Clinical trials: Cerebrovascular Disease
Stroke (CVA) or Transient Ischemic Attack
Improve Medication Adherence Among Stroke Survivors in Rural Kentucky
To test the feasibility and promise of a combined intervention provided by community health worker (CHW) in collaboration with pharmacy technician and pharmacist to improve hypertension and long-term stroke outcomes by…
- Trial name
- I-MAS (NCT07084051)
- Testing
- I-MAS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Hend Mansoor
Stroke
Effectiveness of FACoT for Individuals Post Stroke
To develop and assess the effectiveness of a novel cognitive-functional intervention (FACoT) in occupational therapy for people after mild to moderate stroke.
- Trial name
- NCT02925637
- Testing
- FaCoT
- Where
- Israel
- Volunteers
- 66 people
- Sponsor
- Bait Balev Hospital
Stroke, Sarcopenia
Evaluating and Monitoring Physical Fatigue While Performing Functional Activities
Fatigue is a critical health parameter in older adults and stroke patients and is associated with negative health outcomes. Current assessment tools predominantly focus on walking related fatigue, neglecting other activities of…
- Conditions
- Stroke, Sarcopenia, Fatigue
- Trial name
- NCT06513377
- Testing
- Performance test
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Fabry Disease
This Study is Designed to Evaluate PD/PK and Safety of Replagal Manufactured by Two Different Processes.
This study is designed to evaluate safety and PK/PD in Canadian Fabry patients.
- Trial name
- NCT01304277
- Testing
- agalsidase alfa
- Where
- 5 sites in Canada
- Volunteers
- 17 people
- Sponsor
- Shire
Stroke
Technology-assisted Rehabilitation After Acute Stroke
The aim of the study is to evaluate the effects and costs of an intensified rehabilitation for stroke patients. Using novel technologies the patients will receive an augmented exercise therapy during the first weeks after stroke.
- Trial name
- NCT04647812
- Testing
- Technology-assisted rehabilitation, Conventional rehabilitation
- Where
- Finland
- Volunteers
- 40 people
- Sponsor
- Vetrea Terveys Oy
Stroke
The Effect of Resistance to Participant-Supported Reaching on Workspace of the Hand in Severe Chronic Stroke
Disturbances in movement coordination are the least well understood but often the most debilitating with respect to functional recovery following stroke.
- Trial name
- NCT01548781
- Testing
- Impairment-based robotic intervention for reaching function
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Northwestern University
Stroke, Acute
Protective Effects of Normobaric Hyperoxia on Blood Brain Barrier in Patients With Acute Ischemic Stroke
The purpose of this study is to find out a serum marker for the evaluation of blood brain barrier damage based on animal experiments and investigate the effect of NBO（Normobaric hyperoxia）on blood brain barrier in the acute…
- Trial name
- NCT02974283
- Testing
- Normobaric oxygen therapy
- Volunteers
- 40 people
- Sponsor
- Capital Medical University
Infant, Premature, Anemia
Liberal Versus Restrictive Transfusion Guidelines for Preterm Infants
The purpose of this study was to determine whether restrictive guidelines for red blood cell (RBC) transfusions for preterm infants can reduce the number of transfusions without adverse consequences.
- Conditions
- Infant, Premature, Anemia, Intracranial Hemorrhages, Leukomalacia, Periventricular
- Trial name
- NCT00369005
- Testing
- Red blood cell transfusion guidelines
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Basilar Artery Occlusion, Acute Cerebrovascular Accident
Intravenous Tenecteplase Plus EVT Versus EVT Alone on 4.5 to 24 Hours After Basilar Artery Occlusion
To assess the effect of intravenous tenecteplase plus endovascular thrombectomy (EVT) compared to EVT alone on 4.5 to 24 hours after stroke due to basilar artery occlusion.
- Conditions
- Basilar Artery Occlusion, Acute Cerebrovascular Accident, Stroke Due to Basilar Artery Occlusion
- Trial name
- NCT05701956
- Testing
- Tenecteplase, Endovascular thrombectomy
- Where
- China
- Volunteers
- 330 people
- Sponsor
- The First Affiliated Hospital of University of Science and Technology of China
Subarachnoid Hemorrhage, Aneurysmal, Cerebral Vasospasm After Subarachnoid Hemorrhage
Endovascular Therapy for Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage
Cerebral vasospasm is a common and serious complication after aneurysmal subarachnoid hemorrhage and is an important cause of delayed cerebral ischemia and poor neurological outcomes.
- Trial name
- RESCUE-CV (NCT07643922)
- Testing
- Intra-arterial and Intravenous Milrinone Therapy, Standardized Medical Management
- Where
- 2 sites in China
- Volunteers
- 306 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Stroke, Acute, Ischemic Stroke
TeleStroke-Guided Thrombolysis for Acute Ischemic Stroke in Oman
The goal of this study is to establish and examine the efficacy of using a Telestroke network in Oman to facilitate using emergent thrombolysis for patients with acute ischemic stroke encountered in selected peripheral hospitals.
