Clinical trials: Cerebrovascular Diseases
Depression
Single-Dose Pharmacokinetics (PK) Study of Novel Neurogenic Compound NSI-189
This is a subject single blinded, randomized, placebo-controlled, single dose, first-time-in-human study with three or more ascending cohorts.
- Trial name
- NCT01310881
- Testing
- NSI-189 Phosphate
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Neuralstem Inc.
Acute Ischemic Stroke
Intravenous N-Acetylcysteine for the Treatment of Acute Ischemic Stroke
Stroke is a major cause of death and long-term disability in the developed world. While t-PA and mechanical thrombectomy have been shown to decrease disability in properly selected patients, many patients are left with lifelong…
- Trial name
- NCT04918719
- Testing
- Acetylcysteine, Dextrose in Water
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Stroke
Families In Recovery From Stroke Trial (F.I.R.S.T.)
The purpose of this trial is to assess the effects of a psychosocial intervention on functional recovery after stroke.
- Trial name
- NCT00037492
- Testing
- home-based sessions/family meetings with trained clinician
- Where
- 6 sites in United States
- Volunteers
- 291 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Acute, Stroke
Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke
Stroke is the leading cause of activity limitation among older adults in the United States. NeuroMuscular Electrical Stimulation (NMES) can assist stroke survivors in regaining motor ability and decreasing activity limitation…
- Conditions
- Stroke, Acute, Stroke, Hemiparesis
- Trial name
- NCT00142792
- Testing
- NMES device with EMG-triggered and Cyclic capabilities
- Where
- 3 sites in United States
- Volunteers
- 122 people
- Sponsor
- MetroHealth Medical Center
Stroke
Combining Transcranial Direct Current Stimulation With Intermittent Oral to Esophageal Tube for Stroke-related Dysphagia
The study is a double-blind randomized controlled trial, lasting for 15 days for each participant. Patients with post-stroke dysphagia who receive treatment at the Rehabilitation Department are selected as the study subjects.
- Trial name
- NCT06329011
- Testing
- Comprehensive rehabilitation therapy, Intermittent Oro-esophageal Tube Feeding, Transcranial direct current stimulation
- Volunteers
- 80 people
- Sponsor
- Copka Sonpashan
Carotid Stenosis
Efficacy and Outcome of Carotid Endarterectomy for Symptomatic Carotid Stenosis
Neurovascular complications can result from this procedure usually from thromboembolism from the operated vessel, cerebral hypoperfusion causing ischaemia and, rarely, intracerebral haemorrhage.
- Trial name
- NCT06756360
- Volunteers
- 25 people
- Sponsor
- Assiut University
Acute Stroke
Comparing Transcranial Direct Current Stimulation Montages in Stroke
40 acute subjects will be split into 5 groups. Each group will receive one of the following tDCS montages : anodal, bilateral, cathodal, extracephalic or placebo.
- Trial name
- NCT04340973
- Testing
- Transcranial Direct Current Stimulation
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- University of Liege
Stroke Recurrence, Transient Ischemic Attack
Prevent Return of Stroke Study
The purpose of this study is to evaluate if a peer-led stroke recurrence prevention intervention, versus usual care, will help reduce risk factors for recurrent strokes among adults in Harlem.
- Trial name
- NCT01027273
- Testing
- Prevent Return of Stroke
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Strokes Thrombotic
Comparison Between the Efficacy of CIMT and NDT Along With Conventional Physiotherapy Treatment on Upper Extremity Rehabilitation Among Patients of Stroke
To compare the efficacy of CIMT and NDT among stroke patients To study the phenomena of transfer of training To study relationship between the MMSE score and stroke rehabilitation
- Trial name
- CIMT (NCT06485583)
- Testing
- Constraint-induced movement therapy, Neurodevelopmental Treatment
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Shalamar Institute of Health Sciences
At Risk for AD-dementia, With Subjective Cognitive Decline, At Risk for Cognitive Decline
High-Velocity Resistance Training for Brain Blood Flow and Cognitive Function in Older Adults
The goal of this clinical trial is to learn whether a 12-week high-velocity resistance training program can improve brain blood flow and thinking skills in adults ages 60 to 79 who are at higher risk for Alzheimer's disease and…
- Trial name
- NCT07444554
- Testing
- High-Velocity Resistance Training
- Volunteers
- 60 people
- Sponsor
- University of Illinois Chicago
Cerebrovascular Accident
tDCS and Physical Therapy in Stroke
The purpose of this study is to determine whether a painless and noninvasive procedure called transcranial direct current stimulation (tDCS) combined with a method of physical therapy called constraint-induced movement therapy…
- Trial name
- NCT00542256
- Testing
- Active transcranial Direct Current Stimulation / Constraint Induced Movement Therapy
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Beth Israel Deaconess Medical Center
Stroke, Stroke Hemorrhagic
Task-Specific Self-Rehabilitation Training (TASSRET) Trial
The goal of this pilot RCT is to evaluate the effectiveness of a Task-specific Self-rehabilitation Training (TASSRET) program and compare the effect of the two formats of the TASSRET (video vs manual) on functional ability (upper…
- Conditions
- Stroke, Stroke Hemorrhagic, Stroke Ischemic, Hemiparesis After Stroke
- Trial name
- TASSRET (NCT07208422)
- Testing
- Video-based Task-specific Training, Manual-based Task-specific Training
- Where
- Nigeria
- Volunteers
- 50 people
- Sponsor
- National Assembly Clinic
Brain Ischemia
Mild Hypothermia in Acute Ischemic Stroke
Hypothesis: Mild hypothermia using non-invasive temperature management system in a stroke unit is safe and feasible in spontaneously breathing, alteplase-thrombolyzed patients with acute ischemic stroke.
