual Reality-Based Mirror Therapy and FES-Cycling in Stroke Rehabilitation
This randomized controlled, assessor-blinded study aimed to compare the effects of virtual reality-based mirror therapy (VRBMT) and functional electrical stimulation-assisted cycling (FES-cycling) when combined with conventional…
- Conditions
- Stroke, Hemiplegia, Upper Extremity Impairments
- Trial name
- NCT07666308
- Testing
- Conventional Rehabilitation, Virtual Reality-Based Mirror Therapy, Functional Electrical Stimulation-Assisted Cycling
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara City Hospital Bilkent
Stroke Sequelae
Efficacy and Safety of Deep Brain Stimulation in Mesencephalic Locomotor Region（MLR） for Poststroke Hemiplegia
Abstract: Background: The leftover movement disorder of stroke patients is one of the main causes of disability, and there is still no specific solution.
- Trial name
- NCT05968248
- Testing
- MLR-DBS, Conventional rehabilitation group
- Volunteers
- 62 people
- Sponsor
- Chinese PLA General Hospital
Hemiplegia, Spasticity
Upper Limb Nerve Cryoneurolysis is Non Inferior to the Usual Care and Has Therapeutic Add Value in Dealing With Shoulder Pain and Functional Problems Caused by Spasticity and Motor Impairment
This trial is part of the spastiCRYO clinical research project. The primary objective of this clinical trial is to test the hypothesis: "Upper limb nerve cryoneurolysis is non inferior to the usual care and has therapeutic add…
- Conditions
- Hemiplegia, Spasticity, Shoulder Spasticity, Shoulder Stiffness
- Trial name
- spastiCRYO-UL (NCT06782464)
- Testing
- Treatment
- Where
- Luxembourg
- Volunteers
- 50 people
- Sponsor
- Centre National de Rééducation Fonctionnelle et de Réadaptation
Hemiplegia, Post-Ictal
Mirror Therapy in Older Adults Post-stroke
Objective: The present work was carried out to determine the effectiveness of neuromuscular stimulation triggered by mirror therapy in older patients with post-stroke hemiplegia by two different intervention protocols, either…
- Trial name
- NCT04668963
- Testing
- MIRROR THERAPY
- Where
- 2 sites in Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Cerebral Palsy, Spastic
Effect of Task-oriented Circuit Training on Gait Kinematics, Pelvic Symmetry and Endurance in Children With Hemiplegia
Statement of the problem: Does task-oriented circuit training have an effect on kinematic parameters of gait, pelvic symmetry and trunk endurance in children with hemiplegic CP? Purpose of the study: This study aims to…
- Trial name
- NCT04761263
- Testing
- Task-oriented circuit training, Selected Physical therapy program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Horus University
Hemiplegia, Cerebral Palsy
Bimanual Training in Children With Hemiplegia
A randomized control trial of bimanual training in children with hemiplegia. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement…
- Conditions
- Hemiplegia, Cerebral Palsy, Children
- Trial name
- HABIT (NCT01413594)
- Testing
- HABIT
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Teachers College, Columbia University
Stroke, Autonomic Dysfunction
Repetitive Transcranial Magnetic Stimulation in Cardiac Autonomic Dysfunction
The aim of this study is to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) added to conventional neurological rehabilitation on heart rate variability (HRV), quality of life, upper extremity muscle…
- Conditions
- Stroke, Autonomic Dysfunction, Hemiparesis
- Trial name
- NCT07482501
- Testing
- rTMS M1 Motor Cortex Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Afyonkarahisar Health Sciences University
Stroke, Spastic Hemiplegia
Clinical and Ultrasonographic Evaluation of the Efficacy of Extracorporeal Shock Wave Therapy (ESWT) in Post-Stroke Spasticity
This research evaluate the effectiveness of Extracorporeal Shock Wave Therapy (ESWT) for treating spasticity in the wrist flexor muscles (flexor carpi ulnaris - FCU and flexor carpi radialis - FCR) of chronic stroke patients.
- Conditions
- Stroke, Spastic Hemiplegia, Extracorporal Shockwave Therapy (ESWT)
- Trial name
- NCT07119801
- Testing
- Radial Extracorporeal Shock Wave Therapy, Conventional rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Pamukkale University
Stroke
Pediatric Hemiplegia: Synergistic Treatment Using rTMS and CIT
The strategy in rehabilitating pediatric hemiplegia is to overcome "developmental disuse". Disruption of the excitability in the non-stroke hemisphere, with resultant increased excitability (disinhibition) in the stroke…
- Trial name
- NCT01104064
- Testing
- real rTMS combined with constraint induced therapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Minnesota
Stroke, Hemiplegia
Postural Kinesio Taping in Stroke Rehabilitation
Stroke often leads to postural asymmetry and impaired trunk control, which negatively affect mobility, balance, coordination, and activities of daily living.
