Clinical trials: Cerebrovascular Disease
Stroke, Gait, Unsteady
A Novel Ballet-inspired Low-impact At-home Workout Programme for Adults with Stroke
To explore the feasibility of a novel ballet-inspired low-impact at-home workout programme for community-dwelling stroke survivors in Hong Kong.
- Conditions
- Stroke, Gait, Unsteady, Balance; Distorted, Memory Impairment
- Trial name
- NCT04460794
- Testing
- Ballet-inspired workouts, Usual care
- Where
- Hong Kong
- Volunteers
- 32 people
- Sponsor
- Chinese University of Hong Kong
Ischemic Stroke
Registry Study of Stenting for Symptomatic Intracranial Artery Stenosis in China
The SAMMPRIS suggested that aggressive treatment was superior to intravascular stenting in patients with severe symptomatic intracranial atherosclerotic stenosis (ICAS) due to high complication rate in patients in stenting group.
- Trial name
- NCT01968122
- Testing
- intravascular stent therapy
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongrong Miao
First Ever Clinical Stroke, Ischemic Stroke
Rehabilitation Combined With Bihemispherictranscranial Direct Current Stimulation in Subacute Ischemic Stroke
Rehabilitation after stroke improves motor functions by promoting plastic changes however, after completing standard rehabilitation, 50-60% of patients still exhibit some degree of motor impairment and require at least partial…
- Conditions
- First Ever Clinical Stroke, Ischemic Stroke, Subacute Phase, Persistent Hemiparesis of Upper Extremity
- Trial name
- RECOMBINE (NCT01644929)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- 3 sites in Switzerland
- Volunteers
- 36 people
- Sponsor
- Dr. med. Carlo Cereda
Cerebrovascular Accident
Robot-assisted Gait Training for Patients With Stroke
Investigation of the clinical feasibility and efficacy of a newly developed robot-assisted gait training system for stroke survivors.
- Trial name
- NCT02781831
- Testing
- Standard rehab, Robot-assisted gait rehabilitation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- China Medical University Hospital
Ischemic Stroke
Focal Cortical Atrophy After Myocardial Internal Capsule
Primary purpose of the trial is to demonstrate the arisen of focal cortical atrophy, localized in the ipsilateral primary motor area, measured in mm, three months after infarction of internal capsule.
- Trial name
- ACFI (NCT01862172)
- Testing
- Additional MRI
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Toulouse
Hypertension
Blood Pressure Follow-up Study in Two Chinese Cohorts(C-BPCS)
Essential hypertension is a complex trait which results from interaction between environmental factors and genetic factors. The aim of this study is to investigate the effects of interaction between environmental factors and…
- Trial name
- C-BPCS (NCT02734472)
- Testing
- Incidence and risk factors of hypertension
- Where
- China
- Volunteers
- 5,298 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Stroke
Electrical Stimulation and a Dynamic Orthosis for Stroke Recovery
Objective: To explore the effectiveness of a combined neuromuscular electrical stimulation (ES) and dynamic hand orthosis (DHO) regimen used with a small group of persons with chronic stroke in improving ability to perform daily…
- Trial name
- NCT02887872
- Testing
- Electrical stimulation-dynamic hand orthosis
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Carotid Artery Stenosis, Ischemic Stroke
Platelet Reactivity and MES During CEA
The purpose of this study is to analyze the association between aspirin efficacy and general platelet reactivity in relation to microembolic signals (MES) during carotid endarterectomy (CEA).
- Conditions
- Carotid Artery Stenosis, Ischemic Stroke, Myocardial Infarction, Aspirin Resistance
- Trial name
- NCT01547039
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- UMC Utrecht
Stroke
Non-invasive VNS in Stroke Recovery
To evaluate feasibility and effectiveness of non-invasive VNS to enhance stroke recovery
- Trial name
- NOVUS (NCT06761404)
- Testing
- taVNS
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- The Methodist Hospital Research Institute
Carotid Atherosclerosis, Carotid Intimal Medial Thickness 1
Effects of Lutein Supplementation on Subclinical Atherosclerosis
This study is to investigate the possible positive effects of lutein and lycopene supplementation on early atherosclerosis in Beijing.
- Trial name
- NCT01534533
- Testing
- Lutein group, Combination group, Normal lutein control group
- Where
- China
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Peking University
Brain Ischemia, Hemiplegic Patients With Stroke
Using fMRI and sEMG to Evaluate the Effects and Mechanism on Abdominal Acupuncture Combined With Upper Limb Rehabilitation Training on Brain Plasticity of Hemiplegic Patients With Stroke
Using random number method to categorize the selected first onset patients with stroke who meet the inclusion criteria into 3 groups.The patients were randomly divided into treatment group A(abdominal acupuncture+upper limb…
- Conditions
- Brain Ischemia, Hemiplegic Patients With Stroke, Image Science, Electrophysiology of Neuromuscular
- Trial name
- NCT03712085
- Testing
- Abdominal acupuncture
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 66 people
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Middle Cerebral Artery Aneurysm
Risk Factors of Middle Cerebral Artery Aneurysm.