- Trial name
- NCT00987922
- Testing
- Hypothermia
- Volunteers
- 36 people
- Sponsor
- University of Helsinki
Spatial Neglect, Dysphagia
Identifying and Treating Arousal Related Deficits in Neglect and Dysphagia
The purpose of this study is to examine how stroke can alter arousal, alertness, neglect and dysphagia, and whether a medication, modafinil, can improve arousal.
- Trial name
- NCT01085903
- Testing
- Modafinil, Baseline, CPS
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- University of Arkansas
Stroke
Strength Training for Skeletal Muscle Adaptation After Stroke
Chronically disabled stroke survivors experience accelerated skeletal muscle atrophy and other detrimental changes to muscle and surrounding tissues on the paretic side.
- Trial name
- NCT00827827
- Testing
- Exercise- Strength Training, Exercise- Stretching Control
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Stenoses, Carotid Artery
Selective Versus Routine Shunting in Carotid Endarterectomy Patients
The project involves prospectively randomizing patients to either routine carotid shunting or selective carotid shunting during Carotid endarterectomy (CEA) under general anesthesia (GA) to see the difference in post-op…
- Trial name
- NCT00967486
- Testing
- Carotid endarterectomy with routine shount, Carotid endarterectomy with selective shunt
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
Carotid Artery Disease
Carotid Artery Stenting With Emboli Protection Surveillance-Post-Marketing Study (CASES-PMS)
The primary objective of this study is to assess the outcomes of stenting with distal protection in the treatment of obstructive carotid artery disease during peri-approval/initial commercialization in relation to the outcomes of…
- Trial name
- NCT00231231
- Testing
- -PRECISE Nitinol Stent System (5F, 5.5F and 6F), ANGIOGUARD™ XP Emboli Capture Guidewire (ECGW)
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- Cordis US Corp.
Ischemic Stroke, Transient Ischemic Attack
Empowerment and Mobile Technology in the Control of Cardiovascular Risk Factors in Patients With Ischemic Stroke
The CARDIOSTROKE is a randomized trial comparing mobile-device assisted control of hypertension together with screening of occult atrial fibrillation to standard care in patients with recent ischemic stroke or transient ischemic…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Atrial Fibrillation, Hypertension
- Trial name
- CARDIOSTROKE (NCT03710902)
- Testing
- ECG monitoring for 3 weeks, Self-monitoring of BP and self-titration of antihypertensive medication
- Where
- 4 sites in Finland
- Volunteers
- 405 people
- Sponsor
- Jukka Putaala
Acute Stroke
Mechanical Recanalization With Flow Restoration in Acute Ischemic Stroke
The objective of this study is to collect data on the use of the SOLITAIR FR device for treatment of acute ischemic stroke with large artery occlusion i.e.
- Trial name
- ReFlow (NCT01210729)
- Testing
- Solitaire FR, ev3
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Universität des Saarlandes
Stroke
Kinesiophobia and Balance in Stroke Patients
This is a cross-sectional clinical study planned to include 138 stroke patients receiving inpatient treatment at the Istanbul Physical Therapy and Rehabilitation Training and Research Hospital.Data on kinesiophobia (Tampa…
- Trial name
- NCT07241429
- Testing
- Survey using a questionnaire.
- Where
- Turkey (Türkiye)
- Volunteers
- 138 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.