Clinical trials: Cerebrovascular Diseases
Stroke, Atrial Fibrillation
HEart and BRain Interfaces in Acute Ischemic Stroke
The primary aim of this prospective observational study is to investigate whether an enhanced diagnostic MRI work-up (including cardiac MRI, angiography of the aortic arch and the brain-supplying arteries) combined with an…
- Trial name
- HEBRAS (NCT02142413)
- Where
- Germany
- Volunteers
- 368 people
- Sponsor
- Charite University, Berlin, Germany
Alzheimer's Disease, Vascular Dementia
BAC in Patient With Alzheimer's Disease or Vascular Dementia
The primary objective of this study is to evaluate the efficacy of BAC patients with Alzheimer's disease or vascular dementia.The secondary objective of this study is to evaluate the safety of BAC patients with Alzheimer's…
- Trial name
- NCT02467413
- Testing
- BAC, BAC Matched Vehicle
- Where
- Taiwan
- Sponsor
- Botanicure Co., Ltd.
Stroke, Shoulder Dislocation or Subluxation
Effect of High Intensity Laser on Hemiplegic Shoulder Dysfunction
Hemiplegic shoulder pain (HSP) is a common and disabling complication following a stroke, and it may affect the quality of life. It often occurs following two to three months of stroke.
- Trial name
- NCT05595720
- Testing
- hight intenisty laser
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Deraya University
Stroke, Physical Inactivity
How Stroke Affects Leg Muscles When Walking
Stroke is the leading cause of acquired disability in France and the third leading cause worldwide. This research will : Test how reliable current medical methods are for measuring muscle activity.
- Conditions
- Stroke, Physical Inactivity, Spasticity, Muscle, Walking, Difficulty
- Trial name
- MCOACT (NCT07504627)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Limoges
Stroke
Development of an Intelligent Balance Training System Providing Weight-bearing Feedback in Stroke Patients
The sit-to-stand and dynamic weight-shifting ability of stroke patients is highly associated with walking performance. Therefore, in order to improve the dynamic weight-shifting ability in sit-to-stand and parallel or tandem…
- Trial name
- NCT04841161
- Testing
- Balance function, gait ability, weight- distribution and weight-shifting, Weight- distribution and weight-shifting training program
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Cerebrovascular Accident
Evaluating the Remote Effects of Stroke With MRI and PET Scans
Patients with stroke sometimes have a condition called diaschisis, a loss of function in a part of the brain located some distance from the original stroke-injury site. Doctors do not know why this happens.
- Trial name
- NCT00063180
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Intracerebral Hemorrhage
Minimally Invasive Surgery Plus Rt-PA for ICH Evacuation Phase III
A phase III, randomized, case-controlled, open-label, 500-subject clinical trial of minimally invasive surgery plus rt-PA in the treatment of intracerebral hemorrhage (ICH).
- Trial name
- MISTIE-III (NCT01827046)
- Testing
- rt-PA
- Where
- 84 sites in United States, Australia and 7 more
- Volunteers
- 499 people
- Sponsor
- Johns Hopkins University
Stroke
Clinical Effects of Brain Machine Interface in Chronic Stroke Patient
Determination of clinical effects of brain machine interface in chronic stroke patient without wrist extensor strength
- Trial name
- NCT04451941
- Testing
- Experimental: RecoveriX with individual EEG calibration, RecoveriX without individual EEG calibration
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- National Rehabilitation Center, Seoul, Korea
Chronic Kidney Diseases
Cerebrovascular Dysregulation in Chronic Kidney Disease
The purpose of this study is to test whether or not regular exercise training may improve brain blood flow regulation in patients with chronic kidney disease (CKD).
- Trial name
- NCT05571605
- Testing
- Exercise, Stretching
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of North Texas, Denton, TX
Stroke, Cardiovascular Diseases
MIDNOR-STROKE- a Long Term Follow-up Study of Patients With First Ever Ischemic Stroke in Central Norway
Annually 13000 Norwegians experience an ischemic stroke. The number of stroke is anticipated to increase with 50% within 2030 due to a growing number of elderly.
- Conditions
- Stroke, Cardiovascular Diseases, Cardiovascular Risk Factor, Brain Ischemia
- Trial name
- NCT03962127
- Testing
- no intervention
- Where
- 8 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Norwegian University of Science and Technology
Rheumatoid Arthritis, Giant Cell Arteritis
Comparative Study of 3 Tocilizumab Products in Normal Healthy Volunteeers
A single dose, two period trial where participants will be given either of 3 Tocilizumab product on Day 1 during period 1 and either one of the remaining 2 Tocilizumab products on Day 1 period 2.
