Clinical trials: Cervical Dilation
Abortion Late, Pain
Paracervical Block for Pain Control With Osmotic Dilator Placement
Cervical dilators are frequently used for preparation prior to second trimester surgical abortion. While their use decreases complications associated with surgical abortion, their placement is often uncomfortable for the patient.
- Trial name
- NCT02354092
- Testing
- Local anesthetic for tenaculum placement, Paracervical Block, Dilator Placement
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Induced Abortion, Abortion Techniques
Mifepristone Versus Misoprostol for Cervical Preparation Prior to Surgical Abortion Between 11 to 15 Weeks
Surgical abortion in the late first trimester and early second trimester is usually performed with the aid of a cervical preparing agent, which helps to open up the uterine cervix for the procedure.
- Conditions
- Induced Abortion, Abortion Techniques, Mifepristone, Misoprostol
- Trial name
- MIMI11-15 (NCT01636063)
- Testing
- Mifepristone, Misoprostol
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Boston University
Second Trimester Abortion
Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation
Primary objective: To study the difference in dilation and evacuation (D\&E) procedure time following overnight cervical preparation with laminaria or Dilapan-S™.
- Trial name
- NCT02033083
- Testing
- Laminaria, Dilapan-S
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Cervix; Pregnancy
Sound Check-Correlation Between Transperineal and Digital Cervical Exam in 3rd Trimester Pregnancy
The primary purpose of this study is to compare the accuracy of the Butterfly iQ pocket ultrasound with the digital cervical examination in the third trimester cervix.
- Trial name
- NCT05260333
- Testing
- Butterfly iQ transperineal ultrasound exam
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Contraception
Misoprostol With Intrauterine Device Insertion
The purpose of this study is to see if using misoprostol (a medication that softens the cervix) before placing an intrauterine device for contraception reduces pain in women who have never delivered a baby.
- Trial name
- NCT00613366
- Testing
- Misoprostol, Magnesium Oxide
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Abortion, Second Trimester
24-hour Mifepristone and Buccal Versus Mifepristone and Vaginal Misoprostol for Cervical Preparation for D&E
This study aims to compare mifepristone and buccal misoprostol to mifepristone and vaginal misoprostol for cervical preparation for second trimester dilation and evacuation (D\&E).
- Trial name
- NCT03134183
- Testing
- Vaginal Misoprostol, Buccal Misoprostol
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Pain Management, Cervical Preparation
Self-administered Lidocaine Gel for Pain-control During Cervical Preparation for Dilation and Evacuation
This study seeks to compare self-administered lidocaine gel for pain control during cervical preparation for dilation and evacuation (D\&E) to paracervical block.
- Trial name
- NCT02852434
- Testing
- Lidocaine Gel (2%), Lidocaine Paracervical Block (1%)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pain Management
Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Control During Cervical Dilator Placement Prior to Dilation and Evacuation
This study evaluates the use of Transcutaneous Electrical Nerve Stimulation (TENS) as a method of pain control during osmotic dilator insertion prior to dilation and evacuation.
- Trial name
- NCT03868787
- Testing
- TENS
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Ashley Turner, MD
Abortion, Induced
Cervical Preparation Before Dilation and Evacuation
The purpose of this research study is to compare three different ways of opening a woman's cervix before her second-trimester surgical abortion.
- Trial name
- NCT01751087
- Testing
- Mifepristone, misoprostol, Osmotic dilators
- Where
- 7 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood League of Massachusetts
Pain
12 Versus 20 mL PCB for D&E Cervical Prep
More research is needed to investigate methods of pain control for cervical preparation for abortion procedures. Women report pain with paracervical block injection as well as with osmotic dilator placement.
- Trial name
- NCT03356145
- Testing
- 12 mL paracervical block, 20 mL paracervical block
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Stanford University