Clinical trials: Cerebrovascular Disease
Stroke, Stroke (CVA) or TIA
The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)
Stroke is a major cause of death and disability worldwide, frequently resulting in persistent cognitive deficits among survivors.
- Conditions
- Stroke, Stroke (CVA) or TIA, Dementia, Vascular, Cerebrovascular Disorders
- Trial name
- IC3 (NCT05885295)
- Testing
- MRI brain, Blood tests, cognitive assessments
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Hemiparesis as Late Effect of Cerebrovascular Disease
Role of Functional Translation After Immersive Virtual Reality Exposure in Persons With Stroke
This is a single-blinded randomized control trial aiming to explore the use of immersive virtual reality (VR) training in conjunction with real-life tasks therapy in 75 first time stroke patients with upper limb weakness.
- Trial name
- NCT04360460
- Testing
- Immersive virtual reality + related functional translation into real-life, Immersive virtual reality + non-related translation into real-life
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Loma Linda University
Ischemic Stroke, Stroke in the Young
Observational Dutch Young Symptomatic StrokE studY - nEXT
BACKGROUND: Worldwide, 2 million patients aged 18-50 years suffer an ischemic stroke each year with an increasing trend over the past decade due to yet unknown reasons.
- Conditions
- Ischemic Stroke, Stroke in the Young, Cardiovascular Diseases, Cerebrovascular Disorders
- Trial name
- ODYSSEY-nEXT (NCT05853796)
- Where
- 6 sites in Netherlands
- Volunteers
- 280 people
- Sponsor
- Radboud University Medical Center
Intracerebral Hemorrhage, Cerebral Hemorrhage
ENRICH: Early MiNimally-invasive Removal of IntraCerebral Hemorrhage (ICH)
This is a multicenter, randomized, adaptive clinical trial comparing standard medical management to early (<24 hours) surgical hematoma evacuation using minimally invasive parafascicular surgery (MIPS) in the treatment of acute…
- Conditions
- Intracerebral Hemorrhage, Cerebral Hemorrhage, Intracerebral Haemorrhage
- Trial name
- ENRICH (NCT02880878)
- Testing
- Early Surgical Hematoma Evacuation
- Where
- 36 sites in United States
- Volunteers
- 300 people
- Sponsor
- Nico Corporation
Brain Diseases, Cardiovascular Diseases
pRESET for Occlusive Stroke Treatment
Compare the safety and effectiveness of pRESET to Solitaire in the treatment of stroke related to large vessel occlusion
- Conditions
- Brain Diseases, Cardiovascular Diseases, Central Nervous System Diseases, Cerebrovascular Disorders
- Trial name
- PROST (NCT03994822)
- Testing
- Mechanical Thrombectomy using the pRESET Thrombectomy device, Mechanical Thrombectomy using the Solitaire Revascularization Device
- Where
- 24 sites in United States, Germany
- Volunteers
- 340 people
- Sponsor
- phenox Inc.
Cardiovascular Diseases, Cerebrovascular Disorders
Dietary Patterns and Health Outcomes (Cardiovascular, Metabolic, Endocrine, Neurological, Skeletal Muscular, Cancer)
To study, prospectively, the association between dietary patterns and risk of health outcomes (cardiovascular, metabolic, endocrine, neurological, skeletal muscular, cancer) in cohort study of 116,671 women age 24 to 44 years at…
- Conditions
- Cardiovascular Diseases, Cerebrovascular Disorders, Metabolic Disease, Neoplasms
- Trial name
- NCT03328546
- Testing
- Dietary intake
- Volunteers
- 116,671 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Cardiovascular and Cerebrovascular Diseases
Correlation Between Coronary Artery and Brain Study
To explore the pathogenesis of cardiovascular and cerebrovascular diseases through study on cardio-cerebral integration based on multimodal imaging technology, and clinical evaluation of its secondary diseases and intervention…
- Trial name
- NCT05813405
- Testing
- Experimental: Antihypertensive therapy Hypotension and improved ventilation treatment Intervention treatment for other risk factors
- Volunteers
- 1,000 people
- Sponsor
- Chinese PLA General Hospital
Ischemic Attack, Transient, Transient Ischemic Attack
Pocket Sized Carotid Stenosis Screening by Junior Doctors
Among patients admitted with cerebral ischemia (stroke and transitory ischemic attack (TIA)) it is important to reveal the underlying cause of the disease.
- Conditions
- Ischemic Attack, Transient, Transient Ischemic Attack, Stroke, Cerebrovascular Accident
- Trial name
- NCT02992821
- Testing
- Bed-side pocket size ultrasound imaging, High frame rate tracking doppler
- Where
- 2 sites in Norway
- Volunteers
- 75 people
- Sponsor
- Helse Nord-Trøndelag HF
Cerebral Amyloid Angiopathy, Small Vessel Cerebrovascular Disease
Prognosis of Cerebral Small Vessel Disease
Prognosis of small vessel disease (SVD) depends on the underlying type of SVD and index manifestation. The aim of this prospective, observational cohort study is to determine the risk of different outcome events among patients…
- Conditions
- Cerebral Amyloid Angiopathy, Small Vessel Cerebrovascular Disease, Cadasil, CAA - Cerebral Amyloid Angiopathy
- Trial name
- PRO-SVD (NCT05734378)
- Where
- Switzerland
- Volunteers
- 900 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cerebral Small Vessel Diseases, Inflammation
INflammation and Small Vessel Disease Study
A prospective observational cohort study in patients with cerebral small vessel disease deterring whether changes in systemic inflammation predict brain white matter damage measured using MRI and cognitive decline.
