Clinical trials: Cerebrovascular Accident, Acute
Acute Ischemic Stroke
Hybernia Medical Post-Mechanical Thrombectomy Cerebral Cooling in Stroke
Reducing the temperature of tissue or organs (hypothermia) produces a protective state, through multiple molecular mechanisms, against adverse effects that arise from disrupted organ blood flow, e.g.
- Trial name
- Post-MECC (NCT06634303)
- Testing
- Brain cooling
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Hybernia Medical
Stroke, Acute, Cognitive Dysfunction
Validity and Reliability of a Self-evaluation Tool for Cognitive Deficits in the Acute Stage After Stroke
Cognitive disorders are common early after stroke but can be overseen in patients with mild stroke who seem to be functionally recovered but are at risk to experience difficulties in advanced daily activities affecting social…
- Trial name
- NCT04624529
- Testing
- Self evaluation tool
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- KU Leuven
Acute Stroke
Effect of Sour Liquid On Swallowing Function of the Patients With Stroke
The aim of this study was to evaluate the effect of early administration of sour liquid on swallowing function of patients with post-stroke dysphagia.
- Trial name
- NCT06013254
- Testing
- sour liquid
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Trakya University
Acute Ischemic Stroke
The Androtriol Injection for the Treatment of Acute Ischemic Stroke
This is a prospective, multicenter, randomized, double-blind, placebo-controlled, phase IIb clinical trial of Androtriol injection for the treatment of acute ischemic stroke.
- Trial name
- NCT06679322
- Testing
- Androtriol Injection (High-dose group), Androtriol Injection (Low-dose group), Hydroxypropyl-β-cyclodextrin injection
- Volunteers
- 300 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Acute, Stroke
Stroke Home Rehabilitation With WeReha
WeReha is an innovative device for the home rehabilitation of stroke patients developed within the scope of the EU funded project MAGIC-PCP [5].
- Trial name
- WR (NCT03964662)
- Testing
- WeReha
- Where
- 3 sites in Italy, United Kingdom
- Volunteers
- 150 people
- Sponsor
- CoRehab s.r.l.
Stroke, Thrombolysis
Efficacy and Safety of Intravenous Thrombolysis in Branch Atheromatous Disease
Rationale and Relevance: Branch Atheromatous Disease (BAD) describes an atherosclerotic occlusion of one of the deep penetrating cerebral arteries, including the lenticulostriate artery (LSA), paramedian pontine artery (PPA), and…
- Conditions
- Stroke, Thrombolysis, DAPT(Dual Antiplatelet Therapy), SAPT(Single Antiplatelet Therapy)
- Trial name
- NCT07299994
- Where
- 8 sites in Austria, Germany and 1 more
- Volunteers
- 462 people
- Sponsor
- Sigmund Freud PrivatUniversitat
Stroke, Ischemic
The Effect of The Five-Session Dual-tDCS On Lower-Limb Performance in Sub-Acute Stroke
The aim of the present study is to determine the effect of the five-session dual-tDCS combine with physical therapy on gait performance, balance and lower limbs muscle strength in patients with subacute stroke.
- Trial name
- NCT04287231
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Acute Ischemic Stroke, Acute Ischemic Stroke (AIS) Related to a Distal Occlusion
FORWARD: Functional Outcomes in Real-World Treatment And Revascularization of Non-dominant and Distal M2 Occlusions
The objective of this study is to collect safety and effectiveness data on the Penumbra System reperfusion catheters in participants with isolated primary non-dominant and distal M2 occlusions who undergo endovascular mechanical…
- Trial name
- NCT07749170
- Testing
- Endovascular Thrombectomy, Medical Management
- Where
- 7 sites in United States
- Volunteers
- 250 people
- Sponsor
- Penumbra Inc.
Stroke Acute, Acute Ischemic Stroke AIS
One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy
Stroke, especially acute ischemic stroke (AIS) caused by a blocked blood vessel in the brain, is a leading cause of death and long-term disability.
- Conditions
- Stroke Acute, Acute Ischemic Stroke AIS, Hemorrhagic Stroke, Intracerebral
- Trial name
- GET-FAST (NCT07052045)
- Testing
- One Stop Management, Usual care management
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 390 people
- Sponsor
- Prof. Dr. Jan Liman
Acute Ischemic Stroke
Brazilian Intervention to Increase Evidence Usage in Practice - Stroke (BRIDGE-Stroke)
Phase 1: An observational study ( registry) will be conducted with the objective of documenting the practice of stroke treatment in brazilian and latin american hospitals.
