Clinical trials: Cervical Disk Disease
Cervical Radiculopathy, Proprioception
Assessment of Upper Extremity Proprioception in Patients With Cervical Radiculopathy
There is no study in the current literature that systematically investigates the extent of upper-extremity proprioceptive impairment in patients with radicular neuropathic symptoms secondary to cervical disc herniation, nor its…
- Conditions
- Cervical Radiculopathy, Proprioception, Cervical Disc Herniation, Proprioception Reaching Test
- Trial name
- NCT07319156
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Marmara University
Intervertebral Disc Disease, Spondylolisthesis
PASS OCT® Post-market Clinical Follow-up
Prospective, multicenter non comparative and observational study (post-market clinical follow-up). Patients operated with PASS OCT® manufactured by MEDICREA® INTERNATIONAL between July 2016 and July 2017.
- Conditions
- Intervertebral Disc Disease, Spondylolisthesis, Spinal Stenosis, Spinal Neoplasms
- Trial name
- NCT02931279
- Testing
- PASS OCT® Spinal System
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Medicrea International
Herniated Intervertebral Disc
Artificial Intelligence Assisted Spine Rehabilitation in Cervical Disc Herniation
The aim of this study is to investigate the effect of artificial intelligence-assisted spinal rehabilitation in neck hernia compared to traditional methods.
- Trial name
- NCT06632028
- Testing
- artificial intelligence assisted spinal rehabilitation, conventional therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Okan University
Cervical Disc Disease, Cervical Spine Disease
Analysis of Cervical Spinal MRI With Deep Learning
The aim of this study is analyzing the pathologies in cervical spinal MRI images by using image processing algorithms. Determination of these pathological cases which taught to the system with deep learning and determination of…
- Trial name
- NCT04239638
- Testing
- Cervical Spinal MRI
- Where
- Turkey (Türkiye)
- Sponsor
- Bezmialem Vakif University
Cervical Radiculopathy, Cervical Radicular Pain
Effect of Myofascial Release Technique in Patients with Unilateral Cervical Radiculopathy
The aim of the study is to investigate the effectiveness of myofascial release technique on pain, range of motion, muscle strength, functionality and quality of life in individuals diagnosed with cervical radiculopathy with…
- Conditions
- Cervical Radiculopathy, Cervical Radicular Pain, Cervical; Hernia, Cervical Disc Disease
- Trial name
- NCT04597112
- Testing
- Myofascial Release Technique, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Cervical Disc Disease
A Clinical Trial Evaluating a Total Disc Replacement in Patients With Cervical Disc Disease
This study will be a non-randomized trial consisting of patients with single level (C3 to C7) symptomatic cervical disc disease who have not previously received fusion surgery at the same level, and have failed to improve with…
- Trial name
- CerPass (NCT01433367)
- Testing
- CerPass® Total Disc Replacement
- Where
- Mexico
- Volunteers
- 2 people
- Sponsor
- NuVasive
Cervical Radiculopathy, Cervical Disc Disease
Prospective Study of Fusion Rates Using Spira-C Device for Anterior Cervical Discectomy and Fusion Surgery
The objective of this study is to perform a prospective, single-arm clinical evaluation utilizing the Spira™-C 3-D printed titanium interbody device for treatment of degenerative disc disease and spinal stenosis of the cervical…
- Trial name
- ACDF (NCT03786432)
- Testing
- Spira-C Interbody Device
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Corewell Health East
Degenerative Disc Disease
Evaluation of Safety and Effectiveness of Primary Hybrid Construct of Mobi-C and ACDF in the Treatment of Two-level Symptomatic Degenerative Disc Disease in the Cervical Spine.
The study is a prospective, multi-center cohort study of patients with two-level DDD implanted with CDA adjacent to ACDF (hybrid construct).
- Trial name
- NCT06485206
- Testing
- One level Mobi-C and one level fusion
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Highridge Medical
Cervical Spondylosis
Prognostic Factors for ACDF With BAK/C in Cervical Disc Disease
This retrospective study aimed to identify predictive prognostic factors for treatment outcomes in patients with cervical degenerative disc disease (CDDD).
- Trial name
- NCT07069114
- Testing
- Anterior Cervical Discectomy and Fusion with BAK/C Interbody Fusion
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Liang Hao
Radiculopathy, Myelopathy
PCM Cervical Disc System
The PCM Cervical Disc was studied in a prospective, multicenter, randomized FDA-approved investigational device exemption (IDE) clinical trial conducted in the United States to evaluate longitudinal outcomes over 2 years…
- Trial name
- NCT00578812
- Testing
- Anterior Cervical Discectomy and Fusion (ACDF), PCM Cervical Disc
- Where
- 23 sites in United States
- Volunteers
- 494 people
- Sponsor
- NuVasive
Spondylosis, Spinal Stenosis
A Prospective Study of NuCel® in Cervical Spine Fusion
The study is intended to demonstrate that the NuCel® allograft is effective and safe in promoting bone growth and fusion rate when used in cervical fusion in patients with one, two or three-level diseases of the cervical spine.
