Clinical trials: Cerebrovascular Apoplexy
Cerebral Stroke
Facilitating Implicit Learning to Improve Neurorehabilitation in Stroke
Stroke is one of the leading causes of chronic disability in Veterans. Stroke is associated with significant loss of mobility, increased risk of falling, cardiovascular disease, depression and neuro-cognitive impairment.
- Trial name
- NCT02017574
- Testing
- Reaching Task
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Intracranial Aneurysm, Subarachnoid Hemorrhage
Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial
Aneurysmal subarachnoid hemorrhage (SAH) is a form of stroke in which secondary neurological deterioration is an important cause of mortality and morbidity.
- Trial name
- DASH (NCT02875262)
- Testing
- Deferoxamine
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Stroke, Stroke Sequelae
The StrokeCog Study: Cognitive Rehabilitation Intervention in Stroke
This study aims to progress to the next stage of feasibility testing, by conducting a pilot randomised controlled study with consecutive stroke patients who have mild to moderate cognitive impairment following stroke.
- Conditions
- Stroke, Stroke Sequelae, Cognitive Impairment
- Trial name
- StrokeCog-R (NCT06021470)
- Testing
- Cognitive rehabilitation intervention
- Volunteers
- 64 people
- Sponsor
- Royal College of Surgeons, Ireland
Stroke, Ischemic Stroke
Clinician JUdgment Versus Risk Score to Predict Stroke outComes: The JURASSIC Clinical Trial
Background: Several risk score models are now available to assist clinicians estimate outcomes after an acute ischemic stroke. Limited information is available on the predictive value of these scores compared to real outcomes and…
- Conditions
- Stroke, Ischemic Stroke, Cerebrovascular Disease
- Trial name
- JURASSIC (NCT01657279)
- Testing
- Clinical scenarios
- Where
- 4 sites in United States, Canada
- Volunteers
- 111 people
- Sponsor
- Unity Health Toronto
Acute Stroke
Which Factors Influence the Duration and the Success of Mechanical Thrombectomy During the Acute Phase of Cerebral Infarction?
This study aims to identify factors influencing the time span and success of reperfusion after a mechanical thrombectomy in the acute phase of cerebral infarction, and in particular the effect of intra-venous thrombolysis.
- Trial name
- REPAIR-FC (NCT03451903)
- Testing
- Actilyse, Mechanical thrombectomy
- Volunteers
- 106 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Atrial Fibrillation
The Role of Multimodality Imaging in Left Atrial Appendage Closure
The aim of the present prospective, randomized single-centre study is to examine the success rate, safety, overall preoperative and operative burden and long-time outcome of percutaneous left atrial appendage closure procedures…
- Trial name
- MILAAC (NCT04800913)
- Testing
- Multimodal imaging, Standard imaging
- Where
- Hungary
- Volunteers
- 44 people
- Sponsor
- Hungarian Institute of Cardiology
Stroke
Transcranial Direct Current Stimulation in Acute Ischemic Stroke Treatment
This prospective interventional single center randomized sham controlled dose-escalation study will assess safety, tolerability, feasibility and potential efficacy of transcranial direct current stimulation (tDCS) in acute stroke…
- Trial name
- DICAST-SF (NCT04801446)
- Testing
- Soterix Medical 1X1 tDCS stimulator (active C-tDCS)
- Where
- Czechia
- Volunteers
- 25 people
- Sponsor
- General University Hospital, Prague
Stroke, Rehabilitation
Patient Engagement Program for Stroke - Pilot Study
Currently there is a lot of literatures on stroke rehabilitation and post-discharge therapy. However, there are few evidence based guidelines on patient engagement after stroke in the post-rehabilitation community phase.
- Trial name
- PEPS (NCT01112488)
- Testing
- Patient Engagement Programme
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Kowloon Hospital, Hong Kong
Stroke
Foot Drop Rehabilitation and Mobility in Chronic Stroke
Stroke is a leading cause of long-term disability, frequently resulting in motor impairments, balance deficits, and walking difficulties that limit functional independence and quality of life.
- Trial name
- NCT07914413
- Testing
- Conventional Physical Therapy Program, FES-Assisted Gait Training
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Umm Al-Qura University
Stroke
Anti-platelet Precision Medicine to Prevent Stroke Early Progression and Recurrence (PRECISE)
This is a pragmatic, multi-center, non-interventional, non-randomized prospective observational study.
