Clinical trials: Cerebral Infarct
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
Stroke
Association of Osmotic Drugs With Clinical Outcomes in Acute Large Hemispheric Infarction
Stroke remains the second leading cause of death worldwide, with 2%-8% of these being large hemispheric infarction (LHI) with an occupying effect and the worst prognosis.
- Trial name
- NCT05914272
- Testing
- Osmotic drugs
- Where
- 19 sites in China
- Volunteers
- 2,592 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Stroke, Middle Cerebral Artery With Infarction, Rehabilitation, Upper Limb Recovery, Economic Burdon
Perception About Upper Limb Functional Recovery, Barriers & Use of Training Devices Among Indian Stroke Survivors.
The goal of this observational study is to evaluate perceptions regarding affected arm and hand function and their willingness to use devices to enhance upper limb functions among stroke survivors.
- Trial name
- NCT05894330
- Where
- India
- Volunteers
- 196 people
- Sponsor
- Mahatma Gandhi Institute of Medical Sciences
Cerebral Ischemia
The Effect of Ventilation on Cerebral Oxygenation in the Sitting Position
The aim of this clinical investigation is to determine the effect of intraoperative ventilation on cerebral oxygen saturation in patients undergoing arthroscopic shoulder surgery in the beach chair position (BCP)
- Trial name
- NCT01546636
- Testing
- Hypocapnic group, Normocapnic group
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Endeavor Health
Traumatic Brain Injury, Aneurysmal Subarachnoid Hemorrhage
Monitoring Brain Activity in Human Brain Injury
The outcome of brain injury (physical or stroke) may be related to a brain electrical phenomenon known as Cortical Spreading Depression (CSD). This is a brief cessation of function in a local region of brain tissue.
- Conditions
- Traumatic Brain Injury, Aneurysmal Subarachnoid Hemorrhage, Cerebral Infarction, Cerebral Hemorrhage
- Trial name
- NCT00258505
- Testing
- Procedure: intracranial monitoring up to 9 days after injury
- Where
- 2 sites in Germany, Israel
- Volunteers
- 100 people
- Sponsor
- Soroka University Medical Center
PET/MR, Stroke Ischemic
PET/MR Multimodal Quantitative Analysis of CBF and CMRGlc in Cerebral Ischemia
Research Purpose: This project focuses on clinical research issues in the diagnosis, treatment, and evaluation of patients with cephalic and carotid atherosclerosis.
- Trial name
- PMQIC (NCT07079345)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Subarachnoid Aneurysm Hemorrhage, Cerebral Vasospasm After Subarachnoid Hemorrhage
Delayed Cerebral Infarction Beyond Endoluminal Spasmolysis and Induced Hypertension
An observational study of patients with emerging or established severe cerebral vasospasm after subarachnoid haemorrhage, employing multimodal neuromonitoring.
- Trial name
- Decibel (NCT07305922)
- Testing
- Induced hypertension with norepinephrine, Endoluminal Spasmolysis
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Region Stockholm
Cervical Artery Dissection, Stroke
Looking For Genetic and Environmental Risk Factors and Therapeutic Aspects in Cervical Artery Dissections
The main purpose of this study is to look for genetic and environmental risk factors of cervical artery dissections, a major cause of ischemic stroke in young adults, in a large multicenter case-control trial
- Conditions
- Cervical Artery Dissection, Stroke, Brain Infarction
- Trial name
- CADISP (NCT00657969)
- Where
- 24 sites in Argentina, Belgium and 7 more
- Volunteers
- 4,169 people
- Sponsor
- Cervical Artery Dissections and Ischemic Stroke Patients - Consortium
Type 2 Diabetes, Stroke
The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men
Type 2 diabetes mellitus, T2D is a disease characterized by an immense growing prevalence world wide with an increased risk of myocardial infarction and stroke.
- Conditions
- Type 2 Diabetes, Stroke, Myocardial Infarction
- Trial name
- NCT00256256
- Testing
- glucagon-like-peptide-1
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stroke, Cerebral Infarction
SouthErn China REgisTry for Stroke on Traditional Chinese Medicine
Stroke is the first most common cause of death in China and one of the major causes of functional disability in the adult population.The burden of stoke is significantly increased in China in recent years.
