Clinical trials: Cerebrovascular Disease
Strokes Thrombotic
Comparison Between the Efficacy of CIMT and NDT Along With Conventional Physiotherapy Treatment on Upper Extremity Rehabilitation Among Patients of Stroke
To compare the efficacy of CIMT and NDT among stroke patients To study the phenomena of transfer of training To study relationship between the MMSE score and stroke rehabilitation
- Trial name
- CIMT (NCT06485583)
- Testing
- Constraint-induced movement therapy, Neurodevelopmental Treatment
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Shalamar Institute of Health Sciences
Stroke
Multi-segmental Robotic and Technological Upper Limb Rehabilitation in Stroke
Stroke is frequently associated with significant disability and impaired quality of life. Persistent motor impairment is common with often incomplete recovery of motor function in response to rehabilitation, mainly in the upper…
- Trial name
- NCT02879279
- Testing
- Amadeo, Pablo, Diego and Motore., Conventional rehabilitation
- Where
- Italy
- Volunteers
- 247 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Intra-operative Hypotension, Carotid Stenosis
Effect of Blood Pressure on rSO2 in Carotid Endarterectomy (CEA)
Carotid endarterectomy (CEA) is the recommended treatment for symptomatic high degree stenosis of the internal carotid artery (ICA).
- Trial name
- NCT01451294
- Testing
- Administration of phenylephrine, Administration of ephedrine
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- G.J. de Borst
Ischemia Stroke, Thrombectomy
Intra-arterial Methylprednisolone After Endovascular Thrombectomy
The purpose of IMPACT-LVO trial is to investigate the efficacy and safety of early adjunctive intra-arterial combined with intravenous administration methylprednisolone sodium succinate after successful endovascular thrombectomy…
- Conditions
- Ischemia Stroke, Thrombectomy, Large Vessel Occlusion
- Trial name
- IMPACT-LVO (NCT07516522)
- Testing
- The methylprednisolone sodium succinate group
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Tang-Du Hospital
Dsyphagia After Stroke
Oral Status as Predictors of Stroke-Associated Pneumonia and Swallowing Recovery in Patients With Post-Stroke Dysphagia
Post-stroke dysphagia (PSD) is a common condition that significantly impacts recovery and increases the risk of complications such as pneumonia, malnutrition, and prolonged hospital stays.
- Trial name
- NCT07059351
- Where
- Belgium
- Volunteers
- 260 people
- Sponsor
- University Hospital, Ghent
Stroke
Functional Impact of a Closed-loop Controlled Grasping Neuroprosthesis in Post-stroke Patients (PREHENSTROKE)
Stroke is the leading cause of disability in adults. The improvement of the grasp abilities remains a challenge in the 50% of post-stroke subjects who have not recovered functional grasping due to paralysis of the finger's…
- Trial name
- PREHENSTROKE (NCT03946488)
- Testing
- Functional electrical stimulation
- Where
- 2 sites in France
- Volunteers
- 11 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Hemianopia, Hemianopsia
Rehabilitating Visual Deficits Caused by Stroke
This research aims to understand the efficacy of a visual training task to improve visual loss after stroke, also known as hemianopia.
- Conditions
- Hemianopia, Hemianopsia, Quadrantanopia, Stroke Induced Vision Loss
- Trial name
- NCT04878861
- Testing
- Training in the blind field
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Alzheimer Disease, Vascular Dementia
A Study of the Safety and Effectiveness of Galantamine Versus Placebo in the Treatment of Patients With Vascular Dementia or Mixed Dementia
The purpose of this study is to evaluate the safety and efficacy of galantamine (a drug for treating dementia) compared to placebo in the treatment of patients with dementia related to cerebrovascular disease (vascular dementia)…
- Trial name
- NCT00261573
- Testing
- galantamine hydrobromide
- Volunteers
- 593 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Atrial Fibrillation, Stroke, Ischemic
Atrial Fibrillation Burden and Long-term Risk of Thromboembolic Complications- the FinCV-4 Study
This study explores the association of symptomatic episodes of atrial fibrillation (AF) occurrence and long-term risk of thromboembolic complications in a retrospective setting.
- Trial name
- FinCV-4 (NCT04001205)
- Testing
- Anticoagulation Therapy
- Where
- Finland
- Volunteers
- 1,300 people
- Sponsor
- University of Turku
Stroke
The Effect of Optic Flow Speed Manipulation and the Level of Immersion on the Gait Pattern in People Post-stroke
The aim of this study is to investigate the effect of manipulating the optic flow speed in the virtual environment on the gait pattern during virtual reality (VR) - enhanced treadmill walking in people post-stroke.
