Clinical trials: Cerebral Vascular Accident
Chronic Stroke
ANIMATOR - RehUP BCI Controlled Robotic Therapy vs. an Attention-based Control
ANIMATOR aims to examine how BCI therapy vs. attention based control therapy can be used to treat people in the chronic phase of stroke with moderate to severe upper extremity impairment.
- Trial name
- ANIMATOR (NCT06538506)
- Testing
- RehUp BCI Intervention, Control Therapy
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Calgary
Ischemic Stroke
Ginsenoside-Rd for Acute Ischemic Stroke
The purpose of this study is to evaluate the efficacy and safety of ginsenoside-Rd for acute ischemic stroke.
- Trial name
- NCT00591084
- Testing
- ginsenoside-Rd 10 mg, ginsenoside-Rd 20mg
- Where
- China
- Volunteers
- 199 people
- Sponsor
- Xijing Hospital
Tachycardia, Atrial Fibrillation
Observation of Clinical Routine Care for Patients With BIOTRONIK Implantable Cardiac Monitors (ICMs)
This registry is performed for the long-term assessment of outcome, performance and residual safety aspects of the BIOMONITOR III and possible successors in a real-life clinical set-up.
- Conditions
- Tachycardia, Atrial Fibrillation, Syncope, Bradycardia
- Trial name
- BIOSTREAM-ICM (NCT04075084)
- Where
- 31 sites in Australia, Czechia and 7 more
- Volunteers
- 1,400 people
- Sponsor
- Biotronik SE & Co. KG
Stroke Sequelae
Balance Systems Protocol for Subacute Phase Stroke Patients.
The aim of the study is to evaluate if the application of a protocol focused on the equilibrium systems versus the conventional treatments decreases the time to acquire equilibrium in standing, the risk of falls and favors the…
- Trial name
- BSPStroke (NCT03406026)
- Testing
- Balance System Protocol Stroke, Control Stroke
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Universitat Internacional de Catalunya
Acute Ischemic Stroke, Stroke, Acute
Xingnaojing for Mild-to-severe Acute Ischemic Stroke
The main purpose of this trial is to determine whether Xingnaojing, intravenously administered within 24 hours of symptom onset, improves the daily living ability of acute ischemic stroke at 90 days.
- Conditions
- Acute Ischemic Stroke, Stroke, Acute, Stroke, Ischemic
- Trial name
- XMAS-2 (NCT04150835)
- Testing
- Xingnaojing injection, Standard care
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Dongzhimen Hospital, Beijing
Non-paroxysmal Atrial Fibrillation
LAA Clipping Versus NOACs to Prevent Stroke in Non-paroxysmal Atrial Fibrillation.
This trial is designed to examine the hypothesis that thoracoscopic LAA clipping is superior to NOACs for stroke, systemic embolism, all-cause mortality, major bleeding events and clinically relevant nonmajor bleeding events in…
- Trial name
- NCT06021808
- Testing
- Thoracoscopic LAA clipping, Novel oral anticoagulant
- Where
- China
- Volunteers
- 290 people
- Sponsor
- China National Center for Cardiovascular Diseases
Stroke
Robot-assisted Hand Rehabilitation for Patients With Stroke
Robotic therapy can deliver larger amounts of upper extremity movement practice for stroke rehabilitation. Although the treatment effects were supported in studies, there are still limitations in clinical intervention.
- Trial name
- NCT03392493
- Testing
- Robot-assisted hand rehabilitation, Standard treatment
- Where
- Taiwan
- Volunteers
- 25 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Stroke
Qualitative Analysis of Interviews Between Pharmacist and Elderly Patients Treated with Antithrombotics for an Ischemic Stroke.
Cerebrovascular accident is the 2nd leading cause of death and the leading cause of disability in the world. There are brakes and levers of medication adherence in the context of secondary prevention treatment in stroke.
- Trial name
- QUATRO (NCT05741593)
- Testing
- Analysis of the verbatim from the transcription of the recorded interviews.
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Chronic Stroke Patients
Effect of Transcutaneous Auricular Stimulation of the Vagus Nerve on Functional Connectivity in the Brain at Rest
The goal of this clinical trial is to study the effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on resting-state brain functional connectivity.
- Trial name
- COVAGNIRS (NCT07282106)
- Testing
- Active taVNS arm
- Where
- France
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Clinique Les Trois Soleils
Stroke, Dysphagia
Effect of Kinesio Taping Applied to the Suprahyoid Muscles on Swallowing Safety in Patients With Post-Stroke Dysphagia
Dysphagia is defined as a disorder that occurs during the process of food transfer, beginning with oral intake and continuing until it reaches the stomach.
