Clinical trials: Cerebrovascular Diseases
Hematoma, Subdural Hematoma
Patient Registry for Patients With Chronic Subdural Hematoma
All admitted patients diagnosed with unilateral or bilateral chronic subdural hematoma are included into this registry after consent.
- Conditions
- Hematoma, Subdural Hematoma, Chronic
- Trial name
- CSDH-R (NCT04170582)
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Stroke
Art-based Activities in Stroke Patients
Introduction and Aim: Life after stroke begins a difficult period in which functional capacity is very limited. Disability persists for a long time, and various problems such as hemiparesis, hemiplegia, dysarthria, dysphagia…
- Trial name
- NCT06380959
- Testing
- Art Based Activity
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ege University
Hypothermia, Stroke, Acute
Short-duration Selective Brain Cooling for Patients Undergoing Mechanical Thrombectomy
To determine the efficacy and safety of short-duration intra-artery selective brain cooling in addition to mechanical thrombectomy in patients with acute ischemic stroke.
- Trial name
- NCT03163459
- Testing
- selective brain cooling by cold saline perfusion, mechanical thrombectomy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Capital Medical University
Acute Inflammatory Demyelinating Polyradiculoneuropathy, Stroke
Processing Integration in Neurological Patients Using fMRI
The main objective of the study is to explore and map brain areas involved in processing and perception in patients suffering from neurological pathologies and condition.
- Conditions
- Acute Inflammatory Demyelinating Polyradiculoneuropathy, Stroke, Anosognosia, Central and Peripheral Neurodegenerative Pathologies
- Trial name
- NCT02722070
- Testing
- 3 Tesla Siemens Skyra MRI scanner
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Acute Ischemic Stroke
Ali Pay Intelligent Navigation Applet-aided Pre-hospital Triage for Non-emergency Medical Service Patients With Acute Ischemic Stroke
According to the Bigdata Observatory platform for Stroke of China (BOSC), the proportion of patients with acute ischemic stroke (AIS) receiving intravenous thrombolysis or endovascular treatment in China is 5.64% and 1.45%…
- Trial name
- i-Path (NCT06613074)
- Testing
- Ali Pay intelligent navigation applet
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Hemiparesis
Mechanisms of Arm Recovery in Stroke Patients With Hand Paralysis
This study examines the effect of non-invasive brain stimulation targeting different brain areas on movement of the affected arm post-stroke.
- Conditions
- Stroke, Hemiparesis, Cerebral Vascular Accident, Stroke, Ischemic
- Trial name
- NCT03067818
- Testing
- Unaffected Transcranial Magnetic Stimulation, Affected Transcranial Magnetic Stimulation, Control Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- George Mason University
Major Depressive Disorder
RESISTance Exercise for Depression Trial
Depression is a leading cause of disability worldwide and current treatments are ineffective for many people. This trial will investigate the efficacy of a 16-week high vs low dose resistance exercise training program for the…
- Trial name
- RESIST (NCT06110897)
- Testing
- High Dose Resistance Exercise Training, Low Dose Resistance Exercise Training Group
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of Wisconsin, Madison
Middle Cerebral Artery Aneurysm
Prospective, Multicenter Cohort Study on the Safety and Efficacy of Treatment for Middle Cerebral Artery Aneurysms
Intracranial aneurysm is one of the most common cerebrovascular diseases, with a prevalence of about 3.2%. With the aging of the population and the further popularization of MRA and other examination methods, the prevalence of…
- Trial name
- NCT04927520
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Ischemic Stroke
Multi-arm Optimization of Stroke Thrombolysis
The primary efficacy objective of the MOST trial is to determine if argatroban (100µg/kg bolus followed by 3µg/kg per minute for 12 hours) or eptifibatide (135µg/kg bolus followed by 0.75µg/kg/min infusion for two hours) results…
- Trial name
- MOST (NCT03735979)
- Testing
- Argatroban, Eptifibatide
- Where
- 61 sites in United States
- Volunteers
- 514 people
- Sponsor
- Washington University School of Medicine
Acquired Brain Injury, Stroke
Post-Brain Injury Walking and Balance Recovery Program
The purpose of this study is to test the efficacy of a walking and balance training program designed to safely challenge and improve walking performance and balance in relation to walking speed, strength, endurance, and balance…
- Conditions
- Acquired Brain Injury, Stroke, Traumatic Brain Injury
- Trial name
- NCT05934773
- Testing
- KineAssist robotic treadmill
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- The University of Texas Medical Branch, Galveston
CVA (Cerebrovascular Accident), Cerebral Hemorrhage
Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage
The purpose of the study is to determine whether lowering high blood pressure levels after the start of a stroke caused by bleeding in the brain (intracerebral haemorrhage) will reduce the chances of a person dying or surviving…
- Conditions
- CVA (Cerebrovascular Accident), Cerebral Hemorrhage, Intracranial Hemorrhages
- Trial name
- NCT00226096
- Testing
- Labetalol Hydrochloride, Metoprolol tartrate, Hydralazine Hydrochloride
- Where
- 20 sites in Australia, China and 1 more
- Volunteers
- 404 people
- Sponsor
- The George Institute
Stroke
Acute Stroke Advancing Program Using Telemedicine
The purpose is to evaluate the effectiveness and safety profile of telemedicine consultation system in making decision on IV thrombolysis.
