Clinical trials: Cerebrovascular Disease; Sequelae, open to volunteers
Stroke, Stroke Sequelae
Novel Wrist Sensor System to Promote Hemiparetic Arm Use in Home Daily Life of Chronic Stroke Survivors
The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in chronic stroke survivors.
- Conditions
- Stroke, Stroke Sequelae, Hemiparesis;Poststroke/CVA
- Trial name
- NCT05626894
- Testing
- StrokeWear Motor and Behavioral Intervention, Usual Care
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke Patients, Stroke
Young Stroke Service Deep Phenotyping: Exploring Recovery in Young Adult Survivors of Stroke
The Investigators are running a small, early-phase research study across several hospitals in Melbourne, Australia. The study will involve up to 100 young adults between the ages of 18 and 55 who have had a stroke.
- Conditions
- Stroke Patients, Stroke, Stroke; Sequelae, Young Adults
- Trial name
- NCT07019493
- Testing
- Observational Cohort
- Where
- 2 sites in Australia
- Volunteers
- 100 people
- Sponsor
- The Florey Institute of Neuroscience and Mental Health
Stroke Sequelae
Efficacy and Safety of Deep Brain Stimulation in Mesencephalic Locomotor Region（MLR） for Poststroke Hemiplegia
Abstract: Background: The leftover movement disorder of stroke patients is one of the main causes of disability, and there is still no specific solution.
- Trial name
- NCT05968248
- Testing
- MLR-DBS, Conventional rehabilitation group
- Volunteers
- 62 people
- Sponsor
- Chinese PLA General Hospital
Stroke, Stroke Sequelae
A Novel Wrist Wearable Sensor System to Promote Hemiparetic Upper Extremity Use in Subacute Stroke Survivors
The proposed study is a two-arm randomized clinical trial designed to assess the effects of the StrokeWear system on clinical outcomes over a period of 6-months in subacute stroke survivors.
- Conditions
- Stroke, Stroke Sequelae, Hemiparesis;Poststroke/CVA
- Trial name
- NCT06797154
- Testing
- StrokeWear Behavioral Intervention
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Spaulding Rehabilitation Hospital
Spinal Cord Diseases, Spinal Cord Injuries
Optimization of Adaptive Rowing Seating
Adaptive sports programs are integral components to combating Veteran isolation, promoting wellbeing and seeking to build teams, networks, communities.
- Conditions
- Spinal Cord Diseases, Spinal Cord Injuries, Neurodegenerative Disorders, Cerebrovascular Accident With Associated Sequelae
- Trial name
- OARS (NCT07099625)
- Testing
- Adaptive Indoor Rowing Seat, Paddle Sport adaptive seating system
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Apathy, Stroke
Accelerated rTMS vs. Sham for Stroke Apathy
Apathy is a common set of symptoms seen in many people following a stroke. Apathy occurs when a person has lost motivation, becomes withdrawn, and stops doing things that used to be important to them.
- Conditions
- Apathy, Stroke, Stroke Sequelae, Stroke/Brain Attack
- Trial name
- NCT07113067
- Testing
- MagVenture MagPro Transcranial Magnetic Stimulation (TMS) System (Active), Brainsight Neuronavigation System
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical University of South Carolina
Stroke, Hemiplegia Following Ischemic Stroke
Improving STEP in Stroke Patients
Stroke is the leading cause of acquired disability in adults. Stroke causes death in 10% of patients, disability and functional handicap in 60% of cases.
- Conditions
- Stroke, Hemiplegia Following Ischemic Stroke, Disability Physical, Spasticity as Sequela of Stroke
- Trial name
- I-STEP (NCT07403149)
- Testing
- REMARCHE® shoes
- Volunteers
- 58 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stroke
Non-invasive Neuromodulation NESA Application in the Rehabilitation of Stroke Sequelae
To evaluate whether NESA microcurrents can be used as an effective treatment for various sequelae present in stroke patients, specifically in the treatment of spasticity, balance, pain; and whether it affects quality of life…
- Trial name
- NCT05853952
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- University of Las Palmas de Gran Canaria
Stroke Sequelae, Deep Brain Stimulation
Safety and Efficacy Study of Implantable Neuromodulation for Poststroke Hemiplegia
Background: Hemiplegia is a common complication after a stroke. Studies have shown that traditional medical and rehabilitation treatments are not good for improving patients' motor function, deep brain stimulation (DBS) and vagus…
- Conditions
- Stroke Sequelae, Deep Brain Stimulation, Vagus Nerve Stimulation, Motor Recovery
- Trial name
- NCT06121947
- Testing
- The DBS electrodes are implanted into MLR., The electrodes are implanted into the patient's vagus nerve
- Where
- China
- Volunteers
- 98 people
- Sponsor
- Chinese PLA General Hospital
Stroke, Stroke, Acute
Data Collection of Patients Admitted to the Stroke Unit
The purpose of this prospective observational study is to create a database in which data will be collected from every patient admitted to the Stroke unit and who has explicitly given his or her informed consent for this data…
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- PRODA-STROKE (NCT04956185)
- Where
- Belgium
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Ghent
Ictus, Stroke
