Clinical trials: Cerebral Vascular Disorders
Aneurysmal Disease, Stroke
Prediction of Patient-specific Outcomes After Interventional neuroRadiology Procedures
Stroke is either an obstruction (ischemic stroke) or the rupture of a blood vessel in the brain (ruptured aneurysm). It can happen at any age in adults.
- Trial name
- PREDICTNRI (NCT04504695)
- Where
- France
- Volunteers
- 1,600 people
- Sponsor
- University Hospital, Brest
Vascular Dementia, Cognitive Impairment
Efficacy and Safety of Tian Ma Bian Chun Zhi Gan Tablets in Mild to Moderate Vascular Dementia
The study will be a 36-week multicentre, double-blind, placebo-controlled phase Ⅱb trial in China. Total 360 participants aged 55-80 years will be randomized to Tian Ma Bian Chun Zhi Gan group (84mg per day) or to placebo group.
- Trial name
- NCT05371639
- Testing
- Tian Ma Bian Chun Zhi Gan Tablets
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Dongzhimen Hospital, Beijing
Subarachnoid Hemorrhage, Cerebral Aneurysm
Amnesia After Surgery for Anterior Communicating Aneurysm： High Resolution Magnetic Resonance (MR) Imaging Findings
To clarify whether amnesia after treatment of anterior communicating aneurysm (ACoA)is related to infarcts caused by occlusion or damage of the perforating artery of the ACoA, we used 3.0-T 3D high resolution MR imaging to…
- Conditions
- Subarachnoid Hemorrhage, Cerebral Aneurysm, Amnesia
- Trial name
- NCT01919775
- Volunteers
- 14 people
- Sponsor
- Tohoku University
Stroke, Acute
HDL Dysfunction During the Acute Stage of Stroke
The study investigates the effect of plasma myeloperoxidase (MPO) concentrations on HDL dysfunction during the acute stage of ischemic and haemorrhagic strokes.
- Trial name
- RUSH (NCT03245957)
- Testing
- Ischemic stroke, Haemorrhagic stroke
- Where
- Reunion
- Volunteers
- 112 people
- Sponsor
- Centre Hospitalier Universitaire de la Réunion
HIV, Stroke
Impact of HIV-infection on Clinical Characteristics and Outcomes on Stroke in Uganda
The investigators will recruit participants from three tertiary care hospitals in Uganda into an observational cohort study of people living with HIV/AIDS (PLWHA) and HIV-uninfected persons matched for gender and residency…
- Trial name
- NCT03072212
- Testing
- Observational study
- Where
- Uganda
- Volunteers
- 200 people
- Sponsor
- Mbarara University of Science and Technology
Myocardial Infarction, Stroke (Including Ischaemic Stroke and Transient Ischaemic Attack)
Study to Gather Information to What Extent Patients Follow the Treatment Regimen of Low-dose Aspirin for Primary and Secondary Prevention of Diseases of the Heart and Blood Vessels
This study aims to gather information to what extent patients follow the treatment regimen of low-dose aspirin for primary and secondary prevention of diseases of the heart and blood vessels.
- Conditions
- Myocardial Infarction, Stroke (Including Ischaemic Stroke and Transient Ischaemic Attack), Unstable Angina, Angina
- Trial name
- PALACE (NCT04097912)
- Testing
- Acetylsalicylic Acid (Aspirin, BAYE4465)
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 99,999 people
- Sponsor
- Bayer
Intracranial Aneurysms
MAPS Trial: Matrix And Platinum Science
Primary Objectives: To establish Target Aneurysm Recurrence (TAR) rates for Matrix 2® and GDC® Coils used for the treatment of intracranial saccular aneurysms.
- Trial name
- MAPS (NCT00396981)
- Testing
- Matrix 2® coils for endovascular aneurysm occlusion, GDC® coils for endovascular aneurysm occlusion
- Where
- 43 sites in United States, Australia and 9 more
- Volunteers
- 626 people
- Sponsor
- Stryker Neurovascular
Stroke
Validation and Standardisation of a Pool of Simplified Evaluation Aimed to the Diagnoses of Aphasic Disorders and Adapted to the Patients Suffering an Acute Phase of Stroke
Every year in France, from 100 000 to 145 000 people are affected by a stroke. 75% patients survived with aftereffects, in particular aphasic disorders.
- Trial name
- BESTA-AVC (NCT02548481)
- Testing
- BESTA scale
- Where
- France
- Volunteers
- 395 people, healthy volunteers welcome
- Sponsor
- University Hospital, Limoges
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Perceptions of Burden in Patients With Late-Stage Cancer and Their Caregivers
RATIONALE: Gathering information over time about patients' sense of being a burden on their caregiver, and caregivers' sense of burden on themselves, may help doctors learn more about the desire to die in patients with late-stage…
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Depression, Leukemia
- Trial name
- NCT00770419
- Testing
- medical chart review, questionnaire administration, psychosocial assessment and care
- Sponsor
- Rutgers, The State University of New Jersey
Stroke, Gait, Hemiplegic
The Effect of Exercise by Mechanical Hippotherapy Device on Postural Stability and Balance in Stroke
Stroke,one of the leading cause of death, is caused by ischemia or hemorrhage. It results in neurological deficits such as hemiplegia. Hemiplegia show disability characterized loss of motor, sensory and cognitive function.
