Clinical trials: Cerebrovascular Function
Stroke, Upper Extremity Paresis
Effects of Bihemispheric Transcranial Direct Current Stimulation on Motor Function in Stroke Patients
Motor impairment (impairment of movement) due to stroke is one of the leading disabilities in adults. In addition to established means of facilitating motor recovery after stroke such as physical and occupational therapy, a…
- Conditions
- Stroke, Upper Extremity Paresis, Transcranial Direct Current Stimulation
- Trial name
- NCT03839316
- Testing
- tDCS
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Baskent University
Ischemic Stroke, Intracranial Haemorrhage
Prospective, Randomized, Parallel-Controlled Study of Brain Computer Interface Integrated Robotic Mirror Therapy for Post-Stroke Upper Limb Motor Function Disorder
This study aims to utilize non-invasive brain-computer interface technology in conjunction with mirror therapy to design a new paradigm for rehabilitation robots to induce compensatory movements on the healthy side in stroke…
- Conditions
- Ischemic Stroke, Intracranial Haemorrhage, Brain-Computer Interfaces, Rehabilitation Exercise
- Trial name
- BCI-RMT (NCT07553416)
- Testing
- Brain computer interface-robotic mirror therapy
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Beijing Tiantan Hospital
Stroke, Post-Stroke Hemiparesis
Evaluation of a Wearable Exoskeleton for Functional Arm Training
The purpose of this study is to investigate how the cable-driven arm exoskeleton (CAREX) can assist task performance during 3D arm movement tasks under various experimental conditions in healthy individuals and patients with…
- Trial name
- NCT02726204
- Testing
- Gravity Elimination Alone, Path Assistance Alone, Path Assistance and Gravity Elimination
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Large Vessel Occlusion, Stroke
Head of Bed After Ischemic Stroke Thrombectomy (HoBIT)
Endovascular thrombectomy (EVT), also known as clot retrieval, is a procedure that improves recovery for people who suffer a stroke by removing blood clots from large blood vessels in the brain.
- Conditions
- Large Vessel Occlusion, Stroke, Ischemic Stroke
- Trial name
- HoBIT (NCT07367633)
- Testing
- Head of bed position of 0-degrees, Head of bed position of 30-degrees or greater
- Where
- 2 sites in Canada
- Volunteers
- 2,240 people
- Sponsor
- Population Health Research Institute
Stroke, Acute, Stroke (Subacute)
Inter-Limb Transfer in Acute Stroke
This study aims to investigate whether the improvements achieved through motor skill learning (MSkL) with the ipsilesional upper limb (UL) are transferred to the contralesional UL during the (sub)acute stroke phase, and to…
- Conditions
- Stroke, Acute, Stroke (Subacute), Healthy Individuals (Controls), Chronic Stroke Patients
- Trial name
- MLAS5 (NCT07822633)
- Testing
- REAplan®, Dextrain Manipulandum®
- Where
- 2 sites in Belgium
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University Hospital of Mont-Godinne
Stroke
Effect of Task Oriented Training on Cognitive Function in Elderly Stroke Patients
Background: The impact of stroke at the time of diagnosis is on the attention and executive functions, which may be impaired at various post-stroke intervals.
- Trial name
- NCT06445998
- Testing
- task oriented training
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Horus University
Stroke, Hemiparesis
CONSTRAINT-INDUCED MOVEMENT THERAPY (CIMT) VS. MIRROR THERAPY (MT) ON HAND FUNCTION AND SPASTICITY IN PATIENTS WITH HEMIPARESIS
This study aimed to compare the effects of Constraint-Induced Movement Therapy (CIMT) and Mirror Therapy (MT) on hand function and spasticity in individuals with hemiparesis.
- Conditions
- Stroke, Hemiparesis, Hemiparesis After Stroke
- Trial name
- NCT06910904
- Testing
- Constraint-Induced Movement Therapy (CIMT), Mirror Therapy (MT)
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- University of Lahore
Cerebrovascular Accident
Structural and Functional Brain Changes in Response to Post-Stroke Rehabilitation
The purpose of this research study is to improve methods for evaluation of brain changes during motor learning for patients with stroke, who have difficulty performing daily tasks with their arm and hand.
- Trial name
- NCT02351947
- Testing
- upper limb rehabilitation for chronic stroke
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Louis Stokes VA Medical Center
Stroke
Effects of Training Caregivers on the Outcomes of Stroke Survivors and Caregivers in Zimbabwe
The burden of stroke has continued to increase in Zimbabwe in the last 3 decades. resulting in increased burden of care to family caregivers.
- Trial name
- NCT02569099
- Testing
- Caregiver training
- Where
- Zimbabwe
- Volunteers
- 376 people
- Sponsor
- University of Zimbabwe
Stroke, Healthy
Use of Transcranial Direct Current Stimulation (tDCS) Coupled With Constraint Induced Movement Therapy in Stroke Patient
The purpose of this study is to determine whether noninvasive brain stimulation associated with motor learning offers an additional benefit than motor learning alone in patients with stroke.
