Clinical trials: Cerebral Vasospasm
Cerebral Vasospasm After Subarachnoid Hemorrhage
Safety Study of Dantrolene to Treat Cerebral Vasospasm After Subarachnoid Hemorrhage
Subarachnoid hemorrhage (SAH) is a devastating acute brain injury due to bleeding onto the brain surface from a ruptured aneurysm.
- Trial name
- NCT00964548
- Testing
- Dantrolene
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Massachusetts, Worcester
Cerebral Vasospasm
Cervical Spinal Cord Stimulation in Cerebral Vasospasm
The study is a non-blinded evaluation of the use of cervical spinal cord stimulation (SCS) for treatment of patients with Hunt and Hess grade 1-2 subarachnoid hemorrhage and evidence of cerebral vasospasm.
- Trial name
- SCSinCV (NCT02426827)
- Testing
- Spinal Cord Stimulation
- Sponsor
- Mayo Clinic
Subarachnoid Hemorrhage, Pneumonia, Bacterial
Influence of Pneumonia on Delayed Cerebral Ischemia After Subarachnoid Hemorrhage . SAH-CIP (SubArrachnoid Hemorrhage - Cerebral Infarction Pneumonia)
Prognosis of subarachnoid hemorrhage (SAH) is scarce, indeed almost half patients die or become severely disable after SAH. Outcome is related to the severity of the initial bleeding and delayed cerebral infarction (DCI).
- Trial name
- SAH-CIP (NCT05094349)
- Where
- France
- Volunteers
- 224 people
- Sponsor
- University Hospital, Brest
Subarachnoid Hemorrhage, Vasospasm, Intracranial
Prolonged Vasospasm in Subarachnoid Hemorrhage
The prevalence and clinical implications of prolonged cerebral vasospasm in patients with subarachnoid hemorrhage are unknown.
- Trial name
- PVE (NCT04193124)
- Testing
- transcranial doppler.
- Volunteers
- 109 people
- Sponsor
- Hospital El Cruce
Subarachnoid Hemorrhage
Stellate Ganglion Block as Adjuvant Therapy to ca Channel Blocker
Aim of work: To evaluate the effect of stellate ganglion block in prevention of cerebrovascular spasm in traumatic subarachnoid hemorrhage Primary outcome: Asses changes of cerebral blood flow velocity by Trans cranial Doppler.
- Trial name
- NCT04100824
- Testing
- stellate ganglion block by transcranial doppler, Nimodipine
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Traumatic Brain Injury
Physiologic Mechanisms in Pediatric Traumatic Brain Injury (TBI)
The aims of this study explore the relationships between cerebral vasospasm, apolipoprotein-E (apo-E) genotype, physiologic symptoms, and neurocognitive outcomes that may either intensify or ameliorate secondary injury, for…
- Trial name
- NCT01763892
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Vasospasm, Intracranial, Subarachnoid Hemorrhage
Lumbar Drain vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage
Vasospasm is a common complication after rupture of intracranial aneurysms causing devastating neurologic deficits and death. Vasospasm has been directly associated with the amount of subarachnoid blood inside the basal cisterns.
- Trial name
- NCT03065231
- Testing
- Extraventricular Drain, Lumbar Drain
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Diego
Brain Injury
Vasospasm in Pediatric Traumatic Brain Injury
The purpose of this study is to assess for vasospasm using Transcranial Doppler (TCD) and brain injury biomarkers, and evaluate neurocognitive outcome data in pediatric traumatic brain injury (TBI) patients who have experienced a…
- Trial name
- PTBI (NCT01461902)
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Duke University
Subarachnoid Hemorrhage, Delayed Cerebral Ischemia
CT Perfusion Imaging to Predict Vasospasm in Subarachnoid Hemorrhage
Patients with brain hemorrhage resulting from a ruptured aneurysm (SAH) are at risk of developing a condition called vasospasm, one or two weeks after their hemorrhage. This is a major cause of stroke and death following SAH.
- Conditions
- Subarachnoid Hemorrhage, Delayed Cerebral Ischemia, Cerebral Vasospasm, CT Perfusion
- Trial name
- CT-PIPS (NCT02056769)
- Testing
- CT Perfusion
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- Nova Scotia Health Authority