Clinical trials: Cervical Abnormalities
Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor
Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas
This phase I trial is studying the side effects and best dose of oxaliplatin when given together with irinotecan in treating young patients with refractory solid tumors or lymphomas.
- Conditions
- Childhood Burkitt Lymphoma, Childhood Central Nervous System Germ Cell Tumor, Childhood Diffuse Large Cell Lymphoma, Childhood Grade III Lymphomatoid Granulomatosis
- Trial name
- NCT00101270
- Testing
- irinotecan hydrochloride, oxaliplatin
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Cancer Institute (NCI)
Atlantoaxial Dislocation, Chiari Malformation
Clinical Study of the Treatment of Chiari Malformation Combined With Type II Skull Base Depression
The research background of this study is that Chiari malformation (CM) is a congenital malformation in the foramen magnum region, often associated with syringomyelia, basilar depression, odontoid dislocation and other…
- Conditions
- Atlantoaxial Dislocation, Chiari Malformation, Basilar Invagination
- Trial name
- NCT05754554
- Testing
- Atlas occipital decompression lateral joint release combined with occipital-neck fusion, Simple FMD with Outer Dural Delamination
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Southern Medical University, China
Velopharyngeal Insufficiency, Head and Neck Cancer
Velopharyngeal Dysfunction in Head & Neck Cancer Patients, Pilot Study
Some head and neck cancer survivors develop velopharyngeal dysfunction (VPD), a problem with closure between the soft palate and throat that can cause nasal-sounding speech, food or liquid leaking into the nose, difficulty…
- Conditions
- Velopharyngeal Insufficiency, Head and Neck Cancer, Survivorship, Dysphagia
- Trial name
- NCT07264036
- Testing
- Pharyngeal Wall Augmentation Injection
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanessa Torrecillas
Triple-negative Breast Cancer, NSCLC, Squamous or Non-Squamous
AN0025 and Pembrolizumab Combination in Advanced Solid Tumors
This is an open-label, multicenter, phase Ib study to evaluate the safety and preliminary efficacy of AN0025 in combination with pembrolizumab in patients with locally advanced/metastatic tumors.
- Conditions
- Triple-negative Breast Cancer, NSCLC, Squamous or Non-Squamous, Urothelial Carcinoma of the Bladder, Microsatellite Stable (MSS) Colorectal Cancer (CRC)
- Trial name
- NCT04432857
- Testing
- AN0025, Pembrolizumab
- Where
- 6 sites in United States, France
- Volunteers
- 63 people
- Sponsor
- Adlai Nortye Biopharma Co., Ltd.
Head and Neck Neoplasm, Cleft Palate
Characteristics of a Maxillofacial Prosthesis Consultation Within Assistance Publique - Hopitaux de Paris
Patients treated with Maxillofacial Prosthesis have loss of maxillary and/or mandibular substances. Few data are available on quality of life of these patients and its association with some of their socio-demographic, medical and…
- Conditions
- Head and Neck Neoplasm, Cleft Palate, Cleft Lip
- Trial name
- PEC-PMF (NCT04277273)
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neurologic Disorder, Paralysis
COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis
The Synchron motor neuroprosthesis (MNP) is intended to be used in subjects with severe motor impairment, unresponsive to medical or rehabilitative therapy and a persistent functioning motor cortex.
- Conditions
- Neurologic Disorder, Paralysis, Paralysis; Stroke, Amyotrophic Lateral Sclerosis
- Trial name
- NCT05035823
- Testing
- Motor Neuroprosthesis (MNP)
- Where
- 3 sites in United States
- Volunteers
- 6 people
- Sponsor
- Synchron Medical, Inc.
Hypospadias
The Change of the Detrusor Thickness After Hypospadias Repair - Comparison With the Normal Control Group
Even successfully managed hypospadias without any complication, voiding problem could be developed due to the increased urethral resistance.
- Trial name
- NCT01762007
- Where
- South Korea
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yonsei University