- Trial name
- BRIDGEStroke (NCT02223273)
- Testing
- Multifaceted Strategy
- Where
- Brazil
- Volunteers
- 1,624 people
- Sponsor
- Hospital do Coracao
Stroke, Acute
Use of Virtual Reality Game in Rehabilitation of Stroke Patients in Tan Tock Seng Hospital
Use of SIlverfit 3d to aid in rehab of stroke patients focusing on their shoulder and knee strength
- Trial name
- NCT04874181
- Testing
- Silverfit 3D
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Tan Tock Seng Hospital
Cognitive Impairment, Stroke
Hypoalbuminemia in Mild Acute Stroke and Cognitive Impariment Post-stroke
This registration enrolled patients with acute ischemic stroke within 72 hours after stroke ictus. Patients was identified as first-ever stroke based on past medical histrory.
- Conditions
- Cognitive Impairment, Stroke, Albumin; Double
- Trial name
- NCT04135872
- Testing
- strengthened nuitritional treatment
- Where
- China
- Volunteers
- 435 people
- Sponsor
- Dongguan People's Hospital
Ischemic Stroke, Haemorrhagic Stroke
The Effects of Posture on Cerebral Blood Flow Velocity During the Acute Phase of Stroke
After stroke, blood vessels in the brain can become damaged, and the brain's ability to control blood flow can be impaired. The brain therefore may be less able to maintain a healthy level of blood flow during challenges such as…
- Conditions
- Ischemic Stroke, Haemorrhagic Stroke, Cerebrovascular Accident, Acute Stroke
- Trial name
- NCT04972812
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- Sheffield Hallam University
Acute Ischemic Stroke
Study of BB-031 in Acute Ischemic Stroke Patients (RAISE)
The purpose of this study is to evaluate the safety and tolerability of ascending doses (Part A) and selected doses (Part B) of BB-031 in acute ischemic stroke patients presenting within 24 hours of stroke onset.
- Trial name
- RAISE (NCT06226805)
- Testing
- BB-031
- Where
- 25 sites in United States, Australia and 1 more
- Volunteers
- 228 people
- Sponsor
- Basking Biosciences, Inc.
Acute Decompensated Heart Failure
Change in Stroke Volume Index After Diuresis for Patients With Decompensated Heart Failure
This is a prospective cohort study for 50 patients admitted to the cardiac care unit requiring clinically-indicated diuretic therapy for congestive heart failure.
- Trial name
- NCT05240651
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NYU Langone Health
Cerebrovascular Accident (CVA), Stroke
Mirror Box Therapy for Upper Limb Function With Stroke
Individuals who have sustained a stroke are often left with residual deficits of the upper limb such as impaired movement and sensation.
- Trial name
- NCT02276729
- Testing
- Mirror Box Therapy
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Dr Alison Porter-Armstrong
Acute Ischemic Stroke, Large Vessel Occlusion
Tenecteplase Bridging Thrombolysis Prior to Inter-hospital Transfer for Endovascular Therapy in Anterior Circulation Large Vessel Occlusion Stroke Within 4.5-24 Hours
This multicenter, randomized clinical trial will assess whether intravenous tenecteplase given before interhospital transfer improves outcomes compared with direct transfer without tenecteplase.
- Trial name
- Union-transfer (NCT07912970)
- Testing
- Tenecteplase (rhTNK-tPA) (0.25 mg/kg, to maximum of 25mg)
- Where
- China
- Volunteers
- 1,266 people
- Sponsor
- Fujian Medical University Union Hospital
Acute Ischemic Stroke
Efficacy and Safety Evaluation of iNstroke 5F Aspiration Catheter for Thrombectomy
Prospective, single-arm, multi-centre study to evaluate the efficacy and safety of the iNstroke 5F thromboaspiration catheter in patients with acute ischaemic stroke
- Trial name
- iNFLOW-5 (NCT07571954)
- Testing
- Thromboaspiration catheter
- Where
- 7 sites in France, Spain
- Volunteers
- 45 people
- Sponsor
- iVascular S.L.U.
Aphasia
Effects of Transcranial Direct Current Stimulation in Post-stroke Aphasia
This study aims to determine whether transcranial direct current stimulation (tDCS) paired with speech-language therapy is more beneficial than speech-language therapy alone in acute and chronic post-stroke aphasia.
- Trial name
- NCT02622945
- Testing
- Active tDCS plus Speech-Language Therapy
- Where
- United States
- Sponsor
- Johns Hopkins University
Cardiac Arrest, Stroke
Prevalence of Acute Critical Neurological Disease in Children: a Global Epidemiological Assessment
PANGEA is an international prospective point prevalence study to describe the epidemiology, interventions, and outcomes in children with acute critical brain disease.
- Conditions
- Cardiac Arrest, Stroke, Traumatic Brain Injury, Brain Mass
- Trial name
- PANGEA (NCT02381977)
- Testing
- No intervention
- Volunteers
- 922 people
- Sponsor
- University of Pittsburgh
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