- Conditions
- Stroke, Dysphagia, Swallowing Disorder
- Trial name
- Post-Stroke KT (NCT07255352)
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Harran University
Ischemic Stroke
Efficacy and Safety of SP-8203 in Patients With Ischemic Stroke Requiring rtPA
This clinical trial is designed to evaluate the efficacy and safety of the combination therapy of SP-8203 (Otaplimastat) and recombinant tissue Plasminogen Activator (rtPA) standard of care.
- Trial name
- SP-8203-2002 (NCT04479449)
- Testing
- SP-8203
- Where
- South Korea
- Volunteers
- 178 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis
Perception and Multisensory Integration in Neurological Patients Using fMRI
The main objective of the study is to explore and map brain areas involved in sensory perception and multisensory integration in patients with central or peripheral neurological damage.
- Conditions
- Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis, Stroke, Anosognosia
- Trial name
- NCT01469858
- Testing
- Siemens magnetom avanto1.5 Tesla, Siemens magnetom trio A Tim system 3 Tesla
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Chronic Stroke Survivors
GREEN Walk: A Nature-based Gait Training to Improve the Quality of Life Among Chronic Stroke Survivors
The purpose of the study is to find out if a nature-based gait training program titled GREEN Walk can help people with chronic stroke improve their physical, mental, and social health, as well as their overall quality of life.
- Trial name
- NCT07634315
- Testing
- GREEN Walk Training Program
- Where
- Philippines
- Volunteers
- 11 people
- Sponsor
- Mariano Marcos State University
Retinitis Pigmentosa, Maculopathy, Age Related
High Resolution, High-speed Multimodal Ophthalmic Imaging
Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging.
- Conditions
- Retinitis Pigmentosa, Maculopathy, Age Related, Macular Dystrophy, Macular Edema
- Trial name
- IMA-MODE (NCT04129021)
- Testing
- High-resolution retinal imaging through adaptive optics, High-resolution retinal imaging through holographic systems
- Where
- France
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Psychosocial, Narrative
Psychosocial Wellbeing Following Stroke
The purpose of this feasibility study is to develop and initially test a dialogue-based psychosocial intervention aimed at promoting coping and psychosocial wellbeing following an acute stroke.
- Conditions
- Psychosocial, Narrative, Coping, Quality of Life
- Trial name
- NCT01912014
- Testing
- Psychosocial support and counselling
- Where
- Norway
- Volunteers
- 25 people
- Sponsor
- University of Oslo
Heat Stroke
Study of Risk Factors for the Occurrence and Severity of Exertional Heatstroke in the Military Environment
Although the circumstances of onset and management of exertional heatstroke have been identified for several years, its pathophysiology remains imperfectly understood. Exertional heatstroke is the result of both extrinsic (i.e.
- Trial name
- EXPLO-CCE (NCT04593316)
- Testing
- Saliva collection, Questionnaires, Ingestible core temperature capsule intake
- Where
- 3 sites in France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Ischemic Stroke, Atherosclerosis
The Gut and Oral Bacteria, Atherosclerosis and Ischemic Stroke Study
The main aim of this project is to demonstrate an association between gut and oral microbiota and their metabolites to carotid atherosclerosis and risk of ischemic stroke.
- Conditions
- Ischemic Stroke, Atherosclerosis, Microbiota
- Trial name
- NCT04803838
- Testing
- No intervention
- Where
- Norway
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Mitral Valve Stenosis, Atrial Fibrillation
Efficacy and Safety of Edoxaban in Patients With Atrial Fibrillation and Mitral Stenosis
This study aims to compare the efficacy and safety of the edoxaban and the warfarin in atrial fibrillation patients with mitral stenosis.
- Conditions
- Mitral Valve Stenosis, Atrial Fibrillation, Stroke, Systemic Embolism
- Trial name
- ERTEMIS (NCT05540587)
- Testing
- Edoxaban, Warfarin
- Where
- 7 sites in South Korea
- Volunteers
- 240 people
- Sponsor
- Sung-Hwan Kim
Central Post Stroke Pain
Efficacy of Pain Intervention With Deep Brain Stimulation Neuromodulation
The goal of this clinical trial is to learn if deep brain stimulation (DBS) works to treat severe pain following a stroke in adults. It will also learn about the safety of deep brain stimulation.
- Trial name
- EPIONE (NCT06387914)
- Testing
- Stimulation ON, Stimulation Pseudo-ON
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Oxford
Stroke, Acute
Stroke and Rehabilitation in North of Norway and Central Denmark
Post-stroke prospective multicenter cohort study. The objectives of the study was to compare functioning and health related quality of life in the two study regions, in relation to known predictors and to differences in…
- Trial name
- NCT03948906
- Volunteers
- 815 people
- Sponsor
- University Hospital of North Norway
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