Clinical trials: Cervical Neoplasms
HPV
Self-sampling for Human Papillomavirus (HPV) Among Patients Receiving Colposcopy
This study seeks to compare the accuracy and acceptability of HPV testing self-sampling kit and standard clinician-sampling for HPV testing.
- Trial name
- NCT04585243
- Testing
- Evalyn Brush
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Milton S. Hershey Medical Center
Oral Mucositis Due to Radiation
A Sequential Cohort Study Exploring GELCLAIR in the Management of Oral Mucositis in Patients Receiving Radical Radiation for Head and Neck Cancer
The goal of this clinical trial is to learn if Gelclair lubricant gel can help manage Oral Mucositis (OM) among Oropharyngeal and Oral cavity cancer patients receiving radiation treatment.
- Trial name
- GOMS (NCT06897215)
- Testing
- Hyaluronic acid hydrogel
- Volunteers
- 48 people
- Sponsor
- Nova Scotia Health Authority
Nasopharyngeal Carcinoma
Camrelizumab Plus Stereotactic Body Radiotherapy vs Camrelizumab Alone For Oligometastatic Nasopharyngeal Carcinoma
We intend to compare the efficacy and safety of immunotherapy plus stereotactic body radiotherapy at oligometastatic lesions and immunotherapy alone among patients with oligometastatic nasopharyngeal carcinoma whose primary…
- Trial name
- NCT04944914
- Testing
- camrelizumab, stereotactic body radiotherapy
- Where
- China
- Volunteers
- 188 people
- Sponsor
- Sun Yat-sen University
Esophageal Cancer, Neoplasms, Esophageal
Trial of XELOX Followed by Radiation Combined With Carboplatin and RAD001 for Esophageal Cancer
The purpose of this study is to test the drug RAD001 in combination with another chemotherapy drug, Carboplatin, as well as radiation therapy in the treatment of esophageal cancer.
- Trial name
- NCT01490749
- Testing
- RAD001, XELOX, Carboplatin
- Where
- 3 sites in United States
- Volunteers
- 17 people
- Sponsor
- Emory University
Locally Recurrent Head and Neck Cancer
Salvage Brachytherapy and Hyperthermia for Recurrent H&N-tumours
The aim of the present trial is to assess the prospective results of protocol-based interstitial pulsed-dose-rate (PDR) brachytherapy with interstitial hyperthermia (iHT) in a group of selected patients where salvage surgery with…
- Trial name
- HyBT-H&N (NCT03238378)
- Testing
- Brachytherapy, Hyperthermia
- Where
- Germany
- Volunteers
- 96 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Head and Neck Cancer
Pilot Study to Evaluate Photoacoustic Imaging in Head and Neck Cancer
In this study, PA imaging will be used to examine the physiological and physical changes in lymph node involvements of head and neck cancer during radiotherapy with or without chemotherapy.
- Trial name
- NCT04428515
- Testing
- Photoacoustic Imaging System
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Sunnybrook Health Sciences Centre
Uterine Cervical Neoplasms
Imaging the Uterine Cervix - UltraSightHD™
The purpose of this study is to investigate the performance ability of the UltraSightHD™. The instrument will be assessed on characteristics such as focus quality, ability to image the entire cervix, and illumination.
- Trial name
- NCT01090635
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- STI-Medical Systems
Hypopharyngeal Cancer
New Strategy of Improving Treatment Outcome and Larynx-preservation Rate in Locally Advanced Hypopharyngeal Carcinoma
To develope stratification treatment for the patients who have locally advanced hypopharyngeal carcinoma. Experimental group patients were treated individually according to the response status after induction chemotherapy…
- Trial name
- NCT03558035
- Testing
- Induction CT+ CRT group, Concurrent CRT group
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Chinese Academy of Medical Sciences
Head and Neck Cancer, Paranasal Sinus Cancer
Adaptive Radiotherapy for Head and Neck Cancer
The purpose of this study is to demonstrate that adaptive radiotherapy (ART) in head and neck cancer patients are comparable to historical controls in head and neck patients undergoing standard intensity-modulated radiation…
- Conditions
- Head and Neck Cancer, Paranasal Sinus Cancer, Oropharynx Cancer, Oral Cavity Cancer
- Trial name
- NCT03096808
- Testing
- Adaptive Radiotherapy
- Where
- 8 sites in United States
- Volunteers
- 64 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Head and Neck Cancer
Erlotinib and Docetaxel With Concomitant Boost Radiation Therapy (XRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)
The goal of this clinical research study is to find the highest safe dose of the drugs OSI-774 and docetaxel that can be given together along with radiation treatment for advanced head and neck cancer.
- Trial name
- NCT00113347
- Testing
- Erlotinib, Docetaxel, Radiation Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center
Tumor Disease Including Colorectal Cancer, Head & Neck Squamous Cell Carcinoma
Assessment and Prediction of Cetuximab-Induced Hypersensitivity Reactions Using Cetuximab Specific IgE Detection
1. Background Cetuximab (trade name Erbitux) is a murine-human chimeric monoclonal antibody to human epidermal growth factor receptor (EGFR). This drug has been used as a treatment for colorectal cancer and head and neck cancer.
