Clinical trials: Cerebrovascular Diseases
Sepsis
Pathogenesis and Cerebrovascular Manifestations of Septic Encephalopathy
Septic encephalopathy is an important complication of sepsis. Why some patients with sepsis develop septic encephalopathy is unknown.
- Trial name
- NCT00410111
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University Hospital, Basel, Switzerland
Acute Ischemic Stroke
Acute Ischemic Stroke Interventional Study
To assess safety of single IV (bolus + infusion) doses of ACT017 in patients with an acute ischemic stroke in addition to best emergency standard of care (including fibrinolysis by rtPA with or without added thrombectomy), with a…
- Trial name
- ACTIMIS (NCT03803007)
- Testing
- Intravenous ACT017 1000 mg
- Where
- France
- Volunteers
- 160 people
- Sponsor
- Acticor Biotech
Ischemic Stroke
Early Antiplatelet for Minor Stroke Following Thrombolysis (EAST)
The current guideline recommends to give antithrombotic treatment 24 hours after intravenous thrombolysis in acute ischemic stroke.
- Trial name
- NCT05193071
- Testing
- Aspirin 100mg; Clopidogrel 300mg
- Where
- 2 sites in China
- Volunteers
- 1,022 people
- Sponsor
- General Hospital of Shenyang Military Region
Stroke
Gait Control of Stroke Patients Using Visual Feedback
The purpose of this study is to determine the possibility of gait pattern change via visual feedback among patients with stroke. Also, the optimal visual feedback would be chosen from this study.
- Trial name
- NCT02029664
- Testing
- Visual distortion increment based on the gait pattern
- Where
- South Korea
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Aortic Valve Stenosis, Stroke
Oxygenation of the Cerebrum and Cooling During Transcatheter Aortic Valve Implantation (TAVI) Procedures - Part II
The aim of this study is to assess the possible neuroprotective effects of cooling (targeted cooling of the brain to 33°C) during Transcatheter Aortic Valve Implantation (TAVI) procedures.
- Trial name
- NCT01822964
- Testing
- targeted brain cooling (33°C) by RhinoChill device
- Where
- 2 sites in Belgium
- Volunteers
- 30 people
- Sponsor
- Hasselt University
Stroke
Physiotherapy and Action-Observation Therapy: An Integrated Approach for Upper Limb Impairment in Subacute Stroke
Motor impairment is one of the most common result of a stroke, which causes disability and difficulties in activities of daily living. This motor impairment can concern the upper limb or the lower limb, or both.
- Trial name
- PHOENICS (NCT04560764)
- Testing
- Virtual Reality, Action Observation Therapy, Landscape video
- Where
- Italy
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Stroke, Intracranial Atherosclerotic Stenosis
SeQuent ® Please CIS for the Treatment of INtracranial Atherosclerotic Stenosis
This study is aiming to evaluate the safety and efficacy of SeQuent® Please CIS in the endovascular treatment of symptomatic intracranial atherosclerotic stenosis and restenosis after interventional therapy.
- Trial name
- SPINAS (NCT06047964)
- Testing
- DCB, POBA
- Where
- 9 sites in China
- Volunteers
- 281 people
- Sponsor
- B. Braun Medical International Trading Company Ltd.
Stroke
Study on the Accuracy of Determining the Responsible Vessel in Medium Vessel Occlusive Stroke Based on Multi-type CT Evaluation
To evaluate the accuracy of diagnosing the qualifying artery in patients with medium vessel occlusion stroke based on multimodal CT
- Trial name
- NCT07347587
- Where
- China
- Volunteers
- 622 people
- Sponsor
- Xuanwu Hospital, Beijing
Acute Stroke
Evaluation of the Intravenous Tissue Plasminogen Activator Treatment Algorithm of Nursing Intern Students
Intravenous (IV) tissue plasminogen activator (tPA) is one of the key elements of acute ischemic stroke. In this study, acute stroke patients maximum benefit from the treatment, intravenous tissue plasminogen activator (IV tPA)…
- Trial name
- NCT05462665
- Testing
- theory training, theory and simulation training
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Dokuz Eylul University
Antiphospholipid Syndrome, Systemic Lupus Erythematosus
RIvaroxaban for Stroke Patients With AntiPhospholipid Syndrome
Rivaroxaban versus warfarin for stroke patients with antiphospholipid syndrome, with or without SLE (RISAPS): a randomised, controlled, open-label, phase IIb, non-inferiority proof of principle trial.
