Clinical trials: Cervix
Primary Peritoneal Carcinoma, Tumor
Feasibility Study of Pazopanib in Combination With Chemotherapy in Gynaecological Tumors
This is an open-label, two-arm, multicenter feasibility study to evaluate the safety and tolerability of pazopanib in combination with carboplatin and paclitaxel in female subjects with newly diagnosed advanced gynaecological…
- Conditions
- Primary Peritoneal Carcinoma, Tumor, Epithelial Ovarian Cancer, Uterine Disease
- Trial name
- NCT00561795
- Testing
- pazopanib (GW786034), carboplatin, paclitaxel
- Where
- 5 sites in France, Germany
- Volunteers
- 12 people
- Sponsor
- GlaxoSmithKline
Cancer of the Uterine Cervix
Magnetic Resonance Imaging (MRI) Staging of Cervix Cancer
The researchers propose that it may be corpus invasion, rather than tumour volume per se, which is one of the important determinants of ultimate outcome in cervix cancer.
- Trial name
- NCT00193934
- Where
- 16 sites in United States, Australia and 3 more
- Volunteers
- 109 people
- Sponsor
- Trans Tasman Radiation Oncology Group
Uterine Cervical Dysplasia
Hemostatic Procedure After Biopsy of the Cervix
Cytological abnormalities of the Cervix uteri need to be clarified by colposcopy biopsy. To avoid bleeding after biopsy, monsel´s paste is a common used Agent.
- Trial name
- NCT02486471
- Testing
- Monsel´s Paste, Wait and see
- Where
- 2 sites in Germany
- Volunteers
- 166 people
- Sponsor
- Zydolab - Institute of Cytology and Immune Cytochemistry
Uterine Hemorrhage
Hysteroscopy and Misoprostol Project
To investigate if self-inserted vaginal misoprostol prior to outpatient hysteroscopy will lead to satisfactory cervical ripening, compared to placebo.
- Trial name
- NCT00363389
- Testing
- misoprostol and cervical ripening
- Where
- Norway
- Volunteers
- 86 people
- Sponsor
- Ullevaal University Hospital
Chemotherapy-induced Peripheral Neuropathy, Chemotherapeutic Toxicity
Cryotherapy vs. Cryocompression for Preventing Chemotherapy-induced-peripheral-neuropathy in Women Undergoing Chemotherapy
This study's aim is to show a benefit of Cryocompression (cooling hands with additional compression of the hands) in comparison to Cryotherapy (just cooling hands) in female cancer patients (with gynecological cancer) receiving…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapeutic Toxicity, Chemotherapeutic Agent Toxicity
- Trial name
- NCT04632797
- Testing
- Hilotherm Chemo Care
- Where
- Austria
- Volunteers
- 196 people
- Sponsor
- Medical University Innsbruck
HPV Vaccination, Pap Smear
Impact of HPV Vaccination to Catch up in the Emergence of Lesions of the Cervix
In France, the vaccination coverage observed for HPV vaccination is low for a full-scale regimen, and has been falling since 2010.
- Conditions
- HPV Vaccination, Pap Smear, Cervical Cancer, Catch-up Vaccination
- Trial name
- HPVAC (NCT03328013)
- Where
- France
- Volunteers
- 191 people
- Sponsor
- University Hospital, Brest
Uterine Cervical Dysplasia, Uterine Cervical Intraepithelial Neoplasia
Clinical Trial for the Use of a Novel Cell Collector Device to Retrieve Cells From the Uterine Cervix
This study tested the safety and performance of a new cell collector device and compared the results to those obtained with the current existing device that are being used routinely
- Conditions
- Uterine Cervical Dysplasia, Uterine Cervical Intraepithelial Neoplasia, Uterine Cervical Neoplasia, Uterine Cervical Cancer
- Trial name
- NCT00266084
- Volunteers
- 85 people
- Sponsor
- University Hospitals Cleveland Medical Center
Uterine Cervical Neoplasms, Squamous Cell Carcinoma
The Potential for Metformin to Improve Tumor Oxygenation in Locally Advanced Cervix Cancer: A Phase II Randomized Trial
Cervical cancer remains an important health problem worldwide. Poor tumor oxygenation (hypoxia) is associated with inferior survival in cervical cancer and resistance to radiation treatment.
- Conditions
- Uterine Cervical Neoplasms, Squamous Cell Carcinoma, Adenocarcinoma, Carcinoma, Adenosquamous
- Trial name
- NCT02394652
- Testing
- Metformin, Cisplatin, FAZA
- Where
- 5 sites in Canada
- Volunteers
- 16 people
- Sponsor
- University Health Network, Toronto
Cancer of Cervix
The Correlation Between the Haplotype of Human Leukocyte Antigen (HLA) and Human Papillomavirus
Cervical cancer is the most frequent neoplasm of women in Taiwan and in the world. It influences about 2,700 women with about 1,000 women dying of cervical cancer each year and in Taiwan.
