Clinical trials: Cervical Disc Disease
Cervical Spine Disc Disease, Surgery
ACDF Comparison Trial
This research protocol seeks to compare radiological and clinical outcomes of cervical spine disease patients following standard-of-care anterior cervical discectomy and fusion (ACDF) using allograft fusion versus Cohere porous…
- Conditions
- Cervical Spine Disc Disease, Surgery, Fusion of Spine, Degenerative Disc Disease
- Trial name
- NCT03187171
- Testing
- Allograft Fusion, Cohere PEEK Fusion Group
- Sponsor
- Duke University
Clinical Radiculopathy, Myelopathy Due to a Cervical Disk Disease
Arthroplasty Versus Fusion in Anterior Cervical Surgery: Prospective Study of the Impact on the Adjacent Level
The aim of the study is to evaluate the impact of the cervical disk surgery on the deterioration of the adjacent levels. The investigators compare the radiological deterioration of adjacent levels, at 3 years, in both situation…
- Trial name
- PROCERV (NCT00554528)
- Testing
- cervical disc prosthesis with a mobile insert named Mobi-C, arthrodesis - cervical disk surgery
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Cervical Spondylosis
Effectiveness and Safety of Mobile Artificial Cervical Vertebrae Replacement for Patients With Cervical Spondylosis
The research team designed an artificial cervical joint prosthesis suitable for subtotal resection of the lower cervical vertebral body.
- Trial name
- NCT04813211
- Testing
- mobile artificial cervical vertebrae replacement, anterior cervical corpectomy and fusion
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xi'an International Medical Center Hospital
Spondylosis, Cervical Spondylosis
ViBone in Cervical and Lumbar Spine Fusion
Assess clinical and radiographic outcomes in patients who undergo 1-3 level anterior cervical discectomy fusion (ACDF) or lumbar interbody fusion (TLIF, PLIF, ALIF, or LLIF) using ViBone.
- Conditions
- Spondylosis, Cervical Spondylosis, Spondylolisthesis, Herniated Nucleus Pulposus
- Trial name
- NCT03425682
- Testing
- ViBone
- Where
- 4 sites in United States
- Volunteers
- 118 people
- Sponsor
- Elutia Inc.
Degenerative Disc Disease, Disc Herniation
Adjacent Level Anterior Cervical Fusion: SeaSpine Shoreline Versus Removal of Previously Implanted Plate and Replating
The purpose of this study is to evaluate the efficacy of SeaSpine Shoreline device in surgery of the cervical spine.
- Trial name
- NCT06415136
- Testing
- SeaSpine Shoreline
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Research Source
Symptomatic Cervical Disc Disease
Safety and Efficacy Study Comparing ProDisc-C to ACDF Surgery to Treat SCDD
The objective of this clinical investigation is to compare the safety and effectiveness of ProDisc-C to anterior cervical discectomy and fusion (ACDF) surgery in the treatment of symptomatic cervical disc disease (SCDD).
- Trial name
- NCT00291018
- Testing
- Total Disc Replacement, ACDF
- Volunteers
- 368 people
- Sponsor
- Synthes USA HQ, Inc.
Cervical Degenerative Disc Disease, Radiculopathy
An Investigation of the Metal Concentration in Patients Implanted With the PRESTIGE LP™ Cervical Disc at Two Contiguous Levels in the Cervical Spine
This clinical study will assess the metal concentrations present in the blood serum of patients who receive surgical treatment with the PRESTIGE LP™ Cervical Disc at two contiguous cervical levels from C3-C7.
- Conditions
- Cervical Degenerative Disc Disease, Radiculopathy, Myelopathy
- Trial name
- NCT03062657
- Testing
- PRESTIGE LP™ Cervical Disc
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- Medtronic Spinal and Biologics
Degenerative Disc Disease, Degenerative Spondylolisthesis
Natural Matrix Protein™ (NMP™) Fibers in Cervical and Lumbar Interbody Fusion
The aim of this study is to evaluate the effectiveness and safety of Natural Matrix Protein™ (NMP™) fibers when used in cervical or lumbar interbody fusion in patients with degenerative disc disease (DDD), spinal stenosis…
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT06000319
- Testing
- Natural Matrix Protein (NMP) Fibers, Lumbar interbody fusion, Cervical interbody fusion
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Induce Biologics USA Inc.
Intervertebral Disc Displacement, Neck Pain
Effects of IASTM and Vibration Therapy in Cervical Disc Herniation
This study investigates the effects of instrument-assisted soft tissue mobilization (IASTM) and percussion massage therapy on pain, functional status, proprioception, and kinesiophobia in individuals with cervical disc…
- Trial name
- NCT06903000
- Testing
- a percussion massage gun, specially designed stainless-steel instruments, Conventional Exercise Group (Control)
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Emre DANSUK
Spinal Pathologies, Pain
Patient Reported Outcome Measurements Registration in Spinal Pathologies and Neuromodulation
Longitudinal prospective observational data collection with questionnaires and categorical diagnostic and therapeutic registration and follow-up in spinal pathologies and neuromodulation
- Conditions
- Spinal Pathologies, Pain, Cervical Pain, Lumbar Pain Syndrome
- Trial name
- PROMSPINE (NCT07552519)
- Where
- Belgium
- Volunteers
- 5,000 people
- Sponsor
- Jessa Hospital
Cervical Disc Herniation
The Effect of Tendon Release Techniques in Patients With Cervical Disc Herniation
The goal of this clinical trial is to investigate the effect of using enhanced golgi tendon organ stimulation on symptoms in patients with cervical disc herniation.
