Clinical trials: Cervical Spine
Cervical Spine Degenerative Disease
AO CSH Mainstream Study on Cervical Spine Degeneration
Adult patients with cervical degenerative diseases undergoing primary anterior and/or posterior cervical fusion will be prospectively enrolled from participating sites.
- Trial name
- CASDEM (NCT06845293)
- Volunteers
- 300 people
- Sponsor
- AO Innovation Translation Center
Cervical Spine Disease, Pain, Postoperative
Clinical Study on the Safety and Efficacy of the Minimally Invasive Ennovate® Method for Pedicle Screw Placement
The study's main purpose is the collection of clinical data on the patients benefit and safety of pedicle screw placement through an innovative minimally invasive surgical approach compared to the state of the art open surgical…
- Trial name
- MISPEC (NCT06960018)
- Testing
- Ennovate® Cervical, open surgical technique, Ennovate® Cervical, minimal invasive surgical technique
- Where
- 3 sites in Germany
- Volunteers
- 76 people
- Sponsor
- Aesculap AG
Neck Pain
Thoracic Manipulation and Mobilization for Neck Pain
The purpose of this randomized clinical trial was to examine the widespread effects of thoracic spine thrust manipulation and thoracic non-thrust mobilization on pressure pain sensitivity and neck pain intensity in patients with…
- Trial name
- NCT02051478
- Testing
- Thoracic mobilization, Thoracic manipulation
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Universidad Rey Juan Carlos
Neck Pain
Different Types of Manual Therapy Techniques in Patients With Chronic Neck Pain
The purpose of this study was to investigate the comparative effectiveness of high velocity and low amplitude (HVLA)vs Mobilization (Mob) vs Mobilization with movement technique (MWMT) in sample of patients with chronic neck pain…
- Trial name
- CNP (NCT01792895)
- Testing
- Manipulation, Mobilization, Mobilization with movement
- Where
- Spain
- Volunteers
- 61 people
- Sponsor
- Universidad Rey Juan Carlos
Cervical Spine Motion Assessment in Healthy Adults
Assessing the Validity and Reliability of IMU Systems and a Goniometer in Cervical Motion (VIRGO-CM)
This study aims to evaluate how accurate and reliable two wearable sensor systems (inertial measurement units or IMUs) and a goniometer are in measuring cervical spine (neck) motion.
- Trial name
- VIRGO-CM (NCT07117292)
- Testing
- Xsens DOT, Trigno Avanti Sensors, Universal Goniometer
- Where
- Cyprus
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- European University Cyprus
Whiplash Injury of Cervical Spine
Effects of a Mobile App on Adherence to Daily Exercise and Recovery After Whiplash Injury
This study investigates the effect of daily mobile app reminders to exercise in conjunction with standard physical therapy on adherence to exercise and recovery after whiplash injury of the neck.
- Trial name
- NCT05704023
- Testing
- Reminder to exercise
- Where
- Croatia
- Volunteers
- 68 people
- Sponsor
- Blaz Barun
Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation
Multicentric Registry for the Detection of C5 Palsy After Anterior Cervical Discectomy and Fusion
Detect the reason for the frequently occurring C5 palsy after anterior cervical discectomy and fusion
- Conditions
- Degenerative Cervical Spinal Stenosis, Cervical Disc Herniation, Suspected Cervical Spine Instability
- Trial name
- C5registry (NCT02875431)
- Testing
- Patients undergo ACDF or cervical vertebral body replacement
- Where
- Germany
- Volunteers
- 1,087 people
- Sponsor
- Technical University of Munich
Neck Pain
Patients With Neck Pain Likely to Benefit From Thoracic Spine Thrust Mobilization
Recently a clinical prediction rule (CPR) has been developed that identifies patients with neck pain who are likely to respond rapidly and dramatically to thoracic spine thrust manipulation and an active range of motion exercise.
- Trial name
- NCT00504686
- Testing
- manual therapy, exercise
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Franklin Pierce University
Pain, Postoperative, Pain, Acute
Opioid Sparing Anesthesia in Cervical Spine Surgery
The aim of this double blind randomized study will be to investigate the effect of an opioid-free anesthesia regimen with a mixture of lidocaine and ketamine in the same syringe versus remifentanyl analgesia in cervical spine…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chronic, Pain, Nociceptive
- Trial name
- NCT05717361
- Testing
- ketamine-lidocaine, Remifentanil
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Evangelismos Hospital
Neck Pain
Muscle and Biomechanical Factors in Football-Related Neck Pain
The study aims to analyze the influence of muscular and biomechanical characteristics of the cervical spine on the onset and progression of neck pain in collegiate football players.