- Conditions
- Stroke, Cerebral Infarction, Transient Ischemic Attack, Cerebral Hemorrhage
- Trial name
- SECRETS-TCM (NCT03380481)
- Testing
- observational only-no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Yefeng Cai
Ischemic Stroke, Migraine
Sensitivity to Acute Cerebral Ischemia in Migrainers
Sensitivity to Acute Middle cerebral or intracranial Carotid artery Occlusion in MIGrainers (SMCO-MIG) is a prospective multi-center study to determine if migraine induces a faster infarct growth as assessed by initial multimodal…
- Conditions
- Ischemic Stroke, Migraine, Migraine With Aura
- Trial name
- SAMCO-MIG (NCT03301441)
- Testing
- questionnaire ef-ID Migraine
- Where
- France
- Volunteers
- 605 people
- Sponsor
- University Hospital, Montpellier
Stroke, Myocardial Infarction
Impact of a Therapeutic Education Program of Patient on the Evolution of the Cardiovascular Chronic Disease
The Exploration Center for Prevention and Treatment of Atherosclerosis (CEPTA, Bordeaux Hospital University) showed that following myocardial infarct (MI) or ischemic stroke (TIA or stroke), the global management (medical and…
- Trial name
- ETHEPAT (NCT02819791)
- Testing
- Optimized conventional therapy alone, Optimized conventional therapy with therapeutic education
- Where
- France
- Volunteers
- 202 people
- Sponsor
- University Hospital, Bordeaux
Cardiovascular Diseases, Heart Diseases
Niacin Plus Statin to Prevent Vascular Events
The purpose of this study is to determine whether raising "good cholesterol" with a drug based on the vitamin niacin, while lowering "bad cholesterol" with a statin drug, can prevent more heart disease than the statin alone.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident, Coronary Disease
- Trial name
- NCT00120289
- Testing
- Extended release niacin, Simvastatin
- Where
- 91 sites in United States, Canada
- Volunteers
- 3,414 people
- Sponsor
- Axio Research. LLC
Stroke, Cardiovascular
Brain and Behavior Correlates of Arm Rehabilitation
This project is designed to use three-dimensional movement analysis and magnetic resonance (fMRI) neuroimaging techniques to examine the brain activity and motor behavior changes associated with constraint-induced (CI) therapy…
- Trial name
- BCAR (NCT04989920)
- Testing
- Experimental group: CIMT group (Constraint-Induced Movement Therapy)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Southern California
Infarction, Brain
CT-Angiography Versus Angiogram as Ancillary Tests in the Determination of Death by Neurologic Criteria
Diagnostic performance of a novel protocol for computed tomography-angiography, as ancillary test in the determination of complete cerebral infarction, in comparison to four vessel angiography.
- Trial name
- Tadaa (NCT07341490)
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Region Stockholm
Acute Ischemic Stroke, Haemorrhagic Stroke
Translational Immunodiagnostics in Stroke (TrImS)
In adult patients presenting to emergency departments within 24 hours of symptom onset with suspected acute stroke, we aim: 1. to identify early brain- and pathology-specific circulating, whole blood, plasma and serum panorOmic…
- Conditions
- Acute Ischemic Stroke, Haemorrhagic Stroke, Transient Ischemic Attacks, Cardioembolic Stroke
- Trial name
- TrImS (NCT05300997)
- Testing
- Biomarker blood draw and saliva collection
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Stroke, Ischemic, Quadrantanopia
Visual Rehabilitation After Occipital Stroke
This research aims to examine changes in plastic potential of the visual system with time from stroke affecting primary visual cortex.
- Conditions
- Stroke, Ischemic, Quadrantanopia, Vision Loss Partial, Visual Field Defect, Peripheral
- Trial name
- NCT04798924
- Testing
- Subacute Training in the intact field, Subacute Training in the blind field, Chronic Training in the blind field
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Rochester
Hemorrhage, Gastrointestinal, Myocardial Infarction
A Study of Channeling in the Use of Nonprescription Paracetamol and Ibuprofen in an Electronic Medical Records Database: Evidence and Implications
The Purpose of this study is to examine whether evidence of channeling exists by analyzing within a cohort of participants with first prescriptions of single-ingredient paracetamol or ibuprofen (or both) whether participants with…
- Conditions
- Hemorrhage, Gastrointestinal, Myocardial Infarction, Stroke, Kidney Diseases
- Trial name
- NCT02830178
- Where
- United States
- Volunteers
- 144,337 people
- Sponsor
- Janssen Research & Development, LLC
Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA)
Pilot Study to Determine the Optimal Protocol for Preoperative Transcutaneous Vagal Neurostimulation
Post-operative atrial fibrillation (POAF) is a frequent complication of surgical aortic valve replacement, affecting 38 to 63% of patients, and increasing risks of stroke, heart failure, and long-term mortality.
- Conditions
- Atrial Fibrillation (AF), Cerebral Vascular Accident (CVA), Heart Failure, Myocardial Infarction (MI)
- Trial name
- VAGASTIMA-PILT (NCT07891390)
- Testing
- tVNS session on the left earlobe
- Where
- 3 sites in France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Lateral Medullary Syndrome, Deglutition Disorders
The Motor Imagery Based on Action Observation Treatment on Dysphagia in Wallenberg Syndrome
The goal of this clinical trial is to learn about on dysphagia in wallenberg syndrome. The main questions it aims to answer are: the efficacy of motor imagery based on action observation treatment in the rehabilitation of…
- Trial name
- NCT06224686
- Testing
- conventional dysphagia treatment, motor imagery based on action observation treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Le Wang
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