- Trial name
- NCT06526325
- Testing
- Enhanced golgi tendon organ stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Istanbul Arel University
Degenerative Disc Disease (DDD), Instabilities
PMCF Study to Evaluate the VERTICALE® Cervical System in Spine Surgery According to Its Intended Use.
In accordance with the European Medical Device Regulation MDR 2017/745/EU, the legal manufacturers of medical devices are obliged to evaluate medical devices with regard to their clinical performance and safety.
- Conditions
- Degenerative Disc Disease (DDD), Instabilities, Trauma, Deformity
- Trial name
- NCT05489822
- Testing
- VERTICALE® Cervical System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Silony Medical GmbH
Symptomatic Cervical Disc Disease
Performance of the Hedrocel(R) Cervical Fusion Device
The objective of this clinical investigation is to compare patients treated with Anterior Cervical Discectomy and Fusion (ACDF) using the Hedrocel Cervical Fusion Device, with a concurrent, randomized, control group receiving…
- Trial name
- NCT00758758
- Testing
- Anterior Cervical Discectomy and Fusion
- Where
- 13 sites in United States
- Volunteers
- 231 people
- Sponsor
- Zimmer Biomet
Cervical Radiculopathy, Cervical Radicular Pain
Effect of Myofascial Release Technique in Patients with Unilateral Cervical Radiculopathy
The aim of the study is to investigate the effectiveness of myofascial release technique on pain, range of motion, muscle strength, functionality and quality of life in individuals diagnosed with cervical radiculopathy with…
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Cervical; Hernia, Cervical Disc Disease
- Trial name
- NCT04597112
- Testing
- Myofascial Release Technique, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Cervical Spondylosis, Cervical Radiculopathy
Evaluation of DTRAX Graft in Patients With Cervical Degenerative Disc Disease
DTRAX Graft is used to relieve nerve pressure in the neck in order to provide relief for Cervical Degenerative Disc Disease. This study is being conducted to determine the effectiveness of the graft, and to find out whether or…
- Conditions
- Cervical Spondylosis, Cervical Radiculopathy, Cervical Degenerative Disc Disease
- Trial name
- NCT01616719
- Testing
- DTRAX Graft
- Where
- 2 sites in United States
- Sponsor
- Providence Medical Technology, Inc.
Image, Body, Neck Pain
Investigation of the Effect of Motor Imagery Training in Individuals With Cervical Discogenic Pain
In this study, motor control exercises including cervical region, upper extremity and scapular region muscles will be applied routinely in individuals with chronic neck pain.
- Conditions
- Image, Body, Neck Pain, Disc Herniation
- Trial name
- NCT05999565
- Testing
- Motor Imagery Exercises, Motor Control Exercises
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hacettepe University
Degenerative Disc Disease
Cervical Interbody Fusion Device Patient Registry
The registry has been designed as a prospective, observational program for patients undergoing anterior cervical discectomy and fusion (ACDF) procedures treated with TIDAL cervical interbody fusion device.
- Trial name
- NCT05114356
- Testing
- TIDAL Cervical Interbody Fusion implant
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Restor3D
Intervertebral Disc Degeneration
Safety and Performance of the SPINEVISION Hexanium ACIF in the Treatment of Cervical Spine Degenerative Disc Disease
The goal of this observational study is to confirm the safety and efficacy of the Hexanium ACIF system in the treatment of skeletally mature patients suffering from degenerative disc disease (disease that occurs when the spinal…
- Trial name
- NCT06155409
- Testing
- Anterior cervical interbody fusion
- Where
- 6 sites in France
- Volunteers
- 148 people
- Sponsor
- SPINEVISION SAS
Cervical Disc Herniation
Muscular Endurance And Its Association With Neck Pain, Disability, Neck Awareness, And Kinesiophobia
The aim of this study was to investigate the relationship of muscular endurance of the trunk, upper extremities, and scapular region as well as cervical region, with pain, neck awareness, and kinesiophobia in patients with…
- Trial name
- NCT05121467
- Testing
- Pain Assessment, Assessment of Muscular Endurance, Assessment of Neck Awareness
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Spondylosis, Spinal Stenosis
A Prospective Study of NuCel® in Cervical Spine Fusion
The study is intended to demonstrate that the NuCel® allograft is effective and safe in promoting bone growth and fusion rate when used in cervical fusion in patients with one, two or three-level diseases of the cervical spine.
- Conditions
- Spondylosis, Spinal Stenosis, Spondylolisthesis, Intervertebral Disc Disease
- Trial name
- NCT02381067
- Testing
- NuCel with Allograft Bone
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- NuTech Medical, Inc