Clinical trials: Cerebrovascular Disease
Stroke
Correlating Brain Tissue Oxygen and Regional Cerebral Oximetry
Controversy surrounds the use of regional cerebral oximetry (rSO2) as a measure of true cerebral oxygenation because of extracranial signal contamination and unmeasured confounding of cerebral a:v ratio.
- Trial name
- NCT03128957
- Testing
- IVOS cerebral oximeter, Licox cerebral oxygenation monitor, Cerebral oxygenation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Myocardial Infarction, Stroke, Ischemic
Study of Circulating Monocytes in Patients With Ischemic Vascular Disease
The purpose of this research study is to discover the functions of circulating white blood cells, called monocytes, and associated circulating substances in heart attack and ischemic stroke patients.
- Conditions
- Myocardial Infarction, Stroke, Ischemic, Ischemia
- Trial name
- NCT04321512
- Testing
- There is no intervention given to the subjects
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- UConn Health
Cerebrovascular Accident
Strength Training Effectiveness Post-Stroke (STEPS)
The purpose of this study is to determine if treadmill training with body weight-support (BWST) is more effective at improving walking in individuals post-stroke than a resisted leg-cycling exercise program.
- Trial name
- NCT00389012
- Testing
- exercise therapy, walking rehabilitation
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Southern California
Stroke
Effects Of Transcutaneous Vagus Nerve Stimulation With Virtual Reality In Post-Stroke Patients
Stroke is a neurological condition also known as cerebrovascular accident occurs when blood supply to the brain is disrupted ,either by blockage or rupture of a blood vessels.
- Trial name
- NCT06632665
- Testing
- transcutaneous vagus nerve stimulation+virtual reality+routine physical therapy, transcutaneous vagus nerve stimulation+routine physical therapy
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Cerebrovascular Disease
Aerobic Dance Training in Small Vessel Disease
Introduction: Cerebral small vessel disease (SVD) is associated with age-related disabilities including dementia, depression, physical and functional impairment. Chinese are more prone to developing SVD than Caucasians.
- Trial name
- ADTSVD (NCT02730065)
- Testing
- Structured Aerobic Dance Training Group, Stretching plus education
- Where
- 2 sites in Hong Kong
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke
Autologous Endothelial Progenitor Cells Transplantation for Chronic Ischemic Stroke
Stroke is a frequently occurring and common diseases in nervous system,and most of the survivors will remain disorders of motor,sensory and cognition function.Stem cell transplantation provides a promising approach for…
- Trial name
- NCT02605707
- Testing
- Intravenous stem cell transplantation
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Southern Medical University, China
Stroke, Ischemic
The Effect of The Five-Session Dual-tDCS On Lower-Limb Performance in Sub-Acute Stroke
The aim of the present study is to determine the effect of the five-session dual-tDCS combine with physical therapy on gait performance, balance and lower limbs muscle strength in patients with subacute stroke.
- Trial name
- NCT04287231
- Testing
- Transcranial direct current stimulation
- Where
- Thailand
- Volunteers
- 24 people
- Sponsor
- Mahidol University
Stroke
A Very Early Standing Study in Elderly Stroke
Functional recovery is one of the main issues in the management of stroke and there are various ways in rehabilitation to promote this recovery.
- Trial name
- AVESSES (NCT03424031)
- Testing
- Verticalization
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Stroke
Impact of Mirror Therapy Combined With Conventional Training on Gait and Lower Limb Motor Function Among Post-Stroke Patients
This randomized controlled trial aims to evaluate the effects of mirror therapy combined with conventional training on gait and lower limb motor function among post-stroke patients.
- Trial name
- NCT07797712
- Testing
- Mirror Therapy Based Functional Training, Conventional Lower Limb Training
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ibadat International University, Islamabad
Stroke
Technology-assisted Rehabilitation After Acute Stroke
The aim of the study is to evaluate the effects and costs of an intensified rehabilitation for stroke patients. Using novel technologies the patients will receive an augmented exercise therapy during the first weeks after stroke.
- Trial name
- NCT04647812
- Testing
- Technology-assisted rehabilitation, Conventional rehabilitation
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Vetrea Terveys Oy
Stroke,
A Clinical Trial to Study the Safety and Efficacy of Bone Marrow Derived Autologous Cell for the Treatment of Stroke.
