Clinical trials: Cervix
Adenocarcinoma of the Uterine Cervix
Adenocarcinoma of the Uterine Cervix and HPV
The present study will mainly aim to review and characterize the pathologic features, treatment options, and follow-up outcomes of women with in situ/microinvasive adenocarcinoma of the uterine cervix according to HPV status…
- Trial name
- NCT05267834
- Testing
- Conization and/or Hysterectomy
- Where
- Italy
- Volunteers
- 148 people
- Sponsor
- Università Politecnica delle Marche
Preterm Birth
Direct Measurements of Cervical Remodeling for Predicting Preterm Birth
Racism and health care system distrust are potent stressors and may be associated with preterm birth (PTB). Additionally, cervical shortening is a common pathway leading to PTB.
- Trial name
- NCT01175551
- Where
- 2 sites in United States
- Volunteers
- 1,207 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Cervical Cancer
A Novel Smart Speculum Versus a Standard Speculum for Easy Visualisation of the Cervix and Performing Remote Cervical Cancer Screening
Objective: The main objective of this study is to verify the level of comfort for patients and the degree of cervical visibility for health providers using a novel smart speculum compared to the standard speculum.
- Trial name
- NCT06359431
- Testing
- Novel Smart Speculum, Standard speculum
- Where
- Cameroon
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GICMED
Papilloma, Cervix Lesion
Effect of Natural Compounds on the Severity of HPV-induced Cervical Lesions
To test the efficacy of a newly-commercialized formula, 40 HPV-positive women displaying chronic cervicitis, mild dysplasia or moderate dysplasia.
- Trial name
- NCT05625308
- Testing
- Epigallocatechin gallate, Folic acid, Vitamin B12, and Hyaluronic Acid
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Lo.Li.Pharma s.r.l
Preterm Birth
Cervical Pessary in Women With Arrested Preterm Labor and Short Cervix
Preterm birth (PTB), defined as birth between 20 and 36 6/7 weeks, is responsible for the majority of the neonatal morbidity and mortality in the United States, and 35% of all U.S. healthcare spending on infants.
- Trial name
- PWK (NCT02849301)
- Testing
- Arabin cervical pessary
- Where
- Italy
- Sponsor
- Federico II University
Cold Exposure
Simulation Study on Advanced Medical Procedures Under Extreme Environments
Background: In emergency situations in mountainous regions, medical professionals are often required to perform advanced medical procedures swiftly and efficiently.
- Trial name
- SIMEX-MED (NCT06640595)
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Preterm Birth, Premature Birth
Prevention of sPTB With Early Cervical Pessary Treatment in Women at High Risk for PTB
Prevention of preterm birth (PTB) is a key factor for a positive short-term and long-term outcome of the newborn children as mortality and morbidity are inversely related to gestational age at delivery.
- Trial name
- Prometheus (NCT03418012)
- Testing
- cervical pessary, Control-Group
- Where
- 9 sites in Australia, Germany and 2 more
- Volunteers
- 310 people
- Sponsor
- Bürgerhospital Frankfurt
Cervical Cancer by FIGO Stage 2018
Daily Adaptive Radiation Therapy an Individualized Approach for Carcinoma of the Cervix
This is a single-arm, prospective, multi-center clinical trial designed to demonstrate that adaptive radiotherapy for locally advanced cervical cancer will translate into a decreased rate of acute gastrointestinal toxicity…
- Trial name
- ARTIA-Cervix (NCT05197881)
- Testing
- Varian Ethos Adaptive Radiation Therapy
- Where
- 5 sites in United States
- Volunteers
- 125 people
- Sponsor
- Varian, a Siemens Healthineers Company
Recurrent Cervix Cancer, Progressive Cervix Cancer
Niraparib in Combination With Dostarlimab in Patients With Recurrent or Progressive Cervix Cancer
The purpose of this research study is to test the safety of Niraparib and dostarlimab as a combination treatment and see what effects (good and bad) this combination treatment has on patients with recurrent or progressive cervix…
- Trial name
- STAR (NCT04068753)
- Testing
- Niraparib, dostarlimab
- Where
- 4 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Oklahoma
Cervical Cancer
Belotecan (CKD-602) in Recurrent or Progressive Carcinoma of Uterine Cervix
-list item one, The purpose of this study is to evaluate the overall response rate of belotecan (CKD-602) in recurrent or progressive carcinoma of uterine cervix
- Trial name
- NCT00430144
- Testing
- Belotecan(CKD-602)
- Where
- South Korea
- Volunteers
- 16 people
- Sponsor
- Sokbom Kang
Cervical Cancer
Prospective Study Assessing Emotional, Sexual and Quality of Life Concerns Of Women Undergoing Removal of the Cervix Versus Removal of the Uterus,Ovaries and Fallopian Tubes For Treatment Of Early Stage Cervical Cancer
The purpose of this study is to will help us understand how two treatments impact women with early stage cervical cancer: a radical hysterectomy, which removes the entire uterus, the ovaries, and fallopian tubes versus a radical…
- Trial name
- NCT00579787
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Head and Neck Cancers, Lung and Esophagus Cancers
Adaptive Pet Study
The purpose of this study is to determine the benefit of using positron emission tomography (PET) in addition to the standard (computed tomography) CT to plan radiation therapy for cancer treatment.