- Conditions
- Antiphospholipid Syndrome, Systemic Lupus Erythematosus, Stroke, Ischemic Stroke
- Trial name
- RISAPS (NCT03684564)
- Testing
- Rivaroxaban, Warfarin
- Where
- 6 sites in United Kingdom
- Volunteers
- 43 people
- Sponsor
- University College, London
Aphasia, Apraxia of Speech
Treatments of Acquired Apraxia of Speech
This study was designed to examine the effects of speech therapy on ability to produce speech sounds in persons with acquired apraxia of speech.
- Conditions
- Aphasia, Apraxia of Speech, Stroke
- Trial name
- Apraxia (NCT01483807)
- Testing
- Sound Production Treatment - Blocked, Sound Production Treatment - Random
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Stroke, Obstructive Sleep Apnea
Role of Obstructive Sleep Apnea in Stroke Appearance
Stroke is the third leading cause of death in industrialized countries and the first cause of handicap in adults. Several stroke risk factors were identified such as high blood pressure, diabetes mellitus, hypercholesterolemia or…
- Trial name
- AVSAS (NCT00613522)
- Testing
- polygraphic study
- Where
- France
- Volunteers
- 289 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Disorder of Consciousness, Stroke
Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases
The goal of this clinical trial is to evaluate the efficacy of a musical interventionand non-invasive brain stimulation in neurological patients.
- Trial name
- NCT05706831
- Testing
- Combinatory effect of music stimulation and neurostimulation
- Where
- Italy
- Volunteers
- 90 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Stroke, Hemiplegia
Effects of Theta Burst Stimulation on Modulation of Mirror Illusion-induced Rhythm Suppression in Stroke
The study aims to test the hypothesis that rTMS in the form of theta burst stimulation (TBS) over the ipsilateral and contralateral motor cortices can modulate mirror illusion-induced rhythm suppression while observing unilateral…
- Trial name
- NCT04658745
- Testing
- Intermittent theta burst stimulation, Mirror Therapy
- Where
- Hong Kong
- Volunteers
- 36 people
- Sponsor
- The Hong Kong Polytechnic University
Cerebrovascular Stroke, Body Composition
Assessment of Body Composition, Fatigue, Mobility and Functional Status in Post-Stroke Individuals
The goal of this randomized controlled trial is to evaluate body composition, fatigue, mobility level, functional status in with stroke individuals.
- Trial name
- NCT06255145
- Testing
- Bioelectrical Impedance Analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Atrial Fibrillation, Ischemic Stroke
Atrial Fibrillation in Cryptogenic Stroke and TIA
Background: Different studies with real-life data and randomized controlled trials have shown a detection rate of paroxysmal atrial fibrillation (AF) of 10-20% in patients with cryptogenic stroke using insertable continuous…
- Conditions
- Atrial Fibrillation, Ischemic Stroke, TIA
- Trial name
- NOR-FIB (NCT02937077)
- Testing
- Medtronic Reveal LINQ
- Where
- 2 sites in Norway
- Volunteers
- 259 people
- Sponsor
- Oslo University Hospital
Stroke, Hemiplegia
The Effect of Virtual Reality Treadmill-Based Gait Training on Gait and Balance Ability in Chronic Stroke Patients
Walking independence is one of the most important goals for stroke patients and a major factor influencing their return to society after the onset of stroke.
- Trial name
- NCT06557681
- Testing
- Virtual Reality-Treadmill Training Group (VTT), Conventional Therapy Group (CT)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Yonsei University
Metabolic Disease, Fabry Disease
Getting Global Rare Disease Insights Through Technology Study
This project is a randomized controlled trial to use a mobile health journal, called Zamplo (formerly known as MyHealthJournal or ZoeInsights), to record patient reported outcomes (PROM) in patients with metabolic disorders.
- Conditions
- Metabolic Disease, Fabry Disease, Gaucher Disease, Pompe Disease
- Trial name
- GRIT (NCT04758130)
- Testing
- Zamplo Digital Health Platform
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- M.A.G.I.C. Clinic LTD
Intracranial Aneurysm, Abdominal Aortic Aneurysm
UVA Brain and Aortic Aneurysm Study
The purpose of this study is to examine the percentage of patients who present with abdominal aortic aneurysms (AAA) will also have intracranial aneurysms (IA) and conversely; to examine the percentage of patients who present…
- Trial name
- BAAS (NCT02869464)
- Testing
- Imaging-Ultrasound, Imaging-MRA, DNA, RNA testing
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of Virginia
Cardiovascular Diseases, Heart Diseases
Minnesota Heart Survey - Risk Factor Survey
To continue surveillance of cardiovascular disease risk factors in the seven-county area of Minneapolis-St. Paul.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Cerebrovascular Accident, Coronary Disease
- Trial name
- MHS (NCT00005145)
- Sponsor
- University of Minnesota
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