- Trial name
- NCT03701360
- Where
- South Korea
- Volunteers
- 1,199 people
- Sponsor
- Asan Medical Center
Stroke, Endovascular Thrombectomy
Multidimensional Evaluation of Patients With Acute Ischemic Stroke Undergoing Pharmacological and Endovascular Revascularization Procedures for the Identification of Positive Prognostic Factors
In developed countries, stroke is the third leading cause of death and the leading cause of permanent disability. Systemic and endovascular thrombolytic treatments in acute cerebral ischemic stroke caused by occlusion of large…
- Conditions
- Stroke, Endovascular Thrombectomy, Ischemic Stroke
- Trial name
- NCT05708079
- Testing
- Endovascular thrombectomy
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sarcopenic Obesity, Spinal Cord Injuries
Sarcopenic Obesity in Neurodisabilities
To describe the frequency and thresholds for sarcopenic obesity in neurodisabled persons and the fat and lean mass distribution based on various neurodisabilities
- Conditions
- Sarcopenic Obesity, Spinal Cord Injuries, Stroke, Multiple Sclerosis
- Trial name
- SarcObeNDS (NCT03863379)
- Testing
- whole body DXA
- Where
- Greece
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dionyssiotis, Yannis, M.D.
Stroke, Hemiplegia
Effects of Whole-body Vibration Exercise on Stroke Patients
The purpose of this study is to investigate the effect of the whole body vibration exercise on cortical activity and gait function in patients with chronic stroke.
- Trial name
- NCT03375346
- Testing
- Whole body vibration, Exercise
- Volunteers
- 29 people
- Sponsor
- Samsung Medical Center
Stroke
Use of BCAA-rich Protein Supplements for Chronic Stroke Patients
In the past few years, Branched Chain Amino Acid (BCAA) supplements have gradually used on different groups. From training athletes, maintaining functions of healthy elders to preventing disabilities of people that can't do…
- Trial name
- NCT03244527
- Testing
- BCAA supplement, Aerobic exercise
- Where
- 2 sites in Taiwan
- Volunteers
- 20 people
- Sponsor
- Taipei Medical University WanFang Hospital
Acute Stroke
A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients
This study was jointly developed and is jointly led by investigators at Massachusetts General Hospital and the intramural division of NINDS.
- Trial name
- MR WITNESS (NCT01282242)
- Testing
- IV rt-PA
- Where
- 14 sites in United States
- Volunteers
- 88 people
- Sponsor
- Lee Schwamm
Stroke Ischemic
Tenecteplase in ReperfUsion Therapy for Posterior Circulation Stroke With Extended Time Window: the TRUST Trial
The primary hypothesis being tested in this trial is that ischemic stroke patients in posterior circulation at 4.5 - 24 hours post onset of stroke will have improved clinical outcomes when given intravenous TNK compared to…
- Trial name
- NCT07073469
- Testing
- Tenecteplase (TNK) (0.25 mg/kg, to maximum of 25mg), Standard medical treatment
- Volunteers
- 330 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Ischemic Stroke, Stroke
Clinical Evaluation of EEG Device for the Triage of Stroke Patients in the Ambulance
Endovascular thrombectomy (EVT) is the standard treatment for large vessel occlusion (LVO) strokes, but it can only be performed in specialized hospitals.
- Conditions
- Ischemic Stroke, Stroke, Cardiovascular Diseases, Vascular Diseases
- Trial name
- CROSSROADS-EEG (NCT06871969)
- Testing
- Dry electrode EEG
- Where
- Netherlands
- Volunteers
- 275 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Stroke, Neglect, Hemispatial
Head Mount Display-based Virtual Reality Rehabilitation of Hemispatial Neglect
Head-mounted display based virtual reality rehabilitation for hemispatial neglect.
- Trial name
- NCT03463122
- Testing
- field of regard-focused visual exploration therapy, conventional therapy
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Atherosclerosis
Accelerated Atherosclerosis in High Risk Population Groups: An Assessment by Magnetic Resonance Imaging
The goal of this study is to assess a slimy substance that settles/deposits along blood vessel wall. This slimy substance is called plaque. Plaque could be made up of fat, calcium or both. Plaque deposition narrows the vessels.
- Trial name
- NCT02114697
- Testing
- Statin therapy, Lifestyle modification
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Emory University
Ischemic Stroke
Methanesulfonic Acid Cinepazide Injection for Treatment of Acute Cerebral Infarction
Using placebo as control, The purpose of this study is to evaluate the efficacy and safety of methanesulfonic acid cinepazide injection to relieve disabled degree of acute cerebral infarction patients, and explore the best safe…
- Trial name
- NCT01851759
- Testing
- cinepazide
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Xijing Hospital
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