This study is single, centre trial to study the safety and efficacy of Bone marrow derived autologous MNCS(100 million per dose)trial to be conducted for 36 months in stroke patients , the primary outcome measure will be the…
- Trial name
- BMACS (NCT01832428)
- Testing
- Intra thecal transplantation of Autologous Stem Cells
- Where
- India
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chaitanya Hospital, Pune
Stroke
The Feasibility, Usability, and Acceptability of Using the Oculus™ Virtual Reality Gaming Technology in Stroke Survivors for Upper Extremity and Cognitive Rehabilitation
The purpose of this study is to test the (a) feasibility, (b) usability, and (c) acceptability of using the Oculus Virtual Reality (VR) for chronic stroke survivors who have mild-moderate cognitive and unilateral arm impairment…
- Trial name
- NCT05672628
- Testing
- Oculus VR
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- The University of Texas Health Science Center, Houston
Cerebrovascular Accident (CVA), Chronic Disease
Upper Limb Task-Oriented Rehabilitation With Robotic Exoskeleton for Hemiparetic Stroke Patients
The aim of this study is to evaluate the effects of an assisted rehabilitation treatment through a robotic exoskeleton device on the functional recovery in a group of patients with hemiparesis from lesion of the first motor…
- Conditions
- Cerebrovascular Accident (CVA), Chronic Disease, Stroke Rehabilitation
- Trial name
- RH-LEXOS (NCT03319992)
- Testing
- Upper Arm Rehabilitation Light Exoskeleton (RH-LEXOS)
- Where
- Italy
- Volunteers
- 26 people
- Sponsor
- Scuola Superiore di Studi Universitari e di Perfezionamento Sant'Anna
Cerebral Small Vessel Disease, Stroke
Cerebral Small Vessel Disease Progression Dependent on Stroke Type
The goal of this prospective, observational study is to understand if cerebral small vessel disease (CSVD) has different velocities and patterns of temporal development, dependent on a concurrent ischemic stroke.
- Conditions
- Cerebral Small Vessel Disease, Stroke, Stroke Recurrence, Biomarkers
- Trial name
- ZMA_BIO (NCT07611136)
- Where
- Germany
- Volunteers
- 180 people
- Sponsor
- Johannes Dorst
Stroke
Stroke Cincinnati Prehospital Stroke Severity Scale Evaluation iN prEhospital
The effectiveness of acute ischemic stroke (AIS) management has improved considerably in recent years with thrombolysis and more recently with mechanical thrombectomy (MT).
- Trial name
- SCENE (NCT03181412)
- Testing
- Questionnaire
- Where
- 12 sites in France
- Volunteers
- 1,272 people
- Sponsor
- Hospices Civils de Lyon
HIV, Stroke
Impact of HIV-infection on Clinical Characteristics and Outcomes on Stroke in Uganda
The investigators will recruit participants from three tertiary care hospitals in Uganda into an observational cohort study of people living with HIV/AIDS (PLWHA) and HIV-uninfected persons matched for gender and residency…
- Trial name
- NCT03072212
- Testing
- Observational study
- Where
- Uganda
- Volunteers
- 200 people
- Sponsor
- Mbarara University of Science and Technology
Ischemic Stroke, Carotid Artery Disease
Norwegian Carotid Plaque Study
BACKGROUND: In 30-40% the cause of ischemic stroke remains undetermined. Most likely, this category hides an additional number of strokes caused by artery-to-artery embolisms due to unidentified atherosclerotic disease, or caused…
- Conditions
- Ischemic Stroke, Carotid Artery Disease, Embolic Stroke
- Trial name
- NOR-PLAQ (NCT02759653)
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- Haukeland University Hospital
Carotid Artery Stenosis
Neuroimaging Correlates of Memory Decline Following Carotid Interventions
Carotid revascularization can significantly reduce the risk of stroke in patients with severe carotid stenosis; however, it has been associated with cognitive decline in 25% of the older adults who undergo the procedure.
- Trial name
- NCT02006095
- Testing
- Magnetic resonance imaging, Neuropsychological testing
- Where
- United States
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Stanford University
Stroke, Acute, Thrombolytic Therapy
Thrombolysis Outcome in Ischemic Stroke
Consecutive patients with diagnosis of acute ischemic stroke and candidate of thrombolytic therapy during Jan 2017-Mar 2019 in BuAli Sina Hospital ,Sari, Iran, enrolled to this cohort study.
- Conditions
- Stroke, Acute, Thrombolytic Therapy, Alteplase, Mortality
- Trial name
- TOSSI (NCT04309357)
- Testing
- Alteplase
- Where
- Iran
- Volunteers
- 214 people
- Sponsor
- Mazandaran University of Medical Sciences
Acute Ischemic Stroke
Efficacy and Safety of Mildronate for Acute Ischemic Stroke
This study seeks to evaluate the efficacy and safety of mildronate injection in treating acute ischemic stroke
- Trial name
- NCT01800357
- Testing
- infusion of mildronate, aspirin
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Xijing Hospital
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