Clinical trials: Cerebral Oxygenation
Stroke
The Relationship Between Motor Cortex Oxygenation and Motor Function Recovery in Stroke Patients
Stroke is the most common cause of motor function impairment. However, the functional impairment is not totally irreversible. Several mechanisms may involved in both the cortical and motor function recovery after onset of stroke…
- Trial name
- NCT01781689
- Testing
- Functional Electric Stimulation, Rehabilitation programs
- Where
- Taiwan
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Veterans General Hospital.
Head Injury Trauma, Hyperventilation
Hyperventilation in Patients With Traumatic Brain Injury
Elevated intracranial pressure is a dangerous and potentially fatal complication after traumatic brain injury. Hyperventilation is a medical intervention to reduce elevated intracranial pressure by inducing cerebral…
- Trial name
- NCT03822026
- Testing
- Hyperventilation test
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University of Zurich
Neonatal Respiratory Distress
Tolerance of nHFPV Versus nCPAP in Neonatal Respiratory Distress
Respiratory distress is the main cause of morbimortality in preterm and term neonates. In most of the case, these babies required the use of positive end expiratory pressure (PEEP) delivered by a non invasive device.
- Trial name
- TONIPEP (NCT02030691)
- Testing
- Nasal continuous airway positive pressure (nCPAP), Nasal high frequency percussive ventilation (nHFPV)
- Where
- France
- Volunteers
- 49 people
- Sponsor
- University Hospital, Bordeaux
Tissue Oxygenation Measurement
OxyPrem Validation Study
The precision of the novel diagnostic near-infrared spectroscopy (NIRS) device for the measurement of tissue oxygenation and hemoglobin concentration (OxyPrem) is assessed by repeated measurements.
- Trial name
- NCT04860401
- Testing
- Measurement of tissue oxygenation with novel diagnostic near-infrared spectroscopy device (OxyPrem) (no clinical decisions based on oxygenation levels)
- Where
- Switzerland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Hans Ulrich Bucher
Cardiogenic Shock, Extracorporeal Life Support
Post-Surgery Extracorporeal Life Support
Extracorporeal Life Support (ECLS) may provide pulmonary and circulatory support for patients with acute heart failure refractory to conventional medical therapy.
- Conditions
- Cardiogenic Shock, Extracorporeal Life Support, Extracorporeal Membrane Oxygenation Complication, Post Cardiac Arrest Syndrome
- Trial name
- PC-ECLS (NCT04330651)
- Testing
- ECLS
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- University of Florence
Cerebral Ischemia
Total Shoulder Arthroplasty Near-infrared Spectroscopy
The purpose of this study is to measure cerebral oxygenation and cardiac output of total shoulder replacement patients undergoing general anesthesia (GA) and positive-pressure ventilation (PPV).
- Trial name
- TSA NIRS (NCT02198183)
- Testing
- Casmed Fore-Sight Elite, Non-invasive Cardiac Output Monitor (NICOM)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Hospital for Special Surgery, New York
Nutrition Disorder, Infant, Music
Lullaby and Classic Music's Effect on Vital Findings and Comfort
In the study, lullabies and classical music played to preterm babies during orogastric tube feeding; It will be tried to determine the effect on cerebral oxygenation level, vital signs and comfort levels.
- Conditions
- Nutrition Disorder, Infant, Music, Preterm, Vital Signs
- Trial name
- NCT05333575
- Testing
- Lullaby, Classic music
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Septic Shock
Cerebral Hemodynamics and Oxygenation in Critically Ill Patients
Critically-ill patients frequently experience marked changes in mean arterial pressure and carbon dioxide partial arterial pressure, the two major determinants of the cerebral blood flow.
- Trial name
- NCT04690530
- Testing
- mechanical ventilation, Sedation
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nice
Delirium - Postoperative, Cerebral Oxygenation
Cerebral Oxygen Consumption Response to Increased Oxygen Supply and Postoperative Delirium in Older Surgical Patients
The goal of this observational study is to learn whether the brain's ability to use oxygen during surgery is associated with postoperative delirium in adults aged 65 years and older undergoing general anesthesia.
- Trial name
- NCT07463586
- Testing
- Intraoperative Cerebral Oxygen Utilization Assessment
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Bundang Hospital
Cerebral Oxygenation, Peripheric Oxygenation
The Measurement Of Cerebral Oxygenisation With NIRS Method İn Polycythaemic Infants Might Add A Criterion To Indicate PPET?
