Clinical trials: Cervical Dilation
Superficial Injuries Involving Head With Neck
The Relationship Between Isolated Head Trauma During Pregnancy and Preterm Birth
Pregnant patients who presented to the Emergency Department of Şanlıurfa Training and Research Hospital with isolated head trauma due between January 2018 and January 2024 were included in the study and followed up with until the…
- Trial name
- PB (NCT06685549)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sanliurfa Education and Research Hospital
Abortion, Induced
Value of Mifepristone in Cervical Preparation Prior to Dilation and Evacuation 19-24 Weeks
A common practice for preparation for surgical abortion after 19 weeks gestation is the placement of multiple sets of osmostic dilators 1-2 days prior to the procedure.
- Trial name
- NCT01615731
- Testing
- Mifepristone, Hygroscopic cervical dilators, Misoprostol
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Cervix; Pregnancy
Comparative Study Between Only Vaginal Misoprostol and Vaginal Misoprostol and Estradiol Cream
To compare the safety and effectiveness of vaginal misoprostol with combined vaginal misoprostol and estradiol for induction of labour in unfavorable cervix
- Trial name
- NCT05306405
- Testing
- Vaginal Tablet
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Second Trimester Abortion
Laminaria Compared to Dilapan-S for Cervical Preparation Before Dilation and Evacuation at 18-24 Weeks of Gestation
Primary objective: To study the difference in dilation and evacuation (D\&E) procedure time following overnight cervical preparation with laminaria or Dilapan-S™.
- Trial name
- NCT02033083
- Testing
- Laminaria, Dilapan-S
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Cervix Uteri Dilation
Effectiveness and Safety Evaluation of Aqueduct -100 Device
Evaluation of efficacy and safety of using Aqueduct -100 - Cervical Dilator Device
- Trial name
- NCT02941211
- Testing
- Aqueduct -100
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aqueduct Medical Ltd
Labor; Poor, Primary
Mixed Reality Training for Teaching Cervical Effacement and Dilation
The aim of this educational research is to determine whether a mixed reality-based training program is effective in teaching midwifery students how to assess cervical effacement and dilation.
- Trial name
- NCT07238205
- Testing
- mixed reality education, Standard Education Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mardin Artuklu University
Abortion Late, Pain
Paracervical Block for Pain Control With Osmotic Dilator Placement
Cervical dilators are frequently used for preparation prior to second trimester surgical abortion. While their use decreases complications associated with surgical abortion, their placement is often uncomfortable for the patient.
- Trial name
- NCT02354092
- Testing
- Local anesthetic for tenaculum placement, Paracervical Block, Dilator Placement
- Where
- 2 sites in United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Labor Complication, Cervix; Open
4 Versus 6 cm Active Phase of Labour
A study to compare maternal and perinatal outcome between 4 and 6 cm cervical dilatation at amniotomy.
- Trial name
- NCT05339399
- Testing
- oxytocin augmentation
- Where
- Malaysia
- Volunteers
- 155 people
- Sponsor
- National University of Malaysia
Abortion, Second Trimester, Abortion, Medical
Foley Balloon for Cervical Preparation Before Dilation and Evacuation
To evaluate the Foley Balloon technique for cervical preparation before second trimester surgical abortion between 16 and 21 weeks estimated gestational age in combination with misoprostol to prepare the cervix before dilation…
- Trial name
- NCT06850974
- Testing
- Foley Balloon Catheter, Misoprostol, Laminaria
- Where
- Mozambique
- Volunteers
- 102 people
- Sponsor
- Stony Brook University
Cervical Dilatation, Bishop Score
the Effects of Epidural Fentanyl on Vaginal Delivery
The study hypothesis was that epidural fentanyl may accelerate the dilation of the cervix and possibly result in a shorter duration of vaginal delivery.
- Conditions
- Cervical Dilatation, Bishop Score, Duration of Delivery
- Trial name
- EFVD (NCT02135224)
- Testing
- Fentanyl, Normal saline
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Athens
Cervical Dilation
Self-Obtained Ultrasound Scans for Measurement of Cervical Dilation and Effacement in Labor
This is a pilot study to test the accuracy and comfort of self-directed ultrasound imaging of cervical dilation and effacement in pregnant women undergoing induction of labor.
- Trial name
- NCT05038891
- Testing
- Digital Cervical Exam, Transperineal Ultrasound, Transvaginal Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Induction of Labor Affected Fetus / Newborn
Dilapan-S® for Induction of Labor The Feasibility Study
This is a prospective feasibility study to investigate Dilapan-S® as an outpatient method of cervical ripening in low risk pregnancies >=39 weeks.
