Clinical trials: Cerebrovascular Disease
Chronic SDH and the Efficacy of Embolization
Endovascular Embolization for Chronic Subdural Hematomas Following Surgical Evacuation
This study is designed to evaluate the effectiveness of endovascular embolization of middle meningeal artery following evacuation of subdural hematomas (SDHs) to assess rate of recurrence.
- Trial name
- endovascular (NCT04272996)
- Testing
- Craniotomy only, Craniotomy + Endovascular embolization of the middle meningeal vessels
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Augusta University
Horton Disease
Velocimetric Study of Temporal Arteries in Patients With Horton Disease Using Scan-Doppler
The use of ultrasonography in detecting giant cell arteritis ( GCA) is emerging. Currently, temporal biopsy is the gold standard to diagnose GCA but studies have shown the interest to use B mode ultrasonography.
- Trial name
- VELHOR (NCT03360162)
- Where
- France
- Volunteers
- 46 people
- Sponsor
- University Hospital, Brest
Stroke, Cognitive Symptoms
Cerebral Lesions and Outcome After Cardiac Surgery (CLOCS)
Between 1 and 5 percent of patients who have coronary artery bypass surgery suffer a stroke following surgery, and 30 percent have new brain lesions that do not produce symptoms and are seen only on MRI.
- Trial name
- NCT00391378
- Where
- United States
- Volunteers
- 363 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Effects of Robotic Rehabilitation in Post-Stroke Patients
This study aims to evaluate the effect of robotic rehabilitation through training on a robot-assisted orthostatic board and neuromuscular electrical stimulation (NMES) on functionality in post-stroke patients.
- Trial name
- NCT04494685
- Testing
- Intervention group (Robotic rehabilitation), Control group (Conventional physiotherapy)
- Volunteers
- 40 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Stroke
Merging Yoga and Group OT (MY-OT) to Improve Balance and Decrease Fall Risk After Stroke
The long-term goal of this project is to advance best practices in occupational therapy (OT) to manage fall risk factors and reduce fall rates in older adults with stroke.
- Trial name
- MY-OT (NCT02933515)
- Testing
- yoga and occupational therapy
- Volunteers
- 14 people
- Sponsor
- Colorado State University
Stroke, Acute, Ischemic Stroke
Melatonin in Acute Stroke
This study will measure Interleukin 6 (IL-6), a well-documented inflammatory biomarker that is increased in the acute phase of stroke, and to compare its levels after the administration of melatonin - a well-documented…
- Trial name
- NCT03843008
- Testing
- Melatonin
- Where
- United States
- Sponsor
- University of Florida
Stroke
GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy
We aim to determine if targeted high-definition transcranial direct current stimulation (HD-tDCS) can safely correct errors in visual verticality perception in patients after stroke affecting either hemisphere.
- Trial name
- GravNegElect (NCT06747676)
- Testing
- Active: High-Definition transcranial Direct Current Stimulation (HD-tDCS)
- Where
- 2 sites in Brazil
- Volunteers
- 28 people
- Sponsor
- University of Sao Paulo
Stroke
Evaluation of Improvement in Mobility Skills for Sub-acute Stroke Patients, Using the Selfit System.
Stroke is a leading cause of mobility disability for adults. Selfit is an advanced practice system that enables a wide range of exercises to improve patient mobility in the sub-acute stage after a stroke.
- Trial name
- Selfit (NCT03671876)
- Testing
- Intervention plus therapy
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Selfit Medical
Stroke
SURA'A Campaign for Stroke Awareness in Primary Health Care Centers
This study aims to evaluate the effectiveness of a one-week multifaceted Stroke Urgency Recognition, and Action Awareness (SURA'A) consultation-based campaign in increasing stroke awareness and the intention to seek emergency…
- Trial name
- SURA'A (NCT07578259)
- Testing
- SURA'A Consultation-Based Campaign
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Ischemic Stroke, Alteplase Adverse Reaction
the Predictors of Hemorrhagic Transformation Subtypes in Acute Embolic Stroke Patients
The investigators evaluated the impact of AF on different subtypes of post-alteplase hemorrhagic transformation of brain infarction.