Near infrared spectrophotometry (NIRS) offers the possibility of noninvasive and continuous bedside investigation of cerebral , renal, mesenteric and peripheric oxygenation and hemodynamics, and changes in newborn period.The aim…
- Conditions
- Cerebral Oxygenation, Peripheric Oxygenation, Polycythaemic Infants
- Trial name
- NCT01255618
- Testing
- INVOS 5100
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Zekai Tahir Burak Women's Health Research and Education Hospital
Respiratory Insufficiency
Effect of Non-invasive Ventilation (NIV) on Cerebral Oxygenation
SUMMARY AND AIM Background: The proper management of brain oxygenation is an essential component of all anaesthesiologic procedures.
- Trial name
- NCT02454582
- Testing
- Somanetics INVOS Cerebral Oxymeter 5100C
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ass.-Prof. PD Dr. Klaus Ulrich Klein
Parkinson Disease, Neurogenic Orthostatic Hypotension
Brain Perfusion & Oxygenation in Parkinson's Disease With NOH
This is a double blind placebo controlled trial in Parkinson's disease (PD) patients with neurogenic orthostatic hypotension (NOH).
- Trial name
- NCT03229174
- Testing
- Droxidopa
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- William Ondo, MD
Airway Reactivity, Hemodynamic Stability During Anesthesia
ETCO₂ Targeting and Cerebral Oxygenation
This study looked at a safer way to prepare patients for anesthesia before major spinal surgery. Instead of using advanced or complex oxygen devices, the approach will use standard oxygen methods, guided by the patient's…
- Trial name
- NCT07526077
- Testing
- regional cerebral oxygen saturation
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- Prince Sultan Military Medical City
Supratentorial Brain Tumor Surgery
Cerebral Oxygenation and Metabolism After Reversal Of Rocuronium: Comparison Between Sugammadex Versus Neostigmine
Cholinesterase inhibitors such as Neostigmine and Edrophonium have been used to reverse neuromuscular blockade after surgery. However, these drugs have a relatively slow onset and have adverse effects associated with stimulation…
- Trial name
- NCT02944175
- Testing
- Sugammadex, Neostigmine
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Oxygen Supplementation on Cerebral Oxygenation, Symptoms and Performance During STST in COPD Patients
It is a randomised, single-blind trial of the effect of acute oxygen supplementation on cerebral oxygenation during the 30 sec Sit-To-Stand Test (STST) in chronic obstructive pulmonary disease patients, without resting hypoxemia.
- Trial name
- NCT07024914
- Testing
- Oxygen, medical air
- Where
- Greece
- Volunteers
- 25 people
- Sponsor
- George Papanicolaou Hospital
Anesthesia, Anesthesia; Reaction
Individual Cerebral Hemodynamic Oxygenation Relationships
This is a randomized controlled trial in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two…
- Trial name
- ICHOR (NCT04435834)
- Testing
- Propofol or Sevoflurane
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Matthew Borzage
Heart Valve Diseases
Normothermiс Cardiopulmonary Bypass Increases Cerebral Oxygenation During Valve Surgery
The aim of our study was to evaluate the effect of different temperature regimens of cardiopulmonary bypass on systemic oxygen transport and cerebral oxygenation during surgical correction of acquired heart diseases.
- Trial name
- NCT01685554
- Testing
- hypothermic CPB, normothermic CPB
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- Northern State Medical University
Metabolic Syndrome, Coronary Artery Disease
Brain, Cardiac Hemodynamics and Cognition During Exercise in Subjects With Various Cardiovascular Profiles
People with cardiovascular risk (CV) factors (obesity, diabetes, etc...) or established heart disease (such as coronary heart disease or chronic heart failure) often have cognitive dysfunction as compared to people without CV…
- Conditions
- Metabolic Syndrome, Coronary Artery Disease, Heart Failure
- Trial name
- COGNEX (NCT03018561)
- Testing
- Exercise and Cognitive testing
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Cardiac Arrest, Out-Of-Hospital
Brain Oxygenation During Cardiopulmonary Resuscitation
The study is aimed to assess (a) the incidence of hyperoxia at the point of return of spontaneous circulation (ROSC) and (b) the role of arterial blood oxygen partial pressure to brain oxygenation during out-of-hospital cardiac…
- Trial name
- NCT03464123
- Testing
- Standard cardiopulmonary resuscitation
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Carotid Thrombendarterectomy, Cerebral Oxygenation
Cerebral Oximetry for Carotid EEA
Aim oft he study is to compare two different devices for cerebral oximetry (FORE-SIGHTTM Monitor (CAS Medical Systems, Branford, Connecticut, USA and INVOSTM Somanetics, Troy, Michigan, USA) in patients undergoing surgical…
- Conditions
- Carotid Thrombendarterectomy, Cerebral Oxygenation, NIRS, Regional Anesthesia
- Trial name
- NCT02203370
- Testing
- NIRS - Near-infrared spectroscopy
- Where
- Austria
- Volunteers
- 126 people
- Sponsor
- Salzburger Landeskliniken