Clinical trials: Cerebral Vascular Accident
Stroke Patients and Their Caregivers
MPACT OF A HOME CARE GUIDE FOR DAILY LIVING ACTIVITIES ON STROKE CAREGIVERS' BURDEN AND EXPERIENCE
The study aims to develop a home care guide, led by nurses, for stroke patients to maintain their activities of daily living, based on evidence-based current literature and guidelines, and to test the effect of this guide on…
- Trial name
- NCT07640412
- Testing
- Training and Materials
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cumhuriyet University
Ischemic Stroke, Acute
Third Enhanced Control of Hypertension and Thrombectomy Stroke Domain Within ACT-GLOBAL Adaptive Platform Trial
Several clinical trials have produced variable conclusions regarding the effects of intensive blood pressure (BP) lowering in post-EVT acute ischaemic stroke (AIS) patients.
- Trial name
- ENCHANTED3/MT (NCT06352619)
- Testing
- Conservative SBP Control, Moderate SBP Control, Intensive SBP Control
- Where
- 2 sites in Australia, Canada
- Volunteers
- 2,000 people
- Sponsor
- The George Institute
Stroke, Acute Ischemic
Intravenous rhTNK-tPA Before Stroke Thrombectomy in the Extended Time Window
This randomized, double-blind, placebo-controlled phase III clinical trial aims to evaluate the efficacy and safety of intravenous recombinant human tenecteplase (rhTNK-tPA) in acute ischemic stroke patients with large vessel…
- Trial name
- NCT06987305
- Testing
- Intravenous rhTNK-tPA, Endovascular thrombectomy
- Where
- 4 sites in China
- Volunteers
- 820 people
- Sponsor
- Xinqiao Hospital of Chongqing
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Hemiplegia
Mirror Therapy Combined With TENS for Motor Recovery in Paretic Upper Limbs of Chronic Stroke Patients
The aim of this study is to determine whether mirror therapy, applied in addition to bilateral upper extremity transcutaneous electrical nerve stimulation in patients with chronic stroke, has an additive effect on upper extremity…
- Trial name
- NCT06770712
- Testing
- Mirror therapy, Transcutaneous Electrical Nerve Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Sinus Rhythm, Atrial Fibrillation
Prevention of Stroke and Sudden Cardiac Death by Recording of 1-Channel Electrocardiograms
Single-channel electrocardiograms (lead I of 12-lead surface ECG; 30 seconds) will be collected from subjects/patients at 11 clinical centers in Germany to train an Artificial Intelligence in the automatic diagnosis of regular…
- Conditions
- Sinus Rhythm, Atrial Fibrillation, Atrial Premature Complexes, Ventricular Premature Complexes
- Trial name
- PRICE (NCT04637230)
- Testing
- Electrocardiogram analysis by Artificial Intelligence
- Where
- Germany
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- A-Rhythmik GmbH
Ischemic Stroke, Hemorrhagic Stroke
Stroke and Traumatic Acute Brain Injury Line Indicator System for Emergent Recognition (STABILISER-I)
In the search for a novel marker of stroke that could be rapidly assessed in blood, the investigators developed a point-of-care (POC) lateral flow device (LFD) that rapidly (< 15 min) detects levels of a biomarker that is…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, Traumatic Brain Injury
- Trial name
- STABILISER-I (NCT02514902)
- Testing
- Lateral Flow Device
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Justin Fraser
Multiple Sclerosis, Epilepsy
Psychometric Evaluation in Patients With Brain Damage During Neuroinflammation
The presence of a damage to the central and / or peripheral nervous system resulting from diseases of a different nature (such as, Multiple Sclerosis, Parkinson's disease, dementia, head trauma, stroke, epilepsy or other…
- Conditions
- Multiple Sclerosis, Epilepsy, Parkinson Disease, Dementia
- Trial name
- NCT05450237
- Testing
- Psychometric Evaluations
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Neuromed IRCCS
Stroke, Stroke Rehabilitation
Video-based Sit-to-stand Evaluation for Stroke Patients
The purpose of this study is to develop and validate a novel video-based postural evaluation tool designed to objectively measure the quality and dynamics of the Sit-to-Stand (STS) motion in stroke patients, specifically allowing…
- Trial name
- NCT07359001
- Testing
- Observation
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Sahmyook University
Coronary Artery Disease, Myocardial Infarction
WENBIT - Western Norway B Vitamin Intervention Trial
PURPOSE OF STUDY Observational studies have demonstrated that elevated levels of plasma total homocysteine is a risk factor for cardiovascular disease.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Cerebrovascular Stroke
- Trial name
- WENBIT (NCT00354081)
- Testing
- folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine), folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine)
- Where
- 2 sites in Norway
- Volunteers
- 3,096 people
- Sponsor
- Haukeland University Hospital
Stroke
Mobile Terminal Based Management of Stroke Secondary Prevention Adminstration Effect Research
The investigators want to verify whether mobile application based on stroke strengthen prevention management is more effective than traditional management model or open stroke management platform.