- Trial name
- NCT06653946
- Testing
- Alteplase
- Where
- Egypt
- Volunteers
- 716 people
- Sponsor
- Kafrelsheikh University
Subarachnoid Hemorrhage
Prehospital Deaths From Spontaneous Subarachnoid Haemorrhages
In this study we aim to determine the incidence of fatal spontaneous subarachnoid haemorrhage outside hospital. Also, we aim to investigate these patient´s pattern of contact to the health care system immediately before their…
- Trial name
- NCT04052646
- Testing
- Medical condition: Subarachnoid hemorrhage
- Where
- Denmark
- Volunteers
- 58 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis
Perception and Multisensory Integration in Neurological Patients Using fMRI
The main objective of the study is to explore and map brain areas involved in sensory perception and multisensory integration in patients with central or peripheral neurological damage.
- Conditions
- Acute Inflammatory Demyelinating Polyradiculoneuropathy, Myasthenia Gravis, Stroke, Anosognosia
- Trial name
- NCT01469858
- Testing
- Siemens magnetom avanto1.5 Tesla, Siemens magnetom trio A Tim system 3 Tesla
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Acute Ischemic Stroke, Thrombolysis
Application of Standardized Green Channel Treatment System for Ischemic Stroke in Xi 'an
Objective: To observe the practical application of the standardized green channel treatment system for stroke in Xi 'an in the real world.
- Conditions
- Acute Ischemic Stroke, Thrombolysis, Endovascular Treatment
- Trial name
- Asgctsis (NCT05424978)
- Testing
- Standardized green channel treatment methods for stroke
- Where
- China
- Volunteers
- 3,600 people
- Sponsor
- Xi'an No.3 Hospital
Stroke
The Stroke Box: a Patient-centered eHealth Approach for Improving Post-stroke Care.
Although there have been major advances in (personalized) stroke treatment in the last decade, the need for prevention of stroke remains critical.
- Trial name
- NCT05388578
- Testing
- Blood pressure monitor, Weighting scale, Activity tracker
- Where
- Netherlands
- Volunteers
- 55 people
- Sponsor
- Leiden University Medical Center
Stroke
Peripheral Nerve Stimulation and Motor Training in Stroke
Cerebrovascular disease is a major cause of disability worldwide. The catastrophic burden of stroke is more dramatic in low- and middle- income countries, and the scarcity of evidence-based rehabilitation interventions represents…
- Trial name
- NCT02658578
- Testing
- PNS
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Carotid Artery Diseases, Stroke
The Role of Maintaining External Carotid Artery Flow in Graft Interposition After Carotid Endarterectomy
Analyzing results of carotid graft interposition with and without flow preservation through external carotid artery after endarterectomy.
- Conditions
- Carotid Artery Diseases, Stroke, Carotid Atherosclerosis
- Trial name
- AGICS (NCT06528717)
- Testing
- Carotid graft interposition
- Where
- Serbia
- Volunteers
- 250 people
- Sponsor
- Institute for Cardiovascular Diseases Dedinje
Hypoxia-Ischemia, Brain
Development of a High-speed Multimodal Photoacoustic/Ultrasound System for Functional Imaging of the Neonatal Brain
In today's medical field, there is a growing emphasis on the development of functional and molecular imaging. Therefore, it has significant technical limitations.
- Trial name
- NCT06139250
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cerebral Aneurysm
DELTA Trial: Does Embolization With Larger Coils Lead to Better Treatment of Aneurysms Trial
Endovascular treatment with platinum coils is safe and effective in preventing rebleeding of intracranial aneurysms. Unfortunately, endovascular treatment of aneurysms with coils has been associated with incomplete occlusion at…
- Trial name
- DELTA (NCT01943591)
- Testing
- Endovascular coiling with standard 10-caliber platinum coils or 15-caliber platinum coils
- Where
- 15 sites in United States, Canada
- Volunteers
- 210 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Stroke
tDCS and Motor Training and Motor Deficit After Stroke
This study investigated the combined effects of anodal tDCS and intensive motor training (MT) vs. sham stimulation with MT (control intervention) on grip strength, motor performance and functional use of the affected arm in…
- Trial name
- NCT02542982
- Testing
- tDCS (Endomed 482; Enraf-Nonius B.V.)
- Where
- Serbia
- Volunteers
- 26 people
- Sponsor
- Military Medical Academy, Belgrade, Serbia
Alzheimer Dementia, Dementia, Vascular
Tailored Music Therapy for Dementia
This study evaluates the effect and process of individualized music therapy for home-dwelling persons with mild to moderate dementia. The music therapy is administered individually and includes a close caregiver.
- Conditions
- Alzheimer Dementia, Dementia, Vascular, Dementia, Lewy Body, Dementia Parkinson's Disease
- Trial name
- NCT03011723
- Testing
- Resource oriented music therapy
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- University of Bergen
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