- Conditions
- Head and Neck Cancers, Lung and Esophagus Cancers, Anal, Cervix, Vulvar, Vaginal, and Endometrium Cancers
- Trial name
- NCT01908504
- Testing
- PET-CT
- Where
- United States
- Volunteers
- 271 people
- Sponsor
- Duke University
Cervical Cancer Stage IV, Vulvar Cancer, Stage IV
Antineoplaston Therapy in Treating Patients With Stage IV Cancer of the Cervix and/or Vulva
Current therapies for Stage IV Cancer of the Cervix and/or Vulva provide very limited benefit to the patient. The anti-cancer properties of Antineoplaston therapy suggest that it may prove beneficial in the treatment of Stage IV…
- Trial name
- NCT00003525
- Testing
- Antineoplaston therapy (Atengenal + Astugenal)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Burzynski Research Institute
Cervical Cancer
Post Market Clinical Follow-up Study Venezia
The investigational device is the Advanced Gynecological Applicator (AGA) Venezia configuration, an applicator to treat locally advanced stage cervical cancer.
- Trial name
- NCT03958357
- Testing
- Advanced Gynecological Applicator configuration
- Where
- 3 sites in Austria, Germany and 1 more
- Volunteers
- 41 people
- Sponsor
- Nucletron Operations BV
Precancerous Condition
Activating Collaborative CIS Support Via Targeted Provider Mailing
RATIONALE: Receiving a reminder letter from their doctor with questions to ask the Cancer Information Service may be more effective than a standard reminder letter in helping patients who have had an abnormal Pap test keep their…
- Trial name
- NCT00873288
- Testing
- Usual care mailing intervention, CIS support mailing intervention
- Where
- 2 sites in United States
- Volunteers
- 254 people
- Sponsor
- Northwestern University
Respiratory Disease of A Newborn
The Optimal Timing for Cerclage Removal
Women with a history of cervical insufficiency can be managed with elective cervical cerclage placed at the beginning of the second trimester. The McDonald technique is the most commonly used.
- Trial name
- NCT04151303
- Testing
- Cervical cerclage
- Where
- Israel
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Breast Cancer, Prostate Cancer
Tempus Priority Study: A Pan-tumor Observational Study
Observational study that will be collecting clinical and molecular health information from cancer patients who have received comprehensive genomic profiling and meet the specific eligibility criteria outlined for each cohort with…
- Conditions
- Breast Cancer, Prostate Cancer, Bladder Cancer, Lung Cancer
- Trial name
- NCT05179824
- Testing
- Observation
- Where
- 2 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Tempus AI
Papillomavirus Infections
Efficacy of 851B Gel for Treating High-Risk Cervical Human Papillomavirus Infection in Women.
The purpose of this study was to evaluate efficacy of 851B gel over a range of concentrations and dosing regimens on high-risk cervical human papillomavirus infection in women.
- Trial name
- NCT00312286
- Testing
- 851B
- Where
- 93 sites in United States, Canada and 1 more
- Volunteers
- 538 people
- Sponsor
- Takeda
Cervical Cancer, Precancerous Condition
Study of Pap Smears From Patients Enrolled on Clinical Trial GOG-171
RATIONALE: Studying Pap smears in the laboratory from women with atypical glandular cells of unspecified significance may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00898144
- Testing
- Papanicolaou test, laboratory biomarker analysis
- Volunteers
- 55 people
- Sponsor
- Gynecologic Oncology Group
HPV Disease, Cervical Intraepithelial Neoplasia Grade I
HIFU vs Observation for LSIL of Cervix: A Randomized Controlled Trial
The majority of low-grade pre-invasive lesions of cervix (low-grade squamous intraepithelial lesions, LSIL).will regress spontaneously over 2 years and immediate treatment may not be necessary.
- Trial name
- HIFU Colpo (NCT07461064)
- Testing
- HIFU treatment
- Volunteers
- 180 people
- Sponsor
- Queen Mary Hospital, Hong Kong