- Trial name
- NCT04521829
- Testing
- Walking with different optic flow speeds with 2 different VR devices
- Where
- Belgium
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Stroke
Effects of Robot-Assisted Upper Extremity Training on Cognitive and Physical Functions After Stroke
Stroke is a main cause of disability worldwide. It is characterized by motor and cognitive impairments leading to activity limitations and participation restrictions.
- Trial name
- NCT04335422
- Testing
- Robotic group (Upper extremity robot-assisted training plus routine physical and rehabilitation medicine program), Control group (routine physical and rehabilitation medicine program)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara University
Cardiovascular Diseases, Heart Diseases
Pawtucket Heart Health Program
To conduct a community-based research and demonstration project in cardiovascular disease prevention in the town of Pawtucket, Rhode Island.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypercholesterolemia, Hypertension
- Trial name
- NCT00005151
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Chronic Subdural Hematoma, Hemorrhage Brain
Microfabricated Microcatheter Advantages in Middle Meningeal Artery Embolization: an Early Experience at a Single Center
The purpose of this study is to evaluate the function of matched pair Aristotle 14 Guidewire and Plato Microcatheter in MMA embolization treatment for chronic subdural hematoma compared to surgeon's preference
- Trial name
- SCIENTIA (NCT07324551)
- Testing
- Matched pair Aristotle 14 guidewire and Plato 17 microcatheter, Surgeon combination preference
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Stroke
The Effects of Whole Body Vibration in People With Chronic Stroke
Whole body vibration (WBV) has been found to be useful in promoting bone health and muscle performance in older adults. To date, no study has examined the effects of different WBV frequencies on the properties of the muscle-bone…
- Trial name
- NCT03982251
- Testing
- High frequency whole body vibration, Low frequency whole body vibration
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stroke, Hemiplegia
Robot-Assisted Therapy in Chronic Stroke Patients
Considering the paucity of studies on robotic hand therapy, larger-scale and long-term follow-up studies are needed. The aim in this study is to demonstrate the effectiveness of robot-assisted hand therapy in patients with…
- Trial name
- NCT06692829
- Testing
- robotic rehabilitation, conventional rehabilitation
- Volunteers
- 80 people
- Sponsor
- Afyonkarahisar Health Sciences University
Basal Ganglia Hemorrhage
A Trial for Minimally Invasive Neurosurgery With AI-assisted Robotic Guidance for Moderate Basal Ganglia Hemorrhage (RAINBOW-MBH)
A nationwide, prospective, multicenter randomized controlled clinical trial to evaluate the therapeutic effects of the fiber tract-based artificial intelligence (AI) Robot Guiding System on the perioperative and long-term…
- Trial name
- RAINBOW-MBH (NCT06465719)
- Testing
- Minimally invasive basal ganglion hematoma evacuation with Tract-based AI Robot Guiding System, Patients will be managed with guideline-based medications
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Arm Motor Recovery
Repetitive Arm Training + FES on Upper Extremity Motor Recovery in Sub-acute Stroke Survivors
Rehabilitation restores functions and reduces disabilities due to diseases sequelae. The relationship between intensity of rehabilitation and clinical outcomes, recently emphasized, has generated a great interest for…
- Trial name
- NCT02267798
- Testing
- conventional therapy, arm training combined with FES
- Where
- 2 sites in Italy
- Volunteers
- 64 people
- Sponsor
- University Hospital of Ferrara
Cerebrovascular Stroke
Randomized Study Comparing Periodic Acceleration Versus Static Position in Cerebrovascular Stroke Patients
Stroke is one of the leading causes of death and disability worldwide. More than 85% of strokes are due to blood vessel occlusion resulting in partial destruction of the brain parenchyma.
- Trial name
- NCT02038998
- Testing
- Exer-Rest® TL
- Where
- Spain
- Sponsor
- Fundacion Rioja Salud
Ischemic Stroke
Trial of Mongolian Medicine ZhenBao Pills for Upper-limb Dysfunction After Stroke
The trial was designed to test the hypothesis that treatment with Mongolian Medicine ZhenBao Pills has a positive effect on upper-limb motor recovery after acute ischemic stroke.
- Trial name
- PEARL (NCT06049498)
- Testing
- Mongolian Medicine ZhenBao Pills
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Dongzhimen Hospital, Beijing
Basilar Artery Occlusion
Contact Aspiration Versus Stent Retriever for Recanalisation of Acute Stroke Patients With Basilar Artery Occlusion: The Posterior Circulation ASTER Randomized Trial Protocol
Acute ischemic stroke (AIS) patients with basilar artery occlusion (BAO) present a devastating, life-threatening prognosis. Urgent recanalization with endovascular mechanical thrombectomy is routinely performed in patients with…
- Trial name
- pc-ASTER (NCT05320263)
- Testing
- Contact aspiration Thrombectomy, Stent retriever thrombectomy
- Where
- 12 sites in France
- Volunteers
- 480 people
- Sponsor
- Hopital Foch
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