According to the current view, cerebral aneurysms are acquired degenerative lesions resulting from hemodynamic stress. This single-center case-control study will be carried out at the Department of Neurosurgery, Regional Hospital…
- Trial name
- MCAA (NCT03493035)
- Testing
- Computed tomography angiography (3D CTA), Transcranial color-coded sonography (TCCS)
- Where
- Poland
- Volunteers
- 190 people
- Sponsor
- Medical University of Silesia
Atrial Fibrillation, Stroke, Ischemic
Use of Oral Anticoagulants and Symptoms in Patients With Atrial Fibrillation in Örebro County
Atrial fibrillation (AF) is the most common sustained arrhythmia and the number of patients with AF is expected to increase substantially in the coming decades.
- Trial name
- NCT04233515
- Testing
- Oral anticoagulant
- Where
- Sweden
- Volunteers
- 11,964 people
- Sponsor
- Region Örebro County
Stroke
Upper Limb tDCS in Chronic Stroke Patients (NOURISH)
This study is a randomized double-blinded trial investigating the effect of Transcranial Direct Current stimulation (tDCS) on upper limb motor function rehabilitation in chronic stroke patients.
- Trial name
- NCT05608525
- Testing
- transcranial current stimulation, GRASP
- Where
- Singapore
- Volunteers
- 11 people
- Sponsor
- National University Hospital, Singapore
Ischemic Stroke
Robot-Assisted Gait Therapy in the Subacute Phase of First Ischemic Stroke
Robot-assisted gait training (RAGT) represents a modern concept of neurorehabilitation in stroke patients. This single-center randomized parallel-group neurorehabilitation trial with blinded primary outcome assessment is aimed at…
- Trial name
- NCT04910217
- Testing
- Conventional rehabilitation, Leg/lower body exerciser device intervention., Lokomat intervention
- Where
- Czechia
- Volunteers
- 80 people
- Sponsor
- University Hospital Ostrava
Aneurysmal Subarachnoid Hemorrhage (aSAH)
Correcting Hypocapnia in Aneurysmal Subarachnoid Hemorrhage.
Based on the clinical observation that over half of the patients in the management of aneurysmal subarachnoid hemorrhage(aSAH) present with spontaneous hyperventilation, which is significantly associated with delayed cerebral…
- Trial name
- NCT07343232
- Testing
- Normobaric Facemask Oxygen, control group
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The Chinese University of Hong Kong, Shenzhen
Intracerebral Haemorrhage
NICardipine for Fast Achievement of Systolic BP Targets in ICH
Quality improvement study with a quasi-randomized design. The study monitors the effect of a gradually implemented treatment algorithm prioritizing intravenous antihypertensives (e.g., nicardipine) over long-acting nitrate…
- Trial name
- NICFAST (NCT07044232)
- Testing
- Nicardipine, Glyceryl trinitrate
- Where
- Denmark
- Volunteers
- 88 people
- Sponsor
- Aarhus University Hospital
Subarachnoid Hemorrhage, Severe Traumatic Brain Injury
Outcomes Associated With Application of a Normothermia Protocol in Patients With Severe Neurological Insult and Fever
When fever is present in patients with stroke, traumatic brain injury (TBI), or brain hemorrhage, it has been associated with worse outcomes including larger areas of tissue death, increased length of stay, worse degree of coma…
- Trial name
- SNIF (NCT00890604)
- Testing
- Stepwise normothermia protocol, Ibuprofen, Acetominophen
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
Brain Hypoxia Ischemia
Continuous, Non-invasive Monitoring of Intraoperative Cerebral Perfusion and Oxidative Metabolism (CPOM)
This study uses a CPOM Optical neuromonitor to assess the relationship between brain cytochrome C oxidase, cerebral oxygen saturation and blood pressure during surgery performed under general anesthesia.
- Trial name
- NCT03907904
- Testing
- CPOM Optical Neuromonitor
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Western University, Canada
Hematoma, Subdural, Chronic
Preventing Recurrences of Chronic Subdural Hematoma in Adult Patients by Middle Meningeal Artery Embolization
Patients with a chronic subdural hematoma (cSDH), that is, a blood accumulation between two meninges developing over a long period of time, often have recurrent bleedings after an initial operation.
- Trial name
- MEMBRANE (NCT05327933)
- Testing
- Surgery plus endovascular MMA embolization, Surgery alone
- Where
- Germany
- Volunteers
- 154 people
- Sponsor
- Unfallkrankenhaus Berlin
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