- Trial name
- NCT04885829
- Testing
- Tocilizumab Prefilled Syringe
- Where
- 4 sites in Australia, India and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Syneos Health
Carotid Artery Disease
A Carotid Stenting Boston Scientific Surveillance Program
CABANA is a multicenter U.S. surveillance registry that will be conducted to compile early clinical outcomes data for the Carotid WALLSTENT Endoprosthesis and FilterWire EZ System in routine clinical practice and to assess the…
- Trial name
- CABANA (NCT00741091)
- Testing
- Carotid WALLSTENT Monorail Endoprosthesis, FilterWire EZ™ System™
- Where
- 112 sites in United States
- Volunteers
- 1,097 people
- Sponsor
- Boston Scientific Corporation
Stroke
Effect of Sensorimotor Training Versus Dual-task Training
The aim of this study is to determine the comparative effects of sensorimotor training and dual-task training on propriocetion, balance, functional mobility and fall risk in stroke patients.
- Trial name
- NCT07628374
- Testing
- Sensorimotor Training, Dual-Task Training, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Stroke
Swipe Out Stroke (SOS): Feasibility of Using a Consumer Based Electronic Application to Improve Compliance With Weight Loss in Obese Minority Stroke Patients
This pilot study evaluates the use of a mobile application to improve weight loss in obese stroke patients. The investigators hypothesize that acute stroke patients who use the mobile application are more likely to achieve a…
- Trial name
- SOS (NCT02531074)
- Testing
- Mobile Application, Food Journal, Usual Care
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Dysphagia
Auricular Vagus Nerve Stimulation and Post-Stroke Dysphagia in Older Adults
This study investigates the effect of non-invasive transcutaneous auricular vagus nerve stimulation (tVNS-E) on swallowing rehabilitation in patients over 70 years old after stroke.
- Trial name
- SVA-DPA (NCT07428590)
- Testing
- tVNS-E active device, tVNS-E inactive device
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Aphasia, Broca
Effects of MTS-r on Speech Production in Non-fluent Aphasia Post-ischemic Stroke Patients
Aphasia is one of the most disabling complications in language production in patients with left hemisphere stroke. About 19% of patients who experience aphasia may have a spontaneously recovery after several weeks or months.
- Trial name
- Aphasia-ACV (NCT02241213)
- Testing
- Transcranial Magnetic Stimulation (TMS-r)
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Fundación Cardiovascular de Colombia
Stroke
Neuroprotection With Statin Therapy for Acute Recovery Trial (Neu-START)
The purpose of this dose escalation study is to evaluate the use of lovastatin for the treatment of acute ischemic stroke.
- Trial name
- Neu-START (NCT00243880)
- Testing
- lovastatin
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Columbia University
Stroke, Cerebrovascular
Clinical Development of a Tool for Optimized Self- and Hetero-diagnosis of Stroke Using Artificial Intelligence: Stage1- Collection of Video-clinical Data in a Pragmatic Situation.
The study authors aim to form a collection of video-clinical data in a pragmatic situation to enable the development of relevant AI algorithms (for both hetero- and self-diagnosis modes).
- Trial name
- PREDISTROKE (NCT05959746)
- Testing
- AI-STROKE application
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke, Stroke, Ischemic
Individual Patient Expanded Access IND for the Treatment of Stroke
This protocol is part of an Individual Patient Expanded Access IND. The patient is an 84-year-old male with history of Ischemic Stroke of the Left Middle Cerebral Artery causing an acute posterior left frontal cortical infarct…
- Trial name
- NCT04907188
- Testing
- HB-adMSCs
- Where
- United States
- Sponsor
- Hope Biosciences Research Foundation
Spasticity, Dry Needling
Additional Effects of Dry Needling With PNF on Spasticity and Functional Performance in Stroke
Stroke is a prevalent cause of long-term disability, with a rising global incidence. Stroke patients commonly experience impaired balance and trunk control, which limits their daily activities and quality of life.
- Conditions
- Spasticity, Dry Needling, Functional Performance
- Trial name
- NCT07013942
- Testing
- Dry Needling Group
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Foundation University Islamabad
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