Motor and Cognitive Telerehabilitation in a Virtual Environment in Patients With Post-stroke Sequelae and Parkinson's Disease
The goal of this interventional pilot trial is to evaluate whether a telerehabilitation protocol based on immersive virtual reality (VR) is effective and feasible for the recovery of cognitive and/or motor functions in patients…
- Conditions
- Ictus, Stroke, Parkinson Disease
- Trial name
- HOME VR REHAB (NCT07582497)
- Testing
- VR-based Telerehabilitation with Home Kit, Standard Rehabilitation (Conventional Care)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Azienda Usl di Bologna
Stroke, Stroke, Ischemic
Intracerebral Autologous Stem Cell Therapy for Chronic Stroke Patients
The goal of this clinical trial is to evaluate if autologous mesenchymal stem cell (HUNS001-01) transplantation therapy can provide neurological recovery in patients with chronic stage of stroke resulting in moderate to severe…
- Conditions
- Stroke, Stroke, Ischemic, Stroke; Sequelae
- Trial name
- RAINBOW-2a (NCT06752720)
- Testing
- Stem cell Transplantation
- Where
- Japan
- Volunteers
- 8 people
- Sponsor
- Hokkaido University Hospital
Stroke, Stroke Sequelae
Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition
This is a study using magnetoencephalography (MEG) to look at recovery in those with minor stroke. The investigators know that these individuals report difficulties in attention, concentration, multi-tasking, energy level, and…
- Conditions
- Stroke, Stroke Sequelae, Stroke/Brain Attack
- Trial name
- NCT04188522
- Testing
- Magnetoencephalography (MEG)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Johns Hopkins University
Stroke Sequelae, Gait Disorders, Neurologic
Efficacy of Trans-spinal Magnetic Stimulation on Functional Mobility in Chronic Stroke Patients
The goal of this clinical trial is to learn if trans-spinal magnetic stimulation works to treat gait disorders in chronic stroke adults. It will also learn about the safety of trans-spinal magnetic stimulation.
- Conditions
- Stroke Sequelae, Gait Disorders, Neurologic, Stroke
- Trial name
- NCT06593184
- Testing
- Trans-spinal magnetic stimulation
- Where
- 3 sites in Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal de Pernambuco
Stroke, Stroke Sequelae
TDCS to Improve Post-Stroke Cognitive Impairment
The investigators will conduct a randomized, double-blinded, sham-controlled trial of approximately 60 patients with minor stroke and post-stroke mild cognitive impairment (psMCI).
- Conditions
- Stroke, Stroke Sequelae, Cognitive Impairment
- Trial name
- TIPSCI (NCT05195398)
- Testing
- Anodal transcranial Direct Current Stimulation (A-tDCS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Johns Hopkins University
Motor Impairment, Motor Impairments
Transcutaneous Auricular Vagus Nerve Stimulation in Patients With Stroke
This study will evaluate the effects of transcutaneous vagus nerve stimulation in combination with physical rehabilitation on upper limb motor function of patients with stroke.
- Conditions
- Motor Impairment, Motor Impairments, Stroke, Stroke; Sequelae
- Trial name
- INPULSE (NCT06895005)
- Testing
- Transcutaneous auricular vagus nerve stimulation + rehabilitation therapy
- Where
- Colombia
- Volunteers
- 30 people
- Sponsor
- Fundación Cardiovascular de Colombia
Stroke, Acute, Stroke, Ischemic
Prognosis and Diagnosis of Spasticity in Acute-post Stroke Patients
Spasticity, or greater muscle resistance, is a major disabling condition following stroke. Recovery of lost motor function in patients with stroke may be affected by spasticity, which most commonly develops in elbow and ankle…
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic, Spasticity as Sequela of Stroke
- Trial name
- NCT05179473
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- McGill University
Stroke Sequelae, Stroke ( 3 Months After Onset)
Clinical Implementation of Multichannel Functional Electrical Stimulation Device for Gait Rehabilitation in Subchronic Stroke: A Feasibility Study
The goal of this interventional study is to evaluate the effect of multichannel functionnal electrical stimulation for subchronic stroke gait rehabilitation.
- Trial name
- NCT07211672
- Testing
- Multichannel functionnal electrical stimulation
- Volunteers
- 5 people
- Sponsor
- TOPMED
Dementia, Vascular, Stroke Sequelae
Home Tele Rehabilitation Therapy for Vascular Dementia
To determine whether the home telerehabilitation therapy is feasible and lessens caregiver burden in chronic stroke patients with and without vascular dementia (VaD)
- Trial name
- NCT06289569
- Testing
- Home telerehabilitation therapy
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- The Methodist Hospital Research Institute
Stroke, Weakness of Extremities as Sequela of Stroke
Effects of Exoskeleton-Assisted Gait Training on Functional Rehabilitation Outcomes in Patients With Stroke
The goal of this study is to determine the efficacy of electromechanical exoskeleton-assisted gait training on rehabilitation functional outcomes in patients with stroke undergoing therapy in an in-patient rehabilitation facility.
- Trial name
- NCT03980457
- Testing
- Indego Exoskeleton, Standard Rehabilitation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Oklahoma