- Conditions
- Spondylosis, Spinal Stenosis, Spondylolisthesis, Intervertebral Disc Disease
- Trial name
- NCT02381067
- Testing
- NuCel with Allograft Bone
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- NuTech Medical, Inc
Degenerative Disc Disease, Trauma (Including Fractures)
BIO4 Clinical Case Study: Cervical Spine
The goal of this study is to investigate the efficacy of BIO4 bone matrix in patients undergoing 1 or 2-level Anterior Cervical Discectomy and Fusion (ACDF) spine surgery.
- Conditions
- Degenerative Disc Disease, Trauma (Including Fractures), Spondylolisthesis
- Trial name
- NCT03077204
- Testing
- 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seton Healthcare Family
Cervical Radiculopathy
Treatment of One and/or Two Level Cervical Degenerative Disc Disease
The objective of this study is to collect clinical and radiographic outcomes using the CONDUIT™ Interbody Cervical System with supplemental fixation using a DePuy Synthes Cervical Plating System.
- Trial name
- NCT05812092
- Testing
- CONDUIT Interbody Cervical System with DePuy Synthes Cervical Plating System
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Research Source
Cervical Disc Degeneration
Compare Different Cervical Anterior Discectomy Procedures by After Procedure Sagittal Alignment on Radiograph
Patients with single-level cervical degenerative disc disease commonly undertook anterior discectomy. To compare the effect of anterior cervical discectomy without fusion (ACD), anterior cervical discectomy with fusion by…
- Trial name
- NCT03360409
- Testing
- ACD, ACDF, ACDA
- Volunteers
- 150 people
- Sponsor
- Peking University People's Hospital
Neck Pain, Musculoskeletal Diseases
Efficacy of Pulse Electromagnetic Field Therapy (PEMF) in Patients With Nonspecific Chronic Neck Pain
This investigation aims to investigate the effectiveness of Pulse Electromagnetic Field Therapy (PEMF) on neck pain, cervical range of motion, pressure pain threshold and quality of life in patients with nonspecific chronic neck…
- Conditions
- Neck Pain, Musculoskeletal Diseases, Chronic Neck Pain, Cervical Disc Disease
- Trial name
- NCT05581186
- Testing
- Pulse electromagnetic field therapy, Therapeutic Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Afyonkarahisar Health Sciences University
Cervical Degenerative Disc Disease
Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study)
This study is intended to treat patients with symptomatic degenerative disc disease at one level of the cervical spine. The patients will be randomized to the DISCOVER Artificial Cervical Disc (total disc replacement) or…
- Trial name
- NCT00432159
- Testing
- Cervical TDR, ACDF with plate
- Where
- 32 sites in United States, Australia and 1 more
- Volunteers
- 500 people
- Sponsor
- DePuy Spine
Cervical Radiculopathy, Cervical Spondylosis
Effectiveness of Cervical Transforaminal Epidural Steroid Injection
Study Purpose: This study is intended to monitor outcomes for 1 year following cervical TFESI. Based on current clinic volume and enrollment rates into a current study of cervical epidural injections that is nearing completion…
- Conditions
- Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
- Trial name
- NCT04544683
- Testing
- Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Utah
Degenerative Cervical Disc Disease
PRESTIGE Observational Study
Prestige artificial disc replacement is an alternative treatment option with 16 years of experience addressing the unmet needs of surgical fusion interventions.
- Trial name
- NCT00875810
- Where
- 26 sites in Czechia, Greece and 6 more
- Volunteers
- 194 people
- Sponsor
- Medtronic Spinal and Biologics
Cervical Degenerative Disc Disease
Real World Data Collection on the Synergy Disc
This is a real world data collection observational study at a single site. There are both prospective and retrospective cohorts.
- Trial name
- NCT06383949
- Testing
- Synergy Cervical Disc system
- Where
- Ireland
- Volunteers
- 50 people
- Sponsor
- Synergy Spine Solutions
Cervical Degenerative Disc Disorder
Post Approval Study Protocol for the Two Level Simplify® Cervical Artificial Disc
This study is intended to demonstrate the 5-year long-term safety and efficacy of the Simplify® Cervical Artificial Disc ("Simplify Disc") in subjects enrolled in the non-randomized two-level Simplify Disc Investigational Device…
- Trial name
- NCT04980378
- Testing
- Simplify Disc
- Where
- 18 sites in United States
- Volunteers
- 291 people
- Sponsor
- NuVasive