Clinical trials: Cervical Spine Disease
Discopathy, Herniated Cervical Disc
Post Market Clinical Follow up Study With the Cervical Disc Prothesis MOVE®-C
Study design: International, prospective, multicentre, non-randomised, observational study according to § 23b MPG. Objectives: Observational study to confirm the safety and performance of the cervical disc prosthesis MOVE®-C.
- Conditions
- Discopathy, Herniated Cervical Disc, Stenoses, Spinal, Radiculopathy
- Trial name
- PMCF_MOVE®-C (NCT05035693)
- Testing
- MOVE®-C
- Where
- 7 sites in Austria, Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- NGMedical GmbH
Spine Injuries and Disorders, Pain, Chronic
Real-Time Accurate Pathology Inspection and Decompression Study
The primary objective is changes in spine and lower limb pain following a laser-assisted neural decompression (LAND) procedure for the treatment of lumbar, thoracic, or cervical spine and/or extremity pain.
- Conditions
- Spine Injuries and Disorders, Pain, Chronic, Pain, Back, Pain, Neck
- Trial name
- RAPID (NCT05347108)
- Testing
- laser-assisted neural decompression (LAND) procedure
- Where
- United States
- Sponsor
- KM Clinical Research Group
Cervical Spondylotic Myelopathy
Diffusion MRI in Cervical Spondylotic Myelopathy (CSM)
Patients who have been diagnosed with Cervical Spondylotic Myelopathy will be asked to undergo an MRI using diffusion basis spectrum imaging (DBSI) technology.
- Trial name
- CSM (NCT03296592)
- Testing
- MRI with DBSI technology
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Degenerative Instability, Spondylolisthesis
PMCF Study on the Safety and Performance of CESPACE 3D
Prospective, pure data collection of all CeSPACE 3D patients in selected centers (not interventional, multicenter)
- Conditions
- Degenerative Instability, Spondylolisthesis, Post-discectomy Syndrome, Post-traumatic Instabilities
- Trial name
- CATALINA (NCT04477447)
- Where
- 2 sites in Germany
- Volunteers
- 101 people
- Sponsor
- Aesculap AG
Degenerative Disc Disease (DDD)
Kineflex|C Artificial Disc System to Treat Cervical Degenerative Disc Disease (DDD)
The purpose of this study is to show that the Kineflex|C Spinal System is no worse than conventional Anterior Cervical Diskectomy with Fusion (ACDF) in patients with single level degenerative disc disease at any cervical level…
- Trial name
- NCT00374413
- Testing
- Artificial disk, Artificial disc
- Where
- 21 sites in United States
- Volunteers
- 343 people
- Sponsor
- SpinalMotion
Cervical Spondylosis Symptomatic Neurological Compression
Collar Immobilization Following a Posterior Cervical Laminectomy and Fusion
Cervical collars are commonly used to provide external immobilization after elective Posterior Cervical Laminectomy and Interbody Fusion (PCLIF).
- Trial name
- NCT01383876
- Testing
- Collar, No Collar
- Where
- 2 sites in United States
- Volunteers
- 11 people
- Sponsor
- Brigham and Women's Hospital
Nasal Obstruction, Arthrosis
Role of Airtraq Mobile to Improve Intubation Conditions With Airtraq
Airtraq sp has been proven effective for intubating patients presenting with difficult airway. The Airtraq sp allows visualisation of the tracheal inlet only for the intubator.
- Trial name
- AirtraqMob (NCT02510924)
- Testing
- Tracheal intubation
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis
Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion
The purpose of this study is to evaluate the safety and preliminary efficacy of NeoFuse in subjects with a diagnosis of degenerative disc disease (DDD) at 2 or more adjacent cervical vertebral levels between C3-C4 to C7-T1.
- Conditions
- Cervical Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Trial name
- NCT01106417
- Testing
- NeoFuse, MasterGraft Granules
- Where
- 2 sites in Australia
- Volunteers
- 12 people
- Sponsor
- Mesoblast, Ltd.
Adjacent Segment Disease, Cervical Myelopathy
Adjacent Segment Disease After Anterior Cervical Decompression Surgery
Radiculopathy and/or myelopathy due to cervical degenerative disc disease are increasingly common pathologies in our ageing population. Both can be treated non-surgically or surgically.
- Conditions
- Adjacent Segment Disease, Cervical Myelopathy, Cervical Radiculopathy, Degenerative Disc Disease
- Trial name
- ASDafterACDF (NCT04320043)
- Testing
- Anterior cervical decompression
- Where
- Netherlands
- Volunteers
- 673 people
- Sponsor
- Zuyderland Medisch Centrum
Cervical Spondylosis
Effectiveness and Safety of Mobile Artificial Cervical Vertebrae Replacement for Patients With Cervical Spondylosis
The research team designed an artificial cervical joint prosthesis suitable for subtotal resection of the lower cervical vertebral body.
