Clinical trials: Cerebral Oxygenation
Critical Illness
Brain Oxygenation During Prehospital Anesthesia
The study will evaluate the feasibility of Nonin SenSmart H500 device to measuring brain oxygenation during prehospital anesthesia of adult patient.
- Trial name
- BOPRA-P (NCT03948711)
- Testing
- Near-infrared spectroscopy (NIRS) monitoring of cerebral oxygenation
- Where
- 2 sites in Finland
- Volunteers
- 100 people
- Sponsor
- Helsinki University Central Hospital
Hypotension; Controlled, Cognitive Dysfunction
Changes in Cerebral Oxygenation and Cognitive Functions
The present study aimed to assess the influence of nitroglycerin and esmolol-induced hypotension on cerebral oxygen saturation by using near-infrared spectroscopy and postoperative cognitive function in patients undergoing nasal…
- Trial name
- NCT04948957
- Testing
- Esmolol, Nitroglycerin
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Congenital Disorders, Cerebral Desaturation
International Study of Cerebral Oxygenation and Electrical Activity During Major Neonatal Surgery
The goal of this observational study is to determine the incidence of perioperative cerebral desaturation in neonates undergoing surgery for congenital malformations. The main questions it aims to answer are: 1.
- Conditions
- Congenital Disorders, Cerebral Desaturation, Neonatal Surgery
- Trial name
- NCT05673499
- Testing
- NIRS/EEG monitoring
- Where
- 15 sites in United States, Australia and 5 more
- Volunteers
- 900 people
- Sponsor
- Children's Hospital of Philadelphia
Coronary Artery Disease, Heart Valve Disease
A Prospective Study With a New Device for the Monitoring of Cerebral Oxygenation on Cardiac Surgery Patients
The purpose of this study is to determine whether a new cerebral oxygenation monitoring device is comparatively similar to the current approved devices.
- Trial name
- NCT00598936
- Testing
- CDI 1000 COM and INVOS 5100
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of California, Irvine
Cardiac Catheterization
Validation of Brain Oxygenation Monitor on Pediatric Patients
The aim of this study is calibrate (adjust and tune) the CAS FORE-SIGHT Near-Infrared Spectroscopy (NIRS) monitor when used to measure the tissue oxygen saturation of internal organs (StO2).
- Trial name
- NCT00849940
- Testing
- CAS NIRS FORE-SIGHT oximeter
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Duke University
Cerebral Ischemia
Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation
During clamping of one internal carotid artery for endarterectomy, blood flow through this vessel has to be compensated by collateral arteries including the contralateral internal artery and vertebral arteries.
- Trial name
- NIRSMED (NCT01311414)
- Testing
- cafedrine/theodrenaline, urapidil
- Where
- Germany
- Sponsor
- University Hospital Schleswig-Holstein
Cerebral Oxygenation and Blood Flow in Tobacco Use Disorder
Investigation of Brain Oxygenation and Blood Flow in Smokers
Cerebral oxygenation and blood flow in tobacco use disorder and their relation to smoking abstinence will be measured with MRI" ändern in "Cerebral oxygenation and blood flow in tobacco use disorder
- Trial name
- OEF (NCT03571243)
- Testing
- no intervention
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Post-Hemorrhagic Hydrocephalus
Cerebral Perfusion, Oxygenation, Electrical Activity
The specific aim of the research proposal in preterm infants with IVH and PHH who require placement of an Omaya reservoir or a shunt is to determine if decreasing ventricular volume improves, middle cerebral artery flow, cerebral…
- Trial name
- NCT00747682
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Cardiac Arrest, Out-Of-Hospital
Brain Oxygenation During Cardiopulmonary Resuscitation
The study is aimed to assess (a) the incidence of hyperoxia at the point of return of spontaneous circulation (ROSC) and (b) the role of arterial blood oxygen partial pressure to brain oxygenation during out-of-hospital cardiac…
- Trial name
- NCT03464123
- Testing
- Standard cardiopulmonary resuscitation
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Ruptured Cerebral Aneurysm
Effect of Propofol Midazolam on Cerebral Oxygenation and Metabolism During Clipping of Ruptured Cerebral Aneurysm
Despite the theoretical benefits of i.v. agents, volatile agents remain popular. In a study comparing desflurane, isoflurane, and sevoflurane in a porcine model of intracranial hypertension, at equipotent doses and normocapnia…
- Trial name
- NCT03778723
- Testing
- Total intravenous anesthesia (TIVA), Inhalation Anesthesia, Rescue fentanyl
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Cerebral Oxygenation
Effect of Left Paratracheal Pressure on Cerebral Oxygenation During General Anesthesia
Left paratracheal pressure (LPP) has been proposed as an alternative to cricoid pressure to reduce the risk of regurgitation during induction of general anesthesia.
- Trial name
- PARANIRS (NCT07778303)
- Testing
- Left Paratracheal Pressure, Cricoid Pressure
- Where
- Belgium
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Clinique Saint-Luc
Premature Birth
EEG and NIRS in Preterm Infants
Experimental cross-sectional study of a single application (vojta therapy or massage) in preterm and non-preterm infants to test whether there are differences in brain activation and oxygenation that occur with both techniques…
- Trial name
- NCT05410340
- Testing
- Vojta Therapy, Massotherapy
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Salamanca