Clinical trials: Cervical Spinal Cord Paralysis
Individuals With C6-C7 Tetraplegia (AIS A or B)
Grasping Rehabilitation Using Motor Imagery With or With no Neurofeedback After Tetraplegia
Motor imagery has shown promising results to optimize tenodesis grasp in individuals with C6-C7 tetraplegia. However, efficacy of using motor imagery to improve grasping after tetraplegia requires further study with higher level…
- Trial name
- TETRAMINF (NCT03190863)
- Testing
- Motor imagery combined with neurofeedback (MINF), Motor imagery (MI), Control (C)
- Where
- 2 sites in France
- Volunteers
- 21 people
- Sponsor
- Hospices Civils de Lyon
Hemiplegic Cerebral Palsy
Spinal Cord Associative Plasticity in Cerebral Palsy
Associative plasticity has been used to promote functional recovery from conditions affecting movement. The long term goal of this project is to use electrical stimulation techniques to improve arm and hand function.
- Trial name
- SCAP-CP (NCT07607665)
- Testing
- Paired brain and nerve stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Columbia University
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Brain Plus Spinal Stimulation for Cervical SCI
The goal of this project is to strengthen residual corticospinal tract (CST) connections after partial injury using combined motor cortex and spinal cord stimulation to improve arm and hand function after spinal cord injury…
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
- Trial name
- NCT04727866
- Testing
- transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Spinal Cord Injury Cervical
Functional Electrical Stimulation (FES) and Reconstructive Tetraplegia Hand and Arm Surgery
FES is a common and established method in the rehabilitation of persons with spinal cord injury (SCI). Some known effects of FES were investigated in several studies e.g.
- Trial name
- FES (NCT03048331)
- Testing
- Functional Electrical Stimulation
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Spastic Tetraplegia, Pain
ESWT for UE Pain in Patients With Cervical Spinal Cord Injury
This study aimed to investigate the efficacy and safety of extracorporeal shockwave therapy (ESWT) for upper extremity pain related to spasticity in patients with spinal cord injury.
- Conditions
- Spastic Tetraplegia, Pain, Myelopathy Cervical
- Trial name
- NCT04319679
- Testing
- Extracorporeal shockwave therapy
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Bundang CHA Hospital
Spinal Cord Injuries
Duroplasty for Injured Cervical Spinal Cord With Uncontrolled Swelling
QUESTION. Does duroplasty improve outcome after spinal cord injury? WHAT DO WE STUDY? We will investigate whether performing a surgical procedure called duroplasty improves outcomes after spinal cord injury.
- Trial name
- DISCUS (NCT04936620)
- Testing
- Duroplasty, Spinal surgery
- Where
- 34 sites in Austria, Belgium and 10 more
- Volunteers
- 222 people
- Sponsor
- St George's, University of London
Cervical Spinal Cord Injury, Tetraparesis
Spinal Cord Neuromodulation for Spinal Cord Injury
This study is designed to assess the strategy of using spinal cord stimulation to improve the ability to move in spinal cord injured humans.
- Conditions
- Cervical Spinal Cord Injury, Tetraparesis, Tetraplegia
- Trial name
- NCT02313194
- Testing
- Epidural Stimulation, Buspirone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of California, Los Angeles
Spinal Cord Injuries, Spinal Cord Diseases
Stimulation With Wire Leads to Restore Cough
The purpose of this trial is to determine the efficacy of spinal cord stimulation, using wire leads, to produce an effective cough in patients with spinal cord injuries.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases
- Trial name
- NCT01659541
- Testing
- Expiratory muscle stimulator, Implantation of device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- MetroHealth Medical Center
Cervical Spinal Cord Injury, Spine Injury
Dose Escalation Study of AST-OPC1 in Spinal Cord Injury
The purpose of this study is to evaluate the safety of cross sequential escalating doses of AST-OPC1 administered among 5 cohorts at a single time-point between 21 and 42 days post injury, inclusively, to subjects with subacute…
- Conditions
- Cervical Spinal Cord Injury, Spine Injury, Spinal Cord Trauma
- Trial name
- NCT02302157
- Testing
- AST-OPC1
- Where
- 9 sites in United States
- Volunteers
- 25 people
- Sponsor
- Lineage Cell Therapeutics, Inc.