Clinical trials: Cerebrovascular Disease
Hemiplegia And/or Hemiparesis Following Stroke
Evaluation of Positioning Protocols on a Wheelchair in Hemiplegic Patients
The main purpose of this study is to assess the interest of using wheelchair positioning equipment on the decrease of postural disorders, compared to the standard use of a wheelchair
- Trial name
- POSIT-HEMI (NCT04268641)
- Testing
- Arm 1, Arm 2, Arm 3
- Where
- 7 sites in France
- Volunteers
- 24 people
- Sponsor
- Hôpital NOVO
Stroke, Gait, Hemiplegic
The Effect of a Ankle Assist Robot on Gait Function and Cardiopulmonary Metabolic Efficiency in Stroke Patients
The aim of this study was to identify the assistance effect of Ankle Assist Robot v1 developed by Samsung Advanced Institute of Technology (Samsung Electronics Co, Ltd., Korea) by comparing 1.
- Trial name
- NCT03767205
- Testing
- Ankle Assist Robot
- Where
- South Korea
- Volunteers
- 45 people
- Sponsor
- Samsung Medical Center
Acute Ischemic Stroke, Neutrophil Extracellular Traps Formation
Sodium Sivelestat With Mechanical Thrombectomy for Acute Stroke: A Pilot Study
Stroke remains a major global health burden, with acute ischemic stroke (AIS) accounting for more than 65% of all cases. Endovascular thrombectomy (EVT) has been established as the standard treatment for large vessel occlusion…
- Conditions
- Acute Ischemic Stroke, Neutrophil Extracellular Traps Formation, Large Vessel Occlusion, Thrombectomy
- Trial name
- NCT07196605
- Testing
- Sodium Sivelestat
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke
Analysis of Brain Diffusion Tensor Image in Stroke Patients
This clinical study aims to confirm the characteristics of the functional ansiotropy value according to the individual characteristics of stroke patients by taking brain diffusion tensor images for stroke patients and using the…
- Trial name
- NCT06047223
- Testing
- Magnetic resonanace imaging
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Bundang CHA Hospital
Stroke, Meningioma
Robot-Assisted Neurovascular Intervention
Patients scheduled for neurovascular interventions may be eligible to have their procedure done robotically.
- Conditions
- Stroke, Meningioma, Neurovascular Disorder
- Trial name
- NCT06752096
- Testing
- cerebral angiography, arterial embolization, thrombectomy, Cerebral angiogram using robotic device, Meningioma embolization using robotic device.
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Navigantis Inc.
Ischemic Stroke, Stroke in the Young
Observational Dutch Young Symptomatic StrokE studY - nEXT
BACKGROUND: Worldwide, 2 million patients aged 18-50 years suffer an ischemic stroke each year with an increasing trend over the past decade due to yet unknown reasons.
- Conditions
- Ischemic Stroke, Stroke in the Young, Cardiovascular Diseases, Cerebrovascular Disorders
- Trial name
- ODYSSEY-nEXT (NCT05853796)
- Where
- 6 sites in Netherlands
- Volunteers
- 280 people
- Sponsor
- Radboud University Medical Center
Stroke, Fatigue
Post-stroke Fatigue, Inflammation, tDCS
Fatigue is a common condition after an individual has a stroke. While the negative impacts of post-stroke fatigue are well known, the knowledge of the causes of post-stroke fatigue and effective treatments for post-stroke fatigue…
- Conditions
- Stroke, Fatigue, Chronic Stroke, Stroke Sequelae
- Trial name
- NCT05330988
- Testing
- anodal transcranial direct current stimulation (a-tDCS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Acute Ischemic Stroke
Citicoline in Ischemic Stroke
There is evidence that citicoline is the only neuroprotectant able to improve the functional status of the patients after an acute ischemic stroke.
- Trial name
- NCT05154903
- Testing
- Citicoline 500 MG
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Ain Shams University
Stroke
The Whole Day Matters After Stroke (BIG-STEPS)
Goal of research program: To understand person-specific factors, such as imaging markers and activity patterns early after stroke, that may guide precision rehabilitation to optimize function and improve recovery. Objectives: 1.
- Trial name
- BIG-STEPS (NCT05753761)
- Testing
- Behaviour- & Imaging-Guided Stepping Training Early Post-Stroke (BIG STEPS) intervention
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Alberta
Hypoxic Ischemic Encephalopathy
MRI Thermal Imaging of Infants Undergoing Cooling for Hypoxic Ischemic Encephalopathy(HIE)
Hundreds of babies in the world are being treated with brain cooling to prevent brain injury after they lose oxygen at birth. This study will use the newly developed information from the magnet resonance image to determine the…
- Trial name
- NCT01128673
- Testing
- mRI
- Where
- United States
- Sponsor
- Vanderbilt University
Stroke, Ischemic, Stroke, Acute
Efficacy of Cerebrolysin Treatment as an add-on Therapy to Mechanical Thrombectomy in Acute Ischemic Stroke.