- Trial name
- NCT07423052
- Testing
- Time over a regular football season
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Université du Québec à Trois-Rivières
Cervical Pedicle Screw
Analysis of Sub Axial Cervical Pedicle Spine Based on CT
The aim of study to analyze morphometry of sub axial cervical spine pedicle in an Egyptian population based on computed tomography (CT) and thus asses the safety and feasibility of cervical pedicle screw in the sub axial cervical…
- Trial name
- NCT06445348
- Testing
- Cervical pedicle screw
- Volunteers
- 80 people
- Sponsor
- Assiut University
Spinal Cord Injuries
Brainwave Control of a Wearable Robotic Arm for Rehabilitation and Neurophysiological Study in Cervical Spine Injury
CSI:Brainwave is a multidisciplinary neurophysiological project, developed by the Lab of Medical Physics, School of Medicine, Aristotle University of Thessaloniki and supported by two Neurosurgical Departments.
- Trial name
- CSI:Brainwave (NCT02443558)
- Testing
- Brain-Computer Interface control of robotic arms., MERCURY v2.0 robotic arms
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Intubation, Intratracheal
Tracheal Intubation Using Videolaryngoscope vs Fiberoptic Bronchoscope in Patients With Cervical Immobilization
In patients with suspected cervical spine injury, cervical immobilization, such as manual in-line stabilization or cervical collar has been adopted to prevent further neurologic injury due to cervical motion.
- Trial name
- NCT03759561
- Testing
- intubation with videolaryngoscope vs fiberoptic bronchoscope
- Where
- South Korea
- Volunteers
- 340 people
- Sponsor
- Seoul National University Hospital
Low Back Pain, Neck Pain
Pre-Visit AI Symptom-Checking and Shared Decision-Making in Spine Physical Therapy
Artificial intelligence (AI) symptom-checking tools, including large language models such as ChatGPT, are increasingly used by patients before they seek care.
- Conditions
- Low Back Pain, Neck Pain, Radiculopathy
- Trial name
- NCT07733752
- Testing
- re-visit AI symptom-checker use
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Neck Pain
Short-Term Response of Thoracic Spine Manipulation With or Without Trigger Point Dry Needling for Mechanical Neck Pain
This study will assess the short term response of thoracic spinal manipulation with or without trigger point dry needling in 58 subjects with a primary complaint of mechanical neck pain.
- Trial name
- NCT02415660
- Testing
- Thoracic spinal manipulation, Trigger point dry needling, Cervical range of motion exercises
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Brooke Army Medical Center
Intubation; Difficult or Failed
Comparison of Two Different Lightwand Intubation Techniques in Cervical Immobilized Patients
This study compares two different approaches of lightwand intubation techniques in cervical immobilized patients.
- Trial name
- NCT06119360
- Testing
- Face-to-face approach, Conventional approach
- Where
- South Korea
- Volunteers
- 176 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Cervical Disc Degeneration
Comparison of Rigid and Non-Rigid Interbody Fusion Device for Cervical Degenerative Disc Disease in Adults
Rigid interbody fusion device in bulk configuration has been widely used in anterior cervical discectomy and fusion (ACDF) surgery.
- Trial name
- NCT04550923
- Testing
- Z-Brace interbody fusion device, PEEK interbody fusion device
- Where
- 13 sites in Taiwan
- Volunteers
- 180 people
- Sponsor
- National Taiwan University Hospital
Cervical Spine Injury, Emergencies
CT C-spine Audit and Feedback
This is a prospective quality improvement study to assess the effect of using an audit-and-feedback process for emergency providers on utilization of computed tomography of the cervical spine.
- Conditions
- Cervical Spine Injury, Emergencies, Trauma
- Trial name
- NCT05711134
- Testing
- Audit and Feedback on Individual Practice Patterns
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Massachusetts, Worcester
Pain, Back Pain
Development of STEPPT
This 6-month pilot study aims to assess the feasibility, acceptability, and estimate effect sizes of the pilot STEPPT intervention for addressing ethnic disparities in physical therapy referrals and adherence between Hispanic and…
- Conditions
- Pain, Back Pain, Low Back Pain, Chronic Pain
- Trial name
- STEPPT PILOT (NCT06835439)
- Testing
- STEPPT Pilot, Standard Care (Control)
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- San Diego State University
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University