- Trial name
- NCT03485638
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Yonsei University
Head and Neck Squamous Cell Carcinoma, Quality of Life
Enteral Omega 3 During Radiotherapy to Improve the Quality of Life and Functionality of Head and Neck Cancer Patients
Health-related Quality of Life (QoL) is a multidimensional construct that allows us to know the patient's perception of well-being, and how this perception is related to their illness and treatment.
- Conditions
- Head and Neck Squamous Cell Carcinoma, Quality of Life, Radiotherapy; Complications
- Trial name
- NCT03720158
- Testing
- Omega 3 Group
- Where
- Mexico
- Volunteers
- 9 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Cervical Dysplasia, Uterine, Vaginal Dysplasia
Clinical, Translational and Biomarker-Based Female Genital HPV Induced Dysplasia and Cancer Screening Study Using Cf-HPV-DNA Blood Tests
Uterine cervical dysplasia and other female genital dysplasia continue to be significant health problems despite Cervical Screening Programs and HPV vaccinations being available.
- Conditions
- Cervical Dysplasia, Uterine, Vaginal Dysplasia, Vulvar Dysplasia
- Trial name
- TTMV HPV DNA (NCT05536843)
- Volunteers
- 500 people
- Sponsor
- University of Mississippi Medical Center
Head and Neck Cancer
Identification and Characterization of Novel Proteins and Genes in Head and Neck Cancer
Through this study, we hope to learn more about the mechanisms, which may contribute to development and progression of head and neck cancer.
- Trial name
- NCT00230308
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Stanford University
Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7
Intensity-Modulated Proton Beam Therapy or Intensity-Modulated Photon Therapy in Treating Patients With Stage III-IVB Oropharyngeal Cancer
This randomized phase III trial studies the side effects and how well intensity-modulated proton beam therapy works and compares it to intensity-modulated photon therapy in treating patients with stage III-IVB oropharyngeal…
- Conditions
- Stage III Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IVA Oropharyngeal Squamous Cell Carcinoma AJCC v7, Stage IVB Oropharyngeal Squamous Cell Carcinoma AJCC v7
- Trial name
- NCT01893307
- Testing
- Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis, Photon Beam Radiation Therapy
- Where
- 22 sites in United States
- Volunteers
- 440 people
- Sponsor
- M.D. Anderson Cancer Center
Cervical Cancer, Stage IIB
Curcumin in Advanced Cervical Cancer
Determine the efficacy and safety of turmeric in the treatment of patients with advanced cervical cancer. Efficacy will be determined through radiological and histopathological criteria through the rate of response to treatment…
- Trial name
- NCT04294836
- Testing
- Curcumin
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Metastatic Cancer, Cervical Cancer
Triage of Advanced Cervical Cancer Through Immunotherapy Induction (TRACTION)
To learn if MGD019 can help to control cervical cancer in patients who have yet to receive treatment.
- Trial name
- NCT05475171
- Testing
- Lorigerlimab
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Esophageal Cancer, Oesophageal Cancer
PULSO Trial: Pulsed Low-Dose-Rate (PLDR) Radiation Chemoradiation (CRT) vs. Standard CRT for Esophageal Cancer
This is a prospective, randomized, open-label, two-arm phase 2 trial that will evaluate whether the use of Pulsed Low-Dose-Rate radiation technique, as compared to standard radiation, is associated with reduced rates of…
- Conditions
- Esophageal Cancer, Oesophageal Cancer, GastroEsophageal Cancer
- Trial name
- NCT06906887
- Testing
- Induction Chemotherapy (modified FLOT or modified FOLFOX-6), Chemotherapy, Conventional Radiation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical College of Wisconsin
Laryngeal Squamous Cell Carcinoma
Immunohistochemical Expression of Excision Repair Cross Complementation Group 1 (ERCC1) in Laryngeal Squamous Cell Carcinoma and Its Correlation With Response to Radiotherapy.
1. Determine the correlation between immunohistochemical expression of ERCC1 in laryngeal cancer cells with clinico-pathological variables. 2. Assess the correlation between ERCC1 expression and response to radiotherapy.
- Trial name
- NCT05832593
- Testing
- Immunohistochemistry
- Volunteers
- 52 people
- Sponsor
- Assiut University
Oropharyngeal Cancer, Squamous Cell Carcinoma to the Head and Neck
A Pilot Study at a Single-Institution of Pregabalin in the Management of Mucositis Pain in Patients Undergoing Chemoradiation Therapy to the Head and Neck.
To assess the efficacy of pregabalin in the management of mucositis pain in patients receiving radiotherapy to the head and neck.
- Trial name
- NCT02277548
- Testing
- Lyrica 300 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
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