This study is designed to determine the efficacy and safety of Cerebrolysin treatment as an add- on therapy to mechanical thrombectomy (MT) in reducing global disability in subjects with acute ischemic stroke (AIS).
- Conditions
- Stroke, Ischemic, Stroke, Acute, Stroke Sequelae
- Trial name
- NCT04904341
- Testing
- Cerebrolysin
- Where
- Poland
- Volunteers
- 50 people
- Sponsor
- Military Institute od Medicine National Research Institute
Stroke
Impact of M-health Based Intervention on Adherence to Healthy Physical Activity After Stroke.
The aim of this study is to determine the impact of an m-health based intervention on long term adherence to a rehabilitation program for stroke survivors.
- Trial name
- NCT03507894
- Testing
- Multimodal Exercise Rehabilitation Program
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Consorci Sanitari de Terrassa
Acute Basilar Artery Occlusion, Endovascular Therapy
The Efficacy and Safety of Endovascular Therapy for Acute Ischemic Stroke Due to Large Core Infarction
This study assesses the efficacy and safety of endovascular therapy in patients with acute basilar artery occlusion with large core infarction within a multicenter, prospective, open-label, blinded endpoint, randomized controlled…
- Conditions
- Acute Basilar Artery Occlusion, Endovascular Therapy, Large Core Infarction
- Trial name
- NCT07333950
- Testing
- Endovascular Recanalization Strategy, Best Medical Management
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Beijing Tiantan Hospital
Late Onset Epilepsy, Stroke
Neurofrailty: A Study of Late-onset Epilepsy and Its Associations
There is not much known about why some people develop seizures in adulthood, but some researchers think that it might be a warning from the body to highlight something may be wrong with the brain.
- Conditions
- Late Onset Epilepsy, Stroke, Dementia
- Trial name
- NCT06263920
- Where
- United Kingdom
- Volunteers
- 360 people
- Sponsor
- Lancashire Teaching Hospitals NHS Foundation Trust
Cranial Diseases (e.g., Brain Tumors, Stroke, Neurodegenerative Disorders)
Construction of AI Model for Precision Imaging Diagnosis of Cranial Diseases
The goal of this observational study is to develop and validate a high-precision AI diagnostic model for cranial diseases by integrating clinical knowledge systems (pathophysiological classification, age stratification, and…
- Trial name
- NCT07446842
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Stroke
Lumbar Spinal Manipulation in Stroke
The aim of the study is to investigate the effects of lumbar spinal manipulation on balance and fall risk of the patients with chronic stroke.
- Trial name
- NCT07619586
- Testing
- Lumbar Spinal Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Bitlis Eren University
Carotid Artery Disease
Proximal Protection With The Mo.Ma Device During Carotid Stenting
The objective of the ARMOUR study is to evaluate the safety and effectiveness of the Mo.Ma proximal flow blockage cerebral protection device for patients at high surgical risk for carotid endarterectomy who undergo carotid artery…
- Trial name
- ARMOUR (NCT00744523)
- Testing
- Mo.Ma cerebral protection device
- Where
- 2 sites in United States
- Volunteers
- 262 people
- Sponsor
- Medtronic Endovascular
Stroke
Cognitive Motor Dual Task Versus Task Specific Training on Cognition and Motor Functioning in Stroke Patients
This study focuses on Dual Task Training as daily living involves many dual task conditions, in which a person requires to do two or more tasks at same time. without the ability to carry out these types of Dual movements.
- Trial name
- NCT06454279
- Testing
- Dual Task Training, Task Specific Training
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Carotid Stenosis
Histological Validation Of Carotid Plaque Composition In Preoperative Imaging
Patients scheduled for carotid endarterectomy undergo preoperative imaging to assess vulnerable plaque. The imaging modalities include (in various combinations at different study sites) 3-dimensional ultrasound, PET/CT imaging…
- Trial name
- NCT01456403
- Testing
- Histological validation
- Where
- 3 sites in Canada
- Volunteers
- 95 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Autoimmune Diseases, Non-small Cell Lung Cancer
Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer and Pre-existing Autoimmune Disease
The purpose of this study is to explore the safety, tolerability and activity of Nivolumab, a PD-1 inhibitor, in cohorts of patients with autoimmune disease.
- Conditions
- Autoimmune Diseases, Non-small Cell Lung Cancer, Rheumatoid Arthritis, Psoriasis
- Trial name
- NCT03656627
- Testing
- Nivolumab
- Where
- 9 sites in United States
- Volunteers
- 7 people
- Sponsor
- Alliance Foundation Trials, LLC.
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