- Conditions
- Cerebral Small Vessel Diseases, Inflammation, Stroke
- Trial name
- INSVD (NCT05746221)
- Where
- 2 sites in Netherlands, United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Cambridge
Cerebrovascular Diseases, Ischemic Stroke
Genetic, Metabolic, and Growth Factor Repository for Cerebrovascular Disorders
This study encompasses the maintenance and utilization of a repository of samples from patients with cerebrovascular disease and stroke.
- Conditions
- Cerebrovascular Diseases, Ischemic Stroke, Repository
- Trial name
- NCT02910180
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Cedars-Sinai Medical Center
Radiology, Cerebral Stroke
Deep Enhanced Imaging in Stroke and Vascular Neurology
To investigate the performance of enhanced computed tomography (CT) or magnetic resonance (MR) imaging by deep learning relative to conventional CT or MR imaging in brain stroke and vascular neurology.
- Conditions
- Radiology, Cerebral Stroke, Vascular Diseases
- Trial name
- NCT05614193
- Testing
- Deep learning imaging enhancement
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Chinese PLA General Hospital
Cerebral Infarction, Stroke
In the Real World Study, the Efficacy and Adverse Reactions of Ticagrelor on Ischemic Cerebrovascular Disease
This is a forward-looking, open, one-arm, and real clinical trial world. The researchers plan to recruit at least 50 qualified patients.
- Conditions
- Cerebral Infarction, Stroke, Nervous System Diseases, Ischemic Cerebrovascular Disease
- Trial name
- NCT05716646
- Volunteers
- 50 people
- Sponsor
- Qianfoshan Hospital
Stroke, Cerebral Infarction
Arm Boot Camp Study: Evaluation of a Program to Increase Upper Limb Recovery After Stroke
This study will examine the feasibility and effect of a program that combines exercise and feedback from a wearable device on upper limb movement practice and function in individuals with stroke.
- Conditions
- Stroke, Cerebral Infarction, Brain Diseases, Central Nervous System Diseases
- Trial name
- NCT04232163
- Testing
- Arm Boot Camp
- Where
- 7 sites in Canada
- Volunteers
- 62 people
- Sponsor
- University of British Columbia
Small Vessel Cerebrovascular Disease, Stroke
Intensive Blood Pressure Control in Ischaemic Stroke Patients With Severe Cerebral Small Vessel Disease
Objectives: Cerebral small vessel disease (SVD) is a common disease in patients with ischemic stroke and the most common cause of vascular dementia. Blood pressure (BP)-lowering is generally considered neuroprotective.
- Trial name
- NCT05690997
- Testing
- Intensive treatment, Standard treatment
- Where
- Hong Kong
- Volunteers
- 104 people
- Sponsor
- The University of Hong Kong
Young Adult, Hypertension in Pregnancy
Cardiovascular Longitudinal ALSPAC Research Investigations Following Hypertensive Pregnancy in Young Adulthood
The purpose of this study is to understand more about why young people who were born to a hypertensive pregnancy may have increased risk of high blood pressure and are often at increased risk of heart and blood vessel disease…
- Conditions
- Young Adult, Hypertension in Pregnancy, Hypertension, Cardiovascular Diseases
- Trial name
- CLARITY (NCT05683093)
- Testing
- History of being born to hypertensive or normal pregnancy
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Oxford
Carotid Artery Disease, Atherosclerosis
Telerobotic Ultrasound for Carotid Imaging - Feasibility Study
In this proposal, the investigators will demonstrate the feasibility and noninferiority of telerobotic ultrasonography as compared to traditional manual acquisition in performing a limited carotid Duplex examination and in…
- Conditions
- Carotid Artery Disease, Atherosclerosis, Atheromatous Plaques, Arteriosclerosis
- Trial name
- NCT05654935
- Testing
- Ultrasound for Carotid Arteries, Telerobotic Ultrasound for Carotid Arteries
- Volunteers
- healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Intracranial Vascular Disease
DANTE SPACE for Evaluation of Subjects With Intracranial Vascular Disease
Purpose: The purpose of this study is to evaluate the Delay Alternating with Nutation for Tailored Excitation (DANTE) SPACE sequence in clinical studies to determine whether it can provide more useful information for clinical…
- Trial name
- NCT05505071
- Testing
- DANTE SPACE sequence
- Sponsor
- University of North Carolina, Chapel Hill
Stroke, Stroke, Ischemic
Telerehabilitation With Aims to Improve Lower Extremity Recovery Post-Stroke
The purpose of this study is to examine the feasibility and effectiveness of a lower extremity telerehabilitation protocol with aims to improve lower extremity recovery among community-living stroke survivors across Canada.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic, Cerebral Infarction
- Trial name
- TRAIL (NCT04265664)
- Testing
- Telerehabilitation
- Where
- 5 sites in Canada
- Volunteers
- 32 people
- Sponsor
- University of British Columbia
Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease, Heroin Addicts
Effect of Exercise on Cognitive Function and Mental Health in Heroin Addicts
The goal of this [type of study: exercise intervention study] is to test in describe participant health conditions. The main questions it aims to answer are: [Whether physical exercise improves executive function of male heroin…
- Conditions
- Unspecified Symptoms and Signs Involving Cognitive Functions Following Unspecified Cerebrovascular Disease, Heroin Addicts, Executive Function, Negative Thinking/Affect
- Trial name
- NCT05650983
- Testing
- Aerobic exercise; Resistance exercise
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Guangzhou Sport University