- Trial name
- NCT00154479
- Where
- Taiwan
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Paclitaxel and Cisplatin or Topotecan With or Without Bevacizumab in Treating Patients With Stage IVB, Recurrent, or Persistent Cervical Cancer
This randomized phase III trial studies the side effects of paclitaxel when given together with cisplatin or topotecan with or without bevacizumab and to compare how well they work in treating patients with stage IVB, cervical…
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Recurrent Cervical Carcinoma
- Trial name
- NCT00803062
- Testing
- Bevacizumab, Cisplatin, Laboratory Biomarker Analysis
- Where
- 549 sites in United States, Spain
- Volunteers
- 452 people
- Sponsor
- National Cancer Institute (NCI)
High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion
Phase II Study of Dysplasix™ Intravaginal Suppositories in Patients Patients With High-Risk HPV and Mild Cervical Cytologic Abnormalities
The goal of this clinical trial is to learn if an investigational vaginal suppository therapy works to treat low-grade cervical lesions (ASC-US and LSIL) associated with high-risk human papillomavirus (hr-HPV) infection in women.
- Conditions
- High-risk HPV (Any Strain), LSIL, Low Grade Squamous Intraepithelial Lesion, ASC-US, HPV Infection
- Trial name
- NCT07572396
- Testing
- EGCG and Quinine Sulfate Vaginal Suppository
- Where
- Hong Kong
- Volunteers
- 45 people
- Sponsor
- Amplexd Therapeutics, Inc.
Metastatic Tumor, Advanced Solid Tumor
A Clinical Research About CD70-positive Advanced/Metastatic Solid Tumors Treated by CD70-targeted CAR-T
As a phase I clinical research，this study plans to evaluate the safety and tolerability of CD70-targeting CAR-T cells in the treatment of CD70-positive advanced/metastatic solid tumors, and obtain recommended doses and infusion…
- Conditions
- Metastatic Tumor, Advanced Solid Tumor, Renal Cell Carcinoma, Ovarian Cancer
- Trial name
- NCT05468190
- Testing
- CD70 CAR-T cells
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Chongqing Precision Biotech Co., Ltd
High-grade Cervical Intraepithelial Neoplasia
An Alternative Treatment for Cervical Intraepithelial Neoplasia Using the Focal Loop Electrosurgical Excision Procedure
This is a pilot study to test the short-term effectiveness of an alternative treatment approach for precancerous cells of the cervix.
- Trial name
- NCT02220192
- Testing
- Focal LEEP
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Alabama at Birmingham
Pleural Effusion, Malignant, Ascites, Malignant
Mass Response of Tumor Cells as a Biomarker for Rapid Therapy Guidance (TraveraRTGx)
The primary objective of this study, sponsored by Travera Inc. in Massachusetts, is to validate whether the mass response biomarker has potential to predict response of patients to specific therapies or therapeutic combinations…
- Conditions
- Pleural Effusion, Malignant, Ascites, Malignant, Carcinoma, Carcinoma, Hepatocellular
- Trial name
- TraveraRTGx (NCT05461430)
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Travera Inc
Preterm Birth
Preventing Preterm Birth With a Pessary
The primary objective of this study, is to determine the effect of a Cup pessary, a device that is currently readily available in the USA and similar in design to the Arabin pessary, on the incidence of delivery prior to 37 weeks…
- Trial name
- PrePPy (NCT01380158)
- Testing
- Cup pessary (Bioteque America, Inc)
- Where
- 3 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Cervical Cancer, HPV
CTCs in Cervix Cancer
This study is a validation study to confirm the ability of Telomescan OBP-401 to identify CTCs in patients with HPV 16 / 18 associated cervical cancer.
- Trial name
- NCT04064515
- Testing
- Blood Assayed for CTCs
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- NYU Langone Health
Carcinoma in Situ of Uterine Cervix, Cervical Intraepithelial Neoplasias
Multispectral Digital Colposcope With Probe for Detection of Cervical Intraepithelial Neoplasia
Although cervical cancer is a preventable cancer, every year more than one-quarter of a million women die worldwide from this disease.
- Conditions
- Carcinoma in Situ of Uterine Cervix, Cervical Intraepithelial Neoplasias, High Grade Cervical Intraepithelial Neoplasia
- Trial name
- MDCwProbe (NCT02406352)
- Testing
- Multispectral Digital Colposcope with probe
- Where
- United States
- Volunteers
- 618 people
- Sponsor
- Brookdale University Hospital Medical Center
Cervix, Cancer
Non-Invasive, Real-Time Technology for Diagnosis of Cervical Tissue
In general, to determine the sensitivity of light transport to tissue from morphological features of clinical significance. Determine how specific structural features contribute to light scattering.
- Trial name
- NCT00250055
- Testing
- Colposcopy, Spectroscopy, and Biopsy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of New Mexico
Cervix Neoplasms
The IMAP Study Improving Management of Mildly Abnormal Pap Smears
The study compares the psychosocial outcomes of different management strategies for women with minor atypia (including 'HPV effect') detected on Pap smears: conventional management (a repeat Pap smear at 6 months) versus Human…
- Trial name
- NCT00119509
- Testing
- HPV DNA testing, Conventional management (repeat Pap smear at 6 months), Decision aid with choice of management
- Where
- 7 sites in Australia
- Volunteers
- 300 people
- Sponsor
- University of Sydney
CIN, Cervix Cancer
HPV E6/E7 mRNA Versus HPV DNA as Triage for Cervical Cancer Screening
AIM: To develop and standardize a cost effective methodology or algorithm for mRNA E6/E7 for HPV genotypes 16, 18, 31, 33 and 45 as compared to commercially available assays which can be incorporated to triage excess false…
- Trial name
- PODBT (NCT02116920)
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Tata Memorial Hospital