- Trial name
- ASAP-Tel (NCT02088346)
- Testing
- Telemedicine consultation system
- Where
- 4 sites in China
- Volunteers
- 300 people
- Sponsor
- Xijing Hospital
Chronic Pain, Stroke
VR-ACT After Stroke: a Feasibility Study
This exploratory project aims to develop and pilot test, in a parallel group randomized controlled trial (RCT) design, the feasibility, acceptability, and preliminary efficacy of a self-management virtual reality (VR) 8-week…
- Trial name
- VR-ACT (NCT06990646)
- Testing
- VR-ACT
- Volunteers
- 30 people
- Sponsor
- University of Coimbra
Stroke, Aphasia
Recovery From Post-Stroke Aphasia With rTMS Targeting Left or Right Anterior Temporal Lobe
This project aims to tailor repetitive Transcranial Magnetic Stimulation (rTMS) target to the clinical profile of post-stroke aphasia, specifically focusing on lexicosemantic impairments, to enhance recovery.
- Trial name
- ATLAS (NCT07608588)
- Testing
- continuous Theta Burst Stimulation, intermittent Theta Burst Stimulation, Semantic Feature Analysis
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of South Carolina
Stroke, Hyperventilation Syndrome
Symptomatic Hyperventilation in Individuals Living With Stroke
This study will investigate the effects of hyperventilation syndrome on respiratory muscle strength, respiratory muscle endurance, pulmonary functions, and functional capacity in individuals living with stroke, and in this…
- Trial name
- NCT07840703
- Testing
- Respiratory Function, Respiratory Muscle Strength, and Functional Capacity Assessments
- Volunteers
- 92 people
- Sponsor
- Istinye University
Acute Ischemic Stroke, Biofeedback
Effects of Biofeedback in Patients With Acute Cerebral Infarction
The major aim of this study is to investigate the effects of biofeedback assisted abdominal breathing training on improving the psychological and physiological distress in patients with ACI.
- Conditions
- Acute Ischemic Stroke, Biofeedback, Autonomic Dysfunction, Cognitive Function, Psychological Distress
- Trial name
- NCT03516227
- Testing
- heart rate variability biofeedback
- Volunteers
- 40 people
- Sponsor
- National Defense Medical Center, Taiwan
Stroke
Fangshan / Family-based Ischemic Stroke Study In China
The exact etiology of ischemic stroke remains unclear, because multiple genetic predispositions and environmental risk factors may be involved, and their interactions dictate the complexity.
- Trial name
- FISSIC (NCT00534742)
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Peking University
Stroke, Ischemic
Rehabilitation Program Dedicated to Post-stroke Lateropulsion Including Exoskeleton Assisted Exercises
Lateropulsion is a deficit in the body orientation with respect to the vertical in the coronal plane, defined by the presence of one of the three signs: lateral body tilt, active pushing from the sound limbs, and resistance to…
- Trial name
- EXOLAT (NCT07023770)
- Testing
- specific lateropulsion rehabilitation program (exoskeleton + specific physiotherapy orientation rehabilitation), Conventional physiotherapy without without exercises dedicated to lateropulsion or verticality representation alleviation
- Where
- 2 sites in France
- Volunteers
- 3 people
- Sponsor
- University Hospital, Grenoble
Acute, Non-traumatic Subarachnoid Hemorrhage, Intraparenchymal Hemorrhage
Normoglycemia and Neurological Outcome
Brain injury patients who meet defined criteria will be assigned to intensive insulin treatment (target blood glucose levels of 10-110 mg/dl) or conventional IV insulin treatment (target glucose of 150-170 mg/dl).
- Conditions
- Acute, Non-traumatic Subarachnoid Hemorrhage, Intraparenchymal Hemorrhage, Brain Injuries
- Trial name
- NCT01137773
- Testing
- Insulin, Conventional insulin treatment
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Louisville
Alzheimer's Disease (Incl Subtypes), Depressive Symptoms
Beyond Listening: A Music-based Intervention
Study will be conducted to determine if caregivers who use music at home will feel less burden and whether the person they are caring for will demonstrate decreased symptoms of dementia.
- Trial name
- NCT04840173
- Testing
- Music
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- MJHS Institute for Innovation in Palliative Care
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