- Conditions
- Stroke, Hemiplegia, Postural Control
- Trial name
- NCT07334665
- Testing
- Posture-Oriented Kinesio Taping, Standard Rehabilitation
- Volunteers
- 60 people
- Sponsor
- Bursa City Hospital
Virtual Reality, Occupational Therapy
Motivating Occupational Virtual Experiences In Therapy for Kids
A rater-blinded randomized controlled trial (RCT) will be conducted to compare the efficacy of MOVE-IT use in a remotely supervised home exercise program (HEP) to usual care for recovery of upper extremity (UE) function in…
- Trial name
- MOVE-IT (NCT04510857)
- Testing
- MOVE-IT Intervention, UCT Control
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- Barron Associates, Inc.
Stroke
Reaching in Stroke
The project targets stroke survivors to investigate the effect of augmented feedback (using robotic force cues and visual feedback) on their upper limb reaching patterns and trunk compensatory movements.
- Trial name
- NCT02654951
- Testing
- Visual Feedback, Force Feedback
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of British Columbia
Cerebrovascular Accident
Analysis of the Electrical Muscle Activity and Resistance to Movement in Spastic Hemiparetic Patients.
To evaluate and compare the effects of Neuromuscular Electrical Stimulation when applied in the agonist and antagonist muscles of spastic hemiparetic patients.
- Trial name
- EENM (NCT01945151)
- Testing
- Group 2 (G2) NMES is applied in the spastic muscle (gastrocnemius).
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Universidade do Vale do Paraíba
Stroke, Hemiparesis
Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting
Stroke is a leading cause of long-term disability worldwide, with upper-limb impairment representing a major determinant of functional limitation and reduced independence.
- Conditions
- Stroke, Hemiparesis, Upper Extremity Paresis, Motor Impairment
- Trial name
- ROBOHOME (NCT07590349)
- Testing
- Robotic-Assisted Telerehabilitation Virtual Reality-Based Telerehabilitation, Virtual reality-based rehabilitation platform without robotic assistance
- Volunteers
- 70 people
- Sponsor
- University of Campania Luigi Vanvitelli
Cerebral Palsy, Hemiplegia
Functional Benefits of Multisite Upper Limb Surgery in Children With Unilateral Cerebral Palsy (RETRO-CHIRc)
This retrospective study evaluates the functional impact of individualized multisite neuro-orthopedic upper limb surgery in children with unilateral cerebral palsy (hemiplegic CP).
- Trial name
- RETRO-CHIRc (NCT07891078)
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Stroke, Ischemic, Hemiplegia
Evaluation of Noninvasive Vagus Nerve Stimulation on Functional Status in Ischemic Stroke
In this study, the effectiveness of vagus nerve stimulation in patients with right and left hemiparesis will be compared with each other and with the sham application.
- Conditions
- Stroke, Ischemic, Hemiplegia, Hemiparesis;Poststroke/CVA
- Trial name
- NCT05809037
- Testing
- transcutaneous auricular vagus nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Stroke, Hemiplegia
Tele-rehabilitation in the Home With Gaming as a Method of Improving Upper Extremity Function After Stroke
The purpose of the study is to determine whether a novel computer gaming hand exercise regimen would improve hand and arm function and be feasible in people with hemiplegia after Stroke affecting the hand.
- Trial name
- NCT02494362
- Testing
- Computer gaming hand exercise regimen.
- Where
- 2 sites in Canada
- Volunteers
- 15 people
- Sponsor
- University of Manitoba
Stroke, Neuronal Plasticity
Effects of a Computerised Exercise System on Functionality of the Arm,Cognition and Quality of Life in Stroke Patients
Stroke occurs as a result of blood vessels of the brain becoming blocked or bleeding which in turn can result in loss of function in the limbs.
- Conditions
- Stroke, Neuronal Plasticity, Hemiplegia
- Trial name
- NCT04036422
- Testing
- Rejoyce (Rehabilitation Joystick for Computerized Exercise), Conventional physical therapy, Occupational therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Baskent University