- Trial name
- tdcs (NCT01143649)
- Testing
- transcranial direct current stimulation (tDCS), constraint induced movement therapy (CIMT), transcranial alternating current stimulation (tACS)
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Stroke, Arm Motor Recovery
Repetitive Arm Training + FES on Upper Extremity Motor Recovery in Sub-acute Stroke Survivors
Rehabilitation restores functions and reduces disabilities due to diseases sequelae. The relationship between intensity of rehabilitation and clinical outcomes, recently emphasized, has generated a great interest for…
- Trial name
- NCT02267798
- Testing
- conventional therapy, arm training combined with FES
- Where
- 2 sites in Italy
- Volunteers
- 64 people
- Sponsor
- University Hospital of Ferrara
Stroke
"Evaluation Of ALBA® Device for Upper Extremity Motor Function In Adults With Subacute And Chronic Acquired Brain Injury"
As part of the rehabilitation techniques, robotic equipment has been introduced for the rehabilitation of the upper extremity with promising results.
- Trial name
- NCT05824416
- Testing
- Experimental: ALBA, Conventional Therapy
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- uMov
Functional Independence, Respiratory Insufficiency
More Air - Better Performance - Faster Recovery
The objective of this study is to investigate i) the effect of 3 weeks IMT to adults post-stroke to maximal inspiratory pressure (MIP) and ii) the effects of 3 weeks IMT to the degree of dependency in activities of daily living…
- Trial name
- IMT (NCT04686019)
- Testing
- Inspiratory muscle training (IMT)
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Central Jutland Regional Hospital
Stroke
Neural Mobilization for Reduction of Spasticity in Stroke
Spasticity after stroke is common that affect upper limb strength and make activities of daily living difficult. There are many techniques but not any standardized technique for long term effect on reduction of spasticity and…
- Trial name
- NCT05314465
- Testing
- Median nerve mobilization
- Where
- 3 sites in India
- Volunteers
- 7 people
- Sponsor
- Asir John Samuel
Stroke
Tai Chi Training in Stroke Survivors
People with stroke suffer from different impairments, including the ability to dual-tasking, increased arterial stiffness, and dysfunction of the autonomic nervous system.
- Trial name
- NCT03252236
- Testing
- Tai Chi, Conventional exercise
- Where
- Hong Kong
- Volunteers
- 56 people
- Sponsor
- The Hong Kong Polytechnic University
Hypertension, Systolic, Cerebrovascular Disease
Intensive Versus Standard Blood Pressure Lowering to Prevent Functional Decline in Older People
This randomized clinical trial examines if lowering and maintaining 24-hour ambulatory systolic blood pressure to <130 mmHg (intensive control) versus <145 mmHg (standard control) slows/halts the progression of deterioration of…
- Trial name
- NCT01650402
- Testing
- Anti-hypertensive therapy to SBP 130 mm Hg, Anti-hypertensive therapy to SBP 145 mm Hg
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- UConn Health
Stroke, Stroke, Acute
The Effect of tDCS Combined With Functional Task Training on Motor Recovery in Stroke Patients
We propose to enhance the effects of brain plasticity using a powerful noninvasive technique for brain modulation consisting of navigated transcranial magnetic stimulation (TMS) priming with transcranial direct current…
- Conditions
- Stroke, Stroke, Acute, Motor Function
- Trial name
- NCT04646577
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct Current Stimulation (tDCS
- Volunteers
- 40 people
- Sponsor
- King Fahad Specialist Hospital Dammam
Stroke, Cerebrovascular Accident (CVA)
Transcutaneous Vagus Nerve Stimulation (tVNS) and Robotic Training to Improve Arm Function After Stroke
The purpose of this study is to evaluate if multiple therapy sessions of Transcutaneous Vagus Nerve Stimulation (tVNS) combined with robotic arm therapy lead to a greater functional recovery in upper limb mobility after stroke…
- Conditions
- Stroke, Cerebrovascular Accident (CVA), Hemiparesis
- Trial name
- tVNS (NCT03592745)
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Northwell Health
Aging, Arterial Stiffness
Inorganic Nitrate Supplementation on Cerebrovascular Aging and Arterial Stiffness Study
This study investigates the effect of dietary inorganic nitrate supplementation on 1) large elastic artery stiffness and hemodynamics and 2) cerebrovascular function in middle-aged and older adults.
- Conditions
- Aging, Arterial Stiffness, Endothelial Dysfunction, Hypertension
- Trial name
- INCA (NCT03617302)
- Testing
- Experimental: Nitrate-containing
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gary L. Pierce, PhD
Stroke
A Study on Brain Activity During Transcranial Direct Current Stimulation in Stroke Patients
The purpose of this study is to identify the characteristics of neural plasticity seen in stroke patients by measuring the changes in brain activity during stimulation using functional near-infrared spectroscopy (fNIRS) when…
- Trial name
- NCT04549753
- Testing
- Transcranial direct current simulation
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center