- Conditions
- Stroke, Gait, Hemiplegic, Balance, Postural
- Trial name
- NCT03528993
- Testing
- exercise by hippotherapy device, conventional rehabilitation, postural control exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medipol University Hospital
Stroke
Primed vs. Unprimed rTMS in Chronic Stroke
The goal of stroke rehabilitation is to restore function to the weak side of the body. However, this is often a difficult task to accomplish due to not only to damage from the stroke, but from increased excitability in the…
- Trial name
- NCT01757821
- Testing
- real 6-Hz primed low-frequency rTMS, real 1-Hz rTMS only
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Carotid Artery Diseases, Peripheral Arterial Disease
Study to Image Inflammatory Activity of a Fluorescence Imaging Agent in Excised Human Artery Plaques
Active inflammation plays a key role in causing Coronary Artery Disease (CAD) and Peripheral Arterial Disease (PAD). Since inflammation is so important in how these diseases start, are diagnosed, and treated, being able to see it…
- Trial name
- NCT06957821
- Testing
- Pegulicianine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Massachusetts General Hospital
Dementia, Cognitive Change
MIND Diet to Improve Cognitive Function in Mild Stroke Patients
A 6-month pilot randomized controlled trial designed to test the effect of the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet + usual medical care versus usual medical care on the rate of cognitive change…
- Conditions
- Dementia, Cognitive Change, Stroke, Cerebral Infarction
- Trial name
- MINDICOMS (NCT05921084)
- Testing
- MIND diet intervention, General dietary advice
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhejiang University
Stroke, Hemiplegia
Pelvic-Restricted vs. Pelvic-Free Robot-Assisted Gait Training in Stroke Patients
This randomized controlled clinical trial aims to compare the effects of pelvic-free versus pelvic-restricted robot-assisted gait training (RAGT) on gait pattern, balance, and fear of falling in stroke patients.
- Conditions
- Stroke, Hemiplegia, Gait Disorder, Sensorimotor, Balance Impairment
- Trial name
- NCT07365384
- Testing
- RoboGait® Pelvic-Free Mode, RoboGait® Pelvic-Restricted Mode, Conventional Rehabilitation
- Volunteers
- 36 people
- Sponsor
- Meltem Gunes Akinci
Acute Stroke
Efficacy of Whole Extract of Licorice in Neurological Improvement of Patients After Acute Ischemic Stroke
Stroke is one of the most important causes of mortality and disability both in developed and developing countries. The only food and drug administration (FDA) approved therapy for acute stroke is recombinant tissue plasminogen…
- Trial name
- NCT02473458
- Testing
- Licorice whole extract
- Where
- Iran
- Volunteers
- 75 people
- Sponsor
- Shiraz University of Medical Sciences
Stroke
Validity and Reliability of Sensorimotor Processing Paradigm
Sensorimotor function of the upper limb is often impaired after stroke, even in the chronic phase (minimum 6 months after stroke).
- Trial name
- NCT06382558
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- KU Leuven
Stroke, Ischemic, Upper Limb Injury
MOdularity for SEnsory Motor Control
For this project the investigators ask, how the activation and organization of muscle synergies may be disrupted by brain lesions, and whether it is possible to modify synergy activations by means of specific therapies.
- Conditions
- Stroke, Ischemic, Upper Limb Injury, Rehabilitation
- Trial name
- MOSE (NCT03530358)
- Testing
- Technology-aided rehabilitation, Conventional rehabilitation
- Where
- 2 sites in Italy
- Volunteers
- 132 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Atherosclerosis of Artery, Carotid Endarterectomy
Associations of Carotid Plaque Characteristics With Brain Perfusion and Cognitive Function in Patients Undergoing CEA
Stroke is one of the leading causes of death and disability-adjusted life-years worldwide. Carotid high-risk atherosclerotic plaques are considered to be one of the major sources of ischemic stroke.
- Trial name
- NCT04955015
- Testing
- carotid endarterectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Stroke, Stroke Patients
Combination of Force Control Training and Mirror Visual Feedback Device on Stroke Patients on Brain Activation and Hand Function
Global elderly population continues to grow. Among the diseases caused by aging, stroke accounts for the highest incidence, and the number of stroke patient is increasing year-by-year.
- Trial name
- NCT07150325
- Testing
- TIPr, Mirror Visual Feedback Device, Mirror Visual Feedback Device(Blocked mirror)
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Cheng-Kung University Hospital
Stroke
Blood Pressure Level and Prognosis in Acute Stroke
Stroke is the leading cause of mortality in Brazil. Strict blood pressure control in chronic phase is the major measure to primary and secondary prevention, but in acute phase is not clear the best blood pressure level.
- Trial name
- NCT01195350
- Where
- Brazil
- Volunteers
- 266 people
- Sponsor
- UPECLIN HC FM Botucatu Unesp