Clinical trials: Cerebral Infarct
Unruptured Intracranial Aneurysm, Infarction Cerebral
Chronic Remote Ischemic Conditioning in Small Infarctions Associated with Stent-assisted Coiling of Unruptured Intracranial Aneurysms
1. Disease Description Stent-assisted coiling has become an effective treatment modality for intracranial aneurysms. With continuous advancements in periprocedural antiplatelet regimens, the incidence of symptomatic…
- Trial name
- CRISIS (NCT06826144)
- Testing
- remote ischemic conditioning
- Volunteers
- 84 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Cryptogenic Embolic Stroke, Active Cancer
Identification the Cause of Cerebral Infarction in Patients With Cancer
Although there has been increasing interest in the association between cancer and cerebrovascular disease, the underlying pathophysiology of stroke in cancer patients is still not fully understood.
- Trial name
- NCT02212496
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Samsung Medical Center
Stroke, Small Vessel Cerebrovascular Disease
Small Vessel Disease and Cerebral Infarct Healing InErvation Via Limb Distant Adaptation
Cerebral infarction (ischemic stroke) and cerebral small vessel disease (CSVD) represent major global causes of disability, cognitive decline, and mortality.
- Trial name
- SHIELD (NCT07503301)
- Testing
- Medical-grade ischemic preconditioning training instrument, Standard Treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
CADASIL
The Silent Cortical Infarcts in the Cerebral Amyloid Angiopathy: Is There a Link With Subarachnoid Hemorrhage?
The Cerebral Amyloid angiopathy (CAA) is the leading cause of cortical hemorrhage after 65 years. The presence of cerebral infarction is also reported anatomically in the AAC. MRI studies of these infarcts are rare.
- Trial name
- CAA (NCT02837354)
- Testing
- No intervention
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Inflammatory Arthritis, Rheumatoid Arthritis
The Relationship Between Inflammatory ARTritis and CArdiac DIseAse
The goal of this prospective cohort study is to investigate cardiac comorbidity in a random sample of approximately 1200 patients from a population of outpatients with rheumatoid arthritis and axial spondyloarthritis referred to…
- Conditions
- Inflammatory Arthritis, Rheumatoid Arthritis, Spondylitis, Ankylosing, Axial Spondyloarthritis
- Trial name
- ARTCADIA (NCT05647577)
- Where
- Denmark
- Volunteers
- 1,285 people
- Sponsor
- University Hospital, Gentofte, Copenhagen
Cerebrovascular Accident
JASAP: Japanese Aggrenox Stroke Prevention vs. Aspirin Programme
Phase III study to compare the preventive effect of recurrent brain infarction and safety of Aggrenox (combination drug containing sustained-release dipyridamole 200 mg/acetylsalicylic acid 25 mg) twice daily vs.
- Trial name
- NCT00311402
- Testing
- Aggrenox capsule, Acetylsalicylic Acid (ASA)
- Where
- 151 sites in Japan
- Volunteers
- 1,295 people
- Sponsor
- Boehringer Ingelheim
Leukodystrophy, White Matter Disease
The Myelin Disorders Biorepository Project
The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects.
- Conditions
- Leukodystrophy, White Matter Disease, Leukoencephalopathies, 4H Syndrome
- Trial name
- MDBP (NCT03047369)
- Where
- 23 sites in United States
- Volunteers
- 12,000 people
- Sponsor
- Children's Hospital of Philadelphia
Atrial Fibrillation, Heart Failure
A CALIBER Study: Risk Factors for Stroke, Heart Failure, and Myocardial Infarction in Atrial Fibrillation
We aim to investigate the prognosis of patients diagnosed with AF, particularly in relation to the development of subsequent stroke, heart failure, and myocardial infarction.
- Conditions
- Atrial Fibrillation, Heart Failure, Stroke, Myocardial Infarction
- Trial name
- NCT01944397
- Where
- United Kingdom
- Volunteers
- 125,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Wallenberg Syndrome
Virtual Reality Therapy on Dysphagia in Wallenberg Syndrome
The goal of this clinical trial is to learn about on dysphagia in wallenberg syndrome. The main questions it aims to answer are: the efficacy of Virtual Reality Therapy in the rehabilitation of patients with dysphagia in…
- Trial name
- NCT06328569
- Testing
- Virtual Reality Therapy, Conventional dysphagia treatment
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Myocardial Infarction, Segment Elevation Myocardial Infarction (STEMI)
A 30 Day Study to Evaluate Efficacy and Safety of Pre-hospital vs. In-hospital Initiation of Ticagrelor Therapy in STEMI Patients Planned for Percutaneous Coronary Intervention (PCI)
The aim of this study is to determine whether initiation of ticagrelor as early as in the ambulance setting leads to a rapid reperfusion of the infarct-related artery therefore facilitating the Percutaneous Coronary Intervention…
- Trial name
- ATLANTIC (NCT01347580)
- Testing
- Ticagrelor
- Where
- 96 sites in Algeria, Australia and 11 more
- Volunteers
- 1,875 people
- Sponsor
- AstraZeneca
Aneurysmal Subarachnoid Hemorrhage
The Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage
The purpose of this phase II study is to further assess the safety of tiopronin in aneurysmal subarachnoid hemorrhage(aSAH) patients in order to obtain preliminary data on the efficacy of tiopronin versus placebo in reducing…
- Trial name
- NCT01095731
- Testing
- Tiopronin
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- E. Sander Connolly
Acute Ischemic Stroke
Combined Use of Contact Aspiration and the Stent Retriever Technique Versus Stent Retriever Alone for Recanalisation in Acute Cerebral Infarction
Mechanical thrombectomy (MT) with a stent retriever (SR) device is now the standard intervention in ischemic stroke with large vessel occlusion. Favorable outcome is strongly associated with the successful reperfusion status.
