Clinical trials: Cerebral Infarct
Stroke, Stroke, Acute
Volumetric Integral Phase-shift Spectroscopy for Noninvasive Detection of Hemispheric Bioimpedance Asymmetry in Acute Brain Pathology
The purpose of this study is to assess the ability of the Fluids Monitor to detect hemispheric bioimpedance asymmetry associated with acute brain pathology in patients presenting with suspected Acute Ischemic Stroke (AIS).
- Conditions
- Stroke, Stroke, Acute, Ischemic Stroke, Hemorrhage
- Trial name
- VITAL (NCT03148340)
- Testing
- VIPS Monitoring
- Where
- 5 sites in United States
- Volunteers
- 287 people
- Sponsor
- Cerebrotech Medical Systems, Inc.
Cerebral Stroke
Facilitating Implicit Learning to Improve Neurorehabilitation in Stroke
Stroke is one of the leading causes of chronic disability in Veterans. Stroke is associated with significant loss of mobility, increased risk of falling, cardiovascular disease, depression and neuro-cognitive impairment.
- Trial name
- NCT02017574
- Testing
- Reaching Task
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Stroke, Acute
Biological Dating of Cerebral Ischemia With GST-π/PRDX1 to Detect Patients With Stroke of Unknown Onset Within the Therapeutic Window of Thrombolysis
The FLAG1 study will assess the diagnostic performance of biomarkers Glutathion S-Transferase-π (GST-π) and Peroxyredoxin 1 (PRDX1) to identify cerebral infarction of less than 4,5 hours in a population of patients with…
- Trial name
- FLAG1 (NCT03364296)
- Testing
- Blood Samples
- Where
- 5 sites in France
- Volunteers
- 935 people
- Sponsor
- Central Hospital, Nancy, France
Cerebrovascular Accident, Transient Ischemic Attack
The Post Stroke Preventive Trial (PREVENT). A RCT Nested in a Cohort Study
Patients with a diagnosis of stroke or TIA, who are already included in the RIALTO-cohort study are asked to participate in a RCT after discharge from hospital.
- Conditions
- Cerebrovascular Accident, Transient Ischemic Attack, Myocardial Infarction
- Trial name
- PREVENT (NCT00253097)
- Testing
- Intervention
- Where
- 2 sites in Denmark
- Volunteers
- 353 people
- Sponsor
- Hvidovre University Hospital
Cerebral Ischemia
Impact of Interscalene Nerve Block on Cerebral Perfusion During Surgery in the Beachchair Position
Beachchair position is used by many orthopaedic surgeons for shoulder surgery. Most patients undergoing surgery in this position have no complications.
- Trial name
- NCT01983618
- Testing
- Interscalene nerve block and catheter, Interscalene catheter
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Ischemic Stroke, Acute
Thrombolysis and Deferoxamine in Middle Cerebral Artery Occlusion
Iron overload has been associated with greater brain injury in ischemia/reperfusion experimental stroke models and ischemic stroke patients, especially in those treated with thrombolytic treatment.
- Trial name
- TANDEM-1 (NCT00777140)
- Testing
- Deferoxamine
- Where
- 4 sites in Spain
- Volunteers
- 62 people
- Sponsor
- Germans Trias i Pujol Hospital
Stroke, Acute Ischemic Stroke
The Feasibility and Safety of RK-4 Injection Bypassing Blood-brain Barrier in the Treatment of Acute Large Hemispheric Infarction Using Intracalvariosseous Injection Device
A pilot study confirmed the feasibility and safety of neuroprotectant RK-4 intracalvariosseous(ICO) injection in patients with malignant middle cerebral artery infarction (mMCAI), showing a trend in improving 90-day functional…
- Conditions
- Stroke, Acute Ischemic Stroke, Blood-Brain Barrier
- Trial name
- SOLUTION-ICD (NCT07514949)
- Testing
- RK-4 ICO injection, Conventional treatment
- Where
- China
- Volunteers
- 6 people
- Sponsor
- yilong Wang
Subarachnoid Hemorrhage, Pneumonia, Bacterial
Influence of Pneumonia on Delayed Cerebral Ischemia After Subarachnoid Hemorrhage . SAH-CIP (SubArrachnoid Hemorrhage - Cerebral Infarction Pneumonia)
Prognosis of subarachnoid hemorrhage (SAH) is scarce, indeed almost half patients die or become severely disable after SAH. Outcome is related to the severity of the initial bleeding and delayed cerebral infarction (DCI).
