Clinical trials: Cerebrovascular Disease
Stroke, Parkinson Disease
Wearable Airbag Technology to Mitigate Falls in Individuals With High Fall Risk
The purpose of this study is to evaluate the feasibility and efficacy of a smart airbag system that detects and mitigates fall-related impact in individuals with high fall risk.
- Conditions
- Stroke, Parkinson Disease, Lower Limb Amputation Knee, Fall Injury
- Trial name
- NCT05076565
- Testing
- Airbag Belt Fall Protection System
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Shirley Ryan AbilityLab
Cerebrovascular Accident
A Post Discharge Intervention to Improve Stroke Outcomes
The purpose of this randomized controlled trial (RCT) is to test the effectiveness of a comprehensive interdisciplinary post-discharge stroke care management intervention in improving the overall well-being of 190 stroke…
- Trial name
- NCT00328471
- Testing
- care management
- Volunteers
- 380 people
- Sponsor
- Summa Health System
Stroke
Robotic Telerehabilitation of the Upper Limb in Stroke
The goal of the study is to investigate the feasibility and the effects of a home-based upper-limb rehabilitation treatment (based on teleconsulting, telemonitoring, and robotic telerehabilitation using the robot Icone and…
- Trial name
- TELEREHAB (NCT05250934)
- Testing
- Robotic rehabilitation
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
MELAS Syndrome, Mitochondrial Respiratory Chain Deficiencies
Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers
The purpose of this First In Human study is to investigate the safety and tolerability of KL1333 after a single oral dose and to investigate the pharmacokinetic characteristics of KL1333 after a single oral dose.
- Trial name
- NCT03056209
- Testing
- KL1333 25 mg, KL1333 50 mg, KL1333 100 mg
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Yungjin Pharm. Co., Ltd.
Stroke, Multiple Sclerosis
Improving Social Cognition and Social Behaviour in Various Brain Disorders
Impairments in aspects of social cognition are disorder-transcending: these have been demonstrated in various neurological disorders, such as traumatic brain injury (TBI), stroke, brain tumours (both low grade glioma's and…
- Conditions
- Stroke, Multiple Sclerosis, Brain Tumor
- Trial name
- T-ScEmo4ALL (NCT06330298)
- Testing
- Treatment social cognition and emotion regulation (T-ScEmo)
- Where
- 2 sites in Netherlands
- Volunteers
- 84 people
- Sponsor
- University Medical Center Groningen
Stroke, Acute
Treating Sleep Apnea Induced Hypoxemia With Oxygen in Acute Stroke Patients
We want to determine if treating acute ischemic stroke patients who have evidence of hypoxemia due to sleep apnea with low flow O2 during sleep might help improve clinical and functional outcomes.
- Trial name
- NCT03300063
- Testing
- Low flow nocturnal oxygen
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Stroke, Ischemic Stroke
Dietary Intervention With the Modified Atkins Diet in Stroke Rehabilitation
This phase 1 study tests whether use of the Modified Atkins Diet (MAD) can improve motor impairment after stroke. It is based on the hypothesis that after stroke, the brain's utilization of glucose, it's primary source of energy…
- Trial name
- NCT01820663
- Testing
- Modified Atkins Diet, Control diet
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Burke Rehabilitation Hospital
Stroke
Self-Managed Exercise in Chronic Stroke
This pilot study will assess the feasibility of a novel intervention to promote long-term self-managed exercise for post-stroke community-dwelling individuals.
- Trial name
- NCT07799987
- Testing
- Exercise, Behavioral Management Program
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Florida
Peripheral Artery Disease (PAD), Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))
Hemodynamic Parameters in People With Atherosclerotic Vascular Disease Referred to a Secondary Prevention and Cardiovascular Rehabilitation Program
The main purpose of this study is to evaluate the hemodynamic changes in the forefoot of patients with coronary, cerebrovascular or peripheral atherosclerotic disease referred a 12-week cardiovascular rehabilitation program (PREV…
- Conditions
- Peripheral Artery Disease (PAD), Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD)), Cerebrovascular Atherosclerosis
- Trial name
- NCT06701032
- Testing
- Cardiovascular rehabilitation program
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Laval University
Subdural Hematoma
Evaluation of One Burr Hole Evacuation for Subdural Hematoma
To evaluate the outcome of one burrhole evacuation for subdural hematoma and it has the same result of traditional two burrhole
- Trial name
- NCT06119932
- Testing
- Evacuation for subdural hematoma by one burrhole
- Where
- 2 sites in Egypt
- Volunteers
- 35 people
- Sponsor
- Assiut University
Stroke
The Effects of Extracorporeal Shock Wave Therapy on Upper Extremity Spasticity and Function in Patients With Stroke
Spasticity is a common complication after stroke and can limit upper extremity motor control and activities of daily living. Radial extracorporeal shock wave therapy (rESWT) is a non-invasive treatment that has been investigated…
- Trial name
- NCT07532187
- Testing
- Radial Extracorporeal Shock Wave Therapy (rESWT)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Hereditary Hemorrhagic Telangiectasia
Cerebral Hemorrhage Risk in Hereditary Hemorrhagic Telangiectasia
This study is one of the three projects of an NIH Rare Disease Clinical Research Consortium. A "consortium" is a group of centres sharing information and resources to perform research.