- Trial name
- ASTER2 (NCT03290885)
- Testing
- Combined contact aspiration/Stent Retriever Technique, Stent retriever technique
- Where
- 11 sites in France
- Volunteers
- 408 people
- Sponsor
- Hopital Foch
Stroke, Acute Stroke
Stroke and Cerebrovascular Diseases Registry
This is a single institutional registry database for the patients with stroke and cerebrovascular diseases. Stroke is the fifth leading cause of death in the United States.
- Conditions
- Stroke, Acute Stroke, Acute Brain Injury, Ischemic Stroke
- Trial name
- NCT03281590
- Where
- United States
- Volunteers
- 4,594 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Carotid Artery Stenosis Without Infarction (Disorder), Ischemic Stroke
Brachial Versus Femoral Access for Carotid Artery Stenting
Study purpose: A multicenter, prospective and randomized study is planned to compare the clinical outcomes of carotid artery stenting via brachial artery access and femoral artery access.
- Trial name
- BEFIT (NCT06557135)
- Testing
- Carotid Artery Stenting (CAS)
- Where
- China
- Volunteers
- 235 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Ischemic Stroke
Treatment With Intent to Generate Endovascular Reperfusion
Tigertriever is a CE marked mechanical revascularization device indicated to restore blood flow by removing thrombus from a large intracranial vessel in patients experiencing ischemic stroke within 8 hours of symptom onset.
- Trial name
- TIGER (NCT03474549)
- Testing
- Tigertriever revascularization device
- Where
- 17 sites in United States, Israel
- Volunteers
- 160 people
- Sponsor
- Rapid Medical
Stroke, Cardiovascular Death
A Prospective Multicenter Study to Evaluate Usefulness of Cardio-Ankle Vascular Index in Japan
The objective of this five-year prospective observational follow-up study is to examine the additional benefits of using cardio-ankle vascular index (CAVI) as a predictive indicator of cardiovascular events in high-risk patients.
- Conditions
- Stroke, Cardiovascular Death, Nonfatal Myocardial Infarction
- Trial name
- CAVI-J (NCT01859897)
- Where
- Japan
- Volunteers
- 3,026 people
- Sponsor
- CAVI-J Study Group
Cardiovascular Diseases, Cerebral Infarction
Screening, Early Referral and Lifestyle Tailored E_prescription for Cardiovascular Prevention
We will evaluate an e_Prescription intervention can be integrated into an electronic screening program, which together exploit: (i) reach - the adult population has 100% mobile phone ownership and 92% internet national coverage…
- Conditions
- Cardiovascular Diseases, Cerebral Infarction, Type2 Diabetes Mellitus, Hypertension,Essential
- Trial name
- SELECT (NCT04082091)
- Testing
- SELECT mHealth Program
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Healthy, Coronary Disease
Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study
Cardiovascular disease is a complex multifactorial and polygenic disorder that is thought to result from an interaction between a person's genetic make up and various environmental factors.
- Conditions
- Healthy, Coronary Disease, Myocardial Infarction, Cerebral Infarction
- Trial name
- NCT00262691
- Where
- Japan
- Volunteers
- 7,000 people
- Sponsor
- Nagoya University
Stroke, Brain Infarction
Critical Periods After Stroke Study (CPASS)
To perform an exploratory single center randomized study that will form the basis for a larger scale, more definitive randomized clinical trial to determine the optimal time after stroke for intensive motor training.
- Conditions
- Stroke, Brain Infarction, Brain Ischemia, Cerebral Infarction
- Trial name
- CPASS (NCT02235974)
- Testing
- Early Intensive upper extremity motor training, Sub-acute intensive upper extremity motor training, Chronic intensive upper extremity motor training
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- MedStar National Rehabilitation Network
Acute Cerebrovascular Accident
Effect of Individualized Versus Standard Bp Management During MT for Anterior Ischemic Stroke
DETERMINE is a multicenter, prospective, randomised, open, blinded end-point assessed (PROBE) trial, to evaluate two approaches of blood pressure (BP) management during mechanical thrombectomy for acute ischemic stroke due to an…
- Trial name
- DETERMINE (NCT04352296)
- Testing
- Individualized blood pressure, Standard blood pressure
- Where
- France
- Volunteers
- 433 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
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