- Trial name
- SAH-CIP (NCT05094349)
- Where
- France
- Volunteers
- 224 people
- Sponsor
- University Hospital, Brest
Hemorrhage, Gastrointestinal, Myocardial Infarction
A Study of Channeling in the Use of Nonprescription Paracetamol and Ibuprofen in an Electronic Medical Records Database: Evidence and Implications
The Purpose of this study is to examine whether evidence of channeling exists by analyzing within a cohort of participants with first prescriptions of single-ingredient paracetamol or ibuprofen (or both) whether participants with…
- Conditions
- Hemorrhage, Gastrointestinal, Myocardial Infarction, Stroke, Kidney Diseases
- Trial name
- NCT02830178
- Where
- United States
- Volunteers
- 144,337 people
- Sponsor
- Janssen Research & Development, LLC
Healthy
Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- SYNAPSE (NCT00766584)
- Testing
- Sleep apnea/hypopnea detection
- Where
- France
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Healthy
Evaluation of Aging, Autonomic Nervous System Activity and Cardiovascular Events
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- PROOF (NCT00759304)
- Where
- France
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Moyamoya Disease, Ischemic Cerebral Infarction
NBP in Patients With Moyamoya Disease of High Risk for Ischemic Cerebrovascular Events
An extracranial-to-intracranial (EC-IC) revascularization is the most widely used treatment to improve cerebral perfusion in patients with moyamoya disease (MMD), and it has been shown to reduce the risk of subsequent stroke and…
- Conditions
- Moyamoya Disease, Ischemic Cerebral Infarction, Ischemic Stroke, Ischemic Cerebrovascular Accident
- Trial name
- NICE-MMD (NCT04205578)
- Testing
- dl-3-n-butylphthalide (NBP), Normal Saline 0.9% Infusion Solution
- Where
- 2 sites in China
- Volunteers
- 450 people
- Sponsor
- yuanli Zhao
Acute Ischemic Stroke, Physical Activity
Physical Activity Immediately After Acute Cerebral Ischemia
Stroke is the leading cause of adult disability in Europe and United States and the second leading cause of death worldwide and affects more than 10,000 Danes each year.
- Conditions
- Acute Ischemic Stroke, Physical Activity, Accelerometer
- Trial name
- NCT01594190
- Testing
- physical activity 15 minutes/day, physical activity, 2 x 30 minutes/day
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Hillerod Hospital, Denmark
Brain Infarction
Flying Intervention Team for Endovascular Treatment of Acute Ischemic Stroke in Rural Areas
The aim of this study is to compare time delay and safety parameters of stroke patients initially admitted to a rural primary stroke center (PSC) who receive endovascular treatment (EVT) by a Flying Intervention Team with…
- Trial name
- FIT (NCT04270513)
- Testing
- Endovascular treatment by Flying Intervention Team
- Where
- Germany
- Volunteers
- 477 people
- Sponsor
- Munich Municipal Hospital
Stroke With Hemiparesis
Transfer of Grasp Control Across Hands After Stroke
The purpose of this study is to examine if the strong hand can assist in the recovery of muscle function in the weak hand after a stroke.
- Trial name
- NCT00589368
- Testing
- Transfer of grasp control across hands
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stroke, Cerebral Palsy
Modulation of Brain Plasticity After Perinatal Stroke
Newborn stroke is the leading cause of a common type of cerebral palsy (CP) that affects thousands of Canadian children and families.
- Trial name
- PLASTIC CHAMPS (NCT01189058)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Constraint-induced movement therapy (CIMT)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Intracerebral Haemorrhage, Paediatric Stroke
Master Study Protocol for the Cohort of the Specialist Network Stroke (SN Stroke)(Stroke-CORE)
The Stroke-CORE cohort aims to provide a comprehensive and up-to-date understanding of stroke care in Germany. To achieve this, patients are followed along the entire continuum of care-from initial management before hospital…
- Conditions
- Intracerebral Haemorrhage, Paediatric Stroke, Stroke Acute, Stroke
- Trial name
- Stroke-CORE (NCT07553650)
- Where
- 12 sites in Germany
- Volunteers
- 12,750 people
- Sponsor
- Charite University, Berlin, Germany
Cerebral Infarction, Cerebral Hemorrhage
Life After STroke - the LAST Study
The LAST study is a Norwegian multi site randomised controlled trial that intends to assess the effect of a long term follow up program after stroke.
- Trial name
- LAST (NCT01467206)
- Testing
- Long term follow up by a coordinating physiotherapist, Standard care
- Where
- 2 sites in Norway
- Volunteers
- 380 people
- Sponsor
- Norwegian University of Science and Technology
Brain Infarction, Ischemic Stroke
Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome
BACKGROUND: In industrialized countries a considerable and increasing proportion of strokes occur at younger ages. Stroke at young age causes marked disability at worst and thus long-standing socioeconomic consequences and…
- Conditions
- Brain Infarction, Ischemic Stroke, Thrombosis, Foramen Ovale, Patent
- Trial name
- SECRETO (NCT01934725)
- Where
- 19 sites in Estonia, Finland and 11 more
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- SECRETO Study Consortium
End Stage Renal Disease, Cardio-Renal Syndrome
Cardio-Renal Registry
Cardiovascular disease is the leading cause of morbidity and mortality among patients with chronic kidney disease (CKD). Even after adjustment for known cardiovascular risk factors, including diabetes and hypertension, mortality…
- Conditions
- End Stage Renal Disease, Cardio-Renal Syndrome, Myocardial Infarction, Cerebrovascular Accident
- Trial name
- BHCRR (NCT06521801)
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 60,000 people
- Sponsor
- Queen Mary University of London
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