- Trial name
- DILATE (NCT04521062)
- Testing
- Dilapan S
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Cervical Cancer, Endometrial Cancer
Compliance to Vaginal Dilation Therapy in Patients Who Have Undergone Radiation Therapy For Stage IB, Stage IIA, Stage IIB, Stage IIIA, or Stage IIIB Cervical Cancer or Stage IA, Stage IB, Stage IIA, or Stage IIB Endometrial Cancer
RATIONALE: Understanding how well patients comply with their treatment regimen may help doctors determine best treatment and ongoing care for future patients.
- Conditions
- Cervical Cancer, Endometrial Cancer, Radiation Toxicity, Sexuality and Reproductive Issues
- Trial name
- NCT00735514
- Testing
- compliance monitoring, questionnaire administration, assessment of therapy complications
- Where
- 8 sites in United States
- Volunteers
- 83 people
- Sponsor
- Case Comprehensive Cancer Center
Hysteroscopic Surgery, Pain, Postoperative
A Trial for Peroperative Procedure and Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine Administration
Dilatation of the cervix is necessary before operative hysteroscopic procedures. This dilatation with Hegar dilators has certain difficulties and is associated with pain.
- Trial name
- NCT03359655
- Testing
- Misoprostol, Hyoscine butyl bromide
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Abortion
Mifepristone Versus Laminaria Insertion for Cervical Preparation Prior to Surgical Abortion at 14-16 Weeks
Women who are requesting pregnancy termination at 14-16 weeks, who would normally have osmotic dilator insertion the day before their procedure, would be asked if they wanted to participate.
- Trial name
- SAMi (NCT00986921)
- Testing
- mifepristone 200 mg, osmotic dilator insertion
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Twin Pregnancy, Antepartum Condition or Complication, Preterm Birth
Physical Exam Indicated Cerclage in Twin Gestations
This is a multicenter randomized study designed to determine if physical exam indicated cerclage reduces the incidence of spontaneous preterm birth <34 weeks in asymptomatic women with twin gestations and dilated cervix…
- Conditions
- Twin Pregnancy, Antepartum Condition or Complication, Preterm Birth, Cervical Dilation Premature
- Trial name
- TWIN-PEIC (NCT02490384)
- Testing
- Physical exam indicated cerclage
- Where
- 11 sites in United States, Italy and 1 more
- Volunteers
- 30 people
- Sponsor
- Thomas Jefferson University
Pregnancy, No Pregnancy Complications
Effect of Maryam Plant and Surah on Birth Pain, Anxiety and Satisfaction
This randomized controlled trial was conducted to determine the effects of spiritual support provided by Virgin Mary's hand plant and Surah Maryam on labor anxiety, labor pain, and satisfaction.
- Conditions
- Pregnancy, No Pregnancy Complications, Cervical Dilatation of 4-6 cm (Early Active Phase), Muslim
- Trial name
- NCT07175337
- Testing
- Surah Maryam group, Virgin Mary's Hand Plant Group
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Procedural Pain, Buprenorphine
Addition of Buprenorphine to Paracervical Block for Pain Control During Osmotic Dilator Insertion
Cervical preparation with osmotic dilators is commonly used prior to dilation and evacuation (D\&E) procedures to decrease the risk of complications.
- Conditions
- Procedural Pain, Buprenorphine, Adjuvants, Anesthesia, Dilation and Evacuation
- Trial name
- ABCD&E (NCT04254081)
- Testing
- Buprenorphine 0.15 MG, Lidocaine 1% Injectable Solution
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of California, San Diego
Preterm Birth, Obstetric Labor, Premature
Azithromycin to Improve Latency in Exam Indicated Cerclage Control Trial
Azithromycin is an antibiotic that is effective against bacteria that been associated with preterm birth (PTB). The purpose of this study is to evaluate if the addition of azithromycin prior to exam indicated cerclage prolongs…
- Conditions
- Preterm Birth, Obstetric Labor, Premature, Obstetric Labor Complications, Pregnancy Complications
- Trial name
- ALEC (NCT05132829)
- Testing
- Azithromycin 1 gram IV, Cefazolin and indomethacin
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Cervical Cancer
Effect of Bladder Distension on Dosimetry in Brachytherapy of Cervical Cancer
The purpose of this study is to compare, for each patient, dosimetry of organs at risk (bladder, rectum, sigmoid, small bowel) in two bladder distension procedures (emptied by a urinary catheter or filled with 120cc) during PDR…
- Trial name
- VESICOL (NCT02865837)
- Testing
- brachytherapy
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Institut de Cancérologie de Lorraine