- Trial name
- NCT04813211
- Testing
- mobile artificial cervical vertebrae replacement, anterior cervical corpectomy and fusion
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Xi'an International Medical Center Hospital
Multiple Sclerosis, Muscle Spasticity
Effect of Cervical Mobilization on Balance and Plantar Pressure Distribution in Multiple Sclerosis
MS patients were randomly divided into traditional therapy and traditional therapy + cervical mobilization groups. While muscle strengthening, stretching, balance and coordination exercises were given to the traditional group…
- Conditions
- Multiple Sclerosis, Muscle Spasticity, Pressure Area, Cervical Region Disorder Nos
- Trial name
- NCT04543448
- Testing
- Traditional Rehabilitation for multiple sclerosis, Cervical mobilization for multiple sclerosis
- Where
- Turkey (Türkiye)
- Volunteers
- 12 people
- Sponsor
- Hasan Kalyoncu University
Cervical Radiculopathy, Cervical Myelopathy
The Collar Post Anterior Cervical Spine Surgery Study
The Anterior Cervical Discectomy and Fusion (ACDF) represents one of the most commonly performed spinal operations internationally, often in the context of symptomatic radiculopathy or myelopathy secondary to cervical…
- Trial name
- C-PASS (NCT03842072)
- Testing
- Cervical collar
- Where
- 2 sites in Canada
- Volunteers
- 244 people
- Sponsor
- Unity Health Toronto
Pain, Myofacial, Pain, Neck
Does Dry Needling Affect Treatment Outcomes of Interlaminar Epidural Steroid Injection in Cervical Disc Herniation?
Chronic neck pain is among the most frequently seen chronic painful conditions. As an important cause of disability, chronic neck pain is a musculoskeletal disorder that negatively affects quality of life.
- Conditions
- Pain, Myofacial, Pain, Neck, Pain, Chronic
- Trial name
- NCT04914637
- Testing
- Cervical interlaminar epidural steroid injection, Dry needling
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Marmara University
Dizziness, Balance; Distorted
Effects of Gaze Stabilization Exercises on Dizziness, Balance and Quality of Life in Cervical Spondylosis Patients
To determine the effects of gaze stabilization exercises on dizziness, balance and quality of life in patients with cervical spondylosis.
- Conditions
- Dizziness, Balance; Distorted, Cervical Spondylosis
- Trial name
- NCT05707130
- Testing
- gaze stabilization exercises, neck isometrics
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Opioid Use, Spinal Diseases
Opioid Free vs. Standard Perioperative Pain Regimen for Anterior Cervical Discectomy and Fusion (ACDF) Surgery
Patients undergoing 1-3 level Anterior Cervical Discectomy and Fusion (ACDF) at the levels between C2 and T1 will be enrolled into this randomized prospective study.
- Conditions
- Opioid Use, Spinal Diseases, Surgery--Complications, Surgery
- Trial name
- NCT04990804
- Testing
- Opioid Analgesic, Opioid-Free Postoperative Pain Regimen
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Vanderbilt University Medical Center
Temporomandibular Joint Dysfunction Syndrome
Manual Therapy and Exercises Applied to Cervical Spine in Patients With Temporomandibular Disorders
The objective of this study was to investigate the effect of a manual therapy and exercise program, focused on the rehabilitation of cervical function, on clinical signs and mandibular function in subjects with TMD.
- Trial name
- NCT01954511
- Testing
- Manual therapy, Pressure biofeedback device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Ossification of the Posterior Longitudinal Ligament
A Prospective Study Comparing the Efficacy of Laminoplasty and Laminectomy With Fusion for Ossification of the Posterior Longitudinal Ligament With High Occupation Rate in Cervical Spine
The efficacy of laminoplasty and laminectomy with fusion for ossification of the posterior longitudinal ligament with high occupation rate in the cervical spine is not clear in the literature report so far.
- Trial name
- NCT05019001
- Testing
- Laminoplasty, Laminectomy With Fusion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University Third Hospital
Postural Kyphosis, Postural Lordosis
Investigating Association Between Spine, Scapular, Shoulder and Core in Swimmers
The aim of this observational study is to investigate relationship between cervical, thoracic, lumbar and thoracolumbar spine posture, spine movement, isometric and eccentric shoulder strength, scapular dyskinesis and core muscle…
- Conditions
- Postural Kyphosis, Postural Lordosis, Movement, Abnormal, Spine Injury
- Trial name
- NCT06326177
- Testing
- Spine Posture Assessment, Spine Movement Assessment, Core Muscle Endurance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Yeditepe University
Cervicogenic Headache
Effects of Sustained Natural Appophyseal Glide Versus Rocababo 6x6 Program in Subjects With Cervicogenic Headache.
The purpose of this study is to investigate the effects of TMJ directed treatment approach using the Rocabado 6x6 program in patients with cervicogenic headache on the intensity of headache, function of the neck, and quality of…
- Trial name
- NCT05865808
- Testing
- cervical spine mobilization, Rocabado 6x6
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Whiplash Injury of Cervical Spine, Osteopathia
The Effectiveness of Osteopathic Treatment in Cervical Whiplash.
Introduction. Whiplash is common after road traffic accidents and affects millions of people worldwide; 50% develop chronic symptoms and 15% have their ability to work compromised.
- Conditions
- Whiplash Injury of Cervical Spine, Osteopathia, Quality of Life, Chronic Pain Syndrome
- Trial name
- NCT06334978
- Testing
- Osteopathic intervention
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla