Clinical trials: Cerebral Oxygen Saturation
Cardiac Surgical Procedures, High-risk Surgical Patient
A New Non-invasive Marker to Detect Silent Hypoxia in Patients Undergoing Cardiac Surgery
In patients undergoing cardiac surgery under cardiopulmonary bypass, some organs like brain and heart are preserved while others (skin, gut and skeletal muscle) are being underperfused.
- Conditions
- Cardiac Surgical Procedures, High-risk Surgical Patient, Anaerobic Threshold
- Trial name
- NCT01560611
- Testing
- Near infrared spectroscopy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Oxygen Saturation
Comparison of Volatile Anesthetics on Cerebral Oxygenation During Controlled Hypotension
Controlled hypotension is a preferred method for reducing surgical bleeding during septoplasty operations however, the level of hypotension and bradycardia should not disrupt cerebral oxygenation.
- Trial name
- NCT02834845
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Ufuk University
Pediatric Liver Transplantation, Developmental Delay
Intraoperative Cerebral and Renal Tissue Oxygen Saturation and Pediatric Living Donor Liver Transplantation Prognosis.
This rSO2 study is a prospective clinical study. The purpose of the rSO2 study is to investigate whether there is a correlation between the intraoperative cerebral and renal tissue oxygen saturation and the incidence of…
- Conditions
- Pediatric Liver Transplantation, Developmental Delay, Postoperative Complications, Socioemotional Delay
- Trial name
- rSO2-LDLT (NCT04518332)
- Where
- China
- Volunteers
- 123 people
- Sponsor
- RenJi Hospital
Cerebral Oxygen Saturation
Changes of Cerebral Oxygenation During Anesthesia Induction
The aim of this study was to investigate the changes of cerebral oxygen saturation (rSO2) during anesthesia induction.
- Trial name
- NCT02687334
- Testing
- 100% Oxygen
- Where
- China
- Volunteers
- 33 people
- Sponsor
- China Medical University, China
Hypoxia, Hypotension
Vasopressors for Cerebral Oxygenation
Liberal fluid administration is one of risk factors of developing acute lung injury (ALI) in thoracic surgery. Therefore, the investigators try to restrain fluid administration, and in the case of intraoperative hypotension, the…
- Trial name
- NCT02009007
- Testing
- dopamine, phenylephrine
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Samsung Medical Center
Obstructive Sleep Apnea
Vasoactive Hormones and Oxygen Saturation During Apneic Events in Patients With Obstructive Sleep Apnea
The mechanisms involved in development and maintenance of hypertension in obstructive sleep apnea are not clarified. We hypothesize that patients with obstructive sleep apnea have an abnormal level of some vasoactive hormones…
- Trial name
- NCT00438412
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Impaired Oxygen Delivery, Cerebral Hypoxia
The Impact of a Beach Chair Position During Shoulder Arthroscopy on Regional Cerebral Oxygen Saturation : Comparison of Interscalene Block and General Anesthesia
The aim of this study is to investigate the relationship between the patient positioning in the beach chair position with consequential arterial pressure changes and their influence on regional cerebral oxygen saturation under…
- Trial name
- NCT02605005
- Volunteers
- 60 people
- Sponsor
- Osijek University Hospital
Cerebral Oxygen Saturation, Postoperative Cognitive Function
Effect of Cerebral Oxygen Saturation Monitoring on POCD of Elderly Patients Undergoing Shoulder Arthroscopy
To observe whether adjusting the level of intraoperative controlled hypotension through cerebral oxygen saturation monitoring can improve postoperative cognitive function(POCD) and reduce postoperative neurological complications…
- Trial name
- NCT05615480
- Testing
- Controlled hypotension guided by cerebral oxygen saturation monitoring
- Volunteers
- 400 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Cerebral Oxygen Saturation During Spinal Anesthesia for Cesarean Delivery
Spinal Anesthesia for Cesarean Delivery is Associated With Decreases in Regional Cerebral Oxygen Saturation as Assessed by Near- Infrared Spectroscopy
The cerebral oxygen saturation is assessed by means of near-infrared spectometry in parturients undergoing cesarean delivery under spinal anesthesia.
- Trial name
- NCT01669135
- Testing
- Spinal Anesthesia with cerebral oxygen saturation monitoring
- Where
- Greece
- Volunteers
- 34 people
- Sponsor
- University of Athens
Anesthesia
Mannitol Improves Cerebral Oxygen Saturation
Decreased cerebral oxygen saturation (rSO2) was reported to occur during insufflation for laparoscopic procedures due to increased Intracranial pressure (ICP) with resultant decrease in cerebral perfusion pressure.
- Trial name
- NCT02091180
- Testing
- Mannitol, Control
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Cerebral Oxygen Saturation
The Effect of Vasopressors on Cerebral Oxygentaion During Off Pump CABG
The purpose of this study is to analyze the changes in cerebral oxygen saturation during the use of three vasopressors, phenylephrine, norepinephrine, and vasopressin, which are currently used during coronary artery bypass…
- Trial name
- NCT04214145
- Testing
- Phenylephrine, Norepinephrine, Vasopressin
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Seoul National University Hospital
Prematurity; Extreme
Use of NIRS in Preterm Population Born at Altitude
Near-infrared spectroscopy (NIRS), is a technology that can provide continuous, non-invasive monitoring of oxygenation in tissue.
- Trial name
- NCT04639583
- Testing
- Near-infrared spectroscopy (NIRS) utilization
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of New Mexico
Disorder of Hip Joint
Cerebral Oximetry and Anesthetic Technique
The purpose of the study is to compare the effects of spinal and general anesthesia on transcranial regional cerebral oxygen saturation in geriatric patients undergoing total hip arthroplasty.
- Trial name
- NCT03349658
- Testing
- general anesthesia, spinal anesthesia
- Volunteers
- 82 people
- Sponsor
- Antalya Training and Research Hospital
Carotid Stenosis, Carotid Artery Diseases
Cerebral Oximetry During Awake Carotid Endarterectomy
Surgery to remove plaque from the carotid artery in the neck requires the artery to be clamped for a period of time. In some patients this reduces blood flow to the brain enough to cause temporary symptoms, and a temporary…
- Conditions
- Carotid Stenosis, Carotid Artery Diseases, Brain Ischemia, Carotid Endarterectomy
- Trial name
- COACE (NCT07816081)
- Testing
- Masked continuous cerebral oximetry, Standardised awake neurological test, Serial cognitive assessment
- Where
- Vietnam
- Volunteers
- 150 people
- Sponsor
- Nguyen Toan Thang
Postoperative Delirium, Cerebral Oxygen Saturation
Effect of Perioperative IV Ibuprofen on Cerebral Oxygenation and Postoperative Cognition During One-Lung Ventilation
This study compares the effects of ibuprofen administered during surgery and within the first 24 hours after surgery, versus no ibuprofen, on cerebral oxygenation, postoperative changes in consciousness (postoperative delirium…
- Conditions
- Postoperative Delirium, Cerebral Oxygen Saturation, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- NCT07399184
- Testing
- ibuprofen
- Volunteers
- 54 people
- Sponsor
- Ondokuz Mayıs University
Cerebral Ischemia
Correlation of Cerebral Oxygen Saturation Measured From 2 Sensor Sites: Forehead vs. Temporal
Cardiac surgery and neurosurgery may decrease cerebral blood flow leading to cerebral dysfunction. Regional cerebral oxygen saturation (rScO2) monitor via Near-infrared spectometry (NIRS) is recommended for early detection and…
- Trial name
- NCT05087836
- Testing
- Sensor at forehead area, Sensor at temporal area
- Where
- Thailand
- Volunteers
- 21 people
- Sponsor
- Khon Kaen University
Cerebral Oxygenation
Effect of Left Paratracheal Pressure on Cerebral Oxygenation During General Anesthesia
Left paratracheal pressure (LPP) has been proposed as an alternative to cricoid pressure to reduce the risk of regurgitation during induction of general anesthesia.
- Trial name
- PARANIRS (NCT07778303)
- Testing
- Left Paratracheal Pressure, Cricoid Pressure
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Clinique Saint-Luc
Rotator Cuff Tear Arthropathy
Vasopressin to Prevent Hypotension During Beach Chair Surgery
Patients undergoing surgery in beach chair position (BCP) are at risk for cerebral ischaemia. The impacts of arginine vasopressin (AVP) on haemodynamics and cerebral oxygenation are evaluated during surgery in BCP.
- Trial name
- NCT01687894
- Testing
- Vasopressins, propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Chonnam National University Hospital
Depression
Hyperventilation Combined With Etomidate or Ketamine Anesthesia in ECT Treatment of Major Depression
This is a randomized controlled study assessing the effect of pre-emptive hyperventilation on ECT seizure duration, cerebral desaturation and remission of depressive symptoms in patients with Major Depressive Disorder.
- Trial name
- NCT02924090
- Testing
- Etomidate, Ketamine, Hyperventilation
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- University of Manitoba
Apnea+Hypopnea, Tracheal Dilatation
Tracheal Dilatation in Pediatric Patients With Acquired Tracheal Stenosis, and the Effects of Apneic Oxygenation
The study presents an alternative method of tracheal dilatation in pediatric patients with acquired tracheal stenosis. Dilatation is performed by the use of balloon catheter connected with manometer, that is bronchoscopic guided…
- Conditions
- Apnea+Hypopnea, Tracheal Dilatation, Igel, Tracheal Stenosis
- Trial name
- NCT05028023
- Testing
- Apneic oxygenation - supplemental high flow oxygen administration by an apneic way
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- Aristotle University Of Thessaloniki