- Trial name
- NCT07721129
- Testing
- alteplase or tenecteplase
- Volunteers
- 200 people
- Sponsor
- Oman Ministry of Health
Stroke
Motor Learning of a Planning Task in Stroke Patients: the Maze Paradigm Measured Through Time and Error as Variables
The purpose of this study is to investigate the process of acquiring a motor skill subject in post-stroke, comparing them with healthy subjects.
- Trial name
- NCT00740402
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Faculdades Metropolitanas Unidas
Acute Ischemic Stroke
Efficacy and Safety of AngongNiuhuang Pill for the Treatment of Patients With Acute Ischemic Stroke.
AngongNiuhuang pill has obvious effects on the cardiovascular and cerebrovascular, especially the cerebral vessels. Pharmacological experiments confirmed that AngongNiuhuang pill can protect blood-brain barrier, reduce capillary…
- Trial name
- AGNH2018 (NCT03733002)
- Testing
- AngongNiuhuang pill, Standard treatment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Acute Ischemic Stroke
Intra-arterial Hypothermic Magnesium Sulfate Infusion in Combination with Endovascular Thrombectomy in Acute Ischemic Stroke
The primary objective of this study is to estimate the safety of intra-arterial hypothermic magnesium sulfate infusion after endovascular thrombectomy in patients with acute ischemic stroke
- Trial name
- Hypo-Mag (NCT06760195)
- Testing
- Intra-arterial hypothermic magnesium sulfate infusion, Endovascular thrombectomy, Intravenous thrombolysis
- Where
- China
- Volunteers
- 6 people
- Sponsor
- Capital Medical University
Ischemic Stroke
Safety of Rt-PA + Transcranial Emission of Low-Energy Lasers for Acute Stroke Recovery
To assess the safety and preliminary efficacy of combining intravenous rt-PA with transcranial laser therapy (TLT) with the NeuroThera® Laser System (referred to hereafter as NTS) in subjects treated for acute ischemic stroke.
- Trial name
- StELLAR (NCT01220739)
- Testing
- Transcranial Laser Therapy
- Where
- 3 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of California, San Diego
Intracranial Aneurysm, Stent Complication
Stent-Assisted Coiling Followed by Ticagrelor Monotherapy Instead of Dual Antiplatelet Therapy in Unruptured Intracranial Aneurysm
The primary goal of the trial is to investigate whether the experimental arms (receiving the P2Y12 inhibitor Ticagrelor) compared with the control arm (taking dual antiplatelet therapy) could reduce bleeding complications in…
- Trial name
- SAC-TIDE (NCT06015477)
- Testing
- Ticagrelor monotherapy, Dual Antiplatelet Therapy
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Spinal Cord Injuries, Stroke
Wheelchair Cushion Comparison Study: SAFETY
Purpose: To examine the safety of the use of two wheelchair cushions for healthy individuals with intact sensation and individuals post stroke and spinal cord injury with impaired sensation.
- Conditions
- Spinal Cord Injuries, Stroke, Healthy Adults
- Trial name
- NCT03430375
- Testing
- Alternating air wheelchair cushion, Static air cushion
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Transient Ischemic Attack
Markers in the Diagnosis of TIA
MIND-TIA is primarily an observational diagnostic study that aims to evaluate the role of novel biomarkers in the diagnosis of Transient Ischemic Attack (TIA)in primary care.
- Trial name
- MIND-TIA (NCT01954329)
- Where
- Netherlands
- Volunteers
- 350 people
- Sponsor
- UMC Utrecht
Traumatic Brain Injury, Stroke
Traumatic Brain Injury and Stroke Long Term Outcome
Investigators will determine the long-lasting effects of post-acute rehabilitation after traumatic brain injury and stroke. Investigators will also evaluate if the beneficial effects of rehabilitation continue after discharge…
- Trial name
- NCT03399929
- Testing
- Post Acute Rehabiltation
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Centre for Neuro Skills
Ischemic Stroke
Prognostic Accuracy of ST2 Dynamics in Ischemic Stroke Outcome
Early outcome prediction after ischemic stroke (IS) is of great importance. Prognosis is usually based on clinical variables and neuroradiological findings while serum biomarkers may contribute to prognostic accuracy.
- Trial name
- ST2ROKE (NCT04607031)
- Testing
- measurement of serum ST2 concentrations in serum of patients with acute, ischemic stroke
- Where
- Croatia
- Volunteers
- 20 people
- Sponsor
- General Hospital Sveti Duh
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