- Trial name
- BVMC6203 (NCT01158807)
- Where
- 19 sites in United States, Canada and 1 more
- Volunteers
- 2,272 people
- Sponsor
- Unity Health Toronto
Aneurysmal Subarachnoid Hemorrhage
Early Hydrogen-Oxygen Gas Mixture Inhalation in Patients With Aneurysmal Subarachnoid Hemorrhage (HOMA)
This was a randomized, single-center trial. On the basis of standard-of-care, patients in the treatment group inhaled H2-O2 (66% hydrogen; 33% oxygen) at 3 L/min via nasal cannula by using the Hydrogen/Oxygen Generator (model…
- Trial name
- HOMA (NCT05282836)
- Testing
- Hydrogen Oxygen Generator with Nebulizer
- Volunteers
- 206 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Osteoporosis
Assessment and Comparison of Osteoporosis Risk Factors After Stroke
The aim of this study is to evaluate the effects of stroke and associated clinical, functional, nutritional, and muscular factors, including handgrip strength, on bone mineral density and osteoporosis by comparing patients with…
- Trial name
- NCT07228611
- Testing
- Bone Mineral Density
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Stroke
Revascularization Pretreated With Fingolimod in Acute Stroke
Acute ischemic stroke (AIS) is a common type of stroke in the elderly. Timely blood flow recovery can effectively improve the long-term prognosis of patients.
- Trial name
- REPAIR FAST (NCT04718064)
- Testing
- Fingolimod
- Volunteers
- 20 people
- Sponsor
- The Affiliated Hospital of Xuzhou Medical University
Stroke
Non-invasive Auricular Vagus Nerve Stimulation (taVNS) on Postural Control and Autonomic Responses in Stroke
This randomized controlled trial is conducted to determine the effects of transcutaneous auricular Vagus nerve stimulation (taVNS) on postural control in stroke patients (e.g., improvements in balance, mobility, and functional…
- Trial name
- NCT07629687
- Testing
- Vagus Nerve Stimulation combined with Balance Training Group, Balance Training Group
- Where
- Pakistan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Ischemic Stroke, Digital Health
Prevention of Ischemic Stroke Recurrence Using Digital Technology Application
The goal of this study is to find out whether a comprehensive management program that uses a smart bracelet and a mobile app can help people who have had an ischemic stroke (a type of stroke caused by a blocked blood vessel in…
- Trial name
- DESIRE (NCT07825311)
- Testing
- Digital Prevention Management, Usual Stroke Secondary Prevention Management
- Where
- China
- Volunteers
- 1,696 people
- Sponsor
- Affiliated Hospital of Nantong University
Fabry Disease
Open Label Extension of 2 mg/kg Pegunigalsidase Alfa (PRX-102) Every 4 Weeks in Adult Fabry Disease Patients
The objective of CLI-06657AA1-03 (formerly PB-102-F51) is to evaluate the long-term safety, tolerability, and efficacy of 2 mg/kg pegunigalsidase alfa administered intravenously every four weeks in adult Fabry patients who have…
- Trial name
- NCT03614234
- Testing
- pegunigalsidase alfa
- Where
- 14 sites in United States, Belgium and 5 more
- Volunteers
- 29 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Intracranial Aneurysms
Post-Market Product Surveillance of Intracranial ANeurysms Treated With Commercial ReGistered ACANDIS Devices in FrancE
The aims of this clinical data collection are to investigate mortality, morbidity and neurological outcome 12 months after treatment of subject's intracranial aneurysm(s) and additionally to evaluate potential residual risks…
- Trial name
- ANCRAGE PMS (NCT06940934)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Acandis GmbH
Stroke
Effect of Intensive Cognitive Rehabilitation on Cognitive, Motor, and Language Functional Networks in Subacute Stroke Patient
Altered brain networks, including cognitive, motor, and language networks, are investigated by intensive cognitive rehabilitation in subacute stroke patients.
- Trial name
- NCT05254964
- Testing
- Cognitive rehabilitation
- Where
- South Korea
- Sponsor
- Samsung Medical Center
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