- Trial name
- NCT02618265
- Testing
- Mobile terminal, traditional management, website platform management
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Peking University Third Hospital
Acute Ischemic Stroke
Hyperbaric Oxygen After Stroke Thrombectomy: A Multicenter Randomized Trial on Safety and Efficacy
1. The goal of this clinical trial is to evaluate the efficacy and safety of hyperbaric oxygen (HBO)in stroke patients after endovascular treatment 2.
- Trial name
- NOTICE-1 (NCT07049692)
- Testing
- Hyperbaric Oxygen Therapy, Conventional therapy group
- Where
- 2 sites in China
- Volunteers
- 424 people
- Sponsor
- Beijing Chao Yang Hospital
Stroke
Effects of Plantar Vibration on Gait and Balance in Stroke
This study aims to evaluate the effects of local vibration applied to the plantar surface of the foot on gait speed and dynamic balance in individuals with stroke.
- Trial name
- NCT07551141
- Testing
- Plantar Vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Bitlis Eren University
Brain Ischemia
Mild Hypothermia in Acute Ischemic Stroke
Hypothesis: Mild hypothermia using non-invasive temperature management system in a stroke unit is safe and feasible in spontaneously breathing, alteplase-thrombolyzed patients with acute ischemic stroke.
- Trial name
- NCT00987922
- Testing
- Hypothermia
- Volunteers
- 36 people
- Sponsor
- University of Helsinki
Ischemic Stroke
ThrombX Retriever for Acute Ischemic Stroke Trial
This trial is designed to assess the safety and effectiveness of the ThrombX Retriever.
- Trial name
- TRAC (NCT05270122)
- Testing
- Mechanical thrombectomy with ThrombX Retriever
- Volunteers
- 200 people
- Sponsor
- ThrombX Medical
Hemiplegia, Spastic
THE EFFECTS OF SUBTALAR JOINT MOBILIZATION ON PATIENTS WITH CHRONIC STROKE
Adequate ankle motion for normal gait ranges from 10° to 15° of dorsiflexion passive range of motion (DF-PROM) to allow the tibia to move over the talus.
- Trial name
- NCT03788629
- Testing
- Talocrural joint MWM mobilization, Subtalar joint MWM mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Ischemic Stroke
One Pass Tirofiban In Management of Ischemic Stroke Thrombectomy In China
In recent years, the positive results of trials for mechanical thrombectomy (MT) have brought a new era for large artery occlusion patients, especially those beyond the time window of intravenous thrombolysis.
- Trial name
- OPTIMISTIC (NCT04851457)
- Testing
- Intravenous tirofiban combination therapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai East Hospital
Stroke
Effects of Unilateral Step Training on Gait and Balance in Stroke Patients
According to the definition proposed by the World Health Organization, "stroke is rapidly developing clinical signs of focal (or global) disturbance of cerebral function, with symptoms lasting 24 hours or longer, or leading to…
- Trial name
- NCT05449301
- Testing
- Rhythmic Auditory Stimulation, Treadmill Training, Unilateral Step Training
- Where
- Pakistan
- Volunteers
- 63 people
- Sponsor
- Riphah International University
Stroke Volume Variation
Study of the Natural Variation in Strokevolume
We would like to investigate the natural variation in the strokevolume of the heart. At the same time we would like to find out the minimal number of heart cycles necessary to discover a 10% increase in strokevolume, after a…
- Trial name
- NCT00447200
- Testing
- Esophagus Doppler monitoring, Fluid optimization
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Intra Cerebral Hemorrhage, Stroke
Ultra-Early, Minimally inVAsive intraCerebral Haemorrhage evacUATion Versus Standard trEatment
A randomized controlled trial of ultra-early, minimally invasive, hematoma evacuation versus standard care within 8 hours of intracerebral hemorrhage.
- Trial name
- EVACUATE (NCT04434807)
- Testing
- Minimally invasive hematoma evacuation
- Where
- 13 sites in Australia
- Volunteers
- 240 people
- Sponsor
- University of Melbourne
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